Gene Symbol | pmk-3 |
Entrez Gene ID | 177610 |
Full Name | Mitogen-activated protein kinase pmk-3 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pmk-3 cDNA ORF clone
Gene Symbol | pmk-3 |
Entrez Gene ID | 177610 |
Full Name | Mitogen-activated protein kinase pmk-3 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_068962.5 | NP_501363.1 | Mitogen-activated protein kinase pmk-3 |
NM_068962.4 | NP_501363.1 | Mitogen-activated protein kinase pmk-3 |
NM_001307276.1 | NP_001294205.1 | Mitogen-activated protein kinase pmk-3 |
NM_001307276.2 | NP_001294205.1 | Protein kinase domain-containing protein |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
cytosol-localized HSP-60 physically binds and stabilizes SEK-1/MAP kinase kinase 3, which in turn up-regulates p38 MAP kinase and increases immunity.
Title: Mitochondrial chaperone HSP-60 regulates anti-bacterial immunity via p38 MAP kinase signaling.
ribosomal inactivation-induced iron accumulation in Caenorhabditis elegans as a simplified in vivo model for gut nutrition uptake was dependent on SEK-1, a p38 kinase activator, leading to suppression of FPN-1.1 expression and iron accumulation.
Title: Non-mutagenic Suppression of Enterocyte Ferroportin 1 by Chemical Ribosomal Inactivation via p38 Mitogen-activated Protein Kinase (MAPK)-mediated Regulation: EVIDENCE FOR ENVIRONMENTAL HEMOCHROMATOSIS.
The p38MAPK/ATF-7 immune pathway is triggered by mitochondrial complex I dysfunction.
Title: The Mitochondria-Regulated Immune Pathway Activated in the C.?elegans Intestine Is Neuroprotective.
DLK-1, SEK-3 and PMK-3 have roles in C. elegans adaptation to disruption of the mitochondrial electron transport chain, and in extended lifespan
Title: DLK-1, SEK-3 and PMK-3 Are Required for the Life Extension Induced by Mitochondrial Bioenergetic Disruption in C. elegans.
Mutants lacking p38 MAPK components pmk-1 or sek-1 resemble mutants lacking the hypoxia response component and prolyl hydroxylase egl-9, with impaired subcellular localization of Mint orthologue LIN-10, internalization of glutamate receptor GLR-1, and depression of GLR-1-mediated behaviors.
Title: The p38 MAP kinase pathway modulates the hypoxia response and glutamate receptor trafficking in aging neurons.
The following pmk-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pmk-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa343292 | |
Clone ID Related Accession (Same CDS sequence) | NM_068962.5 , NM_068962.4 | |
Accession Version | NM_068962.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Mitogen-activated protein kinase pmk-3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_068962.4. |
1 | ATGGCGTCAG TCCCATCGTC ATCTAGTCTC CCAGTGTCGC ATGTCCGTCG TCATGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_501363.1 |
CDS | 85..1509 |
Translation |
Target ORF information:
Target ORF information:
|
NM_068962.5 |
1 | ATGGCGTCAG TCCCATCGTC ATCTAGTCTC CCAGTGTCGC ATGTCCGTCG TCATGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343292 | |
Clone ID Related Accession (Same CDS sequence) | NM_068962.5 , NM_068962.4 | |
Accession Version | NM_068962.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1425bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Mitogen-activated protein kinase pmk-3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_068962.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGCGTCAG TCCCATCGTC ATCTAGTCTC CCAGTGTCGC ATGTCCGTCG TCATGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_501363.1 |
CDS | 1..1425 |
Translation |
Target ORF information:
Target ORF information:
|
NM_068962.4 |
1 | ATGGCGTCAG TCCCATCGTC ATCTAGTCTC CCAGTGTCGC ATGTCCGTCG TCATGAAGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343471 | |
Clone ID Related Accession (Same CDS sequence) | NM_001307276.1 , NM_001307276.2 | |
Accession Version | NM_001307276.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Mitogen-activated protein kinase pmk-3 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGAGACATG ACAATATCAT CTGTGCTCTT GACATCTACA CACCTGACGA GGAAAACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001294205.1 |
CDS | 1..903 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001307276.1 |
1 | ATGAGACATG ACAATATCAT CTGTGCTCTT GACATCTACA CACCTGACGA GGAAAACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa343471 | |
Clone ID Related Accession (Same CDS sequence) | NM_001307276.1 , NM_001307276.2 | |
Accession Version | NM_001307276.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 903bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Protein kinase domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001307276.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGAGACATG ACAATATCAT CTGTGCTCTT GACATCTACA CACCTGACGA GGAAAACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001294205.1 |
CDS | 1..903 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001307276.2 |
1 | ATGAGACATG ACAATATCAT CTGTGCTCTT GACATCTACA CACCTGACGA GGAAAACGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |