Gene Symbol | DEFB122 |
Entrez Gene ID | 403504 |
Full Name | beta-defensin 122 |
Synonyms | CBD122,DEFB3L |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
ORF » Species Summary » Canis lupus familiaris » DEFB122 cDNA ORF clone
Gene Symbol | DEFB122 |
Entrez Gene ID | 403504 |
Full Name | beta-defensin 122 |
Synonyms | CBD122,DEFB3L |
Gene Type | protein-coding |
Organism | Canis lupus familiaris(dog) |
mRNA | Protein | Name |
---|---|---|
NM_001024641.2 | NP_001019812.2 | beta-defensin 122 isoform 1 precursor |
NM_001313788.1 | NP_001300717.1 | beta-defensin 122 isoform 2 precursor |
Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract.
Patil AA, Cai Y, Sang Y, Blecha F, Zhang G
Physiological genomics23(1)5-17(2005 Sep)
Molecular cloning and characterization of three beta-defensins from canine testes.
Sang Y, Ortega MT, Blecha F, Prakash O, Melgarejo T
Infection and immunity73(5)2611-20(2005 May)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
testicular tissue expression and broad antimicrobial activity suggest that canine beta-defensins play an important role in host defense and other physiological functions of the male reproductive system.[cBD-1, cBD-2, cBD-3]
Title: Molecular cloning and characterization of three beta-defensins from canine testes.
The following DEFB122 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DEFB122 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCe34338 | |
Clone ID Related Accession (Same CDS sequence) | NM_001024641.2 | |
Accession Version | NM_001024641.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 300bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-22 | |
Organism | Canis lupus familiaris(dog) | |
Product | beta-defensin 122 isoform 1 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03013870.1. On Sep 2, 2015 this sequence version replaced NM_001024641.1. Transcript Variant: This variant (cBD-3) encodes the longer isoform (1). Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: DQ011991.1, AY169792.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547738, SAMEA4547739 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGGCTT TTTTGCTGAC TTTGGCTGCG CTGGTGCTTT TGTCCCAGGT CACTTCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001019812.2 |
CDS | 133..432 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001024641.2 |
1 | ATGAAGGCTT TTTTGCTGAC TTTGGCTGCG CTGGTGCTTT TGTCCCAGGT CACTTCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCe45910 | |
Clone ID Related Accession (Same CDS sequence) | NM_001313788.1 | |
Accession Version | NM_001313788.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 198bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2017-10-22 | |
Organism | Canis lupus familiaris(dog) | |
Product | beta-defensin 122 isoform 2 precursor | |
Comment | Comment: VALIDATED REFSEQ: This record has undergone validation or preliminary review. The reference sequence was derived from AAEX03013870.1. Transcript Variant: This variant (cBD-1) differs in the 3' coding region and 3' UTR compared to variant cBD-3. The encoded isoform (2) has a distinct, shorter C-terminus than isoform 1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments. ##Evidence-Data-START## Transcript exon combination :: AY169790.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMEA4547738, SAMEA4547739 [ECO:0000348] ##Evidence-Data-END## |
1 | ATGAAGGCTT TTTTGCTGAC TTTGGCTGCG CTGGTGCTTT TGTCCCAGGT CACTTCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300717.1 |
CDS | 133..330 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001313788.1 |
1 | ATGAAGGCTT TTTTGCTGAC TTTGGCTGCG CTGGTGCTTT TGTCCCAGGT CACTTCAGGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Cross-species analysis of the mammalian beta-defensin gene family: presence of syntenic gene clusters and preferential expression in the male reproductive tract. |
Molecular cloning and characterization of three beta-defensins from canine testes. |