COL1A1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	COL1A1
Entrez Gene ID	403651
Full Name	collagen type I alpha 1 chain
General protein information	Preferred Names collagen type I alpha 1 chain Names collagen alpha-1(I) chain alpha-1 type I collagen type I collagen pre-pro-alpha1(I) chain
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003090.1	NP_001003090.1	collagen alpha-1(I) chain precursor

Pathways from BioSystems

Homologies

Bos taurus (cattle)	COL1A1	NP_001029211.1
Mus musculus (house mouse)	Col1a1	NP_031768.2
Danio rerio (zebrafish)	col1a1a	NP_954684.1
Pan troglodytes (chimpanzee)	COL1A1	XP_001169409.1
	COL1A1	XP_001096194.2
Canis lupus familiaris (dog)	COL1A1	NP_001003090.1
Rattus norvegicus (Norway rat)	Col1a1	NP_445756.1
Homo sapiens (human)	COL1A1	NP_000079.2
Xenopus tropicalis (tropical clawed frog)	LOC496414	NP_001011005.1

Gene Ontology
Bibliography

Related articles in PubMed

Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-?/miR-185/CoLA1 signaling in a canine model.
Ding X, Yu C, Liu Y, Yan S, Li W, Wang D, Sun L, Han Y, Li M, Zhang S, Yun F, Zhao H, Li Y
Oncotarget7(36)57545-57555(2016 Sep)

The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair.
Oecal S, Socher E, Uthoff M, Ernst C, Zaucke F, Sticht H, Baumann U, Gebauer JM
The Journal of biological chemistry291(24)12612-26(2016 Jun)

Genetic basis of cranial cruciate ligament rupture (CCLR) in dogs.
Baird AE, Carter SD, Innes JF, Ollier WE, Short AD
Connective tissue research55(4)275-81(2014 Aug)

Synoviocyte neotissues towards in vitro meniscal tissue engineering.
Warnock JJ, Duesterdieck-Zellmer KF, Bobe G, Baltzer WI, Ott J
Research in veterinary science95(3)1201-9(2013 Dec)

Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy.
Friedrichs J, Torkko JM, Helenius J, Ter?v?inen TP, F?llekrug J, Muller DJ, Simons K, Manninen A
The Journal of biological chemistry282(40)29375-83(2007 Oct)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Data show that heat shock protein 47 (HSP47/SERPINH1) double mutant with histidine His(273) and His(274) exchanged for asparagines exhibits a much less pronounced pH dependence of collagen binding.
Title: The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair.

identified SNPs in key genes involved in ligament strength, stability and extracellular matrix formation (COL5A1, COL5A2, COL1A1, COL3A1, COL11A1, COL24A1, FBN1, LOX, LTBP2) which were significantly associated with CCLR susceptibility
Title: Genetic basis of cranial cruciate ligament rupture (CCLR) in dogs.

both galectin-3 and -9 are required for optimal long term cell adhesion to both collagen I and laminin-111
Title: Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy.

The following COL1A1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the COL1A1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe34240	NM_001003090.1 Latest version!	Canis lupus familiaris collagen type I alpha 1 chain (COL1A1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$797.30 $1139.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

COL1A1 ( NM_001003090.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003090.1 Canis lupus familiaris collagen type I alpha 1 chain (COL1A1), mRNA.

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CloneID	OCe34240
Clone ID Related Accession (Same CDS sequence)	NM_001003090.1
Accession Version	NM_001003090.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4383bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Canis lupus familiaris(dog)
Product	collagen alpha-1(I) chain precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF153062.1. ##Evidence-Data-START## Transcript exon combination :: AF153062.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547744, SAMEA4547746 [ECO:0000348] ##Evidence-Data-END##

ATGTTCAGCT TTGTGGACCT CCGGCTCCTG CTCCTCTTAG CGGCCACCGC CCTCCTGACG 
CACGGCCAAG AGGAGGGCCA AGAAGAAGAC ATCCCACCAG TCACCTGCGT ACAGAACGGC 
CTCAGGTACT ATGACCGAGA CGTATGGAAA CCCGAGGCCT GCCGGATCTG TGTCTGCGAC 
AACGGCAACG TGTTGTGCGA TGACGTGATC TGCGACGAAA CCAAGAACTG CCCCGGCGCC 
CAAGTCCCCC CGGGCGAGTG CTGCCCCGTC TGCCCCGACG GCGAGGCGTC ACCTACCGAC 
CAAGAAACCA CAGGAGTCGA GGGACCCAAA GGAGACACCG GCCCCCGAGG TCCAAGGGGA 
CCTGCCGGGC CCCCTGGCCG AGATGGCATC CCCGGACAGC CTGGACTTCC CGGACCCCCT 
GGACCTCCCG GACCCCCTGG ACCCCCTGGC CTCGGAGGAA ACTTTGCTCC CCAAATGTCT 
TATGGCTATG ATGAGAAATC AACTGGAGGA ATCTCCGTGC CTGGCCCCAT GGGTCCTTCT 
GGTCCTCGTG GTCTCCCTGG CCCCCCTGGC GCACCTGGTC CTCAAGGTTT CCAAGGCCCC 
CCTGGTGAAC CTGGCGAGCC TGGAGCCTCA GGTCCCATGG GTCCCCGTGG TCCCCCTGGC 
CCCCCTGGCA AGAACGGAGA TGACGGTGAA GCTGGAAAGC CTGGTCGTCC TGGTGAGCGT 
GGGCCTCCTG GGCCTCAGGG TGCTCGGGGA TTGCCTGGAA CAGCTGGCCT TCCTGGAATG 
AAGGGACACA GAGGTTTCAG TGGTTTGGAT GGTGCCAAGG GAGATGCTGG TCCTGCTGGT 
CCCAAGGGTG AGCCTGGTAG CCCCGGTGAA AATGGAGCTC CTGGCCAGAT GGGCCCCCGT 
GGTCTGCCCG GTGAAAGAGG TCGCCCTGGA GCCCCTGGCC CTGCCGGTGC TCGTGGAAAC 
GATGGTGCTA CTGGTGCTGC TGGGCCCCCT GGTCCCACTG GCCCCGCTGG TCCTCCTGGC 
TTCCCCGGTG CTGTTGGTGC TAAGGGTGAA GCTGGTCCCC AAGGAGCCCG TGGCTCTGAA 
GGTCCCCAGG GCGTGCGTGG TGAGCCCGGC CCCCCTGGCC CTGCTGGTGC TGCCGGCCCT 
GCCGGAAACC CCGGTGCTGA TGGACAGCCT GGTGCTAAAG GTGCTAACGG CGCTCCTGGC 
ATTGCTGGTG CTCCCGGCTT CCCCGGTGCC CGAGGCCCCT CTGGACCCCA GGGCCCCAGC 
GGTCCTCCTG GTCCCAAGGG TAACAGCGGT GAACCTGGTG CTCCCGGAAA CAAAGGAGAC 
ACTGGTGCCA AGGGAGAGCC CGGCCCCACT GGTATTCAAG GTCCCCCTGG CCCTGCTGGG 
GAAGAAGGAA AGCGAGGAGC CCGAGGTGAA CCTGGACCCA CTGGCCTGCC CGGACCCCCT 
GGCGAGCGTG GTGGACCTGG TAGCCGTGGT TTCCCTGGTG CAGATGGTGT CGCTGGTCCC 
AAGGGTCCCG CTGGTGAACG TGGTTCTCCT GGTCCCGCTG GGCCCAAAGG TTCTCCTGGT 
GAAGCTGGTC GCCCTGGTGA AGCTGGTCTG CCTGGTGCCA AGGGTCTGAC TGGAAGTCCT 
GGCAGCCCCG GTCCAGATGG CAAAACTGGC CCCCCTGGTC CCGCTGGTCA GGATGGTCGT 
CCCGGACCCC CAGGCCCCCC TGGTGCCCGT GGTCAAGCTG GTGTGATGGG ATTCCCTGGG 
CCTAAAGGTG CCGCTGGAGA GCCTGGCAAG GCTGGAGAGC GTGGTGTCCC TGGCCCCCCT 
GGTGCTGTTG GTCCTGCTGG CAAAGATGGA GAAGCAGGAG CTCAGGGGCC CCCTGGCCCT 
GCTGGCCCCG CTGGCGAGAG AGGTGAACAA GGTCCTGCTG GCTCCCCCGG ATTCCAGGGT 
CTCCCTGGCC CTGCTGGTCC TCCCGGCGAA GCAGGCAAAC CTGGTGAACA GGGTGTTCCT 
GGCGACCTTG GTGCCCCCGG CCCCTCTGGA GCAAGAGGCG AGAGAGGCTT TCCTGGTGAA 
CGTGGTGTGC AAGGTCCCCC CGGTCCTGCA GGTCCCCGAG GAGCCAACGG TGCCCCTGGC 
AATGATGGTG CTAAGGGTGA TGCTGGTGCC CCTGGAGCCC CAGGTAGCCA GGGCGCTCCT 
GGCCTTCAGG GAATGCCTGG TGAACGAGGT GCAGCTGGTC TTCCTGGCCC TAAGGGTGAC 
AGAGGTGATG CCGGTCCCAA AGGTGCTGAT GGTTCTCCTG GCAAAGATGG TGTCCGTGGT 
CTGACTGGCC CCATTGGTCC TCCTGGCCCT GCTGGTGCCC CTGGTGACAA GGGTGAAGCT 
GGTCCTAGCG GCCCTGCTGG TCCCACTGGA GCTCGTGGTG CCCCCGGAGA CCGTGGTGAG 
CCTGGTCCCC CTGGTCCTGC TGGCTTCGCT GGGCCCCCCG GTGCTGACGG CCAACCTGGT 
GCTAAAGGTG AACCCGGTGA TGCTGGTGCT AAAGGCGACG CTGGTCCCCC TGGCCCTGCT 
GGACCCACTG GACCTCCCGG CCCCATTGGT AACGTTGGTG CTCCTGGACC CAAAGGTGCT 
CGTGGCAGCG CCGGTCCCCC TGGTGCTACT GGTTTCCCTG GTGCTGCTGG CCGCGTCGGT 
CCCCCCGGCC CCTCTGGAAA TGCTGGACCC CCTGGCCCTC CTGGCCCTGC TGGCAAAGAA 
GGCGGCAAAG GCGCCCGTGG TGAGACTGGC CCTGCTGGAC GTCCCGGTGA AGTCGGTCCC 
CCTGGTCCCC CTGGCCCTGC TGGCGAGAAA GGATCCCCTG GTGCTGATGG ACCCGCTGGT 
GCTCCCGGCA CTCCCGGACC TCAAGGCATT GCTGGACAGC GTGGTGTGGT CGGTCTGCCC 
GGTCAACGAG GAGAAAGAGG CTTCCCTGGT CTTCCCGGCC CCTCTGGCGA ACCTGGCAAA 
CAAGGTCCTT CTGGAACAAG TGGTGAACGT GGTCCCCCTG GTCCCATGGG CCCCCCTGGA 
TTAGCTGGAC CCCCTGGCGA GTCTGGACGG GAGGGATCTC CTGGTGCTGA AGGCTCCCCT 
GGACGAGATG GTTCTCCTGG CCCCAAGGGT GACCGTGGTG AGACCGGCCC TGCTGGACCC 
CCTGGTGCCC CCGGTGCCCC TGGTGCTCCT GGCCCTGTCG GCCCTGCTGG CAAGAACGGT 
GACCGCGGTG AGACTGGTCC TGCTGGTCCT GCTGGCCCAA TCGGCCCTGT TGGTGCTCGT 
GGTCCTGCTG GACCCCAAGG CCCCCGTGGT GACAAGGGTG AGACAGGCGA ACAGGGTGAC 
AGAGGCATAA AGGGTCACCG TGGCTTCTCT GGTCTTCAGG GTCCTCCTGG CCCTCCCGGC 
TCTCCTGGTG AACAAGGTCC TTCTGGAGCT TCTGGTCCTG CTGGTCCCCG AGGTCCCCCT 
GGCTCTGCTG GTTCTCCTGG CAAAGACGGA CTCAACGGTC TCCCAGGCCC CATTGGCCCC 
CCCGGTCCTC GTGGTCGCAC TGGTGATGCC GGTCCTGTTG GTCCCCCTGG CCCTCCTGGA 
CCCCCTGGTC CCCCCGGTCC TCCCAGCGGC GGTTTCGACT TCAGCTTCCT GCCCCAGCCA 
CCTCAGGAGA AGGCTCACGA TGGCGGCCGC TACTACCGGG CCGATGATGC CAACGTGGTC 
CGTGACCGTG ACCTCGAGGT AGACACCACC CTCAAGAGCC TGAGCCAGCA GATCGAGAAC 
ATCCGGAGCC CTGAAGGAAG CCGCAAGAAC CCTGCCCGCA CCTGCCGCGA CCTCAAGATG 
TGCCACTCCG ACTGGAAGAG CGGAGAATAC TGGATTGACC CCAACCAAGG ATGCAACCTC 
GATGCCATCA AGGTTTTCTG CAACATGGAG ACAGGTGAGA CCTGCGTATA CCCCACTCAG 
CCCCAGGTGG CCCAGAAGAA CTGGTACATC AGCAAGAACC CCAAGGAGAA GAGACACGTC 
TGGTACGGCG AGAGCATGAC CGACGGATTC CAGTTCGAGT ATGGTGGCCA GGGCTCCGAT 
CCTGCCGATG TGGCCATCCA GCTGACCTTC CTGCGCCTGA TGTCCACCGA GGCCTCCCAG 
AACATCACCT ACCACTGCAA GAACAGCGTG GCCTACATGG ACCAGCAGAC CGGCAACCTC 
AAGAAGGCCC TGCTCCTCCA GGGTTCCAAC GAGATCGAGA TCCGGGCCGA GGGCAACAGC 
CGCTTCACCT ACAGTGTCAC CTACGACGGC TGCACGAGTC ACACTGGAGC CTGGGGCAAG 
ACAGTGATCG AATACAAAAC CACCAAGACC TCCCGTTTGC CCATCATCGA TGTGGCACCA 
TTGGACGTTG GCGCCCCAGA CCAGGAATTC GGCATGGATA TTGGCCCTGT CTGCTTCCTG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003090.1
CDS	89..4471
Translation	MFSFVDLRLLLLLAATALLTHGQEEGQEEDIPPVTCVQNGLRYYDRDVWKPEACRICVCDNGNVLCDDVICDETKNCPGAQVPPGECCPVCPDGEASPTDQETTGVEGPKGDTGPRGPRGPAGPPGRDGIPGQPGLPGPPGPPGPPGPPGLGGNFAPQMSYGYDEKSTGGISVPGPMGPSGPRGLPGPPGAPGPQGFQGPPGEPGEPGASGPMGPRGPPGPPGKNGDDGEAGKPGRPGERGPPGPQGARGLPGTAGLPGMKGHRGFSGLDGAKGDAGPAGPKGEPGSPGENGAPGQMGPRGLPGERGRPGAPGPAGARGNDGATGAAGPPGPTGPAGPPGFPGAVGAKGEAGPQGARGSEGPQGVRGEPGPPGPAGAAGPAGNPGADGQPGAKGANGAPGIAGAPGFPGARGPSGPQGPSGPPGPKGNSGEPGAPGNKGDTGAKGEPGPTGIQGPPGPAGEEGKRGARGEPGPTGLPGPPGERGGPGSRGFPGADGVAGPKGPAGERGSPGPAGPKGSPGEAGRPGEAGLPGAKGLTGSPGSPGPDGKTGPPGPAGQDGRPGPPGPPGARGQAGVMGFPGPKGAAGEPGKAGERGVPGPPGAVGPAGKDGEAGAQGPPGPAGPAGERGEQGPAGSPGFQGLPGPAGPPGEAGKPGEQGVPGDLGAPGPSGARGERGFPGERGVQGPPGPAGPRGANGAPGNDGAKGDAGAPGAPGSQGAPGLQGMPGERGAAGLPGPKGDRGDAGPKGADGSPGKDGVRGLTGPIGPPGPAGAPGDKGEAGPSGPAGPTGARGAPGDRGEPGPPGPAGFAGPPGADGQPGAKGEPGDAGAKGDAGPPGPAGPTGPPGPIGNVGAPGPKGARGSAGPPGATGFPGAAGRVGPPGPSGNAGPPGPPGPAGKEGGKGARGETGPAGRPGEVGPPGPPGPAGEKGSPGADGPAGAPGTPGPQGIAGQRGVVGLPGQRGERGFPGLPGPSGEPGKQGPSGTSGERGPPGPMGPPGLAGPPGESGREGSPGAEGSPGRDGSPGPKGDRGETGPAGPPGAPGAPGAPGPVGPAGKNGDRGETGPAGPAGPIGPVGARGPAGPQGPRGDKGETGEQGDRGIKGHRGFSGLQGPPGPPGSPGEQGPSGASGPAGPRGPPGSAGSPGKDGLNGLPGPIGPPGPRGRTGDAGPVGPPGPPGPPGPPGPPSGGFDFSFLPQPPQEKAHDGGRYYRADDANVVRDRDLEVDTTLKSLSQQIENIRSPEGSRKNPARTCRDLKMCHSDWKSGEYWIDPNQGCNLDAIKVFCNMETGETCVYPTQPQVAQKNWYISKNPKEKRHVWYGESMTDGFQFEYGGQGSDPADVAIQLTFLRLMSTEASQNITYHCKNSVAYMDQQTGNLKKALLLQGSNEIEIRAEGNSRFTYSVTYDGCTSHTGAWGKTVIEYKTTKTSRLPIIDVAPLDVGAPDQEFGMDIGPVCFL

Target ORF information:

RefSeq Version	NM_001003090.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris collagen type I alpha 1 chain (COL1A1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003090.1

ORF Insert Sequence:

ATGTTCAGCT TTGTGGACCT CCGGCTCCTG CTCCTCTTAG CGGCCACCGC CCTCCTGACG 
CACGGCCAAG AGGAGGGCCA AGAAGAAGAC ATCCCACCAG TCACCTGCGT ACAGAACGGC 
CTCAGGTACT ATGACCGAGA CGTATGGAAA CCCGAGGCCT GCCGGATCTG TGTCTGCGAC 
AACGGCAACG TGTTGTGCGA TGACGTGATC TGCGACGAAA CCAAGAACTG CCCCGGCGCC 
CAAGTCCCCC CGGGCGAGTG CTGCCCCGTC TGCCCCGACG GCGAGGCGTC ACCTACCGAC 
CAAGAAACCA CAGGAGTCGA GGGACCCAAA GGAGACACCG GCCCCCGAGG TCCAAGGGGA 
CCTGCCGGGC CCCCTGGCCG AGATGGCATC CCCGGACAGC CTGGACTTCC CGGACCCCCT 
GGACCTCCCG GACCCCCTGG ACCCCCTGGC CTCGGAGGAA ACTTTGCTCC CCAAATGTCT 
TATGGCTATG ATGAGAAATC AACTGGAGGA ATCTCCGTGC CTGGCCCCAT GGGTCCTTCT 
GGTCCTCGTG GTCTCCCTGG CCCCCCTGGC GCACCTGGTC CTCAAGGTTT CCAAGGCCCC 
CCTGGTGAAC CTGGCGAGCC TGGAGCCTCA GGTCCCATGG GTCCCCGTGG TCCCCCTGGC 
CCCCCTGGCA AGAACGGAGA TGACGGTGAA GCTGGAAAGC CTGGTCGTCC TGGTGAGCGT 
GGGCCTCCTG GGCCTCAGGG TGCTCGGGGA TTGCCTGGAA CAGCTGGCCT TCCTGGAATG 
AAGGGACACA GAGGTTTCAG TGGTTTGGAT GGTGCCAAGG GAGATGCTGG TCCTGCTGGT 
CCCAAGGGTG AGCCTGGTAG CCCCGGTGAA AATGGAGCTC CTGGCCAGAT GGGCCCCCGT 
GGTCTGCCCG GTGAAAGAGG TCGCCCTGGA GCCCCTGGCC CTGCCGGTGC TCGTGGAAAC 
GATGGTGCTA CTGGTGCTGC TGGGCCCCCT GGTCCCACTG GCCCCGCTGG TCCTCCTGGC 
TTCCCCGGTG CTGTTGGTGC TAAGGGTGAA GCTGGTCCCC AAGGAGCCCG TGGCTCTGAA 
GGTCCCCAGG GCGTGCGTGG TGAGCCCGGC CCCCCTGGCC CTGCTGGTGC TGCCGGCCCT 
GCCGGAAACC CCGGTGCTGA TGGACAGCCT GGTGCTAAAG GTGCTAACGG CGCTCCTGGC 
ATTGCTGGTG CTCCCGGCTT CCCCGGTGCC CGAGGCCCCT CTGGACCCCA GGGCCCCAGC 
GGTCCTCCTG GTCCCAAGGG TAACAGCGGT GAACCTGGTG CTCCCGGAAA CAAAGGAGAC 
ACTGGTGCCA AGGGAGAGCC CGGCCCCACT GGTATTCAAG GTCCCCCTGG CCCTGCTGGG 
GAAGAAGGAA AGCGAGGAGC CCGAGGTGAA CCTGGACCCA CTGGCCTGCC CGGACCCCCT 
GGCGAGCGTG GTGGACCTGG TAGCCGTGGT TTCCCTGGTG CAGATGGTGT CGCTGGTCCC 
AAGGGTCCCG CTGGTGAACG TGGTTCTCCT GGTCCCGCTG GGCCCAAAGG TTCTCCTGGT 
GAAGCTGGTC GCCCTGGTGA AGCTGGTCTG CCTGGTGCCA AGGGTCTGAC TGGAAGTCCT 
GGCAGCCCCG GTCCAGATGG CAAAACTGGC CCCCCTGGTC CCGCTGGTCA GGATGGTCGT 
CCCGGACCCC CAGGCCCCCC TGGTGCCCGT GGTCAAGCTG GTGTGATGGG ATTCCCTGGG 
CCTAAAGGTG CCGCTGGAGA GCCTGGCAAG GCTGGAGAGC GTGGTGTCCC TGGCCCCCCT 
GGTGCTGTTG GTCCTGCTGG CAAAGATGGA GAAGCAGGAG CTCAGGGGCC CCCTGGCCCT 
GCTGGCCCCG CTGGCGAGAG AGGTGAACAA GGTCCTGCTG GCTCCCCCGG ATTCCAGGGT 
CTCCCTGGCC CTGCTGGTCC TCCCGGCGAA GCAGGCAAAC CTGGTGAACA GGGTGTTCCT 
GGCGACCTTG GTGCCCCCGG CCCCTCTGGA GCAAGAGGCG AGAGAGGCTT TCCTGGTGAA 
CGTGGTGTGC AAGGTCCCCC CGGTCCTGCA GGTCCCCGAG GAGCCAACGG TGCCCCTGGC 
AATGATGGTG CTAAGGGTGA TGCTGGTGCC CCTGGAGCCC CAGGTAGCCA GGGCGCTCCT 
GGCCTTCAGG GAATGCCTGG TGAACGAGGT GCAGCTGGTC TTCCTGGCCC TAAGGGTGAC 
AGAGGTGATG CCGGTCCCAA AGGTGCTGAT GGTTCTCCTG GCAAAGATGG TGTCCGTGGT 
CTGACTGGCC CCATTGGTCC TCCTGGCCCT GCTGGTGCCC CTGGTGACAA GGGTGAAGCT 
GGTCCTAGCG GCCCTGCTGG TCCCACTGGA GCTCGTGGTG CCCCCGGAGA CCGTGGTGAG 
CCTGGTCCCC CTGGTCCTGC TGGCTTCGCT GGGCCCCCCG GTGCTGACGG CCAACCTGGT 
GCTAAAGGTG AACCCGGTGA TGCTGGTGCT AAAGGCGACG CTGGTCCCCC TGGCCCTGCT 
GGACCCACTG GACCTCCCGG CCCCATTGGT AACGTTGGTG CTCCTGGACC CAAAGGTGCT 
CGTGGCAGCG CCGGTCCCCC TGGTGCTACT GGTTTCCCTG GTGCTGCTGG CCGCGTCGGT 
CCCCCCGGCC CCTCTGGAAA TGCTGGACCC CCTGGCCCTC CTGGCCCTGC TGGCAAAGAA 
GGCGGCAAAG GCGCCCGTGG TGAGACTGGC CCTGCTGGAC GTCCCGGTGA AGTCGGTCCC 
CCTGGTCCCC CTGGCCCTGC TGGCGAGAAA GGATCCCCTG GTGCTGATGG ACCCGCTGGT 
GCTCCCGGCA CTCCCGGACC TCAAGGCATT GCTGGACAGC GTGGTGTGGT CGGTCTGCCC 
GGTCAACGAG GAGAAAGAGG CTTCCCTGGT CTTCCCGGCC CCTCTGGCGA ACCTGGCAAA 
CAAGGTCCTT CTGGAACAAG TGGTGAACGT GGTCCCCCTG GTCCCATGGG CCCCCCTGGA 
TTAGCTGGAC CCCCTGGCGA GTCTGGACGG GAGGGATCTC CTGGTGCTGA AGGCTCCCCT 
GGACGAGATG GTTCTCCTGG CCCCAAGGGT GACCGTGGTG AGACCGGCCC TGCTGGACCC 
CCTGGTGCCC CCGGTGCCCC TGGTGCTCCT GGCCCTGTCG GCCCTGCTGG CAAGAACGGT 
GACCGCGGTG AGACTGGTCC TGCTGGTCCT GCTGGCCCAA TCGGCCCTGT TGGTGCTCGT 
GGTCCTGCTG GACCCCAAGG CCCCCGTGGT GACAAGGGTG AGACAGGCGA ACAGGGTGAC 
AGAGGCATAA AGGGTCACCG TGGCTTCTCT GGTCTTCAGG GTCCTCCTGG CCCTCCCGGC 
TCTCCTGGTG AACAAGGTCC TTCTGGAGCT TCTGGTCCTG CTGGTCCCCG AGGTCCCCCT 
GGCTCTGCTG GTTCTCCTGG CAAAGACGGA CTCAACGGTC TCCCAGGCCC CATTGGCCCC 
CCCGGTCCTC GTGGTCGCAC TGGTGATGCC GGTCCTGTTG GTCCCCCTGG CCCTCCTGGA 
CCCCCTGGTC CCCCCGGTCC TCCCAGCGGC GGTTTCGACT TCAGCTTCCT GCCCCAGCCA 
CCTCAGGAGA AGGCTCACGA TGGCGGCCGC TACTACCGGG CCGATGATGC CAACGTGGTC 
CGTGACCGTG ACCTCGAGGT AGACACCACC CTCAAGAGCC TGAGCCAGCA GATCGAGAAC 
ATCCGGAGCC CTGAAGGAAG CCGCAAGAAC CCTGCCCGCA CCTGCCGCGA CCTCAAGATG 
TGCCACTCCG ACTGGAAGAG CGGAGAATAC TGGATTGACC CCAACCAAGG ATGCAACCTC 
GATGCCATCA AGGTTTTCTG CAACATGGAG ACAGGTGAGA CCTGCGTATA CCCCACTCAG 
CCCCAGGTGG CCCAGAAGAA CTGGTACATC AGCAAGAACC CCAAGGAGAA GAGACACGTC 
TGGTACGGCG AGAGCATGAC CGACGGATTC CAGTTCGAGT ATGGTGGCCA GGGCTCCGAT 
CCTGCCGATG TGGCCATCCA GCTGACCTTC CTGCGCCTGA TGTCCACCGA GGCCTCCCAG 
AACATCACCT ACCACTGCAA GAACAGCGTG GCCTACATGG ACCAGCAGAC CGGCAACCTC 
AAGAAGGCCC TGCTCCTCCA GGGTTCCAAC GAGATCGAGA TCCGGGCCGA GGGCAACAGC 
CGCTTCACCT ACAGTGTCAC CTACGACGGC TGCACGAGTC ACACTGGAGC CTGGGGCAAG 
ACAGTGATCG AATACAAAAC CACCAAGACC TCCCGTTTGC CCATCATCGA TGTGGCACCA 
TTGGACGTTG GCGCCCCAGA CCAGGAATTC GGCATGGATA TTGGCCCTGT CTGCTTCCTG 
TAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Chronic obstructive sleep apnea accelerates pulmonary remodeling via TGF-?/miR-185/CoLA1 signaling in a canine model.
Oncotarget7(36)57545-57555(2016 Sep)
Ding X,Yu C,Liu Y,Yan S,Li W,Wang D,Sun L,Han Y,Li M,Zhang S,Yun F,Zhao H,Li Y

The pH-dependent Client Release from the Collagen-specific Chaperone HSP47 Is Triggered by a Tandem Histidine Pair.
The Journal of biological chemistry291(24)12612-26(2016 Jun)
Oecal S,Socher E,Uthoff M,Ernst C,Zaucke F,Sticht H,Baumann U,Gebauer JM

Genetic basis of cranial cruciate ligament rupture (CCLR) in dogs.
Connective tissue research55(4)275-81(2014 Aug)
Baird AE,Carter SD,Innes JF,Ollier WE,Short AD

Synoviocyte neotissues towards in vitro meniscal tissue engineering.
Research in veterinary science95(3)1201-9(2013 Dec)
Warnock JJ,Duesterdieck-Zellmer KF,Bobe G,Baltzer WI,Ott J

Contributions of galectin-3 and -9 to epithelial cell adhesion analyzed by single cell force spectroscopy.
The Journal of biological chemistry282(40)29375-83(2007 Oct)
Friedrichs J,Torkko JM,Helenius J,Ter?v?inen TP,F?llekrug J,Muller DJ,Simons K,Manninen A

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COL1A1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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