Gene Symbol | sfa-1 |
Entrez Gene ID | 178486 |
Full Name | Splicing FActor |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » sfa-1 cDNA ORF clone
Gene Symbol | sfa-1 |
Entrez Gene ID | 178486 |
Full Name | Splicing FActor |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_070632.5 | NP_503033.1 | Splicing FActor |
NM_070632.6 | NP_503033.1 | CCHC-type domain-containing protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
SFA-1 is specifically required for lifespan extension by dietary restriction and by modulation of the TORC1 pathway components AMPK, RAGA-1 and RSKS-1/S6 kinase; we also demonstrate that overexpression of SFA-1 is sufficient to extend lifespan; together, these data demonstrate a role for RNA splicing homeostasis in dietary restriction longevity
Title: Splicing factor 1 modulates dietary restriction and TORC1 pathway longevity in C. elegans.
in vivo evidence that SFA-1 regulates alternative splicing.
Title: In vivo effects on intron retention and exon skipping by the U2AF large subunit and SF1/BBP in the nematode Caenorhabditis elegans.
The following sfa-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the sfa-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa342503 | |
Clone ID Related Accession (Same CDS sequence) | NM_070632.5 , NM_070632.6 | |
Accession Version | NM_070632.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2100bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | CCHC-type domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_070632.5. COMPLETENESS: incomplete on the 5' end. |
1 | ATGTCGAAAA CTGGTGGAAA CACGGAGCCA ATGCCATTCA TCCGGAAATG GGGCAACGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_503033.1 |
CDS | 1..2100 |
Translation |
Target ORF information:
Target ORF information:
|
NM_070632.6 |
1 | ATGTCGAAAA CTGGTGGAAA CACGGAGCCA ATGCCATTCA TCCGGAAATG GGGCAACGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342503 | |
Clone ID Related Accession (Same CDS sequence) | NM_070632.5 , NM_070632.6 | |
Accession Version | NM_070632.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2100bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Splicing FActor | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_070632.4. COMPLETENESS: incomplete on both ends. |
1 | ATGTCGAAAA CTGGTGGAAA CACGGAGCCA ATGCCATTCA TCCGGAAATG GGGCAACGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_503033.1 |
CDS | 1..2100 |
Translation |
Target ORF information:
Target ORF information:
|
NM_070632.5 |
1 | ATGTCGAAAA CTGGTGGAAA CACGGAGCCA ATGCCATTCA TCCGGAAATG GGGCAACGAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |