RAB1A cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	RAB1A
Entrez Gene ID	403774
Full Name	RAB1A, member RAS oncogene family
Synonyms	RAB1
General protein information	Preferred Names RAB1A, member RAS oncogene family Names ras-related protein Rab-1A
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003153.1	NP_001003153.1	ras-related protein Rab-1A

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	RAB1A	XP_530454.3
Danio rerio (zebrafish)	rab1a	NP_001007162.1
Saccharomyces cerevisiae (baker's yeast)	YPT1	NP_116615.1
Kluyveromyces lactis	KLLA0D05313g	XP_453297.1
Neurospora crassa	NCU08477	XP_963146.2
Xenopus tropicalis (tropical clawed frog)	rab1a	NP_001004787.1
Caenorhabditis elegans (roundworm)	rab-1	NP_503397.1
Eremothecium gossypii	AGOS_ABR220W	NP_983169.1
Arabidopsis thaliana (thale cress)	RA-5	NP_171715.1
Oryza sativa (rice)	Os01g0558600	NP_001043336.1
Homo sapiens (human)	RAB1A	NP_004152.1
Gallus gallus (chicken)	RAB1A	NP_001257591.1
Drosophila melanogaster (fruit fly)	Rab1	NP_732610.1
Schizosaccharomyces pombe (fission yeast)	ypt1	NP_596205.1
	RAB1A	XP_001090072.1
Canis lupus familiaris (dog)	RAB1A	NP_001003153.1
Magnaporthe oryzae (rice blast fungus)	MGG_06962	XP_003709708.1
Mus musculus (house mouse)	Rab1	NP_033022.1
Rattus norvegicus (Norway rat)	Rab1a	NP_112352.2
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP004146	XP_313029.4

Gene Ontology
Bibliography

Related articles in PubMed

Rab1 recruits WHAMM during membrane remodeling but limits actin nucleation.
Russo AJ, Mathiowetz AJ, Hong S, Welch MD, Campellone KG
Molecular biology of the cell27(6)967-78(2016 Mar)

Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis.
Cao Z, Li C, Higginbotham JN, Franklin JL, Tabb DL, Graves-Deal R, Hill S, Cheek K, Jerome WG, Lapierre LA, Goldenring JR, Ham AJ, Coffey RJ
Molecular & cellular proteomics : MCP7(9)1651-67(2008 Sep)

Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitor.
Chen CZ, Calero M, DeRegis CJ, Heidtman M, Barlowe C, Collins RN
Genetics168(4)1827-41(2004 Dec)

Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes.
Alexandrov K, Horiuchi H, Steele-Mortimer O, Seabra MC, Zerial M
The EMBO journal13(22)5262-73(1994 Nov)

Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.
Chavrier P, Vingron M, Sander C, Simons K, Zerial M
Molecular and cellular biology10(12)6578-85(1990 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The ability of Rab1 to regulate WHAMM and the Arp2/3 complex represents a distinct strategy for membrane remodeling in which a Rab G-protein recruits the actin nucleation machinery but dampens its activity.
Title: Rab1 recruits WHAMM during membrane remodeling but limits actin nucleation.

The following RAB1A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the RAB1A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe00149	NM_001003153.1 Latest version!	Canis lupus familiaris RAB1A, member RAS oncogene family (RAB1A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$174.30 $249.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

RAB1A ( NM_001003153.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003153.1 Canis lupus familiaris RAB1A, member RAS oncogene family (RAB1A), mRNA.

Price & Availability↑

CloneID	OCe00149
Clone ID Related Accession (Same CDS sequence)	NM_001003153.1
Accession Version	NM_001003153.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 618bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-09-20
Organism	Canis lupus familiaris(dog)
Product	ras-related protein Rab-1A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from X56384.1. On Jan 12, 2005 this sequence version replaced XM_531849.1. ##Evidence-Data-START## Transcript exon combination :: X56384.1, DN392048.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END##

ATGTCCAGCA TGAATCCCGA ATATGATTAT TTATTCAAGT TACTTCTGAT TGGCGACTCT 
GGGGTTGGAA AGTCTTGCCT CCTTCTTAGG TTTGCAGATG ATACATATAC AGAAAGCTAC 
ATCAGCACAA TTGGTGTGGA TTTCAAAATA AGAACTATAG AGTTAGATGG GAAAACAATC 
AAGCTTCAAA TATGGGACAC AGCAGGCCAA GAAAGATTTC GAACAATCAC CTCCAGTTAT 
TACAGAGGAG CCCATGGCAT CATAGTTGTG TATGACGTGA CAGATCAGGA GTCCTTCAAT 
AATGTTAAAC AGTGGCTGCA GGAAATAGAC CGTTATGCCA GTGAAAACGT CAACAAGTTG 
TTGGTAGGGA ACAAATGCGA TCTGACCACA AAGAAAGTAG TAGACTACAC AACAGCAAAG 
GAATTTGCGG ATTCCCTTGG AATTCCATTT TTGGAAACCA GTGCTAAGAA CGCAACGAAT 
GTAGAACAGT CTTTCATGAC GATGGCAGCT GAGATTAAAA AGCGAATGGG TCCTGGAGCA 
ACAGCTGGTG GTGCAGAGAA GTCCAATGTG AAAATTCAGA GCACTCCGGT CAAGCAGTCA 
GGTGGAGGTT GCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003153.1
CDS	149..766
Translation	MSSMNPEYDYLFKLLLIGDSGVGKSCLLLRFADDTYTESYISTIGVDFKIRTIELDGKTIKLQIWDTAGQERFRTITSSYYRGAHGIIVVYDVTDQESFNNVKQWLQEIDRYASENVNKLLVGNKCDLTTKKVVDYTTAKEFADSLGIPFLETSAKNATNVEQSFMTMAAEIKKRMGPGATAGGAEKSNVKIQSTPVKQSGGGCC

Target ORF information:

RefSeq Version	NM_001003153.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris RAB1A, member RAS oncogene family (RAB1A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003153.1

ORF Insert Sequence:

ATGTCCAGCA TGAATCCCGA ATATGATTAT TTATTCAAGT TACTTCTGAT TGGCGACTCT 
GGGGTTGGAA AGTCTTGCCT CCTTCTTAGG TTTGCAGATG ATACATATAC AGAAAGCTAC 
ATCAGCACAA TTGGTGTGGA TTTCAAAATA AGAACTATAG AGTTAGATGG GAAAACAATC 
AAGCTTCAAA TATGGGACAC AGCAGGCCAA GAAAGATTTC GAACAATCAC CTCCAGTTAT 
TACAGAGGAG CCCATGGCAT CATAGTTGTG TATGACGTGA CAGATCAGGA GTCCTTCAAT 
AATGTTAAAC AGTGGCTGCA GGAAATAGAC CGTTATGCCA GTGAAAACGT CAACAAGTTG 
TTGGTAGGGA ACAAATGCGA TCTGACCACA AAGAAAGTAG TAGACTACAC AACAGCAAAG 
GAATTTGCGG ATTCCCTTGG AATTCCATTT TTGGAAACCA GTGCTAAGAA CGCAACGAAT 
GTAGAACAGT CTTTCATGAC GATGGCAGCT GAGATTAAAA AGCGAATGGG TCCTGGAGCA 
ACAGCTGGTG GTGCAGAGAA GTCCAATGTG AAAATTCAGA GCACTCCGGT CAAGCAGTCA 
GGTGGAGGTT GCTGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Rab1 recruits WHAMM during membrane remodeling but limits actin nucleation.
Molecular biology of the cell27(6)967-78(2016 Mar)
Russo AJ,Mathiowetz AJ,Hong S,Welch MD,Campellone KG

Use of fluorescence-activated vesicle sorting for isolation of Naked2-associated, basolaterally targeted exocytic vesicles for proteomics analysis.
Molecular & cellular proteomics : MCP7(9)1651-67(2008 Sep)
Cao Z,Li C,Higginbotham JN,Franklin JL,Tabb DL,Graves-Deal R,Hill S,Cheek K,Jerome WG,Lapierre LA,Goldenring JR,Ham AJ,Coffey RJ

Genetic analysis of yeast Yip1p function reveals a requirement for Golgi-localized rab proteins and rab-Guanine nucleotide dissociation inhibitor.
Genetics168(4)1827-41(2004 Dec)
Chen CZ,Calero M,DeRegis CJ,Heidtman M,Barlowe C,Collins RN

Rab escort protein-1 is a multifunctional protein that accompanies newly prenylated rab proteins to their target membranes.
The EMBO journal13(22)5262-73(1994 Nov)
Alexandrov K,Horiuchi H,Steele-Mortimer O,Seabra MC,Zerial M

Molecular cloning of YPT1/SEC4-related cDNAs from an epithelial cell line.
Molecular and cellular biology10(12)6578-85(1990 Dec)
Chavrier P,Vingron M,Sander C,Simons K,Zerial M