arl-8 cDNA ORF clone, Caenorhabditis elegans

Gene
Clones
gRNAs

Summary

Gene Symbol	arl-8
Entrez Gene ID	178405
Full Name	ARF-Like
Gene Type	protein-coding
Organism	Caenorhabditis elegans

mRNA and Protein(s)

mRNA	Protein	Name
NM_070390.7	NP_502791.1	ARF-Like
NM_070390.6	NP_502791.1	ARF-Like

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	ARL8A	XP_524523.3
	LOC706361	XP_001106667.2
Bos taurus (cattle)	ARL8A	XP_005217479.1
Arabidopsis thaliana (thale cress)	ARLA1D	NP_569051.1
Oryza sativa (rice)	Os03g0200800	NP_001049292.1
Mus musculus (house mouse)	Arl8a	NP_081099.1
Caenorhabditis elegans (roundworm)	arl-8	NP_502791.1
Arabidopsis thaliana (thale cress)	ARLA1C	NP_190556.2
Homo sapiens (human)	ARL8A	NP_620150.1
Rattus norvegicus (Norway rat)	Arl8a	NP_001102541.1
Magnaporthe oryzae (rice blast fungus)	MGG_01574	XP_003714552.1
Neurospora crassa	NCU08618	XP_964826.1
Xenopus tropicalis (tropical clawed frog)	arl8a	NP_988990.1
Gallus gallus (chicken)	ARL8A	NP_001012886.1
Danio rerio (zebrafish)	arl8a	NP_001186949.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.

Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Synaptic vesicle bound small GTPase ARL-8 activates UNC-104 by unlocking the autoinhibition. The results demonstrate that the autoinhibitory mechanism is utilized to regulate the distribution of transport cargoes and is important for synaptogenesis in vivo.
Title: Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses.

ARL-8 inhibits presynaptic assembly by promoting dissociation.
Title: The balance between capture and dissociation of presynaptic proteins controls the spatial distribution of synapses.

ARL-8 facilitates apoptotic cell removal in vivo by mediating phagosome-lysosome fusion during phagocytosis.
Title: Arl8/ARL-8 functions in apoptotic cell removal by mediating phagolysosome formation in Caenorhabditis elegans.

ARL-8 mediates delivery of endocytosed macromolecules to lysosomes by facilitating late endosome-lysosome fusion.
Title: The arf-like GTPase Arl8 mediates delivery of endocytosed macromolecules to lysosomes in Caenorhabditis elegans.

ARL-8 is required during presynaptic assembly of requisite proteins into vesicular cargoes in the cell soma, their long-distance microtubule-dependent transport down the axon, and their reconstitution into functional complexes at prespecified sites.
Title: An Arf-like small G protein, ARL-8, promotes the axonal transport of presynaptic cargoes by suppressing vesicle aggregation.

The following arl-8 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the arl-8 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCa342750	NM_070390.7 Latest version!	Caenorhabditis elegans ARF-Like (arl-8), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$69.30 $99.00
View Old Accession Versions >>
OCa342750	NM_070390.6	Caenorhabditis elegans ARF-Like (arl-8), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$104.30 $149.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

arl-8 ( NM_070390.7 ) cDNA ORF clone, Caenorhabditis elegans -> NP_502791.1 Caenorhabditis elegans ARF-Like (arl-8), mRNA.

Price & Availability↑

CloneID	OCa342750
Clone ID Related Accession (Same CDS sequence)	NM_070390.7 , NM_070390.6
Accession Version	NM_070390.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Caenorhabditis elegans
Product	ARF-Like
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_070390.6.

ATGTTGGCTA TGGTGAATAA GGTTCTCGAC TGGATTCGCA GTCTTTTTTG GAAAGAGGAG 
ATGGAGTTGA CACTTGTTGG GCTCCAAAAC TCTGGAAAAA CGACATTTGT CAATGTTATT 
GCTAGCGGCC AATTCACAGA AGATATGATC CCAACAGTCG GATTCAATAT GCGGAAGATC 
ACCAAAGGCA ACGTGACGAT CAAATTATGG GATATCGGGG GCCAGCCACG GTTCCGCTCG 
ATGTGGGAAC GATATTGCCG CGGTGTCAAC GCCATCGTCT TCATGGTGGA CGCTGCCGAC 
GAGGAGAAGC TCGAAGCATC CAGAAATGAG CTTATGCAGC TGTTGGACAA GCCACAGCTC 
GACGCTATTC CAGTTTTGGT GCTCGGAAAC AAGAAGGATT TGCCTGGAGC ACTTGATGAG 
CGGCAATTGA TCGAAAGAAT GAATCTGTCA TCAATCCAGA ATCGCGAGAT TTGCTGCTAT 
TCTATTTCAT GCAAAGAGAA GGAGAATATT GATATCACCC TCCAATGGCT CATCGATCAC 
TCGAAAGCTC AACGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_502791.1
CDS	31..588
Translation	MLAMVNKVLDWIRSLFWKEEMELTLVGLQNSGKTTFVNVIASGQFTEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVNAIVFMVDAADEEKLEASRNELMQLLDKPQLDAIPVLVLGNKKDLPGALDERQLIERMNLSSIQNREICCYSISCKEKENIDITLQWLIDHSKAQR

Target ORF information:

RefSeq Version	NM_070390.7
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans ARF-Like (arl-8), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_070390.7

ORF Insert Sequence:

ATGTTGGCTA TGGTGAATAA GGTTCTCGAC TGGATTCGCA GTCTTTTTTG GAAAGAGGAG 
ATGGAGTTGA CACTTGTTGG GCTCCAAAAC TCTGGAAAAA CGACATTTGT CAATGTTATT 
GCTAGCGGCC AATTCACAGA AGATATGATC CCAACAGTCG GATTCAATAT GCGGAAGATC 
ACCAAAGGCA ACGTGACGAT CAAATTATGG GATATCGGGG GCCAGCCACG GTTCCGCTCG 
ATGTGGGAAC GATATTGCCG CGGTGTCAAC GCCATCGTCT TCATGGTGGA CGCTGCCGAC 
GAGGAGAAGC TCGAAGCATC CAGAAATGAG CTTATGCAGC TGTTGGACAA GCCACAGCTC 
GACGCTATTC CAGTTTTGGT GCTCGGAAAC AAGAAGGATT TGCCTGGAGC ACTTGATGAG 
CGGCAATTGA TCGAAAGAAT GAATCTGTCA TCAATCCAGA ATCGCGAGAT TTGCTGCTAT 
TCTATTTCAT GCAAAGAGAA GGAGAATATT GATATCACCC TCCAATGGCT CATCGATCAC 
TCGAAAGCTC AACGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

arl-8 ( NM_070390.6 ) cDNA ORF clone, Caenorhabditis elegans -> NP_502791.1 Caenorhabditis elegans ARF-Like (arl-8), partial mRNA.

Price & Availability↑

CloneID	OCa342750
Clone ID Related Accession (Same CDS sequence)	NM_070390.7 , NM_070390.6
Accession Version	NM_070390.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 558bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Caenorhabditis elegans
Product	ARF-Like
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_070390.5. COMPLETENESS: incomplete on both ends.

ATGTTGGCTA TGGTGAATAA GGTTCTCGAC TGGATTCGCA GTCTTTTTTG GAAAGAGGAG 
ATGGAGTTGA CACTTGTTGG GCTCCAAAAC TCTGGAAAAA CGACATTTGT CAATGTTATT 
GCTAGCGGCC AATTCACAGA AGATATGATC CCAACAGTCG GATTCAATAT GCGGAAGATC 
ACCAAAGGCA ACGTGACGAT CAAATTATGG GATATCGGGG GCCAGCCACG GTTCCGCTCG 
ATGTGGGAAC GATATTGCCG CGGTGTCAAC GCCATCGTCT TCATGGTGGA CGCTGCCGAC 
GAGGAGAAGC TCGAAGCATC CAGAAATGAG CTTATGCAGC TGTTGGACAA GCCACAGCTC 
GACGCTATTC CAGTTTTGGT GCTCGGAAAC AAGAAGGATT TGCCTGGAGC ACTTGATGAG 
CGGCAATTGA TCGAAAGAAT GAATCTGTCA TCAATCCAGA ATCGCGAGAT TTGCTGCTAT 
TCTATTTCAT GCAAAGAGAA GGAGAATATT GATATCACCC TCCAATGGCT CATCGATCAC 
TCGAAAGCTC AACGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_502791.1
CDS	1..558
Translation	MLAMVNKVLDWIRSLFWKEEMELTLVGLQNSGKTTFVNVIASGQFTEDMIPTVGFNMRKITKGNVTIKLWDIGGQPRFRSMWERYCRGVNAIVFMVDAADEEKLEASRNELMQLLDKPQLDAIPVLVLGNKKDLPGALDERQLIERMNLSSIQNREICCYSISCKEKENIDITLQWLIDHSKAQR

Target ORF information:

RefSeq Version	NM_070390.6
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans ARF-Like (arl-8), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_070390.6

ORF Insert Sequence:

ATGTTGGCTA TGGTGAATAA GGTTCTCGAC TGGATTCGCA GTCTTTTTTG GAAAGAGGAG 
ATGGAGTTGA CACTTGTTGG GCTCCAAAAC TCTGGAAAAA CGACATTTGT CAATGTTATT 
GCTAGCGGCC AATTCACAGA AGATATGATC CCAACAGTCG GATTCAATAT GCGGAAGATC 
ACCAAAGGCA ACGTGACGAT CAAATTATGG GATATCGGGG GCCAGCCACG GTTCCGCTCG 
ATGTGGGAAC GATATTGCCG CGGTGTCAAC GCCATCGTCT TCATGGTGGA CGCTGCCGAC 
GAGGAGAAGC TCGAAGCATC CAGAAATGAG CTTATGCAGC TGTTGGACAA GCCACAGCTC 
GACGCTATTC CAGTTTTGGT GCTCGGAAAC AAGAAGGATT TGCCTGGAGC ACTTGATGAG 
CGGCAATTGA TCGAAAGAAT GAATCTGTCA TCAATCCAGA ATCGCGAGAT TTGCTGCTAT 
TCTATTTCAT GCAAAGAGAA GGAGAATATT GATATCACCC TCCAATGGCT CATCGATCAC 
TCGAAAGCTC AACGCTAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

arl-8 cDNA ORF clone, Caenorhabditis elegans

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報