Gene Symbol | mtcu-1 |
Entrez Gene ID | 3564835 |
Full Name | nuclear encoded Mitochondrial TRNA Carboxymethyl-amino-methyl modification of Uridine residues |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » mtcu-1 cDNA ORF clone
Gene Symbol | mtcu-1 |
Entrez Gene ID | 3564835 |
Full Name | nuclear encoded Mitochondrial TRNA Carboxymethyl-amino-methyl modification of Uridine residues |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_061172.5 | NP_493573.1 | TrmE-type G domain-containing protein |
NM_061172.4 | NP_493573.1 | nuclear encoded Mitochondrial TRNA Carboxymethyl-amino-methyl modification of Uridine residues |
Saccharomyces cerevisiae (baker's yeast) | MSS1 | NP_013736.1 |
Pan troglodytes (chimpanzee) | LOC748414 | XP_001161204.3 |
Canis lupus familiaris (dog) | GTPBP3 | XP_005632781.1 |
Mus musculus (house mouse) | Gtpbp3 | NP_115933.2 |
Rattus norvegicus (Norway rat) | Gtpbp3 | NP_001011919.1 |
Gallus gallus (chicken) | LOC100857447 | XP_003643536.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002133 | XP_320903.3 |
Schizosaccharomyces pombe (fission yeast) | mss1 | NP_593144.1 |
Bos taurus (cattle) | GTPBP3 | NP_001193147.1 |
Danio rerio (zebrafish) | gtpbp3 | NP_001018605.1 |
Drosophila melanogaster (fruit fly) | CG18528 | NP_651251.3 |
Kluyveromyces lactis | KLLA0E07657g | XP_454294.1 |
Eremothecium gossypii | AGOS_ABR063C | NP_983009.3 |
Magnaporthe oryzae (rice blast fungus) | MGG_04070 | XP_003719769.1 |
Xenopus tropicalis (tropical clawed frog) | gtpbp3 | XP_004911076.1 |
Homo sapiens (human) | GTPBP3 | NP_598399.2 |
Caenorhabditis elegans (roundworm) | F39B2.7 | NP_493573.1 |
Neurospora crassa | NCU04149 | XP_961305.1 |
Arabidopsis thaliana (thale cress) | AT1G78010 | NP_177924.3 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We further show that mtcu-1; mttu-1 and mtcu-2; mttu-1 double mutants display severe growth defects and sterility. The animal models presented here support the idea that the pathological states in humans may initially develop not as a direct consequence of a bioenergetic defect, but from the cell's maladaptive response to the hypomodification status of mt-tRNAs
Title: Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses.
The following mtcu-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mtcu-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335865 | |
Clone ID Related Accession (Same CDS sequence) | NM_061172.5 , NM_061172.4 | |
Accession Version | NM_061172.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | TrmE-type G domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_061172.4. |
1 | ATGTCGACAA TCTTCGCCCT ATCGTCTGGC ACATTGCCAA GCGCAATTGC GATGTTCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_493573.1 |
CDS | 12..1331 |
Translation |
Target ORF information:
Target ORF information:
|
NM_061172.5 |
1 | ATGTCGACAA TCTTCGCCCT ATCGTCTGGC ACATTGCCAA GCGCAATTGC GATGTTCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335865 | |
Clone ID Related Accession (Same CDS sequence) | NM_061172.5 , NM_061172.4 | |
Accession Version | NM_061172.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1320bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | nuclear encoded Mitochondrial TRNA Carboxymethyl-amino-methyl modification of Uridine residues | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_061172.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTCGACAA TCTTCGCCCT ATCGTCTGGC ACATTGCCAA GCGCAATTGC GATGTTCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_493573.1 |
CDS | 1..1320 |
Translation |
Target ORF information:
Target ORF information:
|
NM_061172.4 |
1 | ATGTCGACAA TCTTCGCCCT ATCGTCTGGC ACATTGCCAA GCGCAATTGC GATGTTCCGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |