Gene Symbol | rhgf-1 |
Entrez Gene ID | 184419 |
Full Name | RHo Guanine nucleotide exchange Factor |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » rhgf-1 cDNA ORF clone
Gene Symbol | rhgf-1 |
Entrez Gene ID | 184419 |
Full Name | RHo Guanine nucleotide exchange Factor |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_077390.9 | NP_509791.4 | RHo Guanine nucleotide exchange Factor |
NM_077390.7 | NP_509791.4 | RHo Guanine nucleotide exchange Factor |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Independent of myosin light chain activation, RHGF-1 acts via Rho-dependent kinase LET-502/ROCK and activates a conserved, retrograde DLK-1 MAPK pathway, triggering synaptic branch retraction and overgrowth of the PLM neurite in a dose-dependent manner.
Title: RHGF-1/PDZ-RhoGEF and retrograde DLK-1 signaling drive neuronal remodeling on microtubule disassembly.
we show that TIAM-1 acts with UNC-40/DCC in axon guidance, suggesting that TIAM-1 might regulate growth cone protrusion via Rac GTPases in response to UNC-40/DCC
Title: The Rac GTP exchange factor TIAM-1 acts with CDC-42 and the guidance receptor UNC-40/DCC in neuronal protrusion and axon guidance.
The upstream GPA-12/RHGF-1 pathway stimulates only a subset of RHO-1 downstream effectors, suggesting that either the RHO-1 effectors require different levels of activated RHO-1 or there are two distinct pools of RHO-1 within C. elegans neurons.
Title: The Galpha12-RGS RhoGEF-RhoA signalling pathway regulates neurotransmitter release in C. elegans.
The following rhgf-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the rhgf-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa348497 | |
Clone ID Related Accession (Same CDS sequence) | NM_077390.9 , NM_077390.7 | |
Accession Version | NM_077390.9 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4023bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | RHo Guanine nucleotide exchange Factor | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_077390.8. |
1 | ATGCGATCGT ACGAGTTTGT AACCAATACA CCACTCAAAC TTGATCGGCA CAAAGTATAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509791.4 |
CDS | 12..4034 |
Translation |
Target ORF information:
Target ORF information:
|
NM_077390.9 |
1 | ATGCGATCGT ACGAGTTTGT AACCAATACA CCACTCAAAC TTGATCGGCA CAAAGTATAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa348497 | |
Clone ID Related Accession (Same CDS sequence) | NM_077390.9 , NM_077390.7 | |
Accession Version | NM_077390.7 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4023bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | RHo Guanine nucleotide exchange Factor | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_077390.6. COMPLETENESS: incomplete on both ends. |
1 | ATGCGATCGT ACGAGTTTGT AACCAATACA CCACTCAAAC TTGATCGGCA CAAAGTATAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_509791.4 |
CDS | 1..4023 |
Translation |
Target ORF information:
Target ORF information:
|
NM_077390.7 |
1 | ATGCGATCGT ACGAGTTTGT AACCAATACA CCACTCAAAC TTGATCGGCA CAAAGTATAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |