PGR cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	PGR
Entrez Gene ID	403621
Full Name	progesterone receptor
Synonyms	PR
General protein information	Preferred Names progesterone receptor Names progesterone receptor nuclear receptor subfamily 3 group C member 3
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001003074.1	NP_001003074.1	progesterone receptor

Pathways from BioSystems

Homologies

Homo sapiens (human)	PGR	NP_000917.3
Bos taurus (cattle)	PGR	NP_001192285.1
	PGR	XP_002799839.1
Gallus gallus (chicken)	PGR	NP_990593.1
Mus musculus (house mouse)	Pgr	NP_032855.2
Pan troglodytes (chimpanzee)	PGR	NP_001129085.1
Canis lupus familiaris (dog)	PGR	NP_001003074.1
Rattus norvegicus (Norway rat)	Pgr	NP_074038.1

Gene Ontology
Bibliography

Related articles in PubMed

Marginal activity of progesterone receptor B (PR-B) in dogs but high incidence of mammary cancer.
Gracanin A, Voorwald FA, van Wolferen M, Timmermans-Sprang E, Mol JA
The Journal of steroid biochemistry and molecular biology144 Pt B492-9(2014 Oct)

Columnar cell lesions of the canine mammary gland: pathological features and immunophenotypic analysis.
Ferreira E, Gobbi H, Saraiva BS, Cassali GD
BMC cancer1061(2010 Feb)

Uterine progesterone receptor and leukaemia inhibitory factor mRNA expression in canine pregnancy.
Sch?fer-Somi S, Klein D, Beceriklisoy HB, Sabitzer S, Ay SS, Agaoglu AR, K?c?kaslan I, Kaya D, Aksoy OA, Aslan S
Reproduction in domestic animals = Zuchthygiene44 Suppl 2109-14(2009 Jul)

Oestrogen and progesterone receptor gene expression in canine oocytes and cumulus cells throughout the oestrous cycle.
Gon?alves JS, Vannucchi CI, Braga FC, Paula-Lopes FF, Milazzotto MP, Assump??o ME, Visintin JA
Reproduction in domestic animals = Zuchthygiene44 Suppl 2239-42(2009 Jul)

Comparison of steroid receptor expression in normal, dysplastic, and neoplastic canine and feline mammary tissues.
Millanta F, Calandrella M, Bari G, Niccolini M, Vannozzi I, Poli A
Research in veterinary science79(3)225-32(2005 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Marginal activity of progesterone receptor B in dogs but high incidence of mammary cancer
Title: Marginal activity of progesterone receptor B (PR-B) in dogs but high incidence of mammary cancer.

ER, PgR and E-cadherin are expressed in canine mammary gland columnar cell lesions; cytokeratin 34betaE-12, HER-2 and P53 are not expressed
Title: Columnar cell lesions of the canine mammary gland: pathological features and immunophenotypic analysis.

The roles of leukemia inhibitory factor and progesterone receptor expression on the establishment and maintenance of canine pregnancy are reported.
Title: Uterine progesterone receptor and leukaemia inhibitory factor mRNA expression in canine pregnancy.

It was found that canine oocytes express estrogen receptor alpha and estrogen receptor beta throughout the oestrous cycle, however, there is a lack of progesterone receptor expression in all these phases.
Title: Oestrogen and progesterone receptor gene expression in canine oocytes and cumulus cells throughout the oestrous cycle.

In bitches no significant variation in PR expression was observed between normal tissue, dysplasias, and benign neoplasms, but was significantly lower in mammary carcinomas
Title: Comparison of steroid receptor expression in normal, dysplastic, and neoplastic canine and feline mammary tissues.

The following PGR gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the PGR cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe00050	NM_001003074.1 Latest version!	Canis lupus familiaris progesterone receptor (PGR), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$510.30 $729.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

PGR ( NM_001003074.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001003074.1 Canis lupus familiaris progesterone receptor (PGR), mRNA.

Price & Availability↑

CloneID	OCe00050
Clone ID Related Accession (Same CDS sequence)	NM_001003074.1
Accession Version	NM_001003074.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2820bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Canis lupus familiaris(dog)
Product	progesterone receptor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF177470.1. ##Evidence-Data-START## Transcript exon combination :: AF177470.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547738, SAMEA4547739 [ECO:0000348] ##Evidence-Data-END##

ATGACGGAGC GGACGGGAAA GGATGCCCGG GCTCCCCACG TGGCGGGAGG CGCGCCCTCC 
CCCGCGCCGG CCGCAGAGCC CGAGTCCCGA CGTCGAGACG GCGGCCGCCT CCGGGCGAGT 
CAGACCTCGG ACGCCCCGCG GGTCGCCGCA GCCGCAGCCG CAGCCGCAGC CGCAGCCTCA 
GCCGCGCCCT CCGCGCCCTC GGACCGGCTG CTCTTCTCCC GGCGCGGCCA GGGCGCGGAC 
CCTGGCGGGA AGGCGCAGGA CGCGCAGCCG CGGCCGGACG TGGCCCGGGC GGATCCGAGA 
CTCGAAGCCG CGAGCGGGGC GGGAGCCGAC AGCCCCGGGC CCCCGCGCCA GGACCGAGGG 
CCGCTGCACG GCGCTCCGAG CACAGCGCTG CGCCCCGCCG GCCCGGGGCA GGGCCGCAGC 
TCTCCGGCCT GGGAGCCCCG CAGCCCGCGG TGCCCGTCTG GCCCCGAGCC GCCCGAAGAT 
CCCCGGGGCG CCCGCAGCAG CCAGGGCGCG GCGTGCCCGC TCATGAGCCG GCCGGAGGGC 
AAGGCTGGCG ACGGCTGCGG GACGGCAGGT GCCCACAAGG GGCCGCCCAG GGGCCTGTCC 
CCGTCCCGGC AGCCGCTGCC CCTGTGCCCC GGGGCCCACG CCTGGCCCGG GGCCGCGGGG 
AAAGCCGCCA CGCAGCCCGC TGCGCTGGGC GTGGAGGACG AGGGCGGCTT CGCGGCCGAG 
GGCTCCCCGG GCCCGCTCCT CAAGGGCAAG CCCCGGCCCC CCGCGGGCCC GGCGGCCGCA 
GCCGGCGCCG CTCCCGCTGC GCCGGGGACG GCCCCCGGGG GCACCGCCCC GGTCCCCAAG 
GAGGACTCCC GCCTCCCCGC GCCCAAGGGC TCCCTGGCCG AGCAGGACGC GCCGGCGCCC 
GGGTGCTCCC CGCTGGCCAC CACGATGATG GACTTTATCC ACGTGCCCAT TCTGCCCCTC 
GGCTCGGCCT TCCTGGCGGC GCGCACCCGG CAGCTGCTGG AAGCGGAGAC CTACGACGCC 
GGCGCCTTCG CTCCGCCGCG GGGCTCGCCC TCCGCGCCCT GCGCCCCGCT GGCGGCCGGC 
GACTTCCCCG ACTGTGCGTA CCCGTCCGAC GCCGAGCCCA AGGACGACGC GTTCCCGCTC 
TACGGCGACT TCCAGCCGCC GGCCCTGAAG ATCAAGGAGG AGGAGGAGGG CGCCGAGGCG 
GCTGCGCGCT CCCCGCGGCC GTACCTGGCG GCGGGGCCTC ACTCCTGCGT CTTCGCGGAC 
GCGCCGCCGG CGCTGCCGGC GCTGCCCCCG CTCCCCCCGC GAGCGCCGTC GTCCAGGCCC 
GGGGAAGGCG CGCCCGCGGC CGCCGCGGCC GCCGGCTGCT CCGCGTCGTC GGCGTCCTCG 
CCGGGGCCCG CCCTGGAGTG CGTCCTGTAC AAGGCGGAGG GCGCGCCGCC GCCGCAGGGC 
CCGTTCGCCG CCGCGCCCTG CAGGGTTCCG GGCGCCGGCG CCTGCCTGCT GCCCCGGGAC 
GGCGCGGCCG CCGCTGCCTC GGCGGGGGCC GCGGGGGCCA GCCCCGCGCT CTACCAGCCG 
CTCGGCCTCG GCGCCCTTCC GCAGCTCGGC TACCAGGCGG CCGTGCTCAA GGAGGGCTTG 
CCGCAGGTGT ACCAGCCGTA CCTCAACTAC CTGAGGCCTG ATTCAGATGC CAGCCAGAGC 
CCACAGTACA GCTTCGAGTC ATTACCTCAG AAGATTTGTT TAATCTGTGG GGATGAAGCA 
TCAGGCTGTC ATTATGGTGT CCTAACTTGT GGGAGCTGTA AGGTCTTCTT TAAAAGGGCA 
ATGGAAGGGC AGCATAACTA TTTATGTGCT GGAAGAAATG ACTGCATTGT TGATAAAATC 
CGCAGAAAAA ACTGCCCAGC ATGTCGCCTT AGAAAGTGCT GTCAGGCTGG CATGGTCCTT 
GGAGGTCGAA AATTTAAAAA GTTCAATAAA GTCAGAGTTA TGAGAACATT GGATGCTGTT 
GCTCTCCCAC AACCTGTGGG CATTCCAAAT GAAAGCCAAG CTCTAAGCCA AAGAATATCT 
TTTTCACCAA GTCAAGATAT ACAGTTAATT CCCCCATTGA TTAACCTGCT AATGAGCATT 
GAACCAGATG TGATCTATGC AGGACATGAC AACACCAAAC CTGATACCTC CAGTTCTTTG 
CTGACGAGTC TTAATCAACT AGGCGAGAGA CAACTTCTTT CAGTAGTCAA GTGGTCTAAA 
TCATTGCCAG GTTTTCGAAA TTTACACATT GATGACCAAA TAACTCTCAT CCAGTATTCT 
TGGATGAGCT TAATGGTGTT TGGACTAGGA TGGAGATCTT ACAAACATGT CAGTGGGCAG 
ATGCTATATT TTGCACCTGA TCTAATACTA AATGAACAGA GGATGAAGGA ATCATCATTC 
TATTCATTAT GCCTCACCAT GTGGCAGATC CCACAGGAGT TTGTCAAGCT TCAAGTTAGC 
CAGGAAGAGT TCCTGTGTAT GAAAGTATTG CTACTTCTTA ATACAATTCC TTTGGAAGGA 
CTAAGAAGTC AAAACCAGTT TGAAGAGATG AGATCAAGCT ACATTAGAGA GCTCATCAAA 
GCAATTGGCT TGAGGCAAAA AGGAGTTGTC TCTAGCTCAC AGCGTTTCTA CCAACTCACA 
AAACTTCTTG ATAACTTGCA TGATCTTGTC AAACAGCTTC ATCTGTACTG CTTGAATACA 
TTTATCCAGT CCCGGGCACT GAGTGTTGAG TTTCCAGAAA TGATGTCTGA AGTTATTGCC 
GCACAGTTAC CCAAGATCTT GGCAGGGATG GTGAAACCTC TGCTCTTTCA TAAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001003074.1
CDS	123..2942
Translation	MTERTGKDARAPHVAGGAPSPAPAAEPESRRRDGGRLRASQTSDAPRVAAAAAAAAAAASAAPSAPSDRLLFSRRGQGADPGGKAQDAQPRPDVARADPRLEAASGAGADSPGPPRQDRGPLHGAPSTALRPAGPGQGRSSPAWEPRSPRCPSGPEPPEDPRGARSSQGAACPLMSRPEGKAGDGCGTAGAHKGPPRGLSPSRQPLPLCPGAHAWPGAAGKAATQPAALGVEDEGGFAAEGSPGPLLKGKPRPPAGPAAAAGAAPAAPGTAPGGTAPVPKEDSRLPAPKGSLAEQDAPAPGCSPLATTMMDFIHVPILPLGSAFLAARTRQLLEAETYDAGAFAPPRGSPSAPCAPLAAGDFPDCAYPSDAEPKDDAFPLYGDFQPPALKIKEEEEGAEAAARSPRPYLAAGPHSCVFADAPPALPALPPLPPRAPSSRPGEGAPAAAAAAGCSASSASSPGPALECVLYKAEGAPPPQGPFAAAPCRVPGAGACLLPRDGAAAAASAGAAGASPALYQPLGLGALPQLGYQAAVLKEGLPQVYQPYLNYLRPDSDASQSPQYSFESLPQKICLICGDEASGCHYGVLTCGSCKVFFKRAMEGQHNYLCAGRNDCIVDKIRRKNCPACRLRKCCQAGMVLGGRKFKKFNKVRVMRTLDAVALPQPVGIPNESQALSQRISFSPSQDIQLIPPLINLLMSIEPDVIYAGHDNTKPDTSSSLLTSLNQLGERQLLSVVKWSKSLPGFRNLHIDDQITLIQYSWMSLMVFGLGWRSYKHVSGQMLYFAPDLILNEQRMKESSFYSLCLTMWQIPQEFVKLQVSQEEFLCMKVLLLLNTIPLEGLRSQNQFEEMRSSYIRELIKAIGLRQKGVVSSSQRFYQLTKLLDNLHDLVKQLHLYCLNTFIQSRALSVEFPEMMSEVIAAQLPKILAGMVKPLLFHKK

Target ORF information:

RefSeq Version	NM_001003074.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris progesterone receptor (PGR), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001003074.1

ORF Insert Sequence:

ATGACGGAGC GGACGGGAAA GGATGCCCGG GCTCCCCACG TGGCGGGAGG CGCGCCCTCC 
CCCGCGCCGG CCGCAGAGCC CGAGTCCCGA CGTCGAGACG GCGGCCGCCT CCGGGCGAGT 
CAGACCTCGG ACGCCCCGCG GGTCGCCGCA GCCGCAGCCG CAGCCGCAGC CGCAGCCTCA 
GCCGCGCCCT CCGCGCCCTC GGACCGGCTG CTCTTCTCCC GGCGCGGCCA GGGCGCGGAC 
CCTGGCGGGA AGGCGCAGGA CGCGCAGCCG CGGCCGGACG TGGCCCGGGC GGATCCGAGA 
CTCGAAGCCG CGAGCGGGGC GGGAGCCGAC AGCCCCGGGC CCCCGCGCCA GGACCGAGGG 
CCGCTGCACG GCGCTCCGAG CACAGCGCTG CGCCCCGCCG GCCCGGGGCA GGGCCGCAGC 
TCTCCGGCCT GGGAGCCCCG CAGCCCGCGG TGCCCGTCTG GCCCCGAGCC GCCCGAAGAT 
CCCCGGGGCG CCCGCAGCAG CCAGGGCGCG GCGTGCCCGC TCATGAGCCG GCCGGAGGGC 
AAGGCTGGCG ACGGCTGCGG GACGGCAGGT GCCCACAAGG GGCCGCCCAG GGGCCTGTCC 
CCGTCCCGGC AGCCGCTGCC CCTGTGCCCC GGGGCCCACG CCTGGCCCGG GGCCGCGGGG 
AAAGCCGCCA CGCAGCCCGC TGCGCTGGGC GTGGAGGACG AGGGCGGCTT CGCGGCCGAG 
GGCTCCCCGG GCCCGCTCCT CAAGGGCAAG CCCCGGCCCC CCGCGGGCCC GGCGGCCGCA 
GCCGGCGCCG CTCCCGCTGC GCCGGGGACG GCCCCCGGGG GCACCGCCCC GGTCCCCAAG 
GAGGACTCCC GCCTCCCCGC GCCCAAGGGC TCCCTGGCCG AGCAGGACGC GCCGGCGCCC 
GGGTGCTCCC CGCTGGCCAC CACGATGATG GACTTTATCC ACGTGCCCAT TCTGCCCCTC 
GGCTCGGCCT TCCTGGCGGC GCGCACCCGG CAGCTGCTGG AAGCGGAGAC CTACGACGCC 
GGCGCCTTCG CTCCGCCGCG GGGCTCGCCC TCCGCGCCCT GCGCCCCGCT GGCGGCCGGC 
GACTTCCCCG ACTGTGCGTA CCCGTCCGAC GCCGAGCCCA AGGACGACGC GTTCCCGCTC 
TACGGCGACT TCCAGCCGCC GGCCCTGAAG ATCAAGGAGG AGGAGGAGGG CGCCGAGGCG 
GCTGCGCGCT CCCCGCGGCC GTACCTGGCG GCGGGGCCTC ACTCCTGCGT CTTCGCGGAC 
GCGCCGCCGG CGCTGCCGGC GCTGCCCCCG CTCCCCCCGC GAGCGCCGTC GTCCAGGCCC 
GGGGAAGGCG CGCCCGCGGC CGCCGCGGCC GCCGGCTGCT CCGCGTCGTC GGCGTCCTCG 
CCGGGGCCCG CCCTGGAGTG CGTCCTGTAC AAGGCGGAGG GCGCGCCGCC GCCGCAGGGC 
CCGTTCGCCG CCGCGCCCTG CAGGGTTCCG GGCGCCGGCG CCTGCCTGCT GCCCCGGGAC 
GGCGCGGCCG CCGCTGCCTC GGCGGGGGCC GCGGGGGCCA GCCCCGCGCT CTACCAGCCG 
CTCGGCCTCG GCGCCCTTCC GCAGCTCGGC TACCAGGCGG CCGTGCTCAA GGAGGGCTTG 
CCGCAGGTGT ACCAGCCGTA CCTCAACTAC CTGAGGCCTG ATTCAGATGC CAGCCAGAGC 
CCACAGTACA GCTTCGAGTC ATTACCTCAG AAGATTTGTT TAATCTGTGG GGATGAAGCA 
TCAGGCTGTC ATTATGGTGT CCTAACTTGT GGGAGCTGTA AGGTCTTCTT TAAAAGGGCA 
ATGGAAGGGC AGCATAACTA TTTATGTGCT GGAAGAAATG ACTGCATTGT TGATAAAATC 
CGCAGAAAAA ACTGCCCAGC ATGTCGCCTT AGAAAGTGCT GTCAGGCTGG CATGGTCCTT 
GGAGGTCGAA AATTTAAAAA GTTCAATAAA GTCAGAGTTA TGAGAACATT GGATGCTGTT 
GCTCTCCCAC AACCTGTGGG CATTCCAAAT GAAAGCCAAG CTCTAAGCCA AAGAATATCT 
TTTTCACCAA GTCAAGATAT ACAGTTAATT CCCCCATTGA TTAACCTGCT AATGAGCATT 
GAACCAGATG TGATCTATGC AGGACATGAC AACACCAAAC CTGATACCTC CAGTTCTTTG 
CTGACGAGTC TTAATCAACT AGGCGAGAGA CAACTTCTTT CAGTAGTCAA GTGGTCTAAA 
TCATTGCCAG GTTTTCGAAA TTTACACATT GATGACCAAA TAACTCTCAT CCAGTATTCT 
TGGATGAGCT TAATGGTGTT TGGACTAGGA TGGAGATCTT ACAAACATGT CAGTGGGCAG 
ATGCTATATT TTGCACCTGA TCTAATACTA AATGAACAGA GGATGAAGGA ATCATCATTC 
TATTCATTAT GCCTCACCAT GTGGCAGATC CCACAGGAGT TTGTCAAGCT TCAAGTTAGC 
CAGGAAGAGT TCCTGTGTAT GAAAGTATTG CTACTTCTTA ATACAATTCC TTTGGAAGGA 
CTAAGAAGTC AAAACCAGTT TGAAGAGATG AGATCAAGCT ACATTAGAGA GCTCATCAAA 
GCAATTGGCT TGAGGCAAAA AGGAGTTGTC TCTAGCTCAC AGCGTTTCTA CCAACTCACA 
AAACTTCTTG ATAACTTGCA TGATCTTGTC AAACAGCTTC ATCTGTACTG CTTGAATACA 
TTTATCCAGT CCCGGGCACT GAGTGTTGAG TTTCCAGAAA TGATGTCTGA AGTTATTGCC 
GCACAGTTAC CCAAGATCTT GGCAGGGATG GTGAAACCTC TGCTCTTTCA TAAAAAGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Marginal activity of progesterone receptor B (PR-B) in dogs but high incidence of mammary cancer.
The Journal of steroid biochemistry and molecular biology144 Pt B492-9(2014 Oct)
Gracanin A,Voorwald FA,van Wolferen M,Timmermans-Sprang E,Mol JA

Columnar cell lesions of the canine mammary gland: pathological features and immunophenotypic analysis.
BMC cancer1061(2010 Feb)
Ferreira E,Gobbi H,Saraiva BS,Cassali GD

Uterine progesterone receptor and leukaemia inhibitory factor mRNA expression in canine pregnancy.
Reproduction in domestic animals = Zuchthygiene44 Suppl 2109-14(2009 Jul)
Sch?fer-Somi S,Klein D,Beceriklisoy HB,Sabitzer S,Ay SS,Agaoglu AR,K?c?kaslan I,Kaya D,Aksoy OA,Aslan S

Oestrogen and progesterone receptor gene expression in canine oocytes and cumulus cells throughout the oestrous cycle.
Reproduction in domestic animals = Zuchthygiene44 Suppl 2239-42(2009 Jul)
Gon?alves JS,Vannucchi CI,Braga FC,Paula-Lopes FF,Milazzotto MP,Assump??o ME,Visintin JA

Comparison of steroid receptor expression in normal, dysplastic, and neoplastic canine and feline mammary tissues.
Research in veterinary science79(3)225-32(2005 Dec)
Millanta F,Calandrella M,Bari G,Niccolini M,Vannozzi I,Poli A

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PGR cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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