Gene Symbol | lgg-2 |
Entrez Gene ID | 177989 |
Full Name | Protein lgg |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » lgg-2 cDNA ORF clone
Gene Symbol | lgg-2 |
Entrez Gene ID | 177989 |
Full Name | Protein lgg |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001268595.1 | NP_001255524.1 | Protein lgg |
NM_001268595.2 | NP_001255524.1 | Protein lgg |
NM_001268594.3 | NP_001255523.2 | Protein lgg-2 |
NM_001268594.2 | NP_001255523.2 | Protein lgg-2 |
MAP1LC3A | XP_001104172.1 | |
Caenorhabditis elegans (roundworm) | lgg-2 | NP_001255523.1 |
Rattus norvegicus (Norway rat) | Map1lc3a | NP_955794.1 |
Gallus gallus (chicken) | MAP1LC3A | XP_417327.2 |
Danio rerio (zebrafish) | map1lc3a | NP_999904.1 |
Homo sapiens (human) | MAP1LC3A | NP_115903.1 |
Canis lupus familiaris (dog) | MAP1LC3A | XP_863854.1 |
Pan troglodytes (chimpanzee) | MAP1LC3A | XP_001159668.1 |
Bos taurus (cattle) | MAP1LC3A | NP_001039640.1 |
Mus musculus (house mouse) | Map1lc3a | NP_080011.1 |
Xenopus tropicalis (tropical clawed frog) | map1lc3a | NP_001007979.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Data show the N-terminal of LGG-1 and LGG-2 adopts the closed and open form, respectively. They have distinct binding pockets that prefer different residues, influencing binding specificity and differential interaction with autophagy proteins.
Title: Structural Basis of the Differential Function of the Two C. elegans Atg8 Homologs, LGG-1 and LGG-2, in Autophagy.
the major contribution of LGG-2 in sperm-inherited organelle clearance resides in its capacity to mediate the retrograde transport of autophagosomes rather than their fusion with acidic compartments.
Title: Sperm-inherited organelle clearance in C. elegans relies on LC3-dependent autophagosome targeting to the pericentrosomal area.
LGG-2 interacts with VPS-39 to tether autophagosomes and lysosomes.
Title: The C. elegans LC3 acts downstream of GABARAP to degrade autophagosomes by interacting with the HOPS subunit VPS39.
both LGG-2 and LGG-1 act synergistically and are involved in dauer formation and longevity of the worm.
Title: The autophagosomal protein LGG-2 acts synergistically with LGG-1 in dauer formation and longevity in C. elegans.
The following lgg-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lgg-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa342281 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268594.3 , NM_001268594.2 | |
Accession Version | NM_001268594.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein lgg-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001268594.2. |
1 | ATGCTAGCCA CGCTTCAAAG TTACACACAA ACAGCGATGA GCGGAAATCG GGGAGGATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255523.2 |
CDS | 54..482 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268594.3 |
1 | ATGCTAGCCA CGCTTCAAAG TTACACACAA ACAGCGATGA GCGGAAATCG GGGAGGATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342281 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268594.3 , NM_001268594.2 | |
Accession Version | NM_001268594.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 429bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein lgg-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Aug 25, 2015 this sequence version replaced NM_001268594.1. COMPLETENESS: incomplete on both ends. |
1 | ATGCTAGCCA CGCTTCAAAG TTACACACAA ACAGCGATGA GCGGAAATCG GGGAGGATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255523.2 |
CDS | 1..429 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268594.2 |
1 | ATGCTAGCCA CGCTTCAAAG TTACACACAA ACAGCGATGA GCGGAAATCG GGGAGGATCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342869 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268595.1 , NM_001268595.2 | |
Accession Version | NM_001268595.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 225bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Protein lgg | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGGATCGCT GCAAATTCCT AGTACCCGAG CATATAACCG TTGCCGAGCT CATGTCAATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255524.1 |
CDS | 1..225 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268595.1 |
1 | ATGGATCGCT GCAAATTCCT AGTACCCGAG CATATAACCG TTGCCGAGCT CATGTCAATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa342869 | |
Clone ID Related Accession (Same CDS sequence) | NM_001268595.1 , NM_001268595.2 | |
Accession Version | NM_001268595.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 225bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein lgg | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001268595.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGGATCGCT GCAAATTCCT AGTACCCGAG CATATAACCG TTGCCGAGCT CATGTCAATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001255524.1 |
CDS | 1..225 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001268595.2 |
1 | ATGGATCGCT GCAAATTCCT AGTACCCGAG CATATAACCG TTGCCGAGCT CATGTCAATT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |