dop-4 cDNA ORF clone, Caenorhabditis elegans

Gene
Clones
gRNAs

Summary

Gene Symbol	dop-4
Entrez Gene ID	183715
Full Name	Dopamine receptor 4
Gene Type	protein-coding
Organism	Caenorhabditis elegans

mRNA and Protein(s)

mRNA	Protein	Name
NM_075837.4	NP_508238.2	Dopamine receptor 4
NM_075837.2	NP_508238.2	Dopamine receptor 4

Pathways from BioSystems

Homologies

	ADRA1A	NP_001108205.1
Canis lupus familiaris (dog)	ADRA1A	NP_001182772.1
Mus musculus (house mouse)	Adra1a	NP_038489.2
Caenorhabditis elegans (roundworm)	dop-4	NP_508238.2
Rattus norvegicus (Norway rat)	Adra1a	NP_058887.2
Anopheles gambiae (African malaria mosquito)	GPROAR1	XP_311113.4
Xenopus tropicalis (tropical clawed frog)	LOC100492776	XP_002933012.2
Bos taurus (cattle)	ADRA1A	NP_776923.1
Gallus gallus (chicken)	ADRA1A	XP_425762.2
Homo sapiens (human)	ADRA1A	NP_000671.2
Pan troglodytes (chimpanzee)	ADRA1A	XP_003311731.1
Danio rerio (zebrafish)	LOC798498	XP_001338938.2
Drosophila melanogaster (fruit fly)	Oamb	NP_732542.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.

Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Study established a high-throughput learning assay that used real-time computer vision software for behavioral tracking and optogenetics for stimulation of the C. elegans polymodal nociceptor, ASH. Food and dopamine signaling slowed habituation downstream from ASH excitation via D1-like dopamine receptor, DOP-4. Assay allows for large-scale genetic and drug screens investigating mechanisms of nociception modulation.
Title: Dopamine receptor DOP-4 modulates habituation to repetitive photoactivation of a C. elegans polymodal nociceptor.

DOP-4 shows high sequence homology with D1-like dopamine receptors unique to invertebrates, distinct from mammalian D1-like dopamine receptors. Reporter gene assay showed that DOP-4 stimulates cAMP accumulation in response to dopamine stimulation.
Title: Characterization of a novel D2-like dopamine receptor with a truncated splice variant and a D1-like dopamine receptor unique to invertebrates from Caenorhabditis elegans.

The following dop-4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dop-4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCa349462	NM_075837.4 Latest version!	Caenorhabditis elegans Dopamine receptor 4 (dop-4), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$307.30 $439.00
View Old Accession Versions >>
OCa349462	NM_075837.2	Caenorhabditis elegans Dopamine receptor 4 (dop-4), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$342.30 $489.00
Hide Old Accession Versions >>

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

dop-4 ( NM_075837.4 ) cDNA ORF clone, Caenorhabditis elegans -> NP_508238.2 Caenorhabditis elegans Dopamine receptor 4 (dop-4), mRNA.

Price & Availability↑

CloneID	OCa349462
Clone ID Related Accession (Same CDS sequence)	NM_075837.4 , NM_075837.2
Accession Version	NM_075837.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Caenorhabditis elegans
Product	Dopamine receptor 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_075837.3.

ATGTTGGCTT ACGGGTCTGA TCCGAACGCC GAAGACCTCT ATATCACAAT GACACCGTCC 
GTCTCAACAG AAAACGACAC CACAGTCTGG GCGACAGAGG AGCCGGCGGC AATTGTGTGG 
AGACATCCCC TATTGGCAAT TGCATTGTTT TCCATTTGTC TGCTCACAGT TGCTGGAAAT 
TGTCTGGTTG TGATTGCAGT GTGTACTAAG AAGTATTTAA GGAATCCCAC TGGGTACCTA 
ATTATCTCAT TGGCAATAGC AGATCTCATA GTAGGCGTGA TAGTGATGCC TATGAATTCA 
TTATTTGAAA TTGCAAATCA CACGTGGCTT TTTGGCCTGA TGATGTGTGA TGTGTTCCAC 
GCGATGGACA TTCTTGCGTC GACAGCTTCG ATATGGAACC TATGCGTCAT TAGTCTAGAC 
AGATACATGG CCGGTCAGGA CCCAATTGGC TATAGAGATA AAGTCTCGAA AAGGAGGATC 
TTAATGGCTA TTCTGAGTGT ATGGGTGTTG TCTGCAATTC TATCGTTTCC TGGAATTATT 
TGGTGGCGGA CTAGTTCTCC GCATTTGTAT GAAGATCAGT CACAATGTCT ATTCACGGAC 
AGCAAAATGT ATGTGAGCTT CTCTTCATTA GTTTCGTTCT ACATCCCGCT CTTCCTCATT 
CTCTTCGCAT ATGGAAAGGT CTACATAATT GCGACGCGAC ATTCAAAAGG CATGCGGATG 
GGTATCAAAA CAGTCAGCAT CAAAAAACGG AATGGAAAAA AATCCAACAC GGAGACAGAG 
AGCATCTTGT CCAGTGAGAA TGAGCCAACA TTGCGGATTC ATTTCGGGCG GGGGAAGCAG 
TCGAGTTCCA GCTTAAGAAA TAGCAGGTTT CATGCCAGAG AGTCCACGAG GTTGCTTTTA 
AAGCAGGTAT CCTGTAAATC ATTAAACGAT CGTGGCGAGC ACAACAATAA TAACACGGTG 
CGGCAGCCAT TGCTCCGTGG CACAGAAGGT TGCCATTCCG ACTCCATTAG TCGTTCCTCG 
CAACGTAACT TTCGTGGCAG GAATGTTACG ATCGGGAGTA ACTGCTCTTC GACTCTTCTG 
CAAGTTGATC AGCCGGATCG TATGTCGCTC TCCTCCAACT CCCAAATGGT GATGACATCT 
CCCTTATCAA CGCGTCGAAA ATTGAATGTT CGAGAAAAAT CGCGCCAAAT GATGCGCTAC 
GTCCACGAGC AACGTGCAGC TCGGACACTT TCCATTGTGG TCGGAGCATT TATTCTCTGC 
TGGACACCAT TTTTCGTGTT CACTCCGCTC ACCGCGTTCT GTGAAAGTTG TTTCTCCAAC 
AAAGAGACCA TCTTCACATT CGTCACATGG GCCGGTCACC TAAACTCAAT GCTCAACCCG 
CTCATCTACT CGCGCTTCTC GCGAGATTTC AGACGGGCAT TCAAGCAAAT TCTCACGTGT 
CAACGCCAGC AAAAGGTGAA AACCGCATTT AAAACGCCAC TGTCACTCGT GTTCACTCAA 
CTCATCTCGG TCACCCAAAT GTGGGAGCAA CCGCCGAATA CTTCAATTGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_508238.2
CDS	25..1578
Translation	MLAYGSDPNAEDLYITMTPSVSTENDTTVWATEEPAAIVWRHPLLAIALFSICLLTVAGNCLVVIAVCTKKYLRNPTGYLIISLAIADLIVGVIVMPMNSLFEIANHTWLFGLMMCDVFHAMDILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVWVLSAILSFPGIIWWRTSSPHLYEDQSQCLFTDSKMYVSFSSLVSFYIPLFLILFAYGKVYIIATRHSKGMRMGIKTVSIKKRNGKKSNTETESILSSENEPTLRIHFGRGKQSSSSLRNSRFHARESTRLLLKQVSCKSLNDRGEHNNNNTVRQPLLRGTEGCHSDSISRSSQRNFRGRNVTIGSNCSSTLLQVDQPDRMSLSSNSQMVMTSPLSTRRKLNVREKSRQMMRYVHEQRAARTLSIVVGAFILCWTPFFVFTPLTAFCESCFSNKETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQILTCQRQQKVKTAFKTPLSLVFTQLISVTQMWEQPPNTSIE

Target ORF information:

RefSeq Version	NM_075837.4
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Dopamine receptor 4 (dop-4), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_075837.4

ORF Insert Sequence:

ATGTTGGCTT ACGGGTCTGA TCCGAACGCC GAAGACCTCT ATATCACAAT GACACCGTCC 
GTCTCAACAG AAAACGACAC CACAGTCTGG GCGACAGAGG AGCCGGCGGC AATTGTGTGG 
AGACATCCCC TATTGGCAAT TGCATTGTTT TCCATTTGTC TGCTCACAGT TGCTGGAAAT 
TGTCTGGTTG TGATTGCAGT GTGTACTAAG AAGTATTTAA GGAATCCCAC TGGGTACCTA 
ATTATCTCAT TGGCAATAGC AGATCTCATA GTAGGCGTGA TAGTGATGCC TATGAATTCA 
TTATTTGAAA TTGCAAATCA CACGTGGCTT TTTGGCCTGA TGATGTGTGA TGTGTTCCAC 
GCGATGGACA TTCTTGCGTC GACAGCTTCG ATATGGAACC TATGCGTCAT TAGTCTAGAC 
AGATACATGG CCGGTCAGGA CCCAATTGGC TATAGAGATA AAGTCTCGAA AAGGAGGATC 
TTAATGGCTA TTCTGAGTGT ATGGGTGTTG TCTGCAATTC TATCGTTTCC TGGAATTATT 
TGGTGGCGGA CTAGTTCTCC GCATTTGTAT GAAGATCAGT CACAATGTCT ATTCACGGAC 
AGCAAAATGT ATGTGAGCTT CTCTTCATTA GTTTCGTTCT ACATCCCGCT CTTCCTCATT 
CTCTTCGCAT ATGGAAAGGT CTACATAATT GCGACGCGAC ATTCAAAAGG CATGCGGATG 
GGTATCAAAA CAGTCAGCAT CAAAAAACGG AATGGAAAAA AATCCAACAC GGAGACAGAG 
AGCATCTTGT CCAGTGAGAA TGAGCCAACA TTGCGGATTC ATTTCGGGCG GGGGAAGCAG 
TCGAGTTCCA GCTTAAGAAA TAGCAGGTTT CATGCCAGAG AGTCCACGAG GTTGCTTTTA 
AAGCAGGTAT CCTGTAAATC ATTAAACGAT CGTGGCGAGC ACAACAATAA TAACACGGTG 
CGGCAGCCAT TGCTCCGTGG CACAGAAGGT TGCCATTCCG ACTCCATTAG TCGTTCCTCG 
CAACGTAACT TTCGTGGCAG GAATGTTACG ATCGGGAGTA ACTGCTCTTC GACTCTTCTG 
CAAGTTGATC AGCCGGATCG TATGTCGCTC TCCTCCAACT CCCAAATGGT GATGACATCT 
CCCTTATCAA CGCGTCGAAA ATTGAATGTT CGAGAAAAAT CGCGCCAAAT GATGCGCTAC 
GTCCACGAGC AACGTGCAGC TCGGACACTT TCCATTGTGG TCGGAGCATT TATTCTCTGC 
TGGACACCAT TTTTCGTGTT CACTCCGCTC ACCGCGTTCT GTGAAAGTTG TTTCTCCAAC 
AAAGAGACCA TCTTCACATT CGTCACATGG GCCGGTCACC TAAACTCAAT GCTCAACCCG 
CTCATCTACT CGCGCTTCTC GCGAGATTTC AGACGGGCAT TCAAGCAAAT TCTCACGTGT 
CAACGCCAGC AAAAGGTGAA AACCGCATTT AAAACGCCAC TGTCACTCGT GTTCACTCAA 
CTCATCTCGG TCACCCAAAT GTGGGAGCAA CCGCCGAATA CTTCAATTGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

dop-4 ( NM_075837.2 ) cDNA ORF clone, Caenorhabditis elegans -> NP_508238.2 Caenorhabditis elegans Dopamine receptor 4 (dop-4), partial mRNA.

Price & Availability↑

CloneID	OCa349462
Clone ID Related Accession (Same CDS sequence)	NM_075837.4 , NM_075837.2
Accession Version	NM_075837.2	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1554bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Caenorhabditis elegans
Product	Dopamine receptor 4
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Feb 6, 2006 this sequence version replaced NM_075837.1. COMPLETENESS: incomplete on both ends.

ATGTTGGCTT ACGGGTCTGA TCCGAACGCC GAAGACCTCT ATATCACAAT GACACCGTCC 
GTCTCAACAG AAAACGACAC CACAGTCTGG GCGACAGAGG AGCCGGCGGC AATTGTGTGG 
AGACATCCCC TATTGGCAAT TGCATTGTTT TCCATTTGTC TGCTCACAGT TGCTGGAAAT 
TGTCTGGTTG TGATTGCAGT GTGTACTAAG AAGTATTTAA GGAATCCCAC TGGGTACCTA 
ATTATCTCAT TGGCAATAGC AGATCTCATA GTAGGCGTGA TAGTGATGCC TATGAATTCA 
TTATTTGAAA TTGCAAATCA CACGTGGCTT TTTGGCCTGA TGATGTGTGA TGTGTTCCAC 
GCGATGGACA TTCTTGCGTC GACAGCTTCG ATATGGAACC TATGCGTCAT TAGTCTAGAC 
AGATACATGG CCGGTCAGGA CCCAATTGGC TATAGAGATA AAGTCTCGAA AAGGAGGATC 
TTAATGGCTA TTCTGAGTGT ATGGGTGTTG TCTGCAATTC TATCGTTTCC TGGAATTATT 
TGGTGGCGGA CTAGTTCTCC GCATTTGTAT GAAGATCAGT CACAATGTCT ATTCACGGAC 
AGCAAAATGT ATGTGAGCTT CTCTTCATTA GTTTCGTTCT ACATCCCGCT CTTCCTCATT 
CTCTTCGCAT ATGGAAAGGT CTACATAATT GCGACGCGAC ATTCAAAAGG CATGCGGATG 
GGTATCAAAA CAGTCAGCAT CAAAAAACGG AATGGAAAAA AATCCAACAC GGAGACAGAG 
AGCATCTTGT CCAGTGAGAA TGAGCCAACA TTGCGGATTC ATTTCGGGCG GGGGAAGCAG 
TCGAGTTCCA GCTTAAGAAA TAGCAGGTTT CATGCCAGAG AGTCCACGAG GTTGCTTTTA 
AAGCAGGTAT CCTGTAAATC ATTAAACGAT CGTGGCGAGC ACAACAATAA TAACACGGTG 
CGGCAGCCAT TGCTCCGTGG CACAGAAGGT TGCCATTCCG ACTCCATTAG TCGTTCCTCG 
CAACGTAACT TTCGTGGCAG GAATGTTACG ATCGGGAGTA ACTGCTCTTC GACTCTTCTG 
CAAGTTGATC AGCCGGATCG TATGTCGCTC TCCTCCAACT CCCAAATGGT GATGACATCT 
CCCTTATCAA CGCGTCGAAA ATTGAATGTT CGAGAAAAAT CGCGCCAAAT GATGCGCTAC 
GTCCACGAGC AACGTGCAGC TCGGACACTT TCCATTGTGG TCGGAGCATT TATTCTCTGC 
TGGACACCAT TTTTCGTGTT CACTCCGCTC ACCGCGTTCT GTGAAAGTTG TTTCTCCAAC 
AAAGAGACCA TCTTCACATT CGTCACATGG GCCGGTCACC TAAACTCAAT GCTCAACCCG 
CTCATCTACT CGCGCTTCTC GCGAGATTTC AGACGGGCAT TCAAGCAAAT TCTCACGTGT 
CAACGCCAGC AAAAGGTGAA AACCGCATTT AAAACGCCAC TGTCACTCGT GTTCACTCAA 
CTCATCTCGG TCACCCAAAT GTGGGAGCAA CCGCCGAATA CTTCAATTGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_508238.2
CDS	1..1554
Translation	MLAYGSDPNAEDLYITMTPSVSTENDTTVWATEEPAAIVWRHPLLAIALFSICLLTVAGNCLVVIAVCTKKYLRNPTGYLIISLAIADLIVGVIVMPMNSLFEIANHTWLFGLMMCDVFHAMDILASTASIWNLCVISLDRYMAGQDPIGYRDKVSKRRILMAILSVWVLSAILSFPGIIWWRTSSPHLYEDQSQCLFTDSKMYVSFSSLVSFYIPLFLILFAYGKVYIIATRHSKGMRMGIKTVSIKKRNGKKSNTETESILSSENEPTLRIHFGRGKQSSSSLRNSRFHARESTRLLLKQVSCKSLNDRGEHNNNNTVRQPLLRGTEGCHSDSISRSSQRNFRGRNVTIGSNCSSTLLQVDQPDRMSLSSNSQMVMTSPLSTRRKLNVREKSRQMMRYVHEQRAARTLSIVVGAFILCWTPFFVFTPLTAFCESCFSNKETIFTFVTWAGHLNSMLNPLIYSRFSRDFRRAFKQILTCQRQQKVKTAFKTPLSLVFTQLISVTQMWEQPPNTSIE

Target ORF information:

RefSeq Version	NM_075837.2
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Dopamine receptor 4 (dop-4), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_075837.2

ORF Insert Sequence:

ATGTTGGCTT ACGGGTCTGA TCCGAACGCC GAAGACCTCT ATATCACAAT GACACCGTCC 
GTCTCAACAG AAAACGACAC CACAGTCTGG GCGACAGAGG AGCCGGCGGC AATTGTGTGG 
AGACATCCCC TATTGGCAAT TGCATTGTTT TCCATTTGTC TGCTCACAGT TGCTGGAAAT 
TGTCTGGTTG TGATTGCAGT GTGTACTAAG AAGTATTTAA GGAATCCCAC TGGGTACCTA 
ATTATCTCAT TGGCAATAGC AGATCTCATA GTAGGCGTGA TAGTGATGCC TATGAATTCA 
TTATTTGAAA TTGCAAATCA CACGTGGCTT TTTGGCCTGA TGATGTGTGA TGTGTTCCAC 
GCGATGGACA TTCTTGCGTC GACAGCTTCG ATATGGAACC TATGCGTCAT TAGTCTAGAC 
AGATACATGG CCGGTCAGGA CCCAATTGGC TATAGAGATA AAGTCTCGAA AAGGAGGATC 
TTAATGGCTA TTCTGAGTGT ATGGGTGTTG TCTGCAATTC TATCGTTTCC TGGAATTATT 
TGGTGGCGGA CTAGTTCTCC GCATTTGTAT GAAGATCAGT CACAATGTCT ATTCACGGAC 
AGCAAAATGT ATGTGAGCTT CTCTTCATTA GTTTCGTTCT ACATCCCGCT CTTCCTCATT 
CTCTTCGCAT ATGGAAAGGT CTACATAATT GCGACGCGAC ATTCAAAAGG CATGCGGATG 
GGTATCAAAA CAGTCAGCAT CAAAAAACGG AATGGAAAAA AATCCAACAC GGAGACAGAG 
AGCATCTTGT CCAGTGAGAA TGAGCCAACA TTGCGGATTC ATTTCGGGCG GGGGAAGCAG 
TCGAGTTCCA GCTTAAGAAA TAGCAGGTTT CATGCCAGAG AGTCCACGAG GTTGCTTTTA 
AAGCAGGTAT CCTGTAAATC ATTAAACGAT CGTGGCGAGC ACAACAATAA TAACACGGTG 
CGGCAGCCAT TGCTCCGTGG CACAGAAGGT TGCCATTCCG ACTCCATTAG TCGTTCCTCG 
CAACGTAACT TTCGTGGCAG GAATGTTACG ATCGGGAGTA ACTGCTCTTC GACTCTTCTG 
CAAGTTGATC AGCCGGATCG TATGTCGCTC TCCTCCAACT CCCAAATGGT GATGACATCT 
CCCTTATCAA CGCGTCGAAA ATTGAATGTT CGAGAAAAAT CGCGCCAAAT GATGCGCTAC 
GTCCACGAGC AACGTGCAGC TCGGACACTT TCCATTGTGG TCGGAGCATT TATTCTCTGC 
TGGACACCAT TTTTCGTGTT CACTCCGCTC ACCGCGTTCT GTGAAAGTTG TTTCTCCAAC 
AAAGAGACCA TCTTCACATT CGTCACATGG GCCGGTCACC TAAACTCAAT GCTCAACCCG 
CTCATCTACT CGCGCTTCTC GCGAGATTTC AGACGGGCAT TCAAGCAAAT TCTCACGTGT 
CAACGCCAGC AAAAGGTGAA AACCGCATTT AAAACGCCAC TGTCACTCGT GTTCACTCAA 
CTCATCTCGG TCACCCAAAT GTGGGAGCAA CCGCCGAATA CTTCAATTGA ATAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

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dop-4 cDNA ORF clone, Caenorhabditis elegans

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

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