SLC2A4 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	SLC2A4
Entrez Gene ID	403673
Full Name	solute carrier family 2 member 4
Synonyms	GLUT4
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
XM_005619478.2	XP_005619535.2	solute carrier family 2, facilitated glucose transporter member 4 isoform X1
NM_001159327.1	NP_001152799.1	solute carrier family 2, facilitated glucose transporter member 4
XM_005619478.3	XP_005619535.3	solute carrier family 2, facilitated glucose transporter member 4 isoform X1

Pathways from BioSystems

Homologies

Bos taurus (cattle)	SLC2A4	NP_777029.1
Rattus norvegicus (Norway rat)	Slc2a4	NP_036883.1
Pan troglodytes (chimpanzee)	SLC2A4	XP_001169794.1
	SLC2A4	XP_001107391.1
Mus musculus (house mouse)	Slc2a4	NP_033230.2
Homo sapiens (human)	SLC2A4	NP_001033.1
Canis lupus familiaris (dog)	SLC2A4	NP_001152799.1

Gene Ontology
Bibliography

Related articles in PubMed

Conditioning causes an increase in glucose transporter-4 levels in mononuclear cells in sled dogs.
Schnurr TM, Reynolds AJ, Gustafson SJ, Duffy LK, Dunlap KL
The international journal of biochemistry & cell biology55227-31(2014 Oct)

Intervention of rosiglitazone on myocardium Glut-4 mRNA expression during ischemia-reperfusion injury in cardio-pulmonary bypass in dogs.
Liu B, Liang G, Xu G, Liu D, Cai Q, Gao Z
Molecular and cellular biochemistry373(1-2)279-84(2013 Jan)

Chronic heart failure selectively induces regional heterogeneity of insulin-responsive glucose transporters.
Ware B, Bevier M, Nishijima Y, Rogers S, Carnes CA, Lacombe VA
American journal of physiology. Regulatory, integrative and comparative physiology301(5)R1300-6(2011 Nov)

Cardiac glucose uptake and suppressed expression/translocation of myocardium glucose transport-4 in dogs undergoing ischemia-reperfusion.
Liang GY, Cai QY, Niu YM, Zheng H, Gao ZY, Liu DX, Xu G
Experimental biology and medicine (Maywood, N.J.)233(9)1142-8(2008 Sep)

A method for the large-scale cloning of nuclear proteins and nuclear targeting sequences on a functional basis.
Pichon B, Mercan D, Pouillon V, Christophe-Hobertus C, Christophe D
Analytical biochemistry284(2)231-9(2000 Sep)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Results indicate that the state of conditioning had a significant effect on the glucose transporter-4 protein (GLUT4) expression at the surface of mononuclear cells.
Title: Conditioning causes an increase in glucose transporter-4 levels in mononuclear cells in sled dogs.

Damage of cardiac function during cardiopulomnary bypass are mostly associated with lower expression of Glut-4 mRNA.
Title: Intervention of rosiglitazone on myocardium Glut-4 mRNA expression during ischemia-reperfusion injury in cardio-pulmonary bypass in dogs.

Chronic heart failure selectively induces regional heterogeneity of insulin-responsive glucose transporters, GLUT4/12.
Title: Chronic heart failure selectively induces regional heterogeneity of insulin-responsive glucose transporters.

Suppressed translocation of GLUT-4 was also evident in dogs receiving 30-min ischemia
Title: Cardiac glucose uptake and suppressed expression/translocation of myocardium glucose transport-4 in dogs undergoing ischemia-reperfusion.

The following SLC2A4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the SLC2A4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCe00272	NM_001159327.1 Latest version!	Canis lupus familiaris solute carrier family 2 member 4 (SLC2A4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$342.30 $489.00
OCe287792	XM_005619478.3 Latest version!	Canis lupus familiaris solute carrier family 2 member 4 (SLC2A4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
OCe36179	XM_005619478.2 Latest version!	Canis lupus familiaris solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

SLC2A4 ( NM_001159327.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001152799.1 Canis lupus familiaris solute carrier family 2 member 4 (SLC2A4), mRNA.

Price & Availability↑

CloneID	OCe00272
Clone ID Related Accession (Same CDS sequence)	NM_001159327.1
Accession Version	NM_001159327.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1533bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-09-16
Organism	Canis lupus familiaris(dog)
Product	solute carrier family 2, facilitated glucose transporter member 4
Comment	Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from DN428922.1, DN374469.1, AAEX03003607.1, FJ797639.1, AJ388533.1, CX008986.1 and CX007098.1. On Apr 15, 2009 this sequence version replaced XM_536618.2. Sequence Note: This RefSeq record was created from transcript and genomic sequence data to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on transcript alignments. ##Evidence-Data-START## RNAseq introns :: single sample supports all introns SAMEA103936002, SAMEA2240903 [ECO:0000348] ##Evidence-Data-END## COMPLETENESS: complete on the 3' end.

ATGCCGTCGG GCTTCCAGCA GATCGGCTCG GAAGACGGGG AACCCCCTCA GCAGCGAGTC 
ACTGGGACCC TGGTCCTTGC CGTGTTCTCT GCTGTGCTCG GCTCCCTGCA GTTTGGCTAT 
AACATCGGAG TCATTAATGC GCCACAGAAG GTGATTGAAC AGAGCTACAA TGAGACATGG 
CTGGGGAGGC AGGGGCCCCA GGGGCCCAGC TCCATTCCAC CGGGCACCCT CACCACTCTC 
TGGGCTCTCT CAGTGGCCAT CTTTTCTGTG GGTGGCATGA TCTCCTCCTT CCTCATTGGC 
ATCATCTCTC AGTGGCTGGG AAGGAAGAGG GCAATGCTGG TCAACAACGT CCTGGCGGTG 
CTGGGGGGTG CCCTCATGGG CCTGGCCCAT GCTGCTGCCT CCTACGAGAT GCTCATTCTT 
GGGCGGTTCC TCATTGGCGC CTACTCAGGG CTCACATCGG GGCTGGTGCC CATGTACGTG 
GGGGAGATCG CCCCCACTCA CCTGCGGGGC GCCTTGGGGA CACTCAACCA ACTGGCCATC 
GTCATTGGCA TTCTGATCGC CCAGGTGCTG GGCTTAGAGT CCATGCTGGG CACTACCACC 
CTATGGCCAC TCCTCCTGGG CATCACAGTG CTGCCTGCCC TCCTGCAGCT GGTCCTGCTG 
CCCTTCTGCC CAGAGAGCCC TCGCTACCTC TACATAATCC GGAACCTAGA GGGGCCTGCC 
AGAAAGAGTC TGAAGCGCCT GACCGGCTGG GCTGATGTAT CTGGGGCACT GGCTGAGCTG 
AAGGAGGAGA AGCGGAAGCT GGAGCGGGAG CGGCCCCTGT CCCTGCTACA GCTCCTGGGC 
AGCCGCACCC ACCGGCAGCC TCTGGTCATC GCTGTCGTGC TGCAGCTGAG CCAGCAGCTG 
TCAGGCATCA ATGCCGTTTT CTATTATTCA ACCAGCATCT TCGAGACGGC AGGGGTCGGG 
CAGCCAGCCT ATGCGACCAT AGGAGCTGGT GTGGTCAACA CAGTCTTCAC CTTGGTCTCG 
GTGTTCCTGG TCGAGCGGGC TGGCCGTCGG ACACTCCATC TCCTGGGCCT GGCAGGAATG 
TGTGGCTGTG CCATCTTGAT GACCATAGCC CTGCTTCTGC TGGAGCGGCT TCCAGCCATG 
AGCTACGTCT CCATCGTGGC CATCTTTGGC TTTGTGGCCT TCTTTGAGAT TGGCCCAGGC 
CCCATTCCCT GGTTCATCGT GGCCGAGCTG TTCAGCCAGG GCCCCCGCCC AGCCGCCATG 
GCCGTGGCTG GCTTCTGCAA CTGGACAAGC AACTTCATCA TTGGCATGGG TTTCCAGTAT 
ATCGCGGAGG CCATGGGGCC CTATGTCTTC CTTCTGTTCG CGGTTCTCCT GCTCGCCTTC 
TTCATCTTCA CCTTCCTAAA AGTGCCTGAA ACCCGAGGCC GGACTTTTGA CCAGATCTCG 
GCTGACTTCC GCCGGACACC GTCTCTTCTA GAGCAGGAGG TGAAGCCCAG CACGGAACTC 
GATTACTTAG GACCTGACGA CGAGAATGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001152799.1
CDS	194..1726
Translation	MPSGFQQIGSEDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPQGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGALMGLAHAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESMLGTTTLWPLLLGITVLPALLQLVLLPFCPESPRYLYIIRNLEGPARKSLKRLTGWADVSGALAELKEEKRKLERERPLSLLQLLGSRTHRQPLVIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVFLVERAGRRTLHLLGLAGMCGCAILMTIALLLLERLPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFCNWTSNFIIGMGFQYIAEAMGPYVFLLFAVLLLAFFIFTFLKVPETRGRTFDQISADFRRTPSLLEQEVKPSTELDYLGPDDEND

Target ORF information:

RefSeq Version	NM_001159327.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris solute carrier family 2 member 4 (SLC2A4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001159327.1

ORF Insert Sequence:

ATGCCGTCGG GCTTCCAGCA GATCGGCTCG GAAGACGGGG AACCCCCTCA GCAGCGAGTC 
ACTGGGACCC TGGTCCTTGC CGTGTTCTCT GCTGTGCTCG GCTCCCTGCA GTTTGGCTAT 
AACATCGGAG TCATTAATGC GCCACAGAAG GTGATTGAAC AGAGCTACAA TGAGACATGG 
CTGGGGAGGC AGGGGCCCCA GGGGCCCAGC TCCATTCCAC CGGGCACCCT CACCACTCTC 
TGGGCTCTCT CAGTGGCCAT CTTTTCTGTG GGTGGCATGA TCTCCTCCTT CCTCATTGGC 
ATCATCTCTC AGTGGCTGGG AAGGAAGAGG GCAATGCTGG TCAACAACGT CCTGGCGGTG 
CTGGGGGGTG CCCTCATGGG CCTGGCCCAT GCTGCTGCCT CCTACGAGAT GCTCATTCTT 
GGGCGGTTCC TCATTGGCGC CTACTCAGGG CTCACATCGG GGCTGGTGCC CATGTACGTG 
GGGGAGATCG CCCCCACTCA CCTGCGGGGC GCCTTGGGGA CACTCAACCA ACTGGCCATC 
GTCATTGGCA TTCTGATCGC CCAGGTGCTG GGCTTAGAGT CCATGCTGGG CACTACCACC 
CTATGGCCAC TCCTCCTGGG CATCACAGTG CTGCCTGCCC TCCTGCAGCT GGTCCTGCTG 
CCCTTCTGCC CAGAGAGCCC TCGCTACCTC TACATAATCC GGAACCTAGA GGGGCCTGCC 
AGAAAGAGTC TGAAGCGCCT GACCGGCTGG GCTGATGTAT CTGGGGCACT GGCTGAGCTG 
AAGGAGGAGA AGCGGAAGCT GGAGCGGGAG CGGCCCCTGT CCCTGCTACA GCTCCTGGGC 
AGCCGCACCC ACCGGCAGCC TCTGGTCATC GCTGTCGTGC TGCAGCTGAG CCAGCAGCTG 
TCAGGCATCA ATGCCGTTTT CTATTATTCA ACCAGCATCT TCGAGACGGC AGGGGTCGGG 
CAGCCAGCCT ATGCGACCAT AGGAGCTGGT GTGGTCAACA CAGTCTTCAC CTTGGTCTCG 
GTGTTCCTGG TCGAGCGGGC TGGCCGTCGG ACACTCCATC TCCTGGGCCT GGCAGGAATG 
TGTGGCTGTG CCATCTTGAT GACCATAGCC CTGCTTCTGC TGGAGCGGCT TCCAGCCATG 
AGCTACGTCT CCATCGTGGC CATCTTTGGC TTTGTGGCCT TCTTTGAGAT TGGCCCAGGC 
CCCATTCCCT GGTTCATCGT GGCCGAGCTG TTCAGCCAGG GCCCCCGCCC AGCCGCCATG 
GCCGTGGCTG GCTTCTGCAA CTGGACAAGC AACTTCATCA TTGGCATGGG TTTCCAGTAT 
ATCGCGGAGG CCATGGGGCC CTATGTCTTC CTTCTGTTCG CGGTTCTCCT GCTCGCCTTC 
TTCATCTTCA CCTTCCTAAA AGTGCCTGAA ACCCGAGGCC GGACTTTTGA CCAGATCTCG 
GCTGACTTCC GCCGGACACC GTCTCTTCTA GAGCAGGAGG TGAAGCCCAG CACGGAACTC 
GATTACTTAG GACCTGACGA CGAGAATGAC TGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC2A4 ( XM_005619478.3 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005619535.3 Canis lupus familiaris solute carrier family 2 member 4 (SLC2A4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe287792
Clone ID Related Accession (Same CDS sequence)	XM_005619478.3
Accession Version	XM_005619478.3 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1608bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2017-09-04
Organism	Canis lupus familiaris(dog)
Product	solute carrier family 2, facilitated glucose transporter member 4 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_006587.3) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 5, 2017 this sequence version replaced XM_005619478.2. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 7.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGACCGAGA TGTCCTTTTC GGAAGTACCT CTCTTGAGTC TGTTGGGGGC CTCCCGTGGC 
GCGCTGAGTG AAGCCCTGAG GGGAGGAAAG AGGACCGAAG CCCCCACAGA CGGGGAACCC 
CCTCAGCAGC GAGTCACTGG GACCCTGGTC CTTGCCGTGT TCTCTGCTGT GCTCGGCTCC 
CTGCAGTTTG GCTATAACAT CGGAGTCATT AATGCGCCAC AGAAGGTGAT TGAACAGAGC 
TACAATGAGA CATGGCTGGG GAGGCAGGGG CCCCAGGGGC CCAGCTCCAT TCCACCGGGC 
ACCCTCACCA CTCTCTGGGC TCTCTCAGTG GCCATCTTTT CTGTGGGTGG CATGATCTCC 
TCCTTCCTCA TTGGCATCAT CTCTCAGTGG CTGGGAAGGA AGAGGGCAAT GCTGGTCAAC 
AACGTCCTGG CGGTGCTGGG GGGTGCCCTC ATGGGCCTGG CCCATGCTGC TGCCTCCTAC 
GAGATGCTCA TTCTTGGGCG GTTCCTCATT GGCGCCTACT CAGGGCTCAC ATCGGGGCTG 
GTGCCCATGT ACGTGGGGGA GATCGCCCCC ACTCACCTGC GGGGCGCCTT GGGGACACTC 
AACCAACTGG CCATCGTCAT TGGCATTCTG ATCGCCCAGG TGCTGGGCTT AGAGTCCATG 
CTGGGCACTA CCACCCTATG GCCACTCCTC CTGGGCATCA CAGTGCTGCC TGCCCTCCTG 
CAGCTGGTCC TGCTGCCCTT CTGCCCAGAG AGCCCTCGCT ACCTCTACAT AATCCGGAAC 
CTAGAGGGGC CTGCCAGAAA GAGTCTGAAG CGCCTGACCG GCTGGGCTGA TGTATCTGGG 
GCACTGGCTG AGCTGAAGGA GGAGAAGCGG AAGCTGGAGC GGGAGCGGCC CCTGTCCCTG 
CTACAGCTCC TGGGCAGCCG CACCCACCGG CAGCCTCTGG TCATCGCTGT CGTGCTGCAG 
CTGAGCCAGC AGCTGTCAGG CATCAATGCC GTTTTCTATT ATTCAACCAG CATCTTCGAG 
ACGGCAGGGG TCGGGCAGCC AGCCTATGCG ACCATAGGAG CTGGTGTGGT CAACACAGTC 
TTCACCTTGG TCTCGGTGTT CCTGGTCGAG CGGGCTGGCC GTCGGACACT CCATCTCCTG 
GGCCTGGCAG GAATGTGTGG CTGTGCCATC TTGATGACCA TAGCCCTGCT TCTGCTGGAG 
CGGCTTCCAG CCATGAGCTA CGTCTCCATC GTGGCCATCT TTGGCTTTGT GGCCTTCTTT 
GAGATTGGCC CAGGCCCCAT TCCCTGGTTC ATCGTGGCCG AGCTGTTCAG CCAGGGCCCC 
CGCCCAGCCG CCATGGCCGT GGCTGGCTTC TGCAACTGGA CAAGCAACTT CATCATTGGC 
ATGGGTTTCC AGTATATCGC GGAGGCCATG GGGCCCTATG TCTTCCTTCT GTTCGCGGTT 
CTCCTGCTCG CCTTCTTCAT CTTCACCTTC CTAAAAGTGC CTGAAACCCG AGGCCGGACT 
TTTGACCAGA TCTCGGCTGA CTTCCGCCGG ACACCGTCTC TTCTAGAGCA GGAGGTGAAG 
CCCAGCACGG AACTCGATTA CTTAGGACCT GACGACGAGA ATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005619535.3
CDS	7..1614
Translation	MTEMSFSEVPLLSLLGASRGALSEALRGGKRTEAPTDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPQGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGALMGLAHAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESMLGTTTLWPLLLGITVLPALLQLVLLPFCPESPRYLYIIRNLEGPARKSLKRLTGWADVSGALAELKEEKRKLERERPLSLLQLLGSRTHRQPLVIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVFLVERAGRRTLHLLGLAGMCGCAILMTIALLLLERLPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFCNWTSNFIIGMGFQYIAEAMGPYVFLLFAVLLLAFFIFTFLKVPETRGRTFDQISADFRRTPSLLEQEVKPSTELDYLGPDDEND

Target ORF information:

RefSeq Version	XM_005619478.3
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris solute carrier family 2 member 4 (SLC2A4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005619478.3

ORF Insert Sequence:

ATGACCGAGA TGTCCTTTTC GGAAGTACCT CTCTTGAGTC TGTTGGGGGC CTCCCGTGGC 
GCGCTGAGTG AAGCCCTGAG GGGAGGAAAG AGGACCGAAG CCCCCACAGA CGGGGAACCC 
CCTCAGCAGC GAGTCACTGG GACCCTGGTC CTTGCCGTGT TCTCTGCTGT GCTCGGCTCC 
CTGCAGTTTG GCTATAACAT CGGAGTCATT AATGCGCCAC AGAAGGTGAT TGAACAGAGC 
TACAATGAGA CATGGCTGGG GAGGCAGGGG CCCCAGGGGC CCAGCTCCAT TCCACCGGGC 
ACCCTCACCA CTCTCTGGGC TCTCTCAGTG GCCATCTTTT CTGTGGGTGG CATGATCTCC 
TCCTTCCTCA TTGGCATCAT CTCTCAGTGG CTGGGAAGGA AGAGGGCAAT GCTGGTCAAC 
AACGTCCTGG CGGTGCTGGG GGGTGCCCTC ATGGGCCTGG CCCATGCTGC TGCCTCCTAC 
GAGATGCTCA TTCTTGGGCG GTTCCTCATT GGCGCCTACT CAGGGCTCAC ATCGGGGCTG 
GTGCCCATGT ACGTGGGGGA GATCGCCCCC ACTCACCTGC GGGGCGCCTT GGGGACACTC 
AACCAACTGG CCATCGTCAT TGGCATTCTG ATCGCCCAGG TGCTGGGCTT AGAGTCCATG 
CTGGGCACTA CCACCCTATG GCCACTCCTC CTGGGCATCA CAGTGCTGCC TGCCCTCCTG 
CAGCTGGTCC TGCTGCCCTT CTGCCCAGAG AGCCCTCGCT ACCTCTACAT AATCCGGAAC 
CTAGAGGGGC CTGCCAGAAA GAGTCTGAAG CGCCTGACCG GCTGGGCTGA TGTATCTGGG 
GCACTGGCTG AGCTGAAGGA GGAGAAGCGG AAGCTGGAGC GGGAGCGGCC CCTGTCCCTG 
CTACAGCTCC TGGGCAGCCG CACCCACCGG CAGCCTCTGG TCATCGCTGT CGTGCTGCAG 
CTGAGCCAGC AGCTGTCAGG CATCAATGCC GTTTTCTATT ATTCAACCAG CATCTTCGAG 
ACGGCAGGGG TCGGGCAGCC AGCCTATGCG ACCATAGGAG CTGGTGTGGT CAACACAGTC 
TTCACCTTGG TCTCGGTGTT CCTGGTCGAG CGGGCTGGCC GTCGGACACT CCATCTCCTG 
GGCCTGGCAG GAATGTGTGG CTGTGCCATC TTGATGACCA TAGCCCTGCT TCTGCTGGAG 
CGGCTTCCAG CCATGAGCTA CGTCTCCATC GTGGCCATCT TTGGCTTTGT GGCCTTCTTT 
GAGATTGGCC CAGGCCCCAT TCCCTGGTTC ATCGTGGCCG AGCTGTTCAG CCAGGGCCCC 
CGCCCAGCCG CCATGGCCGT GGCTGGCTTC TGCAACTGGA CAAGCAACTT CATCATTGGC 
ATGGGTTTCC AGTATATCGC GGAGGCCATG GGGCCCTATG TCTTCCTTCT GTTCGCGGTT 
CTCCTGCTCG CCTTCTTCAT CTTCACCTTC CTAAAAGTGC CTGAAACCCG AGGCCGGACT 
TTTGACCAGA TCTCGGCTGA CTTCCGCCGG ACACCGTCTC TTCTAGAGCA GGAGGTGAAG 
CCCAGCACGG AACTCGATTA CTTAGGACCT GACGACGAGA ATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

SLC2A4 ( XM_005619478.2 ) cDNA ORF clone, Canis lupus familiaris(dog) -> XP_005619535.2 Canis lupus familiaris solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OCe36179
Clone ID Related Accession (Same CDS sequence)	XM_005619478.2
Accession Version	XM_005619478.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1620bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2015-09-16
Organism	Canis lupus familiaris(Dog)
Product	solute carrier family 2, facilitated glucose transporter member 4 isoform X1
Comment	MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003726057.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Sep 17, 2015 this sequence version replaced XM_005619478.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Canis lupus familiaris Annotation Release 104 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.4 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCGGGGAG GAATGACCGA GATGTCCTTT TCGGAAGTAC CTCTCTTGAG TCTGTTGGGG 
GCCTCCCGTG GCGCGCTGAG TGAAGCCCTG AGGGGAGGAA AGAGGACCGA AGCCCCCACA 
GACGGGGAAC CCCCTCAGCA GCGAGTCACT GGGACCCTGG TCCTTGCCGT GTTCTCTGCT 
GTGCTCGGCT CCCTGCAGTT TGGCTATAAC ATCGGAGTCA TTAATGCGCC ACAGAAGGTG 
ATTGAACAGA GCTACAATGA GACATGGCTG GGGAGGCAGG GGCCCCAGGG GCCCAGCTCC 
ATTCCACCGG GCACCCTCAC CACTCTCTGG GCTCTCTCAG TGGCCATCTT TTCTGTGGGT 
GGCATGATCT CCTCCTTCCT CATTGGCATC ATCTCTCAGT GGCTGGGAAG GAAGAGGGCA 
ATGCTGGTCA ACAACGTCCT GGCGGTGCTG GGGGGTGCCC TCATGGGCCT GGCCCATGCT 
GCTGCCTCCT ACGAGATGCT CATTCTTGGG CGGTTCCTCA TTGGCGCCTA CTCAGGGCTC 
ACATCGGGGC TGGTGCCCAT GTACGTGGGG GAGATCGCCC CCACTCACCT GCGGGGCGCC 
TTGGGGACAC TCAACCAACT GGCCATCGTC ATTGGCATTC TGATCGCCCA GGTGCTGGGC 
TTAGAGTCCA TGCTGGGCAC TACCACCCTA TGGCCACTCC TCCTGGGCAT CACAGTGCTG 
CCTGCCCTCC TGCAGCTGGT CCTGCTGCCC TTCTGCCCAG AGAGCCCTCG CTACCTCTAC 
ATAATCCGGA ACCTAGAGGG GCCTGCCAGA AAGAGTCTGA AGCGCCTGAC CGGCTGGGCT 
GATGTATCTG GGGCACTGGC TGAGCTGAAG GAGGAGAAGC GGAAGCTGGA GCGGGAGCGG 
CCCCTGTCCC TGCTACAGCT CCTGGGCAGC CGCACCCACC GGCAGCCTCT GGTCATCGCT 
GTCGTGCTGC AGCTGAGCCA GCAGCTGTCA GGCATCAATG CCGTTTTCTA TTATTCAACC 
AGCATCTTCG AGACGGCAGG GGTCGGGCAG CCAGCCTATG CGACCATAGG AGCTGGTGTG 
GTCAACACAG TCTTCACCTT GGTCTCGGTG TTCCTGGTCG AGCGGGCTGG CCGTCGGACA 
CTCCATCTCC TGGGCCTGGC AGGAATGTGT GGCTGTGCCA TCTTGATGAC CATAGCCCTG 
CTTCTGCTGG AGCGGCTTCC AGCCATGAGC TACGTCTCCA TCGTGGCCAT CTTTGGCTTT 
GTGGCCTTCT TTGAGATTGG CCCAGGCCCC ATTCCCTGGT TCATCGTGGC CGAGCTGTTC 
AGCCAGGGCC CCCGCCCAGC CGCCATGGCC GTGGCTGGCT TCTGCAACTG GACAAGCAAC 
TTCATCATTG GCATGGGTTT CCAGTATATC GCGGAGGCCA TGGGGCCCTA TGTCTTCCTT 
CTGTTCGCGG TTCTCCTGCT CGCCTTCTTC ATCTTCACCT TCCTAAAAGT GCCTGAAACC 
CGAGGCCGGA CTTTTGACCA GATCTCGGCT GACTTCCGCC GGACACCGTC TCTTCTAGAG 
CAGGAGGTGA AGCCCAGCAC GGAACTCGAT TACTTAGGAC CTGACGACGA GAATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_005619535.2
CDS	18..1637
Translation	MRGGMTEMSFSEVPLLSLLGASRGALSEALRGGKRTEAPTDGEPPQQRVTGTLVLAVFSAVLGSLQFGYNIGVINAPQKVIEQSYNETWLGRQGPQGPSSIPPGTLTTLWALSVAIFSVGGMISSFLIGIISQWLGRKRAMLVNNVLAVLGGALMGLAHAAASYEMLILGRFLIGAYSGLTSGLVPMYVGEIAPTHLRGALGTLNQLAIVIGILIAQVLGLESMLGTTTLWPLLLGITVLPALLQLVLLPFCPESPRYLYIIRNLEGPARKSLKRLTGWADVSGALAELKEEKRKLERERPLSLLQLLGSRTHRQPLVIAVVLQLSQQLSGINAVFYYSTSIFETAGVGQPAYATIGAGVVNTVFTLVSVFLVERAGRRTLHLLGLAGMCGCAILMTIALLLLERLPAMSYVSIVAIFGFVAFFEIGPGPIPWFIVAELFSQGPRPAAMAVAGFCNWTSNFIIGMGFQYIAEAMGPYVFLLFAVLLLAFFIFTFLKVPETRGRTFDQISADFRRTPSLLEQEVKPSTELDYLGPDDEND

Target ORF information:

RefSeq Version	XM_005619478.2
Organism	Canis lupus familiaris(Dog)
Definition	Canis lupus familiaris solute carrier family 2 (facilitated glucose transporter), member 4 (SLC2A4), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_005619478.2

ORF Insert Sequence:

ATGCGGGGAG GAATGACCGA GATGTCCTTT TCGGAAGTAC CTCTCTTGAG TCTGTTGGGG 
GCCTCCCGTG GCGCGCTGAG TGAAGCCCTG AGGGGAGGAA AGAGGACCGA AGCCCCCACA 
GACGGGGAAC CCCCTCAGCA GCGAGTCACT GGGACCCTGG TCCTTGCCGT GTTCTCTGCT 
GTGCTCGGCT CCCTGCAGTT TGGCTATAAC ATCGGAGTCA TTAATGCGCC ACAGAAGGTG 
ATTGAACAGA GCTACAATGA GACATGGCTG GGGAGGCAGG GGCCCCAGGG GCCCAGCTCC 
ATTCCACCGG GCACCCTCAC CACTCTCTGG GCTCTCTCAG TGGCCATCTT TTCTGTGGGT 
GGCATGATCT CCTCCTTCCT CATTGGCATC ATCTCTCAGT GGCTGGGAAG GAAGAGGGCA 
ATGCTGGTCA ACAACGTCCT GGCGGTGCTG GGGGGTGCCC TCATGGGCCT GGCCCATGCT 
GCTGCCTCCT ACGAGATGCT CATTCTTGGG CGGTTCCTCA TTGGCGCCTA CTCAGGGCTC 
ACATCGGGGC TGGTGCCCAT GTACGTGGGG GAGATCGCCC CCACTCACCT GCGGGGCGCC 
TTGGGGACAC TCAACCAACT GGCCATCGTC ATTGGCATTC TGATCGCCCA GGTGCTGGGC 
TTAGAGTCCA TGCTGGGCAC TACCACCCTA TGGCCACTCC TCCTGGGCAT CACAGTGCTG 
CCTGCCCTCC TGCAGCTGGT CCTGCTGCCC TTCTGCCCAG AGAGCCCTCG CTACCTCTAC 
ATAATCCGGA ACCTAGAGGG GCCTGCCAGA AAGAGTCTGA AGCGCCTGAC CGGCTGGGCT 
GATGTATCTG GGGCACTGGC TGAGCTGAAG GAGGAGAAGC GGAAGCTGGA GCGGGAGCGG 
CCCCTGTCCC TGCTACAGCT CCTGGGCAGC CGCACCCACC GGCAGCCTCT GGTCATCGCT 
GTCGTGCTGC AGCTGAGCCA GCAGCTGTCA GGCATCAATG CCGTTTTCTA TTATTCAACC 
AGCATCTTCG AGACGGCAGG GGTCGGGCAG CCAGCCTATG CGACCATAGG AGCTGGTGTG 
GTCAACACAG TCTTCACCTT GGTCTCGGTG TTCCTGGTCG AGCGGGCTGG CCGTCGGACA 
CTCCATCTCC TGGGCCTGGC AGGAATGTGT GGCTGTGCCA TCTTGATGAC CATAGCCCTG 
CTTCTGCTGG AGCGGCTTCC AGCCATGAGC TACGTCTCCA TCGTGGCCAT CTTTGGCTTT 
GTGGCCTTCT TTGAGATTGG CCCAGGCCCC ATTCCCTGGT TCATCGTGGC CGAGCTGTTC 
AGCCAGGGCC CCCGCCCAGC CGCCATGGCC GTGGCTGGCT TCTGCAACTG GACAAGCAAC 
TTCATCATTG GCATGGGTTT CCAGTATATC GCGGAGGCCA TGGGGCCCTA TGTCTTCCTT 
CTGTTCGCGG TTCTCCTGCT CGCCTTCTTC ATCTTCACCT TCCTAAAAGT GCCTGAAACC 
CGAGGCCGGA CTTTTGACCA GATCTCGGCT GACTTCCGCC GGACACCGTC TCTTCTAGAG 
CAGGAGGTGA AGCCCAGCAC GGAACTCGAT TACTTAGGAC CTGACGACGA GAATGACTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Conditioning causes an increase in glucose transporter-4 levels in mononuclear cells in sled dogs.
The international journal of biochemistry & cell biology55227-31(2014 Oct)
Schnurr TM,Reynolds AJ,Gustafson SJ,Duffy LK,Dunlap KL

Intervention of rosiglitazone on myocardium Glut-4 mRNA expression during ischemia-reperfusion injury in cardio-pulmonary bypass in dogs.
Molecular and cellular biochemistry373(1-2)279-84(2013 Jan)
Liu B,Liang G,Xu G,Liu D,Cai Q,Gao Z

Chronic heart failure selectively induces regional heterogeneity of insulin-responsive glucose transporters.
American journal of physiology. Regulatory, integrative and comparative physiology301(5)R1300-6(2011 Nov)
Ware B,Bevier M,Nishijima Y,Rogers S,Carnes CA,Lacombe VA

Cardiac glucose uptake and suppressed expression/translocation of myocardium glucose transport-4 in dogs undergoing ischemia-reperfusion.
Experimental biology and medicine (Maywood, N.J.)233(9)1142-8(2008 Sep)
Liang GY,Cai QY,Niu YM,Zheng H,Gao ZY,Liu DX,Xu G

A method for the large-scale cloning of nuclear proteins and nuclear targeting sequences on a functional basis.
Analytical biochemistry284(2)231-9(2000 Sep)
Pichon B,Mercan D,Pouillon V,Christophe-Hobertus C,Christophe D

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SLC2A4 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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