Gene Symbol | alg-1 |
Entrez Gene ID | 181504 |
Full Name | Protein argonaute |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » alg-1 cDNA ORF clone
Gene Symbol | alg-1 |
Entrez Gene ID | 181504 |
Full Name | Protein argonaute |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001270310.1 | NP_001257239.1 | Protein argonaute |
NM_001270309.1 | NP_001257238.1 | Protein argonaute |
NM_001270310.3 | NP_001257239.1 | Protein argonaute |
NM_001270309.2 | NP_001257238.1 | Protein argonaute |
Xenopus tropicalis (tropical clawed frog) | ago2 | NP_001004877.1 |
Pan troglodytes (chimpanzee) | EIF2C2 | XP_001142838.1 |
Rattus norvegicus (Norway rat) | Ago2 | NP_067608.1 |
Drosophila melanogaster (fruit fly) | AGO1 | NP_001246314.1 |
Homo sapiens (human) | AGO2 | NP_036286.2 |
Canis lupus familiaris (dog) | AGO2 | XP_005628049.1 |
Bos taurus (cattle) | EIF2C2 | NP_991363.1 |
Danio rerio (zebrafish) | LOC570630 | XP_699226.2 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011717 | XP_320795.4 |
Mus musculus (house mouse) | Ago2 | NP_694818.3 |
Caenorhabditis elegans (roundworm) | alg-1 | NP_001257238.1 |
Arabidopsis thaliana (thale cress) | AGO5 | NP_850110.1 |
LOC711873 | XP_001100725.2 | |
Gallus gallus (chicken) | LOC100858102 | XP_004940122.1 |
Caenorhabditis elegans (roundworm) | alg-2 | NP_871992.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Altogether, these data suggest that the phosphorylation state of the serine/threonine cluster is important for Argonaute-mRNA interactions.
Title: Phosphorylation of Argonaute proteins affects mRNA binding and is essential for microRNA-guided gene silencing
knockdown of alg-1 and alg-2 in germ cells results in few defects in oocyte maturation and ovulation.
Title: Functional analysis of microRNA pathway genes in the somatic gonad and germ cells during ovulation in C. elegans.
We show in vitro and in vivo that their mutations severely altered the association with AIN-1 and AIN-2. our results demonstrate that the microRNA pathway can act independently of GW182 proteins during C. elegans embryogenesis
Title: GW182-Free microRNA Silencing Complex Controls Post-transcriptional Gene Expression during Caenorhabditis elegans Embryogenesis.
Pairing beyond the seed supports ALG-1 microRNA targeting specificity.
Title: Pairing beyond the Seed Supports MicroRNA Targeting Specificity.
ALG-1 complexes recognize structural features of particular microRNAs in the context of conducting the strand selection and microRNA* ejection steps of miRISC maturation
Title: Caenorhabditis elegans ALG-1 antimorphic mutations uncover functions for Argonaute in microRNA guide strand selection and passenger strand disposal.
The following alg-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the alg-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa348651 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270309.1 , NM_001270309.2 | |
Accession Version | NM_001270309.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3009bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein argonaute | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). COMPLETENESS: incomplete on both ends. |
1 | ATGTCCGGCG GGCCGCAATA TTTGCCAGGA GTCATGAATT CTACCATTCA ACAGCAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001257238.1 |
CDS | 1..3009 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001270309.1 |
1 | ATGTCCGGCG GGCCGCAATA TTTGCCAGGA GTCATGAATT CTACCATTCA ACAGCAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa348651 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270309.1 , NM_001270309.2 | |
Accession Version | NM_001270309.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3009bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein argonaute | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Sep 4, 2019 this sequence version replaced NM_001270309.1. |
1 | ATGTCCGGCG GGCCGCAATA TTTGCCAGGA GTCATGAATT CTACCATTCA ACAGCAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001257238.1 |
CDS | 30..3038 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001270309.2 |
1 | ATGTCCGGCG GGCCGCAATA TTTGCCAGGA GTCATGAATT CTACCATTCA ACAGCAACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa350265 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270310.1 , NM_001270310.3 | |
Accession Version | NM_001270310.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3072bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein argonaute | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). COMPLETENESS: incomplete on both ends. |
1 | ATGGCTGCCG AACTGAACAA CACCAACACA AATGAGTCGT CTAACGTCGC CTCAAACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001257239.1 |
CDS | 1..3072 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001270310.1 |
1 | ATGGCTGCCG AACTGAACAA CACCAACACA AATGAGTCGT CTAACGTCGC CTCAAACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa350265 | |
Clone ID Related Accession (Same CDS sequence) | NM_001270310.1 , NM_001270310.3 | |
Accession Version | NM_001270310.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3072bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein argonaute | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_001270310.2. |
1 | ATGGCTGCCG AACTGAACAA CACCAACACA AATGAGTCGT CTAACGTCGC CTCAAACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001257239.1 |
CDS | 380..3451 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001270310.3 |
1 | ATGGCTGCCG AACTGAACAA CACCAACACA AATGAGTCGT CTAACGTCGC CTCAAACGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |