Gene Symbol | rho-1 |
Entrez Gene ID | 178458 |
Full Name | Ras-like GTP-binding protein rhoA |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » rho-1 cDNA ORF clone
Gene Symbol | rho-1 |
Entrez Gene ID | 178458 |
Full Name | Ras-like GTP-binding protein rhoA |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_070558.6 | NP_502959.1 | Ras-like GTP-binding protein rhoA |
NM_070558.7 | NP_502959.1 | Ras-like GTP-binding protein rhoA |
Canis lupus familiaris (dog) | RHOC | XP_540336.2 |
Danio rerio (zebrafish) | rhoad | NP_001002445.1 |
Danio rerio (zebrafish) | rhoac | NP_998515.1 |
Danio rerio (zebrafish) | rhoae | NP_957444.1 |
Bos taurus (cattle) | RHOC | NP_001039603.1 |
Xenopus tropicalis (tropical clawed frog) | rhoc | NP_001016569.1 |
Homo sapiens (human) | RHOC | NP_001036143.1 |
Pan troglodytes (chimpanzee) | RHOC | XP_003339043.1 |
Mus musculus (house mouse) | Rhoc | NP_031510.2 |
Rattus norvegicus (Norway rat) | Rhoc | NP_001099931.1 |
Gallus gallus (chicken) | RHOC | NP_001025020.1 |
Danio rerio (zebrafish) | rhoaa | NP_998302.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005160 | XP_001688510.1 |
Caenorhabditis elegans (roundworm) | rho-1 | NP_502959.1 |
Eremothecium gossypii | AGOS_ABR182W | NP_983130.1 |
Drosophila melanogaster (fruit fly) | Rho1 | NP_995851.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our results suggest that NCA-1 and NCA-2 are physiologically relevant targets of neuronal Gq-Rho signaling in C. elegans
Title: The NCA-1 and NCA-2 Ion Channels Function Downstream of G
Here, the authors report that in the Caenorhabditis elegans zygote, feedback between active RhoA and myosin induces a contractile instability in the actomyosin cell cortex.
Title: Controlling contractile instabilities in the actomyosin cortex.
Thus, counterintuitively, CYK-4 RhoGAP activity promotes RhoA activation.
Title: The RhoGAP activity of CYK-4/MgcRacGAP functions non-canonically by promoting RhoA activation during cytokinesis.
Actomyosin contractility in the C. elegans spermatheca is under control of RHO-1/RhoA, which, in turn, is regulated by the F-BAR and RhoGAP protein SPV-1. In the relaxed spermatheca, SPV-1 localizes through its F-BAR domain to the apical membrane.
Title: Transient membrane localization of SPV-1 drives cyclical actomyosin contractions in the C. elegans spermatheca.
These observations indicate neuronally expressed RHGF-2 is an essential RHO-1 specific RhoGEF that binds most strongly to MPZ-1 PDZ domain eight and is required for wild-type C. elegans morphology and growth.
Title: RHGF-2 is an essential Rho-1 specific RhoGEF that binds to the multi-PDZ domain scaffold protein MPZ-1 in Caenorhabditis elegans.
The following rho-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the rho-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa343426 | |
Clone ID Related Accession (Same CDS sequence) | NM_070558.6 , NM_070558.7 | |
Accession Version | NM_070558.6 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Ras-like GTP-binding protein rhoA | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_070558.5. COMPLETENESS: incomplete on both ends. |
1 | ATGGCTGCGA TTAGAAAGAA GTTGGTGATC GTCGGCGACG GAGCCTGCGG TAAAACTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_502959.1 |
CDS | 1..579 |
Translation |
Target ORF information:
Target ORF information:
|
NM_070558.6 |
1 | ATGGCTGCGA TTAGAAAGAA GTTGGTGATC GTCGGCGACG GAGCCTGCGG TAAAACTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343426 | |
Clone ID Related Accession (Same CDS sequence) | NM_070558.6 , NM_070558.7 | |
Accession Version | NM_070558.7 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 579bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Ras-like GTP-binding protein rhoA | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_070558.6. |
1 | ATGGCTGCGA TTAGAAAGAA GTTGGTGATC GTCGGCGACG GAGCCTGCGG TAAAACTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_502959.1 |
CDS | 56..634 |
Translation |
Target ORF information:
Target ORF information:
|
NM_070558.7 |
1 | ATGGCTGCGA TTAGAAAGAA GTTGGTGATC GTCGGCGACG GAGCCTGCGG TAAAACTTGC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |