AVPR2 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	AVPR2
Entrez Gene ID	403804
Full Name	arginine vasopressin receptor 2
General protein information	Preferred Names arginine vasopressin receptor 2 Names vasopressin V2 receptor AVPR V2 V2R antidiuretic hormone receptor arginine vasopressin receptor 2 (nephrogenic diabetes insipidus) renal-type arginine vasopressin receptor
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003177.1	NP_001003177.1	vasopressin V2 receptor
XM_022415491.1	XP_022271199.1	vasopressin V2 receptor isoform X1
XM_005640983.2	XP_005641040.1	vasopressin V2 receptor isoform X1
XM_005640983.3	XP_005641040.1	vasopressin V2 receptor isoform X1

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	AVPR2	NP_001003177.1
Danio rerio (zebrafish)	LOC100007585	XP_001346005.5
Homo sapiens (human)	AVPR2	NP_000045.1
Mus musculus (house mouse)	Avpr2	NP_062277.1
Rattus norvegicus (Norway rat)	Avpr2	NP_062009.1
Xenopus tropicalis (tropical clawed frog)	LOC100487051	XP_002937279.2
Bos taurus (cattle)	AVPR2	NP_776671.1
Danio rerio (zebrafish)	LOC100151502	XP_001922042.4
Pan troglodytes (chimpanzee)	AVPR2	XP_001145732.2
	AVPR2	XP_001088539.1

Gene Ontology
Bibliography

Related articles in PubMed

Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.
Feinstein TN, Yui N, Webber MJ, Wehbi VL, Stevenson HP, King JD Jr, Hallows KR, Brown D, Bouley R, Vilardaga JP
The Journal of biological chemistry288(39)27849-60(2013 Sep)

Expression of receptors for luteinizing hormone, gastric-inhibitory polypeptide, and vasopressin in normal adrenal glands and cortisol-secreting adrenocortical tumors in dogs.
Galac S, Kars VJ, Klarenbeek S, Teerds KJ, Mol JA, Kooistra HS
Domestic animal endocrinology39(1)63-75(2010 Jul)

Involvement of the V2 vasopressin receptor in adaptation to limited water supply.
B?selt I, R?mpler H, Hermsdorf T, Thor D, Busch W, Schulz A, Sch?neberg T
PloS one4(5)e5573(2009)

Characterization of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus in a polarized cell model.
Robben JH, Knoers NV, Deen PM
American journal of physiology. Renal physiology289(2)F265-72(2005 Aug)

Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium.
Nickols HH, Shah VN, Chazin WJ, Limbird LE
The Journal of biological chemistry279(45)46969-80(2004 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

vasopressin receptor type 2 signaling is controlled by retromer and arrestin in a noncanonical regulatory pathway
Title: Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.

ectopic expression of gastric-inhibitory polypeptide and vasopressin(2) receptor proteins in tumorous zona fasciculata tissue may play a role in the pathogenesis of canine cortisol-secreting adrenocortical tumors
Title: Expression of receptors for luteinizing hormone, gastric-inhibitory polypeptide, and vasopressin in normal adrenal glands and cortisol-secreting adrenocortical tumors in dogs.

X-linked nephrogenic diabetes insipidus is caused by mutations in the gene encoding the vasopressin V2 receptor
Title: Characterization of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus in a polarized cell model.

a C-terminal region of the V2R important for calmodulin interaction is also important in modulation of V2R elevation of intracellular Ca2
Title: Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium.

The following AVPR2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the AVPR2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe31933	NM_001003177.1 Latest version!	Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OCe31933	XM_005640983.3 Latest version!	Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
OCe31933	XM_022415491.1 Latest version!	Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
View Old Accession Versions >>
OCe31933	XM_005640983.2	Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

AVPR2 ( NM_001003177.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003177.1 Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), mRNA.

Price & Availability↑

CloneID	OCe31933
Clone ID Related Accession (Same CDS sequence)	NM_001003177.1 , XM_022415491.1 , XM_005640983.2 , XM_005640983.3
Accession Version	NM_001003177.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-15
Organism	Canis lupus familiaris(dog)
Product	vasopressin V2 receptor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Y18136.2. ##Evidence-Data-START## Transcript exon combination :: Y18136.2 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547739, SAMN00013513 [ECO:0000348] ##Evidence-Data-END##

ATGCTCCTGG CATCCACCAC CTCGGCTGTG CCCCGGACCC TCTCTCCACC TACTCCAGCT 
GGCAACGGCA GCAGGGAGCT GCTGGACACC CGGGACCCGC TGCTTGTCCA GGCCGAGCTA 
GCCCTGCTCT CCACGGTCTT CGTGGCTGTG GCCCTGAGCA ACGGCCTGGT GCTGGGGGCC 
CTGGCGCGCC GGGTCCGGCG GGGTCGCTGG GCACCCATGC ACGTCTTCAT TGGCCACTTG 
TGCCTGGCCG ACCTGGCTGT GGCTCTGTTC CAAGTACTGC CCCAGCTGGC GTGGGATGCC 
ACGGACCGCT TCCGTGGGCC TGATGCCCTG TGCCGGGCAG TCAAGTACCT GCAGATGGTG 
GGCATGTATG CCTCCTCCTA CATGATCCTG GCCATGACGC TGGACCGCCA CCGCGCCATC 
TGCCGCCCCA TGCTGGCATA CCGCCACGGA GGTGGAGCTC GCTGGAACCG GCCGGTGCTG 
GTGGCCTGGG CCTTCTCGCT CATTCTCAGC CTGCCCCAGC TCTTCATCTT TGCCCAGCGT 
GACGTGGGAA ATGGCAGTGG GGTCCTTGAC TGCTGGGCCC ACTTCGCTGA GCCCTGGGGC 
CTCCGAGCCT ATGTCACCTG GATCGCCCTA ATGGTCTTTG TGGCACCTGC CCTGGGCATC 
GCGGCCTGCC AGGTGCTCAT CTTCCGGGAG ATTCACTCCA GCCTGGTGCC GGGGCCAGCA 
GAGAGGGCTG GGGGGTGCCG TGGAGGGCAC CGGACCGGCA GCCCCAGCGA GGGGGCCCGG 
GTGTCCGCAG CCATGGCCAA GACGGTGAGG ATGACGCTGG TCATTGTGAT CGTCTACGTG 
TTGTGCTGGG CGCCCTTCTT CCTCGTGCAG CTGTGGGCAG CGTGGGACCC GCAGGCGCCC 
CTGGAAGGGG CCCCCTTCGT GCTGCTTATG TTGCTGGCCA GCCTCAACAG CTGCACCAAC 
CCCTGGATCT ACGCCTTCTT CAGCAGCAGC GTCTCCTCCG AGCTGCGCAG CCTGTTCTGC 
TGGGCCCGGA GTCGGGCCCC ACCCAGCCTG GGGCCCCAAG AGGAGTCCTG CGCCACGGCC 
AGCTCCTTCC TGGCCAAGGA CACTTCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003177.1
CDS	34..1146
Translation	MLLASTTSAVPRTLSPPTPAGNGSRELLDTRDPLLVQAELALLSTVFVAVALSNGLVLGALARRVRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLILSLPQLFIFAQRDVGNGSGVLDCWAHFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHSSLVPGPAERAGGCRGGHRTGSPSEGARVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPQAPLEGAPFVLLMLLASLNSCTNPWIYAFFSSSVSSELRSLFCWARSRAPPSLGPQEESCATASSFLAKDTSS

Target ORF information:

RefSeq Version	NM_001003177.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003177.1

ORF Insert Sequence:

ATGCTCCTGG CATCCACCAC CTCGGCTGTG CCCCGGACCC TCTCTCCACC TACTCCAGCT 
GGCAACGGCA GCAGGGAGCT GCTGGACACC CGGGACCCGC TGCTTGTCCA GGCCGAGCTA 
GCCCTGCTCT CCACGGTCTT CGTGGCTGTG GCCCTGAGCA ACGGCCTGGT GCTGGGGGCC 
CTGGCGCGCC GGGTCCGGCG GGGTCGCTGG GCACCCATGC ACGTCTTCAT TGGCCACTTG 
TGCCTGGCCG ACCTGGCTGT GGCTCTGTTC CAAGTACTGC CCCAGCTGGC GTGGGATGCC 
ACGGACCGCT TCCGTGGGCC TGATGCCCTG TGCCGGGCAG TCAAGTACCT GCAGATGGTG 
GGCATGTATG CCTCCTCCTA CATGATCCTG GCCATGACGC TGGACCGCCA CCGCGCCATC 
TGCCGCCCCA TGCTGGCATA CCGCCACGGA GGTGGAGCTC GCTGGAACCG GCCGGTGCTG 
GTGGCCTGGG CCTTCTCGCT CATTCTCAGC CTGCCCCAGC TCTTCATCTT TGCCCAGCGT 
GACGTGGGAA ATGGCAGTGG GGTCCTTGAC TGCTGGGCCC ACTTCGCTGA GCCCTGGGGC 
CTCCGAGCCT ATGTCACCTG GATCGCCCTA ATGGTCTTTG TGGCACCTGC CCTGGGCATC 
GCGGCCTGCC AGGTGCTCAT CTTCCGGGAG ATTCACTCCA GCCTGGTGCC GGGGCCAGCA 
GAGAGGGCTG GGGGGTGCCG TGGAGGGCAC CGGACCGGCA GCCCCAGCGA GGGGGCCCGG 
GTGTCCGCAG CCATGGCCAA GACGGTGAGG ATGACGCTGG TCATTGTGAT CGTCTACGTG 
TTGTGCTGGG CGCCCTTCTT CCTCGTGCAG CTGTGGGCAG CGTGGGACCC GCAGGCGCCC 
CTGGAAGGGG CCCCCTTCGT GCTGCTTATG TTGCTGGCCA GCCTCAACAG CTGCACCAAC 
CCCTGGATCT ACGCCTTCTT CAGCAGCAGC GTCTCCTCCG AGCTGCGCAG CCTGTTCTGC 
TGGGCCCGGA GTCGGGCCCC ACCCAGCCTG GGGCCCCAAG AGGAGTCCTG CGCCACGGCC 
AGCTCCTTCC TGGCCAAGGA CACTTCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AVPR2 ( XM_022415491.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_022271199.1 Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X2, mRNA.

Price & Availability↑

CloneID	OCe31933
Clone ID Related Accession (Same CDS sequence)	NM_001003177.1 , XM_022415491.1 , XM_005640983.2 , XM_005640983.3
Accession Version	XM_022415491.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	vasopressin V2 receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006621.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCCTGG CATCCACCAC CTCGGCTGTG CCCCGGACCC TCTCTCCACC TACTCCAGCT 
GGCAACGGCA GCAGGGAGCT GCTGGACACC CGGGACCCGC TGCTTGTCCA GGCCGAGCTA 
GCCCTGCTCT CCACGGTCTT CGTGGCTGTG GCCCTGAGCA ACGGCCTGGT GCTGGGGGCC 
CTGGCGCGCC GGGTCCGGCG GGGTCGCTGG GCACCCATGC ACGTCTTCAT TGGCCACTTG 
TGCCTGGCCG ACCTGGCTGT GGCTCTGTTC CAAGTACTGC CCCAGCTGGC GTGGGATGCC 
ACGGACCGCT TCCGTGGGCC TGATGCCCTG TGCCGGGCAG TCAAGTACCT GCAGATGGTG 
GGCATGTATG CCTCCTCCTA CATGATCCTG GCCATGACGC TGGACCGCCA CCGCGCCATC 
TGCCGCCCCA TGCTGGCATA CCGCCACGGA GGTGGAGCTC GCTGGAACCG GCCGGTGCTG 
GTGGCCTGGG CCTTCTCGCT CATTCTCAGC CTGCCCCAGC TCTTCATCTT TGCCCAGCGT 
GACGTGGGAA ATGGCAGTGG GGTCCTTGAC TGCTGGGCCC ACTTCGCTGA GCCCTGGGGC 
CTCCGAGCCT ATGTCACCTG GATCGCCCTA ATGGTCTTTG TGGCACCTGC CCTGGGCATC 
GCGGCCTGCC AGGTGCTCAT CTTCCGGGAG ATTCACTCCA GCCTGGTGCC GGGGCCAGCA 
GAGAGGGCTG GGGGGTGCCG TGGAGGGCAC CGGACCGGCA GCCCCAGCGA GGGGGCCCGG 
GTGTCCGCAG CCATGGCCAA GACGGTGAGG ATGACGCTGG TCATTGTGAT CGTCTACGTG 
TTGTGCTGGG CGCCCTTCTT CCTCGTGCAG CTGTGGGCAG CGTGGGACCC GCAGGCGCCC 
CTGGAAGGGG CCCCCTTCGT GCTGCTTATG TTGCTGGCCA GCCTCAACAG CTGCACCAAC 
CCCTGGATCT ACGCCTTCTT CAGCAGCAGC GTCTCCTCCG AGCTGCGCAG CCTGTTCTGC 
TGGGCCCGGA GTCGGGCCCC ACCCAGCCTG GGGCCCCAAG AGGAGTCCTG CGCCACGGCC 
AGCTCCTTCC TGGCCAAGGA CACTTCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_022271199.1
CDS	431..1543
Translation	MLLASTTSAVPRTLSPPTPAGNGSRELLDTRDPLLVQAELALLSTVFVAVALSNGLVLGALARRVRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLILSLPQLFIFAQRDVGNGSGVLDCWAHFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHSSLVPGPAERAGGCRGGHRTGSPSEGARVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPQAPLEGAPFVLLMLLASLNSCTNPWIYAFFSSSVSSELRSLFCWARSRAPPSLGPQEESCATASSFLAKDTSS

Target ORF information:

RefSeq Version	XM_022415491.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_022415491.1

ORF Insert Sequence:

ATGCTCCTGG CATCCACCAC CTCGGCTGTG CCCCGGACCC TCTCTCCACC TACTCCAGCT 
GGCAACGGCA GCAGGGAGCT GCTGGACACC CGGGACCCGC TGCTTGTCCA GGCCGAGCTA 
GCCCTGCTCT CCACGGTCTT CGTGGCTGTG GCCCTGAGCA ACGGCCTGGT GCTGGGGGCC 
CTGGCGCGCC GGGTCCGGCG GGGTCGCTGG GCACCCATGC ACGTCTTCAT TGGCCACTTG 
TGCCTGGCCG ACCTGGCTGT GGCTCTGTTC CAAGTACTGC CCCAGCTGGC GTGGGATGCC 
ACGGACCGCT TCCGTGGGCC TGATGCCCTG TGCCGGGCAG TCAAGTACCT GCAGATGGTG 
GGCATGTATG CCTCCTCCTA CATGATCCTG GCCATGACGC TGGACCGCCA CCGCGCCATC 
TGCCGCCCCA TGCTGGCATA CCGCCACGGA GGTGGAGCTC GCTGGAACCG GCCGGTGCTG 
GTGGCCTGGG CCTTCTCGCT CATTCTCAGC CTGCCCCAGC TCTTCATCTT TGCCCAGCGT 
GACGTGGGAA ATGGCAGTGG GGTCCTTGAC TGCTGGGCCC ACTTCGCTGA GCCCTGGGGC 
CTCCGAGCCT ATGTCACCTG GATCGCCCTA ATGGTCTTTG TGGCACCTGC CCTGGGCATC 
GCGGCCTGCC AGGTGCTCAT CTTCCGGGAG ATTCACTCCA GCCTGGTGCC GGGGCCAGCA 
GAGAGGGCTG GGGGGTGCCG TGGAGGGCAC CGGACCGGCA GCCCCAGCGA GGGGGCCCGG 
GTGTCCGCAG CCATGGCCAA GACGGTGAGG ATGACGCTGG TCATTGTGAT CGTCTACGTG 
TTGTGCTGGG CGCCCTTCTT CCTCGTGCAG CTGTGGGCAG CGTGGGACCC GCAGGCGCCC 
CTGGAAGGGG CCCCCTTCGT GCTGCTTATG TTGCTGGCCA GCCTCAACAG CTGCACCAAC 
CCCTGGATCT ACGCCTTCTT CAGCAGCAGC GTCTCCTCCG AGCTGCGCAG CCTGTTCTGC 
TGGGCCCGGA GTCGGGCCCC ACCCAGCCTG GGGCCCCAAG AGGAGTCCTG CGCCACGGCC 
AGCTCCTTCC TGGCCAAGGA CACTTCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AVPR2 ( XM_005640983.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005641040.1 Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe31933
Clone ID Related Accession (Same CDS sequence)	NM_001003177.1 , XM_022415491.1 , XM_005640983.2 , XM_005640983.3
Accession Version	XM_005640983.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	vasopressin V2 receptor isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726126.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005640983.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCCTGG CATCCACCAC CTCGGCTGTG CCCCGGACCC TCTCTCCACC TACTCCAGCT 
GGCAACGGCA GCAGGGAGCT GCTGGACACC CGGGACCCGC TGCTTGTCCA GGCCGAGCTA 
GCCCTGCTCT CCACGGTCTT CGTGGCTGTG GCCCTGAGCA ACGGCCTGGT GCTGGGGGCC 
CTGGCGCGCC GGGTCCGGCG GGGTCGCTGG GCACCCATGC ACGTCTTCAT TGGCCACTTG 
TGCCTGGCCG ACCTGGCTGT GGCTCTGTTC CAAGTACTGC CCCAGCTGGC GTGGGATGCC 
ACGGACCGCT TCCGTGGGCC TGATGCCCTG TGCCGGGCAG TCAAGTACCT GCAGATGGTG 
GGCATGTATG CCTCCTCCTA CATGATCCTG GCCATGACGC TGGACCGCCA CCGCGCCATC 
TGCCGCCCCA TGCTGGCATA CCGCCACGGA GGTGGAGCTC GCTGGAACCG GCCGGTGCTG 
GTGGCCTGGG CCTTCTCGCT CATTCTCAGC CTGCCCCAGC TCTTCATCTT TGCCCAGCGT 
GACGTGGGAA ATGGCAGTGG GGTCCTTGAC TGCTGGGCCC ACTTCGCTGA GCCCTGGGGC 
CTCCGAGCCT ATGTCACCTG GATCGCCCTA ATGGTCTTTG TGGCACCTGC CCTGGGCATC 
GCGGCCTGCC AGGTGCTCAT CTTCCGGGAG ATTCACTCCA GCCTGGTGCC GGGGCCAGCA 
GAGAGGGCTG GGGGGTGCCG TGGAGGGCAC CGGACCGGCA GCCCCAGCGA GGGGGCCCGG 
GTGTCCGCAG CCATGGCCAA GACGGTGAGG ATGACGCTGG TCATTGTGAT CGTCTACGTG 
TTGTGCTGGG CGCCCTTCTT CCTCGTGCAG CTGTGGGCAG CGTGGGACCC GCAGGCGCCC 
CTGGAAGGGG CCCCCTTCGT GCTGCTTATG TTGCTGGCCA GCCTCAACAG CTGCACCAAC 
CCCTGGATCT ACGCCTTCTT CAGCAGCAGC GTCTCCTCCG AGCTGCGCAG CCTGTTCTGC 
TGGGCCCGGA GTCGGGCCCC ACCCAGCCTG GGGCCCCAAG AGGAGTCCTG CGCCACGGCC 
AGCTCCTTCC TGGCCAAGGA CACTTCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005641040.1
CDS	138..1250
Translation	MLLASTTSAVPRTLSPPTPAGNGSRELLDTRDPLLVQAELALLSTVFVAVALSNGLVLGALARRVRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLILSLPQLFIFAQRDVGNGSGVLDCWAHFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHSSLVPGPAERAGGCRGGHRTGSPSEGARVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPQAPLEGAPFVLLMLLASLNSCTNPWIYAFFSSSVSSELRSLFCWARSRAPPSLGPQEESCATASSFLAKDTSS

Target ORF information:

RefSeq Version	XM_005640983.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005640983.2

ORF Insert Sequence:

ATGCTCCTGG CATCCACCAC CTCGGCTGTG CCCCGGACCC TCTCTCCACC TACTCCAGCT 
GGCAACGGCA GCAGGGAGCT GCTGGACACC CGGGACCCGC TGCTTGTCCA GGCCGAGCTA 
GCCCTGCTCT CCACGGTCTT CGTGGCTGTG GCCCTGAGCA ACGGCCTGGT GCTGGGGGCC 
CTGGCGCGCC GGGTCCGGCG GGGTCGCTGG GCACCCATGC ACGTCTTCAT TGGCCACTTG 
TGCCTGGCCG ACCTGGCTGT GGCTCTGTTC CAAGTACTGC CCCAGCTGGC GTGGGATGCC 
ACGGACCGCT TCCGTGGGCC TGATGCCCTG TGCCGGGCAG TCAAGTACCT GCAGATGGTG 
GGCATGTATG CCTCCTCCTA CATGATCCTG GCCATGACGC TGGACCGCCA CCGCGCCATC 
TGCCGCCCCA TGCTGGCATA CCGCCACGGA GGTGGAGCTC GCTGGAACCG GCCGGTGCTG 
GTGGCCTGGG CCTTCTCGCT CATTCTCAGC CTGCCCCAGC TCTTCATCTT TGCCCAGCGT 
GACGTGGGAA ATGGCAGTGG GGTCCTTGAC TGCTGGGCCC ACTTCGCTGA GCCCTGGGGC 
CTCCGAGCCT ATGTCACCTG GATCGCCCTA ATGGTCTTTG TGGCACCTGC CCTGGGCATC 
GCGGCCTGCC AGGTGCTCAT CTTCCGGGAG ATTCACTCCA GCCTGGTGCC GGGGCCAGCA 
GAGAGGGCTG GGGGGTGCCG TGGAGGGCAC CGGACCGGCA GCCCCAGCGA GGGGGCCCGG 
GTGTCCGCAG CCATGGCCAA GACGGTGAGG ATGACGCTGG TCATTGTGAT CGTCTACGTG 
TTGTGCTGGG CGCCCTTCTT CCTCGTGCAG CTGTGGGCAG CGTGGGACCC GCAGGCGCCC 
CTGGAAGGGG CCCCCTTCGT GCTGCTTATG TTGCTGGCCA GCCTCAACAG CTGCACCAAC 
CCCTGGATCT ACGCCTTCTT CAGCAGCAGC GTCTCCTCCG AGCTGCGCAG CCTGTTCTGC 
TGGGCCCGGA GTCGGGCCCC ACCCAGCCTG GGGCCCCAAG AGGAGTCCTG CGCCACGGCC 
AGCTCCTTCC TGGCCAAGGA CACTTCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

AVPR2 ( XM_005640983.3 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005641040.1 Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe31933
Clone ID Related Accession (Same CDS sequence)	NM_001003177.1 , XM_022415491.1 , XM_005640983.2 , XM_005640983.3
Accession Version	XM_005640983.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1113bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	vasopressin V2 receptor isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006621.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005640983.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCTCCTGG CATCCACCAC CTCGGCTGTG CCCCGGACCC TCTCTCCACC TACTCCAGCT 
GGCAACGGCA GCAGGGAGCT GCTGGACACC CGGGACCCGC TGCTTGTCCA GGCCGAGCTA 
GCCCTGCTCT CCACGGTCTT CGTGGCTGTG GCCCTGAGCA ACGGCCTGGT GCTGGGGGCC 
CTGGCGCGCC GGGTCCGGCG GGGTCGCTGG GCACCCATGC ACGTCTTCAT TGGCCACTTG 
TGCCTGGCCG ACCTGGCTGT GGCTCTGTTC CAAGTACTGC CCCAGCTGGC GTGGGATGCC 
ACGGACCGCT TCCGTGGGCC TGATGCCCTG TGCCGGGCAG TCAAGTACCT GCAGATGGTG 
GGCATGTATG CCTCCTCCTA CATGATCCTG GCCATGACGC TGGACCGCCA CCGCGCCATC 
TGCCGCCCCA TGCTGGCATA CCGCCACGGA GGTGGAGCTC GCTGGAACCG GCCGGTGCTG 
GTGGCCTGGG CCTTCTCGCT CATTCTCAGC CTGCCCCAGC TCTTCATCTT TGCCCAGCGT 
GACGTGGGAA ATGGCAGTGG GGTCCTTGAC TGCTGGGCCC ACTTCGCTGA GCCCTGGGGC 
CTCCGAGCCT ATGTCACCTG GATCGCCCTA ATGGTCTTTG TGGCACCTGC CCTGGGCATC 
GCGGCCTGCC AGGTGCTCAT CTTCCGGGAG ATTCACTCCA GCCTGGTGCC GGGGCCAGCA 
GAGAGGGCTG GGGGGTGCCG TGGAGGGCAC CGGACCGGCA GCCCCAGCGA GGGGGCCCGG 
GTGTCCGCAG CCATGGCCAA GACGGTGAGG ATGACGCTGG TCATTGTGAT CGTCTACGTG 
TTGTGCTGGG CGCCCTTCTT CCTCGTGCAG CTGTGGGCAG CGTGGGACCC GCAGGCGCCC 
CTGGAAGGGG CCCCCTTCGT GCTGCTTATG TTGCTGGCCA GCCTCAACAG CTGCACCAAC 
CCCTGGATCT ACGCCTTCTT CAGCAGCAGC GTCTCCTCCG AGCTGCGCAG CCTGTTCTGC 
TGGGCCCGGA GTCGGGCCCC ACCCAGCCTG GGGCCCCAAG AGGAGTCCTG CGCCACGGCC 
AGCTCCTTCC TGGCCAAGGA CACTTCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005641040.1
CDS	142..1254
Translation	MLLASTTSAVPRTLSPPTPAGNGSRELLDTRDPLLVQAELALLSTVFVAVALSNGLVLGALARRVRRGRWAPMHVFIGHLCLADLAVALFQVLPQLAWDATDRFRGPDALCRAVKYLQMVGMYASSYMILAMTLDRHRAICRPMLAYRHGGGARWNRPVLVAWAFSLILSLPQLFIFAQRDVGNGSGVLDCWAHFAEPWGLRAYVTWIALMVFVAPALGIAACQVLIFREIHSSLVPGPAERAGGCRGGHRTGSPSEGARVSAAMAKTVRMTLVIVIVYVLCWAPFFLVQLWAAWDPQAPLEGAPFVLLMLLASLNSCTNPWIYAFFSSSVSSELRSLFCWARSRAPPSLGPQEESCATASSFLAKDTSS

Target ORF information:

RefSeq Version	XM_005640983.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris arginine vasopressin receptor 2 (AVPR2), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005640983.3

ORF Insert Sequence:

ATGCTCCTGG CATCCACCAC CTCGGCTGTG CCCCGGACCC TCTCTCCACC TACTCCAGCT 
GGCAACGGCA GCAGGGAGCT GCTGGACACC CGGGACCCGC TGCTTGTCCA GGCCGAGCTA 
GCCCTGCTCT CCACGGTCTT CGTGGCTGTG GCCCTGAGCA ACGGCCTGGT GCTGGGGGCC 
CTGGCGCGCC GGGTCCGGCG GGGTCGCTGG GCACCCATGC ACGTCTTCAT TGGCCACTTG 
TGCCTGGCCG ACCTGGCTGT GGCTCTGTTC CAAGTACTGC CCCAGCTGGC GTGGGATGCC 
ACGGACCGCT TCCGTGGGCC TGATGCCCTG TGCCGGGCAG TCAAGTACCT GCAGATGGTG 
GGCATGTATG CCTCCTCCTA CATGATCCTG GCCATGACGC TGGACCGCCA CCGCGCCATC 
TGCCGCCCCA TGCTGGCATA CCGCCACGGA GGTGGAGCTC GCTGGAACCG GCCGGTGCTG 
GTGGCCTGGG CCTTCTCGCT CATTCTCAGC CTGCCCCAGC TCTTCATCTT TGCCCAGCGT 
GACGTGGGAA ATGGCAGTGG GGTCCTTGAC TGCTGGGCCC ACTTCGCTGA GCCCTGGGGC 
CTCCGAGCCT ATGTCACCTG GATCGCCCTA ATGGTCTTTG TGGCACCTGC CCTGGGCATC 
GCGGCCTGCC AGGTGCTCAT CTTCCGGGAG ATTCACTCCA GCCTGGTGCC GGGGCCAGCA 
GAGAGGGCTG GGGGGTGCCG TGGAGGGCAC CGGACCGGCA GCCCCAGCGA GGGGGCCCGG 
GTGTCCGCAG CCATGGCCAA GACGGTGAGG ATGACGCTGG TCATTGTGAT CGTCTACGTG 
TTGTGCTGGG CGCCCTTCTT CCTCGTGCAG CTGTGGGCAG CGTGGGACCC GCAGGCGCCC 
CTGGAAGGGG CCCCCTTCGT GCTGCTTATG TTGCTGGCCA GCCTCAACAG CTGCACCAAC 
CCCTGGATCT ACGCCTTCTT CAGCAGCAGC GTCTCCTCCG AGCTGCGCAG CCTGTTCTGC 
TGGGCCCGGA GTCGGGCCCC ACCCAGCCTG GGGCCCCAAG AGGAGTCCTG CGCCACGGCC 
AGCTCCTTCC TGGCCAAGGA CACTTCCTCC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Noncanonical control of vasopressin receptor type 2 signaling by retromer and arrestin.
The Journal of biological chemistry288(39)27849-60(2013 Sep)
Feinstein TN,Yui N,Webber MJ,Wehbi VL,Stevenson HP,King JD Jr,Hallows KR,Brown D,Bouley R,Vilardaga JP

Expression of receptors for luteinizing hormone, gastric-inhibitory polypeptide, and vasopressin in normal adrenal glands and cortisol-secreting adrenocortical tumors in dogs.
Domestic animal endocrinology39(1)63-75(2010 Jul)
Galac S,Kars VJ,Klarenbeek S,Teerds KJ,Mol JA,Kooistra HS

Involvement of the V2 vasopressin receptor in adaptation to limited water supply.
PloS one4(5)e5573(2009)
B?selt I,R?mpler H,Hermsdorf T,Thor D,Busch W,Schulz A,Sch?neberg T

Characterization of vasopressin V2 receptor mutants in nephrogenic diabetes insipidus in a polarized cell model.
American journal of physiology. Renal physiology289(2)F265-72(2005 Aug)
Robben JH,Knoers NV,Deen PM

Calmodulin interacts with the V2 vasopressin receptor: elimination of binding to the C terminus also eliminates arginine vasopressin-stimulated elevation of intracellular calcium.
The Journal of biological chemistry279(45)46969-80(2004 Nov)
Nickols HH,Shah VN,Chazin WJ,Limbird LE