Gene Symbol | eri-1 |
Entrez Gene ID | 176868 |
Full Name | 3'-5' exonuclease eri-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » eri-1 cDNA ORF clone
Gene Symbol | eri-1 |
Entrez Gene ID | 176868 |
Full Name | 3'-5' exonuclease eri-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_171244.4 | NP_741292.1 | 3'-5' exonuclease eri-1 |
NM_171245.4 | NP_741293.1 | 3'-5' exonuclease eri-1 |
NM_171245.5 | NP_741293.1 | 3'-5' exonuclease eri-1 |
NM_001307716.2 | NP_001294645.1 | Exonuclease domain-containing protein |
NM_001307717.1 | NP_001294646.1 | 3'-5' exonuclease eri-1 |
NM_171244.5 | NP_741292.1 | 3'-5' exonuclease eri-1 |
NM_001307717.2 | NP_001294646.1 | Exonuclease domain-containing protein |
NM_001307716.1 | NP_001294645.1 | 3'-5' exonuclease eri-1 |
Bos taurus (cattle) | ERI1 | XP_002699843.1 |
Schizosaccharomyces pombe (fission yeast) | eri1 | XP_001713129.1 |
LOC699381 | XP_002805307.1 | |
Canis lupus familiaris (dog) | ERI1 | XP_539997.2 |
Gallus gallus (chicken) | ERI1 | NP_001006450.1 |
Danio rerio (zebrafish) | eri1 | NP_001018450.1 |
Caenorhabditis elegans (roundworm) | eri-1 | NP_741293.1 |
Pan troglodytes (chimpanzee) | ERI1 | XP_001136735.1 |
Mus musculus (house mouse) | Eri1 | NP_080343.4 |
Rattus norvegicus (Norway rat) | Eri1 | NP_001014165.1 |
Xenopus tropicalis (tropical clawed frog) | eri1 | NP_001016146.1 |
Homo sapiens (human) | ERI1 | NP_699163.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
In the absence of eri-1, reserpine mediated lifespan extension (RMLE) is shortened. In the dop-3 loss-of-function background, lack of eri-1 completely abolishes RMLE. This suggests that dop-3 and eri-1 act in independent parallel pathways for RMLE and these two pathways are essential and sufficient for the longevity enhancement by reserpine in C. elegans.
Title: Reserpine requires the D2-type receptor,
results identify novel components of the endo RNAi machinery, demonstrate differential requirements for the Eri factors in the sperm-producing germline, and begin to delineate the functional requirement for the ERI/DICER complex in sperm development
Title: Requirement for the ERI/DICER complex in endogenous RNA interference and sperm development in Caenorhabditis elegans.
In C. elegans, two protein isoforms of ERI-1 are localized to the cytoplasm, and each has distinct functions in ribosomal RNA processing and negative regulation of RNA interference.
Title: The exonuclease ERI-1 has a conserved dual role in 5.8S rRNA processing and RNAi.
These results provide additional support for the hypothesis that RRF-3 and ERI-1 act together in the endo-siRNA pathway, and furthermore suggests their involvement in additional biological processes.
Title: Whole genome microarray analysis of C. elegans rrf-3 and eri-1 mutants.
Feeding unc-13 & eri-1 strains dsRNA corresponding to a neuronally expressed GFP reporter resulted in reduction of GFP in double mutants compared to GFP expression in eri-1 mutants, indicating that UNC-13 functions in conjunction with ERI-1 in RNAi.
Title: Synaptic neurotransmission protein UNC-13 affects RNA interference in neurons.
The following eri-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the eri-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa344144 | |
Clone ID Related Accession (Same CDS sequence) | NM_171245.4 , NM_171245.5 | |
Accession Version | NM_171245.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | 3'-5' exonuclease eri-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_171245.3. COMPLETENESS: incomplete on both ends. |
1 | ATGAGCGCAG ATGAGCCGTC TCCAGAAGAC GAAAAATATC TGGAAAGTCT ACGAGATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741293.1 |
CDS | 1..1347 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171245.4 |
1 | ATGAGCGCAG ATGAGCCGTC TCCAGAAGAC GAAAAATATC TGGAAAGTCT ACGAGATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344144 | |
Clone ID Related Accession (Same CDS sequence) | NM_171245.4 , NM_171245.5 | |
Accession Version | NM_171245.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1347bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | 3'-5' exonuclease eri-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_171245.4. |
1 | ATGAGCGCAG ATGAGCCGTC TCCAGAAGAC GAAAAATATC TGGAAAGTCT ACGAGATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741293.1 |
CDS | 8..1354 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171245.5 |
1 | ATGAGCGCAG ATGAGCCGTC TCCAGAAGAC GAAAAATATC TGGAAAGTCT ACGAGATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344630 | |
Clone ID Related Accession (Same CDS sequence) | NM_001307716.2 , NM_001307716.1 | |
Accession Version | NM_001307716.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Exonuclease domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001307716.1. |
1 | ATGCAGTTTA CCAAAATTGC CCAAGAAACA GTCGATGCTG CTCCATATTT CCGAGAGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001294645.1 |
CDS | 363..1091 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001307716.2 |
1 | ATGCAGTTTA CCAAAATTGC CCAAGAAACA GTCGATGCTG CTCCATATTT CCGAGAGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344630 | |
Clone ID Related Accession (Same CDS sequence) | NM_001307716.2 , NM_001307716.1 | |
Accession Version | NM_001307716.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 729bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | 3'-5' exonuclease eri-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGCAGTTTA CCAAAATTGC CCAAGAAACA GTCGATGCTG CTCCATATTT CCGAGAGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001294645.1 |
CDS | 1..729 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001307716.1 |
1 | ATGCAGTTTA CCAAAATTGC CCAAGAAACA GTCGATGCTG CTCCATATTT CCGAGAGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344631 | |
Clone ID Related Accession (Same CDS sequence) | NM_001307717.1 , NM_001307717.2 | |
Accession Version | NM_001307717.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | 3'-5' exonuclease eri-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). COMPLETENESS: incomplete on both ends. |
1 | ATGCAGTTTA CCAAAATTGC CCAAGAAACA GTCGATGCTG CTCCATATTT CCGAGAGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001294646.1 |
CDS | 1..1131 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001307717.1 |
1 | ATGCAGTTTA CCAAAATTGC CCAAGAAACA GTCGATGCTG CTCCATATTT CCGAGAGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344631 | |
Clone ID Related Accession (Same CDS sequence) | NM_001307717.1 , NM_001307717.2 | |
Accession Version | NM_001307717.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1131bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Exonuclease domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_001307717.1. |
1 | ATGCAGTTTA CCAAAATTGC CCAAGAAACA GTCGATGCTG CTCCATATTT CCGAGAGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001294646.1 |
CDS | 363..1493 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001307717.2 |
1 | ATGCAGTTTA CCAAAATTGC CCAAGAAACA GTCGATGCTG CTCCATATTT CCGAGAGGCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344145 | |
Clone ID Related Accession (Same CDS sequence) | NM_171244.4 , NM_171244.5 | |
Accession Version | NM_171244.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | 3'-5' exonuclease eri-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Jun 26, 2012 this sequence version replaced NM_171244.3. COMPLETENESS: incomplete on both ends. |
1 | ATGAGCGCAG ATGAGCCGTC TCCAGAAGAC GAAAAATATC TGGAAAGTCT ACGAGATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741292.1 |
CDS | 1..1749 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171244.4 |
1 | ATGAGCGCAG ATGAGCCGTC TCCAGAAGAC GAAAAATATC TGGAAAGTCT ACGAGATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa344145 | |
Clone ID Related Accession (Same CDS sequence) | NM_171244.4 , NM_171244.5 | |
Accession Version | NM_171244.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1749bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | 3'-5' exonuclease eri-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003282). On Sep 4, 2019 this sequence version replaced NM_171244.4. |
1 | ATGAGCGCAG ATGAGCCGTC TCCAGAAGAC GAAAAATATC TGGAAAGTCT ACGAGATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_741292.1 |
CDS | 8..1756 |
Translation |
Target ORF information:
Target ORF information:
|
NM_171244.5 |
1 | ATGAGCGCAG ATGAGCCGTC TCCAGAAGAC GAAAAATATC TGGAAAGTCT ACGAGATTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |