Gene Symbol | mttu-1 |
Entrez Gene ID | 178038 |
Full Name | Probable mitochondrial tRNA-specific 2-thiouridylase 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » mttu-1 cDNA ORF clone
Gene Symbol | mttu-1 |
Entrez Gene ID | 178038 |
Full Name | Probable mitochondrial tRNA-specific 2-thiouridylase 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_069719.3 | NP_502120.1 | Probable mitochondrial tRNA-specific 2-thiouridylase 1 |
NM_069719.4 | NP_502120.1 | Probable mitochondrial tRNA-specific 2-thiouridylase 1 |
Homo sapiens (human) | TRMU | NP_060476.2 |
Mus musculus (house mouse) | Trmu | NP_082339.1 |
Schizosaccharomyces pombe (fission yeast) | SPAC23H4.04 | NP_593402.1 |
Oryza sativa (rice) | Os03g0174600 | NP_001049129.1 |
Drosophila melanogaster (fruit fly) | CG3021 | NP_652639.1 |
Caenorhabditis elegans (roundworm) | B0035.16 | NP_502120.1 |
Kluyveromyces lactis | KLLA0F24706g | XP_456180.1 |
Arabidopsis thaliana (thale cress) | AT1G51310 | NP_175542.2 |
Pan troglodytes (chimpanzee) | TRMU | XP_515202.3 |
TRMU | XP_001111019.1 | |
Rattus norvegicus (Norway rat) | Trmu | NP_001129348.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP011960 | XP_320574.3 |
Saccharomyces cerevisiae (baker's yeast) | SLM3 | NP_010251.1 |
Eremothecium gossypii | AGOS_AEL087C | NP_984774.2 |
Canis lupus familiaris (dog) | TRMU | XP_538325.2 |
Bos taurus (cattle) | TRMU | NP_001156660.1 |
Gallus gallus (chicken) | TRMU | NP_001026522.1 |
Danio rerio (zebrafish) | trmu | NP_001018435.1 |
Xenopus tropicalis (tropical clawed frog) | trmu | XP_002932238.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We further show that mtcu-1; mttu-1 and mtcu-2; mttu-1 double mutants display severe growth defects and sterility. The animal models presented here support the idea that the pathological states in humans may initially develop not as a direct consequence of a bioenergetic defect, but from the cell's maladaptive response to the hypomodification status of mt-tRNAs
Title: Mutations in the Caenorhabditis elegans orthologs of human genes required for mitochondrial tRNA modification cause similar electron transport chain defects but different nuclear responses.
The following mttu-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the mttu-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa342309 | |
Clone ID Related Accession (Same CDS sequence) | NM_069719.3 , NM_069719.4 | |
Accession Version | NM_069719.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1128bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Probable mitochondrial tRNA-specific 2-thiouridylase 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_069719.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCCACGAG TTGTGATTGG AATGTCCGGC GGTGTGGATA GTGCTGTTTC GGCGTTTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_502120.1 |
CDS | 1..1128 |
Translation |
Target ORF information:
Target ORF information:
|
NM_069719.3 |
1 | ATGCCACGAG TTGTGATTGG AATGTCCGGC GGTGTGGATA GTGCTGTTTC GGCGTTTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342309 | |
Clone ID Related Accession (Same CDS sequence) | NM_069719.3 , NM_069719.4 | |
Accession Version | NM_069719.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1128bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Probable mitochondrial tRNA-specific 2-thiouridylase 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_069719.3. |
1 | ATGCCACGAG TTGTGATTGG AATGTCCGGC GGTGTGGATA GTGCTGTTTC GGCGTTTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_502120.1 |
CDS | 7..1134 |
Translation |
Target ORF information:
Target ORF information:
|
NM_069719.4 |
1 | ATGCCACGAG TTGTGATTGG AATGTCCGGC GGTGTGGATA GTGCTGTTTC GGCGTTTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |