| Gene Symbol | npr-1 |
| Entrez Gene ID | 180752 |
| Full Name | NeuroPeptide Receptor family |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » npr-1 cDNA ORF clone
| Gene Symbol | npr-1 |
| Entrez Gene ID | 180752 |
| Full Name | NeuroPeptide Receptor family |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_076415.6 | NP_508816.1 | G_PROTEIN_RECEP_F1_2 domain-containing protein |
| NM_076415.4 | NP_508816.1 | NeuroPeptide Receptor family |
| Homo sapiens (human) | HCRTR2 | NP_001517.2 |
| HCRTR2 | XP_001109616.1 | |
| Xenopus tropicalis (tropical clawed frog) | hcrtr2 | XP_002934896.2 |
| Caenorhabditis elegans (roundworm) | npr-2 | NP_501701.2 |
| Pan troglodytes (chimpanzee) | HCRTR2 | XP_518552.2 |
| Bos taurus (cattle) | HCRTR2 | NP_001179606.1 |
| Mus musculus (house mouse) | Hcrtr2 | NP_945200.1 |
| Gallus gallus (chicken) | HCRTR2 | NP_001019755.1 |
| Canis lupus familiaris (dog) | HCRTR2 | NP_001002933.1 |
| Rattus norvegicus (Norway rat) | Hcrtr2 | NP_037206.1 |
| Danio rerio (zebrafish) | hcrtr2 | NP_001073337.1 |
| Caenorhabditis elegans (roundworm) | npr-1 | NP_508816.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
npr-1 allows the invertebrate immune system to produce highly specialized and potentially opposing immune responses
Title: Contrasting invertebrate immune defense behaviors caused by a single gene, the Caenorhabditis elegans neuropeptide receptor gene npr-1.
The effects of food on adaptation are affected by neuropeptide signaling; the neuropeptide receptors NPR-1 and NPR-2 act to increase adaptation off food.
Title: Neuropeptidergic Signaling and Active Feeding State Inhibit Nociception in Caenorhabditis elegans.
OCR-2 and NPR-1 likely act via a calcium-dependent but MEF-2- and DAF-16-independent pathway...sensory- and circuit-mediated regulation of chemoreceptor genes via multiple pathways .
Title: Feeding state, insulin and NPR-1 modulate chemoreceptor gene expression via integration of sensory and circuit inputs.
These results suggest that variation in npr-1 has broad pleiotropic effects mediated by altered exposure to bacterial food.
Title: A variant in the neuropeptide receptor npr-1 is a major determinant of Caenorhabditis elegans growth and physiology.
This study demonistrated that NPR-1 regulate the circuit mechanism for behavioral quiescence in C. elegans.
Title: Analysis of NPR-1 reveals a circuit mechanism for behavioral quiescence in C. elegans.
The following npr-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the npr-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa349529 | |
| Clone ID Related Accession (Same CDS sequence) | NM_076415.6 , NM_076415.4 | |
| Accession Version | NM_076415.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | G_PROTEIN_RECEP_F1_2 domain-containing protein | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Oct 18, 2019 this sequence version replaced NM_076415.5. | |
1 | ATGGAAGTTG AAAATTTTAC CGACTGTCAA GTATATTGGA AAGTGTATCC AGATCCTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_508816.1 |
| CDS | 12..1385 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_076415.6 |
1 | ATGGAAGTTG AAAATTTTAC CGACTGTCAA GTATATTGGA AAGTGTATCC AGATCCTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa349529 | |
| Clone ID Related Accession (Same CDS sequence) | NM_076415.6 , NM_076415.4 | |
| Accession Version | NM_076415.4 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1374bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | NeuroPeptide Receptor family | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003284). On Jun 26, 2012 this sequence version replaced NM_076415.3. COMPLETENESS: incomplete on both ends. | |
1 | ATGGAAGTTG AAAATTTTAC CGACTGTCAA GTATATTGGA AAGTGTATCC AGATCCTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_508816.1 |
| CDS | 1..1374 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_076415.4 |
1 | ATGGAAGTTG AAAATTTTAC CGACTGTCAA GTATATTGGA AAGTGTATCC AGATCCTTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |