ABCC1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene
Clones
gRNAs

Summary

Gene Symbol	ABCC1
Entrez Gene ID	403453
Full Name	ATP binding cassette subfamily C member 1
Synonyms	MRP1
Gene Type	protein-coding
Organism	Canis lupus familiaris(dog)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001002971.1	NP_001002971.1	multidrug resistance-associated protein 1

Pathways from BioSystems

Homologies

Danio rerio (zebrafish)	abcc1	XP_001341895.3
Caenorhabditis elegans (roundworm)	mrp-1	NP_001033553.1
Arabidopsis thaliana (thale cress)	MRP5	NP_171908.1
Oryza sativa (rice)	Os03g0142800	NP_001048934.1
Canis lupus familiaris (dog)	ABCC1	NP_001002971.1
Bos taurus (cattle)	ABCC1	NP_776648.1
Homo sapiens (human)	ABCC1	NP_004987.2
Pan troglodytes (chimpanzee)	ABCC1	XP_001145351.1
Rattus norvegicus (Norway rat)	Abcc1	NP_071617.2
Gallus gallus (chicken)	ABCC1	NP_001012540.1
Mus musculus (house mouse)	Abcc1	NP_032602.1
Caenorhabditis elegans (roundworm)	mrp-2	NP_508121.1

Gene Ontology
Bibliography

Related articles in PubMed

Externalization of phosphatidylserine via multidrug resistance 1 (MDR1)/P-glycoprotein in oxalate-treated renal epithelial cells: implications for calcium oxalate urolithiasis.
Li YH, Yu SL, Gan XG, Pan SH, Teng YQ, An RH
International urology and nephrology48(2)175-81(2016 Feb)

Expression and role of PGP, BCRP, MRP1 and MRP3 in multidrug resistance of canine mammary cancer cells.
Paw?owski KM, Mucha J, Majchrzak K, Motyl T, Kr?l M
BMC veterinary research9119(2013 Jun)

ABC transporters in the eyes of dogs and implications in drug therapy.
Haritova AM, Krastev SZ, Santos RR, Schrickx JA, Fink-Gremmels J
Current eye research38(2)271-7(2013 Feb)

Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region.
Westlake CJ, Payen L, Gao M, Cole SP, Deeley RG
The Journal of biological chemistry279(51)53571-83(2004 Dec)

Identification and characterization of the canine multidrug resistance-associated protein.
Ma L, Pratt SE, Cao J, Dantzig AH, Moore RE, Slapak CA
Molecular cancer therapeutics1(14)1335-42(2002 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

oxalate increases the synthesis of MDR1 P-gp, which plays a key role in hyperoxaluria-promoted calcium oxalate urolithiasis by facilitating phosphatidylserine redistribution in renal epithelial cells.
Title: Externalization of phosphatidylserine via multidrug resistance 1 (MDR1)/P-glycoprotein in oxalate-treated renal epithelial cells: implications for calcium oxalate urolithiasis.

expression and role in multidrug resistance of mammary cancer cells
Title: Expression and role of PGP, BCRP, MRP1 and MRP3 in multidrug resistance of canine mammary cancer cells.

ABCC1, ABCC3 and ABCC4 are expressed predominantly in the conjunctiva and at very low levels in the cornea.
Title: ABC transporters in the eyes of dogs and implications in drug therapy.

the multidrug resistance protein 1 COOH-terminal region has elements with five conserved hydrophobic amino acids that are required for activity
Title: Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region.

The following ABCC1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ABCC1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OCe00060	NM_001002971.1 Latest version!	Canis lupus familiaris ATP binding cassette subfamily C member 1 (ABCC1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	25	$881.30 $1259.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ABCC1 ( NM_001002971.1 ) cDNA ORF clone, Canis lupus familiaris(dog) -> NP_001002971.1 Canis lupus familiaris ATP binding cassette subfamily C member 1 (ABCC1), mRNA.

Price & Availability↑

CloneID	OCe00060
Clone ID Related Accession (Same CDS sequence)	NM_001002971.1
Accession Version	NM_001002971.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 4596bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-25
Organism	Canis lupus familiaris(dog)
Product	multidrug resistance-associated protein 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY363728.1. ##Evidence-Data-START## Transcript exon combination :: AY363728.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMEA103936001, SAMEA103936002 [ECO:0000350] ##Evidence-Data-END##

ATGGCGCTCC GCGGCTTCTG CAGCGCCGAC GGCTCCGACC CCTTCTGGGA GTGGGATGTC 
TCGTGGAATA CCAGCAACCC CGACTTCACC AAGTGCTTTC AGAACACGGT CCTCGTGTGG 
GTGCCTTGTT GTTACCTCTG GCTCTGCTTC CCCTTCTACT TCCTCTATCT CTCGCGCCAT 
GACCGAGGCT ACATTCAGAT GACATATCTC AATAAAACCA AAACTGCCTT GGGATTTGTG 
CTATGGATCG TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TTGGGGCAAA 
ATCCTGGCCC CGGTGTTTCT GGTCAGCCCA ACCCTCTTGG GCATCACTAT GCTGCTTGCT 
ACCTTTTTAA TTCAGCTCGA GAGAAGGAAG GGAGTCCAGT CCTCGGGGAT CATGCTCACT 
TTCTGGCTTA TAGCCCTACT GTGTGCCCTT GCCATCTTGA GATCCAAAAT CATGACTGCC 
TTAAAAGAGG ATGCTGAAAT CGACGTGTTT CGTGATGTCA CTTTCTACAT TTACTTTTCC 
CTCGTGCTGA TTCAGCTCGT GTTGTCCTGC TTCTCAGACC GACCGCCCCT GTTCTCTGAA 
ACCATCCATG ACCTCAATCC CTGCCCGGAG TCCAGTGCCT CTTTCCTTTC CAGAGTCACC 
TTCTGGTGGA TCACAGGGTT GATGGTCCGA GGCTACCGCC AGCCCCTGGA AAGCACTGAC 
CTTTGGTCCC TGAATAAGGA GGACACGTCA GAACAAGTGG TGCCTGTTCT GGTAAAGAAC 
TGGAAGAAGG AGTGTGCCAA ATCCAAAAGA CAGCAGAGGA AGATCACATA CTCCTCCAAG 
GATCCTGCCA AGCCAAAAGG GGGCTCCCAG GTGGACGTGA ACGAGGAGGC TGAGGTGTTG 
ATTGTTAAGA CCCCACAGAA GGAGCGCGAG CCGTCTCTAT TCAAGGTGTT ATACAAGACC 
TTCGGGCCCT ACTTCCTCAT GAGCTTCTTA TTCAAGGCCC TCCATGACCT GATGATGTTT 
GCTGGCCCAG AGATCTTAAA GTTGCTCATC AACTTCGTGA ACGACAAGAA GGCCCCGGAC 
TGGCAGGGCT ACCTGTACAC TGCGCTGCTC TTCATCTGCG CCTGCCTGCA GACCCTCGTG 
CTGCACCAGT ACTTCCACAT CTGCTTCGTC AGCGGCATGA GGATCAAGAC AGCCGTCATC 
GGGGCCGTGT ACCGGAAGGC ATTGGTGATC ACCAACTCAG CCAGAAAATC CTCCACCGTC 
GGGGAGATTG TAAACCTCAT GTCTGTGGAC GCCCAGCGGT TCATGGACCT GGCCACGTAC 
ATTAACATGA TCTGGTCAGC TCCTCTGCAA GTCATCCTTG CTCTCTACCT CCTGTGGCTG 
AACCTGGGCC CGTCTGTCCT GGCTGGGGTG GCTGTGATGA TCCTCATGGT TCCGCTCAAT 
GCCGTGATGG CCATGAAGAC TAAGACCTAC CAGGTGGCGC ACATGAAGAG CAAAGACAAC 
CGGATCAAGC TGATGAATGA GATTCTCAAC GGGATCAAAG TGCTAAAGCT GTACGCCTGG 
GAACTGGCCT TCAAAGACAA AGTCCTGGCC ATCAGGCAGG AGGAGCTCAA GGTGCTGAAG 
AAATCGGCCT ACCTGGCCGC CGTGGGGACC TTCACCTGGG TCTGCACGCC ATTTCTGGTG 
GCCTTGTCTA CATTTGCTGT CTACGTGACC GTCGACAAGA ACAACATCCT CGACGCCCAG 
AAAGCTTTCG TGTCCTTGGC CTTGTTCAAC ATCCTCCGGT TCCCTCTGAA TATTCTCCCC 
ATGGTCATCA GCAGCATCGT GCAGGCAAGT GTCTCCCTCA AACGCCTCCG GATCTTCCTG 
TCTCACGAGG AGCTAGAGCC TGACAGCATT GAGCGAAGGC CCGTCAAAGA CGGCGGGGGC 
GCCAACAGCA TCACTGTGAA GAATGCCACG TTCACGTGGG CCCGGAGCGA CCCTCCAACG 
CTAAGCGGCA TCACCTTCTC CATTCCGGAA GGTTCCTTGG TGGCCGTGGT GGGCCAGGTG 
GGCTGCGGAA AGTCGTCTCT GCTCTCGGCA CTCCTGGCGG AGATGGACAA GGTGGAGGGG 
CATGTGGCTA TCAAGGGCTC AGTGGCCTAC GTCCCCCAGC AGGCCTGGAT TCAGAATGAT 
TCTCTCCGAG AAAACATCCT TTTCGGACGC CAGCTACAGG AACGGTATTA TAAGGCTGTG 
ATTGAAGCCT GTGCCCTCCT CCCAGATCTG GAAATCCTGC CCAGCGGGGA CCGGACAGAG 
ATTGGTGAGA AGGGCGTGAA CCTGTCTGGG GGCCAGAAGC AGCGAGTGAG CCTGGCGCGG 
GCCGTGTACT GTGACTCTGA CATCTACCTC TTCGATGATC CTCTGTCAGC AGTGGATGCT 
CATGTGGGAA AACACATATT TGAAAATGTG ATTGGCCCCA AGGGGATGCT AAAGAATAAG 
ACGCGGCTCC TGGTCACGCA CAGCATCAGT TACCTGCCCC AGGTGGATGT CATCATTGTC 
ATGACCGGTG GCAAGATCTC GGAGATGGGC TCCTACCAGG AGCTGCTGGC CCGGGATGGA 
GCCTTCGCCG AATTCCTTCG CACGTACGCC AGCGGCGATC AGGAGCAGGC CGAGCAGGAT 
GACGGGTTAA CAGGTGTCAG CAGTCCCGGG AAGGAGGTGA AGCAGATGGA GAATGGCATG 
CTGGTGACGG ATGTGGCGGG GAAGCAGCTG CAGAGACAGC TCAGCAACTC CTCCTCCTAC 
AGCGGGGACG TGAGCCGCCA CCACACCAGC ACGGCTGAGC TGCAGAAAGC CGGTCCCAAG 
AATGAGGACG CCTGGAAGCT GGTGGAAGCA GACAAGGCTC AAACGGGGCA GGTCAAGCTG 
TCCGTGTACT GGGACTACAT GAAGGCGATC GGGCTTTTCA TCTCCTTTCT GAGCATCTTC 
CTTTTCCTGT GTAACCACGT TGCCTCCCTG GTCTCGAACT ACTGGCTCAG CCTCTGGACC 
GACGACCCCA TCGTCAACGG GACCCAGGAG CATACTAAAA TCCGGCTGAG CGTCTATGGA 
GCCCTGGGCA TTTCGCAAGG TATCACGGTG TTCGGCTACT CCATGGCGGT GTCCATCGGG 
GGGATCTTCG CTTCCCGCCG CCTGCACGTC GACCTGCTAC AGAACGTCCT CCGGTCCCCC 
ATGAGCTTCT TCGAGCGGAC CCCCAGTGGG AACCTGGTGA ACCGCTTCTC TAAGGAGCTG 
GACACGGTGG ACTCGATGAT CCCACAAGTC ATCAAGATGT TCATGGGCTC CCTGTTCAAT 
GTCATCGGCG CCTGCATCAT CATCCTGCTG GCCACTCCCA TCGCCTCCAT CATCATCCCA 
CCACTAGGCC TCATCTATTT CTTTGTGCAG AGGTTTTACG TGGCCTCCTC CCGGCAGCTG 
AAGCGCCTCG AGTCGGTCAG CCGCTCCCCG GTGTACTCCC ACTTCAATGA GACCTTGCTG 
GGGGTCAGCG TCATCCGTGC CTTCGAGGAG CAGGAGCGCT TCATCCGCCA GAGTGACCTG 
AAGGTGGACG AGAACCAGAA GGCCTATTAC CCCAGCATCG TGGCCAACAG GTGGCTGGCC 
GTGCGGCTGG AGTGTGTAGG CAACTGCATC GTCCTGTTCG CTGCCCTGTT CTCCGTGATC 
TCCAGGCACA GTCTCAGCGC TGGCTTGGTG GGCCTGTCCG TGTCCTACTC CCTGCAGGTC 
ACCACGTACT TGAACTGGCT GGTTCGCATG TCATCCGAGA TGGAGACCAA CATCGTGGCC 
GTGGAGAGGC TGAAGGAGTA TTCAGAAACG GAGAAAGAGG CTCCCTGGCA AATCCAGGAG 
ATGGCTCCGC CCAGCACCTG GCCTCAGGTG GGCCGAGTGG AATTCCGGGA CTACGGCCTC 
CGCTACCGAG AAAACCTGGA CTTGGTTCTC AAGCACATCA ACATCACCAT CAACGGAGGG 
GAAAAGGTGG GCATCGTGGG GCGGACGGGA GCTGGGAAGT CGTCCCTGAC CCTGGGCTTG 
TTTCGGATCA ATGAGTCTGC CGAGGGGGAG ATCATTATCG ACGATATCAA TATTGCCAAG 
ATCGGCCTGC ATGACCTGCG CGTCAAGATC ACCATCATCC CGCAGGACCC TGTGTTGTTC 
TCGGGTTCGC TCCGCATGAA CCTGGACCCA TTCAGCCAGT ACTCAGACGA AGAAGTCTGG 
ACGTCCCTGG AGCTGGCTCA CCTGAAGGAC TTCGTGTCAG GCCTTCCCGA TAAGCTGAAC 
CAAGAGTGTG CAGAGGGCGG GGAGAACCTG AGCGTCGGGC AGCGCCAGCT CGTGTGCCTG 
GCCCGGGCTC TGCTGAGGAA AACCAAGATC CTCGTGTTGG ACGAGGCCAC GGCGGCCGTA 
GACCTAGAAA CCGATGACCT CATTCAGTCT ACCATCCGGA CGCAGTTTGA CGACTGCACC 
GTCCTCACCA TCGCGCACCG CCTCAACACC ATCATGGACT ACACAAGGGT GATCGTCCTG 
GACAAGGGAG AGATCCGAGA GTGCGGCCAG CCCTCCGACC TCCTACAGCA GAGAGGTCTC 
TTCTACAGCA TGGCCAAAGA TGCTGGCCTG GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002971.1
CDS	9..4604
Translation	MALRGFCSADGSDPFWEWDVSWNTSNPDFTKCFQNTVLVWVPCCYLWLCFPFYFLYLSRHDRGYIQMTYLNKTKTALGFVLWIVCWADLFYSFWERSWGKILAPVFLVSPTLLGITMLLATFLIQLERRKGVQSSGIMLTFWLIALLCALAILRSKIMTALKEDAEIDVFRDVTFYIYFSLVLIQLVLSCFSDRPPLFSETIHDLNPCPESSASFLSRVTFWWITGLMVRGYRQPLESTDLWSLNKEDTSEQVVPVLVKNWKKECAKSKRQQRKITYSSKDPAKPKGGSQVDVNEEAEVLIVKTPQKEREPSLFKVLYKTFGPYFLMSFLFKALHDLMMFAGPEILKLLINFVNDKKAPDWQGYLYTALLFICACLQTLVLHQYFHICFVSGMRIKTAVIGAVYRKALVITNSARKSSTVGEIVNLMSVDAQRFMDLATYINMIWSAPLQVILALYLLWLNLGPSVLAGVAVMILMVPLNAVMAMKTKTYQVAHMKSKDNRIKLMNEILNGIKVLKLYAWELAFKDKVLAIRQEELKVLKKSAYLAAVGTFTWVCTPFLVALSTFAVYVTVDKNNILDAQKAFVSLALFNILRFPLNILPMVISSIVQASVSLKRLRIFLSHEELEPDSIERRPVKDGGGANSITVKNATFTWARSDPPTLSGITFSIPEGSLVAVVGQVGCGKSSLLSALLAEMDKVEGHVAIKGSVAYVPQQAWIQNDSLRENILFGRQLQERYYKAVIEACALLPDLEILPSGDRTEIGEKGVNLSGGQKQRVSLARAVYCDSDIYLFDDPLSAVDAHVGKHIFENVIGPKGMLKNKTRLLVTHSISYLPQVDVIIVMTGGKISEMGSYQELLARDGAFAEFLRTYASGDQEQAEQDDGLTGVSSPGKEVKQMENGMLVTDVAGKQLQRQLSNSSSYSGDVSRHHTSTAELQKAGPKNEDAWKLVEADKAQTGQVKLSVYWDYMKAIGLFISFLSIFLFLCNHVASLVSNYWLSLWTDDPIVNGTQEHTKIRLSVYGALGISQGITVFGYSMAVSIGGIFASRRLHVDLLQNVLRSPMSFFERTPSGNLVNRFSKELDTVDSMIPQVIKMFMGSLFNVIGACIIILLATPIASIIIPPLGLIYFFVQRFYVASSRQLKRLESVSRSPVYSHFNETLLGVSVIRAFEEQERFIRQSDLKVDENQKAYYPSIVANRWLAVRLECVGNCIVLFAALFSVISRHSLSAGLVGLSVSYSLQVTTYLNWLVRMSSEMETNIVAVERLKEYSETEKEAPWQIQEMAPPSTWPQVGRVEFRDYGLRYRENLDLVLKHINITINGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDDINIAKIGLHDLRVKITIIPQDPVLFSGSLRMNLDPFSQYSDEEVWTSLELAHLKDFVSGLPDKLNQECAEGGENLSVGQRQLVCLARALLRKTKILVLDEATAAVDLETDDLIQSTIRTQFDDCTVLTIAHRLNTIMDYTRVIVLDKGEIRECGQPSDLLQQRGLFYSMAKDAGLV

Target ORF information:

RefSeq Version	NM_001002971.1
Organism	Canis lupus familiaris(dog)
Definition	Canis lupus familiaris ATP binding cassette subfamily C member 1 (ABCC1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002971.1

ORF Insert Sequence:

ATGGCGCTCC GCGGCTTCTG CAGCGCCGAC GGCTCCGACC CCTTCTGGGA GTGGGATGTC 
TCGTGGAATA CCAGCAACCC CGACTTCACC AAGTGCTTTC AGAACACGGT CCTCGTGTGG 
GTGCCTTGTT GTTACCTCTG GCTCTGCTTC CCCTTCTACT TCCTCTATCT CTCGCGCCAT 
GACCGAGGCT ACATTCAGAT GACATATCTC AATAAAACCA AAACTGCCTT GGGATTTGTG 
CTATGGATCG TCTGCTGGGC AGACCTCTTC TACTCTTTCT GGGAAAGAAG TTGGGGCAAA 
ATCCTGGCCC CGGTGTTTCT GGTCAGCCCA ACCCTCTTGG GCATCACTAT GCTGCTTGCT 
ACCTTTTTAA TTCAGCTCGA GAGAAGGAAG GGAGTCCAGT CCTCGGGGAT CATGCTCACT 
TTCTGGCTTA TAGCCCTACT GTGTGCCCTT GCCATCTTGA GATCCAAAAT CATGACTGCC 
TTAAAAGAGG ATGCTGAAAT CGACGTGTTT CGTGATGTCA CTTTCTACAT TTACTTTTCC 
CTCGTGCTGA TTCAGCTCGT GTTGTCCTGC TTCTCAGACC GACCGCCCCT GTTCTCTGAA 
ACCATCCATG ACCTCAATCC CTGCCCGGAG TCCAGTGCCT CTTTCCTTTC CAGAGTCACC 
TTCTGGTGGA TCACAGGGTT GATGGTCCGA GGCTACCGCC AGCCCCTGGA AAGCACTGAC 
CTTTGGTCCC TGAATAAGGA GGACACGTCA GAACAAGTGG TGCCTGTTCT GGTAAAGAAC 
TGGAAGAAGG AGTGTGCCAA ATCCAAAAGA CAGCAGAGGA AGATCACATA CTCCTCCAAG 
GATCCTGCCA AGCCAAAAGG GGGCTCCCAG GTGGACGTGA ACGAGGAGGC TGAGGTGTTG 
ATTGTTAAGA CCCCACAGAA GGAGCGCGAG CCGTCTCTAT TCAAGGTGTT ATACAAGACC 
TTCGGGCCCT ACTTCCTCAT GAGCTTCTTA TTCAAGGCCC TCCATGACCT GATGATGTTT 
GCTGGCCCAG AGATCTTAAA GTTGCTCATC AACTTCGTGA ACGACAAGAA GGCCCCGGAC 
TGGCAGGGCT ACCTGTACAC TGCGCTGCTC TTCATCTGCG CCTGCCTGCA GACCCTCGTG 
CTGCACCAGT ACTTCCACAT CTGCTTCGTC AGCGGCATGA GGATCAAGAC AGCCGTCATC 
GGGGCCGTGT ACCGGAAGGC ATTGGTGATC ACCAACTCAG CCAGAAAATC CTCCACCGTC 
GGGGAGATTG TAAACCTCAT GTCTGTGGAC GCCCAGCGGT TCATGGACCT GGCCACGTAC 
ATTAACATGA TCTGGTCAGC TCCTCTGCAA GTCATCCTTG CTCTCTACCT CCTGTGGCTG 
AACCTGGGCC CGTCTGTCCT GGCTGGGGTG GCTGTGATGA TCCTCATGGT TCCGCTCAAT 
GCCGTGATGG CCATGAAGAC TAAGACCTAC CAGGTGGCGC ACATGAAGAG CAAAGACAAC 
CGGATCAAGC TGATGAATGA GATTCTCAAC GGGATCAAAG TGCTAAAGCT GTACGCCTGG 
GAACTGGCCT TCAAAGACAA AGTCCTGGCC ATCAGGCAGG AGGAGCTCAA GGTGCTGAAG 
AAATCGGCCT ACCTGGCCGC CGTGGGGACC TTCACCTGGG TCTGCACGCC ATTTCTGGTG 
GCCTTGTCTA CATTTGCTGT CTACGTGACC GTCGACAAGA ACAACATCCT CGACGCCCAG 
AAAGCTTTCG TGTCCTTGGC CTTGTTCAAC ATCCTCCGGT TCCCTCTGAA TATTCTCCCC 
ATGGTCATCA GCAGCATCGT GCAGGCAAGT GTCTCCCTCA AACGCCTCCG GATCTTCCTG 
TCTCACGAGG AGCTAGAGCC TGACAGCATT GAGCGAAGGC CCGTCAAAGA CGGCGGGGGC 
GCCAACAGCA TCACTGTGAA GAATGCCACG TTCACGTGGG CCCGGAGCGA CCCTCCAACG 
CTAAGCGGCA TCACCTTCTC CATTCCGGAA GGTTCCTTGG TGGCCGTGGT GGGCCAGGTG 
GGCTGCGGAA AGTCGTCTCT GCTCTCGGCA CTCCTGGCGG AGATGGACAA GGTGGAGGGG 
CATGTGGCTA TCAAGGGCTC AGTGGCCTAC GTCCCCCAGC AGGCCTGGAT TCAGAATGAT 
TCTCTCCGAG AAAACATCCT TTTCGGACGC CAGCTACAGG AACGGTATTA TAAGGCTGTG 
ATTGAAGCCT GTGCCCTCCT CCCAGATCTG GAAATCCTGC CCAGCGGGGA CCGGACAGAG 
ATTGGTGAGA AGGGCGTGAA CCTGTCTGGG GGCCAGAAGC AGCGAGTGAG CCTGGCGCGG 
GCCGTGTACT GTGACTCTGA CATCTACCTC TTCGATGATC CTCTGTCAGC AGTGGATGCT 
CATGTGGGAA AACACATATT TGAAAATGTG ATTGGCCCCA AGGGGATGCT AAAGAATAAG 
ACGCGGCTCC TGGTCACGCA CAGCATCAGT TACCTGCCCC AGGTGGATGT CATCATTGTC 
ATGACCGGTG GCAAGATCTC GGAGATGGGC TCCTACCAGG AGCTGCTGGC CCGGGATGGA 
GCCTTCGCCG AATTCCTTCG CACGTACGCC AGCGGCGATC AGGAGCAGGC CGAGCAGGAT 
GACGGGTTAA CAGGTGTCAG CAGTCCCGGG AAGGAGGTGA AGCAGATGGA GAATGGCATG 
CTGGTGACGG ATGTGGCGGG GAAGCAGCTG CAGAGACAGC TCAGCAACTC CTCCTCCTAC 
AGCGGGGACG TGAGCCGCCA CCACACCAGC ACGGCTGAGC TGCAGAAAGC CGGTCCCAAG 
AATGAGGACG CCTGGAAGCT GGTGGAAGCA GACAAGGCTC AAACGGGGCA GGTCAAGCTG 
TCCGTGTACT GGGACTACAT GAAGGCGATC GGGCTTTTCA TCTCCTTTCT GAGCATCTTC 
CTTTTCCTGT GTAACCACGT TGCCTCCCTG GTCTCGAACT ACTGGCTCAG CCTCTGGACC 
GACGACCCCA TCGTCAACGG GACCCAGGAG CATACTAAAA TCCGGCTGAG CGTCTATGGA 
GCCCTGGGCA TTTCGCAAGG TATCACGGTG TTCGGCTACT CCATGGCGGT GTCCATCGGG 
GGGATCTTCG CTTCCCGCCG CCTGCACGTC GACCTGCTAC AGAACGTCCT CCGGTCCCCC 
ATGAGCTTCT TCGAGCGGAC CCCCAGTGGG AACCTGGTGA ACCGCTTCTC TAAGGAGCTG 
GACACGGTGG ACTCGATGAT CCCACAAGTC ATCAAGATGT TCATGGGCTC CCTGTTCAAT 
GTCATCGGCG CCTGCATCAT CATCCTGCTG GCCACTCCCA TCGCCTCCAT CATCATCCCA 
CCACTAGGCC TCATCTATTT CTTTGTGCAG AGGTTTTACG TGGCCTCCTC CCGGCAGCTG 
AAGCGCCTCG AGTCGGTCAG CCGCTCCCCG GTGTACTCCC ACTTCAATGA GACCTTGCTG 
GGGGTCAGCG TCATCCGTGC CTTCGAGGAG CAGGAGCGCT TCATCCGCCA GAGTGACCTG 
AAGGTGGACG AGAACCAGAA GGCCTATTAC CCCAGCATCG TGGCCAACAG GTGGCTGGCC 
GTGCGGCTGG AGTGTGTAGG CAACTGCATC GTCCTGTTCG CTGCCCTGTT CTCCGTGATC 
TCCAGGCACA GTCTCAGCGC TGGCTTGGTG GGCCTGTCCG TGTCCTACTC CCTGCAGGTC 
ACCACGTACT TGAACTGGCT GGTTCGCATG TCATCCGAGA TGGAGACCAA CATCGTGGCC 
GTGGAGAGGC TGAAGGAGTA TTCAGAAACG GAGAAAGAGG CTCCCTGGCA AATCCAGGAG 
ATGGCTCCGC CCAGCACCTG GCCTCAGGTG GGCCGAGTGG AATTCCGGGA CTACGGCCTC 
CGCTACCGAG AAAACCTGGA CTTGGTTCTC AAGCACATCA ACATCACCAT CAACGGAGGG 
GAAAAGGTGG GCATCGTGGG GCGGACGGGA GCTGGGAAGT CGTCCCTGAC CCTGGGCTTG 
TTTCGGATCA ATGAGTCTGC CGAGGGGGAG ATCATTATCG ACGATATCAA TATTGCCAAG 
ATCGGCCTGC ATGACCTGCG CGTCAAGATC ACCATCATCC CGCAGGACCC TGTGTTGTTC 
TCGGGTTCGC TCCGCATGAA CCTGGACCCA TTCAGCCAGT ACTCAGACGA AGAAGTCTGG 
ACGTCCCTGG AGCTGGCTCA CCTGAAGGAC TTCGTGTCAG GCCTTCCCGA TAAGCTGAAC 
CAAGAGTGTG CAGAGGGCGG GGAGAACCTG AGCGTCGGGC AGCGCCAGCT CGTGTGCCTG 
GCCCGGGCTC TGCTGAGGAA AACCAAGATC CTCGTGTTGG ACGAGGCCAC GGCGGCCGTA 
GACCTAGAAA CCGATGACCT CATTCAGTCT ACCATCCGGA CGCAGTTTGA CGACTGCACC 
GTCCTCACCA TCGCGCACCG CCTCAACACC ATCATGGACT ACACAAGGGT GATCGTCCTG 
GACAAGGGAG AGATCCGAGA GTGCGGCCAG CCCTCCGACC TCCTACAGCA GAGAGGTCTC 
TTCTACAGCA TGGCCAAAGA TGCTGGCCTG GTGTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Externalization of phosphatidylserine via multidrug resistance 1 (MDR1)/P-glycoprotein in oxalate-treated renal epithelial cells: implications for calcium oxalate urolithiasis.
International urology and nephrology48(2)175-81(2016 Feb)
Li YH,Yu SL,Gan XG,Pan SH,Teng YQ,An RH

Expression and role of PGP, BCRP, MRP1 and MRP3 in multidrug resistance of canine mammary cancer cells.
BMC veterinary research9119(2013 Jun)
Paw?owski KM,Mucha J,Majchrzak K,Motyl T,Kr?l M

ABC transporters in the eyes of dogs and implications in drug therapy.
Current eye research38(2)271-7(2013 Feb)
Haritova AM,Krastev SZ,Santos RR,Schrickx JA,Fink-Gremmels J

Identification and characterization of functionally important elements in the multidrug resistance protein 1 COOH-terminal region.
The Journal of biological chemistry279(51)53571-83(2004 Dec)
Westlake CJ,Payen L,Gao M,Cole SP,Deeley RG

Identification and characterization of the canine multidrug resistance-associated protein.
Molecular cancer therapeutics1(14)1335-42(2002 Dec)
Ma L,Pratt SE,Cao J,Dantzig AH,Moore RE,Slapak CA

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ABCC1 cDNA ORF clone, Canis lupus familiaris(dog)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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