Gene Symbol | dpy-18 |
Entrez Gene ID | 176569 |
Full Name | Prolyl 4-hydroxylase subunit alpha-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » dpy-18 cDNA ORF clone
Gene Symbol | dpy-18 |
Entrez Gene ID | 176569 |
Full Name | Prolyl 4-hydroxylase subunit alpha-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_067063.3 | NP_499464.1 | Prolyl 4-hydroxylase subunit alpha-1 |
NM_067063.4 | NP_499464.1 | Prolyl 4-hydroxylase subunit alpha-1 |
Canis lupus familiaris (dog) | P4HA1 | XP_005619064.1 |
Bos taurus (cattle) | P4HA1 | NP_001069238.1 |
Danio rerio (zebrafish) | p4ha1a | NP_001038463.1 |
Drosophila melanogaster (fruit fly) | PH4alphaEFB | NP_733371.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000971 | XP_309164.4 |
Rattus norvegicus (Norway rat) | P4ha1 | NP_742059.2 |
Caenorhabditis elegans (roundworm) | dpy-18 | NP_499464.1 |
Xenopus tropicalis (tropical clawed frog) | LOC100490484 | XP_002936004.1 |
P4HA1 | XP_001103971.2 | |
Xenopus tropicalis (tropical clawed frog) | p4ha1 | XP_004915844.1 |
Homo sapiens (human) | P4HA1 | NP_001136067.1 |
Mus musculus (house mouse) | P4ha1 | NP_035160.1 |
Danio rerio (zebrafish) | LOC556879 | XP_005156147.1 |
Caenorhabditis elegans (roundworm) | phy-2 | NP_502317.1 |
Pan troglodytes (chimpanzee) | P4HA1 | XP_001140652.1 |
Gallus gallus (chicken) | P4HA1 | NP_001185667.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
data suggest that DPY-18 regulates ephrin expression to direct axon guidance, a role for P4Hs that may be conserved in higher organisms.
Title: Regulation of axonal midline guidance by prolyl 4-hydroxylation in Caenorhabditis elegans.
although collagen P4Hs, PHY-1/PHY-2/(PDI)(2) mixed tetramer and PHY/PDI dimers, do not act on peptide substrates by a processive mechanism, prevention of hydroxylation at one catalytic site in the tetramer impairs the function of the other catalytic site
Title: Collagen prolyl 4-hydroxylase tetramers and dimers show identical decreases in Km values for peptide substrates with increasing chain length: mutation of one of the two catalytic sites in the tetramer inactivates the enzyme by more than half.
The following dpy-18 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the dpy-18 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340458 | |
Clone ID Related Accession (Same CDS sequence) | NM_067063.3 , NM_067063.4 | |
Accession Version | NM_067063.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Prolyl 4-hydroxylase subunit alpha-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_067063.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCGCCTGG CACTCCTTGT ACTAGCCACA ATCGGCTATG CAGTTGCCGA TCTGTTCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499464.1 |
CDS | 1..1680 |
Translation |
Target ORF information:
Target ORF information:
|
NM_067063.3 |
1 | ATGCGCCTGG CACTCCTTGT ACTAGCCACA ATCGGCTATG CAGTTGCCGA TCTGTTCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340458 | |
Clone ID Related Accession (Same CDS sequence) | NM_067063.3 , NM_067063.4 | |
Accession Version | NM_067063.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1680bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Prolyl 4-hydroxylase subunit alpha-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_067063.3. |
1 | ATGCGCCTGG CACTCCTTGT ACTAGCCACA ATCGGCTATG CAGTTGCCGA TCTGTTCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_499464.1 |
CDS | 2..1681 |
Translation |
Target ORF information:
Target ORF information:
|
NM_067063.4 |
1 | ATGCGCCTGG CACTCCTTGT ACTAGCCACA ATCGGCTATG CAGTTGCCGA TCTGTTCACC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |