Gene Symbol | pat-2 |
Entrez Gene ID | 176240 |
Full Name | Integrin alpha pat-2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pat-2 cDNA ORF clone
Gene Symbol | pat-2 |
Entrez Gene ID | 176240 |
Full Name | Integrin alpha pat-2 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_066547.3 | NP_498948.1 | Integrin alpha pat-2 |
NM_066547.4 | NP_498948.1 | Integrin alpha pat-2 |
Gallus gallus (chicken) | ITGA8 | NP_990619.1 |
Caenorhabditis elegans (roundworm) | pat-2 | NP_498948.1 |
Pan troglodytes (chimpanzee) | ITGA8 | XP_507671.2 |
Bos taurus (cattle) | ITGA8 | XP_002692127.1 |
ITGA8 | XP_001089317.1 | |
Drosophila melanogaster (fruit fly) | if | NP_001162778.1 |
Canis lupus familiaris (dog) | ITGA8 | XP_005617255.1 |
Mus musculus (house mouse) | Itga8 | NP_001001309.1 |
Homo sapiens (human) | ITGA8 | NP_003629.1 |
Rattus norvegicus (Norway rat) | Itga8 | NP_001167443.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000032 | XP_311131.5 |
Xenopus tropicalis (tropical clawed frog) | itga8 | XP_002939074.2 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Taken together, the cytoplasmic tails of alpha integrins can bypass signaling from members of the Rho family of GTPases during development.
Title: ? integrin cytoplasmic tails can rescue the loss of Rho-family GTPase signaling in the C. elegans somatic gonad.
The formation of such halos depends on the integrins PAT-2/PAT-3, UNC-112 and the GEF protein UIG-1, but not on the canonical ced-1/6/7 or ced-2/5/12 signaling modules
Title: Small GTPase CDC-42 promotes apoptotic cell corpse clearance in response to PAT-2 and CED-1 in C. elegans.
Our data suggest that PAT-2 functions through UIG-1 for CDC-42 activation, which in turn leads to cytoskeletal rearrangement and apoptotic cell internalization by muscle cells.
Title: Integrin ? PAT-2/CDC-42 signaling is required for muscle-mediated clearance of apoptotic cells in Caenorhabditis elegans.
down-regulation of ina-1 is necessary for distal tip cell migration cessation and the up-regulation of pat-2 is required for directionality
Title: Control of C. elegans hermaphrodite gonad size and shape by vab-3/Pax6-mediated regulation of integrin receptors.
The following pat-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pat-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341475 | |
Clone ID Related Accession (Same CDS sequence) | NM_066547.3 , NM_066547.4 | |
Accession Version | NM_066547.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3681bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Integrin alpha pat-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_066547.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCGAGAGG GTAGTTTTCC GCGAAGGATC GGCTTGCTTC TAGGCTTACT GGGCCTTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498948.1 |
CDS | 1..3681 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066547.3 |
1 | ATGCGAGAGG GTAGTTTTCC GCGAAGGATC GGCTTGCTTC TAGGCTTACT GGGCCTTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341475 | |
Clone ID Related Accession (Same CDS sequence) | NM_066547.3 , NM_066547.4 | |
Accession Version | NM_066547.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3681bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Integrin alpha pat-2 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_066547.3. |
1 | ATGCGAGAGG GTAGTTTTCC GCGAAGGATC GGCTTGCTTC TAGGCTTACT GGGCCTTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498948.1 |
CDS | 4..3684 |
Translation |
Target ORF information:
Target ORF information:
|
NM_066547.4 |
1 | ATGCGAGAGG GTAGTTTTCC GCGAAGGATC GGCTTGCTTC TAGGCTTACT GGGCCTTTTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |