| Gene Symbol | CUL-2 |
| Entrez Gene ID | 176806 |
| Full Name | Cullin-2 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » CUL-2 cDNA ORF clone
| Gene Symbol | CUL-2 |
| Entrez Gene ID | 176806 |
| Full Name | Cullin-2 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_001027838.2 | NP_001023009.1 | Cullin-2 |
| NM_001027837.1 | NP_001023008.1 | Cullin-2 |
| NM_001027837.2 | NP_001023008.1 | Cullin-2 |
| NM_001027838.3 | NP_001023009.1 | Cullin-2 |
| NM_001027836.3 | NP_001023007.1 | Cullin-2 |
| NM_001027836.2 | NP_001023007.1 | Cullin-2 |
| NM_067424.4 | NP_499825.3 | Cullin-2 |
| Bos taurus (cattle) | CUL2 | NP_001070377.1 |
| Homo sapiens (human) | CUL2 | NP_001185707.1 |
| Canis lupus familiaris (dog) | CUL2 | XP_005616994.1 |
| Rattus norvegicus (Norway rat) | Cul2 | NP_001101887.1 |
| Gallus gallus (chicken) | CUL2 | NP_001026141.1 |
| CUL2 | XP_001087735.2 | |
| Danio rerio (zebrafish) | cul2 | XP_002666627.1 |
| Drosophila melanogaster (fruit fly) | Cul-2 | NP_724352.1 |
| Pan troglodytes (chimpanzee) | CUL2 | XP_003312567.1 |
| Mus musculus (house mouse) | Cul2 | NP_083678.2 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP003605 | XP_313365.4 |
| Caenorhabditis elegans (roundworm) | cul-2 | NP_499825.3 |
| Xenopus tropicalis (tropical clawed frog) | cul2 | XP_002935209.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
CUL-2(LRR-1) and UBXN-3 drive replisome disassembly during DNA replication termination and mitosis.
Title: CUL-2
CUL-2 RING E3 ubiquitin-ligase acts at multiple levels to control germline development; CUL-2 may similarly regulate germline development in other organisms as well.
Title: CRL2(LRR-1) E3-ligase regulates proliferation and progression through meiosis in the Caenorhabditis elegans germline.
Results indicate that LRR-1 acts as a nuclear substrate-recognition subunit of a Cullin 2-RING E3 ligase complex (CRL2(LRR-1)), which ensures DNA replication integrity.
Title: The CRL2LRR-1 ubiquitin ligase regulates cell cycle progression during C. elegans development.
The C. elegans p97/CDC-48-UFD-1-NPL-4 complex controls the sperm-oocyte switch by regulating CUL-2-mediated TRA-1A proteasome degradation.
Title: Caenorhabditis elegans p97 controls germline-specific sex determination by controlling the TRA-1 level in a CUL-2-dependent manner.
MEL-26 levels are kept low by the action of another type of ubiquitin ligase, which contains CUL-2
Title: Levels of the ubiquitin ligase substrate adaptor MEL-26 are inversely correlated with MEI-1/katanin microtubule-severing activity during both meiosis and mitosis.
The following CUL-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CUL-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa340278 | |
| Clone ID Related Accession (Same CDS sequence) | NM_067424.4 | |
| Accession Version | NM_067424.4 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2553bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2017-04-12 | |
| Organism | Caenorhabditis elegans | |
| Product | Cullin-2 | |
| Comment | REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_067424.3. COMPLETENESS: incomplete on both ends. | |
1 | ATGACGTTCA ATATATTTTT AACCTTCTCC ACCATATCCC CGAAAATCTT CAGTGTAACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_499825.3 |
| CDS | 1..2553 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_067424.4 |
1 | ATGACGTTCA ATATATTTTT AACCTTCTCC ACCATATCCC CGAAAATCTT CAGTGTAACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa340279 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001027837.1 , NM_001027837.2 | |
| Accession Version | NM_001027837.1 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Cullin-2 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). COMPLETENESS: incomplete on both ends. | |
1 | ATGGCAAGTT CCACAAAAGT TTCCTTACGT CGTCCACCTC GTCCACAGGT TATGTACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001023008.1 |
| CDS | 1..2376 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001027837.1 |
1 | ATGGCAAGTT CCACAAAAGT TTCCTTACGT CGTCCACCTC GTCCACAGGT TATGTACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa340279 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001027837.1 , NM_001027837.2 | |
| Accession Version | NM_001027837.2 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2376bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Cullin-2 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001027837.1. | |
1 | ATGGCAAGTT CCACAAAAGT TTCCTTACGT CGTCCACCTC GTCCACAGGT TATGTACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001023008.1 |
| CDS | 13..2388 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001027837.2 |
1 | ATGGCAAGTT CCACAAAAGT TTCCTTACGT CGTCCACCTC GTCCACAGGT TATGTACTCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa340280 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001027836.3 , NM_001027836.2 | |
| Accession Version | NM_001027836.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2325bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Cullin-2 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001027836.2. | |
1 | ATGTACTCAC TGAAGCCAAA AGTTGTGGAA TTTGACAAAG TATGGGTGCA GTTGAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001023007.1 |
| CDS | 206..2530 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001027836.3 |
1 | ATGTACTCAC TGAAGCCAAA AGTTGTGGAA TTTGACAAAG TATGGGTGCA GTTGAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa340280 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001027836.3 , NM_001027836.2 | |
| Accession Version | NM_001027836.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2325bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Cullin-2 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001027836.1. COMPLETENESS: incomplete on both ends. | |
1 | ATGTACTCAC TGAAGCCAAA AGTTGTGGAA TTTGACAAAG TATGGGTGCA GTTGAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001023007.1 |
| CDS | 1..2325 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001027836.2 |
1 | ATGTACTCAC TGAAGCCAAA AGTTGTGGAA TTTGACAAAG TATGGGTGCA GTTGAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa340281 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001027838.2 , NM_001027838.3 | |
| Accession Version | NM_001027838.2 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2232bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Cullin-2 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001027838.1. COMPLETENESS: incomplete on both ends. | |
1 | ATGTACTCAC TGAAGCCAAA AGTTGTGGAA TTTGACAAAG TATGGGTGCA GTTGAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001023009.1 |
| CDS | 1..2232 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001027838.2 |
1 | ATGTACTCAC TGAAGCCAAA AGTTGTGGAA TTTGACAAAG TATGGGTGCA GTTGAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa340281 | |
| Clone ID Related Accession (Same CDS sequence) | NM_001027838.2 , NM_001027838.3 | |
| Accession Version | NM_001027838.3 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 2232bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Cullin-2 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001027838.2. | |
1 | ATGTACTCAC TGAAGCCAAA AGTTGTGGAA TTTGACAAAG TATGGGTGCA GTTGAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_001023009.1 |
| CDS | 206..2437 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_001027838.3 |
1 | ATGTACTCAC TGAAGCCAAA AGTTGTGGAA TTTGACAAAG TATGGGTGCA GTTGAGACCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |