glr-1 cDNA ORF clone, Caenorhabditis elegans

Gene
Clones
gRNAs

Summary

Gene Symbol	glr-1
Entrez Gene ID	176204
Full Name	Glutamate receptor 1
Gene Type	protein-coding
Organism	Caenorhabditis elegans

mRNA and Protein(s)

mRNA	Protein	Name
NM_066486.6	NP_498887.2	Glutamate receptor 1
NM_066486.7	NP_498887.2	Glutamate receptor 1

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	GRIA3	XP_003317712.1
Danio rerio (zebrafish)	gria3b	NP_938174.1
Bos taurus (cattle)	GRIA3	NP_001192988.1
Gallus gallus (chicken)	GRIA3	NP_990546.2
Xenopus tropicalis (tropical clawed frog)	gria3	NP_001106494.1
Canis lupus familiaris (dog)	GRIA3	XP_005641824.1
Drosophila melanogaster (fruit fly)	Glu-RI	NP_476855.1
Homo sapiens (human)	GRIA3	NP_015564.4
	GRIA3	XP_001088327.1
Drosophila melanogaster (fruit fly)	Glu-RIB	NP_001261622.1
Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006027	XP_316066.4
Caenorhabditis elegans (roundworm)	glr-2	NP_001021114.1
Mus musculus (house mouse)	Gria3	NP_001268858.1
Rattus norvegicus (Norway rat)	Gria3	NP_116785.2
Danio rerio (zebrafish)	gria3a	NP_938153.1
Caenorhabditis elegans (roundworm)	glr-1	NP_498887.2

Gene Ontology
Bibliography

Related articles in PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.

Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

We propose a model in which synaptic activity regulates the nuclear localization of CMK-1 to mediate a negative feedback mechanism coupling GLR-1 activity with its own transcription.
Title: The CaM Kinase CMK-1 Mediates a Negative Feedback Mechanism Coupling the C. elegans Glutamate Receptor GLR-1 with Its Own Transcription.

We also assessed ionotropic glutamate receptor GLR-1 cell-specifically within AIB and determined that GLR-1 fine-tunes AIB activity to modify locomotion following reversal events. Our research highlights that signal integration underlying the initiation and fine-tuning of backwards locomotion is AIB and NPR-9 dependent, and has demonstrated the suitability of C. elegans for analysis of multisensory integration
Title: NPR-9, a Galanin-Like G-Protein Coupled Receptor, and GLR-1 Regulate Interneuronal Circuitry Underlying Multisensory Integration of Environmental Cues in Caenorhabditis elegans.

Mutants lacking p38 MAPK components pmk-1 or sek-1 resemble mutants lacking the hypoxia response component and prolyl hydroxylase egl-9, with impaired subcellular localization of Mint orthologue LIN-10, internalization of glutamate receptor GLR-1, and depression of GLR-1-mediated behaviors.
Title: The p38 MAP kinase pathway modulates the hypoxia response and glutamate receptor trafficking in aging neurons.

WDR-20 and WDR-48 form a complex with USP-46 and stimulate the DUB to deubiquitinate and stabilize GLR-1 in vivo.
Title: The WD40-repeat proteins WDR-20 and WDR-48 bind and activate the deubiquitinating enzyme USP-46 to promote the abundance of the glutamate receptor GLR-1 in the ventral nerve cord of Caenorhabditis elegans.

glr-1 is required for long-term memory for habituation and memory for context conditioning.
Title: Genetic dissection of memory for associative and non-associative learning in Caenorhabditis elegans.

The following glr-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the glr-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCa340849	NM_066486.7 Latest version!	Caenorhabditis elegans Glutamate receptor 1 (glr-1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$475.30 $679.00
View Old Accession Versions >>
OCa340849	NM_066486.6	Caenorhabditis elegans Glutamate receptor 1 (glr-1), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$510.30 $729.00
Hide Old Accession Versions >>

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
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2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
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*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

glr-1 ( NM_066486.6 ) cDNA ORF clone, Caenorhabditis elegans -> NP_498887.2 Caenorhabditis elegans Glutamate receptor 1 (glr-1), partial mRNA.

Price & Availability↑

CloneID	OCa340849
Clone ID Related Accession (Same CDS sequence)	NM_066486.6 , NM_066486.7
Accession Version	NM_066486.6	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2889bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Caenorhabditis elegans
Product	Glutamate receptor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_066486.5. COMPLETENESS: incomplete on both ends.

ATGTTTTCTT CGTTTTCTTT TTTGAACATG TTCGGTGTTC TATTCACTGT TTTCAACTTA 
ACTGTAGTTC AACCATATCC AAGTCATATT ATTATCAAAT CATTTGGGAA CAATGAAGAA 
GTATCGAGAG TGGCTCTGAA AGCTATGGAA TACACATCTG ATCATATCAA TTCCAGAGAC 
GATGTACCGT TTAAACTTGC ATTTGACCAC CGCGTAGTTG AAGAAGGCGC TGCTGTCTCG 
TGGAACATGG TGAACGCAGT CTGTGATGAG CTTAAAGAAG GTGCAATGGC ATTACTTTCA 
AGTGTTGATG GAAAAGGAAG AGAAGGTATT CGAGGAGTAT CTGATGCACT TGAAATGCCT 
CTTGTCTCAC TGACCGCTCT ATCAAATGAT GACCATCAAC AACAACAATT CGGGAATCTT 
TTCGAAGTTT CAGTGAGACC TCCAATTAGT GAACTGCTAG CTGATTTTAT TGTTCACAAA 
GGATGGGGAG AGGTTCTGGT TTTGATTGAC CCAGTACATG CAAGCCTCCA CCTACCATCA 
CTTTGGAGAC ATCTTCGTAC TCGAACCAAT ACTTCTGTCA AAGCGTCCAT GTTCGATTTG 
CCGGCTGATG AAAAACAGTT TGAAGCGTAT TTAATGCAAT TTAATATGAT GAGAAATAAT 
GAAACAAATC GAATACTTAT CGATTGTGCA TCTCCGAAAC GACTCAAGAA ACTTCTAATT 
AATATTCGCT CGGCACAATT TAATCAGGCT AACTATCACT ATGTGCTGGC AAATTATGAT 
TTTCTTCCCT ACGACCAAGA GATGTTCCAA AATGGAAATA TCAATATATC AGGTTTCAAT 
ATAATCAATA AAGATGGAAG AGAGTATTGG TCACTAAAGA AACATTTGAA GACGTCATCT 
TCATTAGGAG GTGGAGATGA TGTTAGTGTT GAGGCAGCTG TTGGACACGA TGCAATGTTA 
GTTACGTGGC ATGGATTTGC AAAGTGCCTG CAAGCGAATG ATTCATTGTT CCATGGTACA 
TTTCGACATA GGAGATTTTT CAATCGTGGA TTTCCAGGAA TCTACTGTGA TCCTCTTTCT 
GACCGTTCTC ATCCAAATCG ACCTTTCTCT TCATTTGAGC ATGGAAAAAC AATCGGAGTT 
GCTTTTAGAA ATATGAAAAT TGGACACAAA GAGGGAACAT TAACTGGGAA TATCGAATTC 
GATCGTTTTG GAAATCGCAA GAACTTTGAT GTATCCATAG TTGACTTGGT ATCAAATACA 
AAAGCAACTT TCAATTCAAA AGAAGTATTA GCGTGGCGAC AAGGTGTTGG ATTCTTCTCA 
AATCGAACAG TTGCTCAACA TTCGAGAAAG AGTCAAAATG ATCATAAGGA TAATCAAGTG 
ATAGTGCTCA CGAATCTAGT TGCTCCATTT GTGATGATAA AACGAGAATG TTTGGAAATG 
GCAAATTTGA CAGAATGTCA GGGGAACAAT AAGTTTGAAG GATTTTGTAT CGACTTGCTG 
AAACTGTTGG CTGACAAAAT TGAGGAGTTC AATTATGAGA TCAAATTAGG AACAAAGGCG 
GGATCAAAAC AAGCTGACGG AAGCTGGGAT GGAATGATTG GAGAACTTCT GAGTGGAAGA 
GCCCATGCTG TAGTTGCATC ACTTACAATA AATCAAGAAA GAGAACGAGT CGTGGATTTT 
TCAAAACCAT TTATGACAAC TGGAATTTCA ATTATGATCA AGAAGCCTGA CAAACAAGAG 
TTTTCAGTAT TTTCCTTTAT GCAACCGCTT AGTACAGAGA TTTGGATGTA CATCATATTC 
GCGTATATTG GGGTGTCAGT AGTCATCTTT CTTGTTTCAA GGTTTTCACC GTATGAATGG 
AGAGTCGAGG AGACTTCCAG AGGAGGATTC ACTATTTCCA ACGATTTTTC TGTTTATAAT 
TGCTTATGGT TTACACTAGC AGCTTTCATG CAGCAAGGAA CTGATATTTT ACCAAGATCA 
ATTTCGGGTC GTATCGCATC TTCTGCTTGG TGGTTTTTCA CAATGATCAT CGTTTCTTCT 
TACACTGCTA ACTTGGCTGC GTTCCTAACA CTTGAAAAAA TGCAAGCTCC TATAGAAAGT 
GTTGAAGACT TGGCGAAACA GTCGAAGATT AAATACGGAA TTCAAGGTGG CGGATCGACA 
GCTTCTTTCT TCAAATATTC CTCCGTTCAA ATATATCAGA GAATGTGGAG ATATATGGAA 
TCGCAAGTTC CGCCAGTTTT TGTGGCTAGT TATGCGGAAG GAATTGAAAG AGTTCGAAGT 
CATAAAGGAA GATATGCATT TCTTTTAGAA GCAACTGCAA ATGAATATGA GAATACAAGA 
AAACCATGTG ATACAATGAA AGTTGGAGCA AATCTCAACA GTATCGGATA TGGAATAGCG 
ACACCTTTCG GCTCCGACTG GAAGGATCAT ATCAACTTGG CAATTTTAGC CCTCCAAGAA 
CGTGGTGAAC TGAAAAAGTT GGAAAACAAA TGGTGGTATG ATAGAGGACA ATGCGATGCG 
GGTATTACTG TTGACGGGTC ATCTGCTAGT TTGAATCTAT CAAAAGTTGC TGGAATATTT 
TATATTTTAA TGGGTGGTAT GGTCATTTCA ATGTTGGCTG CACTCGGGGA ATTCTTGTAT 
CGAAGTAGGA TTGAAGCGAG GAAATCTAAT TCCAATTCTA TGGTGGCGAA TTTTGCGAAA 
AATTTGAAAA GTGCATTGTC ATCTCAATTA AGATTATCAG TCGAAGGAGG TGCAGTTGCA 
CAACCAGGAT CTCAATCTCA TAATGCAATT AGAAGACAAC AGGTAGCTGC ATTCTTGCCT 
GCAAATGAAA AAGAAGCTTT CAATAATGTG GATCGACCTG CAAACACTCT CTACAACACA 
GCTGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_498887.2
CDS	1..2889
Translation	MFSSFSFLNMFGVLFTVFNLTVVQPYPSHIIIKSFGNNEEVSRVALKAMEYTSDHINSRDDVPFKLAFDHRVVEEGAAVSWNMVNAVCDELKEGAMALLSSVDGKGREGIRGVSDALEMPLVSLTALSNDDHQQQQFGNLFEVSVRPPISELLADFIVHKGWGEVLVLIDPVHASLHLPSLWRHLRTRTNTSVKASMFDLPADEKQFEAYLMQFNMMRNNETNRILIDCASPKRLKKLLINIRSAQFNQANYHYVLANYDFLPYDQEMFQNGNINISGFNIINKDGREYWSLKKHLKTSSSLGGGDDVSVEAAVGHDAMLVTWHGFAKCLQANDSLFHGTFRHRRFFNRGFPGIYCDPLSDRSHPNRPFSSFEHGKTIGVAFRNMKIGHKEGTLTGNIEFDRFGNRKNFDVSIVDLVSNTKATFNSKEVLAWRQGVGFFSNRTVAQHSRKSQNDHKDNQVIVLTNLVAPFVMIKRECLEMANLTECQGNNKFEGFCIDLLKLLADKIEEFNYEIKLGTKAGSKQADGSWDGMIGELLSGRAHAVVASLTINQERERVVDFSKPFMTTGISIMIKKPDKQEFSVFSFMQPLSTEIWMYIIFAYIGVSVVIFLVSRFSPYEWRVEETSRGGFTISNDFSVYNCLWFTLAAFMQQGTDILPRSISGRIASSAWWFFTMIIVSSYTANLAAFLTLEKMQAPIESVEDLAKQSKIKYGIQGGGSTASFFKYSSVQIYQRMWRYMESQVPPVFVASYAEGIERVRSHKGRYAFLLEATANEYENTRKPCDTMKVGANLNSIGYGIATPFGSDWKDHINLAILALQERGELKKLENKWWYDRGQCDAGITVDGSSASLNLSKVAGIFYILMGGMVISMLAALGEFLYRSRIEARKSNSNSMVANFAKNLKSALSSQLRLSVEGGAVAQPGSQSHNAIRRQQVAAFLPANEKEAFNNVDRPANTLYNTAV

Target ORF information:

RefSeq Version	NM_066486.6
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Glutamate receptor 1 (glr-1), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_066486.6

ORF Insert Sequence:

ATGTTTTCTT CGTTTTCTTT TTTGAACATG TTCGGTGTTC TATTCACTGT TTTCAACTTA 
ACTGTAGTTC AACCATATCC AAGTCATATT ATTATCAAAT CATTTGGGAA CAATGAAGAA 
GTATCGAGAG TGGCTCTGAA AGCTATGGAA TACACATCTG ATCATATCAA TTCCAGAGAC 
GATGTACCGT TTAAACTTGC ATTTGACCAC CGCGTAGTTG AAGAAGGCGC TGCTGTCTCG 
TGGAACATGG TGAACGCAGT CTGTGATGAG CTTAAAGAAG GTGCAATGGC ATTACTTTCA 
AGTGTTGATG GAAAAGGAAG AGAAGGTATT CGAGGAGTAT CTGATGCACT TGAAATGCCT 
CTTGTCTCAC TGACCGCTCT ATCAAATGAT GACCATCAAC AACAACAATT CGGGAATCTT 
TTCGAAGTTT CAGTGAGACC TCCAATTAGT GAACTGCTAG CTGATTTTAT TGTTCACAAA 
GGATGGGGAG AGGTTCTGGT TTTGATTGAC CCAGTACATG CAAGCCTCCA CCTACCATCA 
CTTTGGAGAC ATCTTCGTAC TCGAACCAAT ACTTCTGTCA AAGCGTCCAT GTTCGATTTG 
CCGGCTGATG AAAAACAGTT TGAAGCGTAT TTAATGCAAT TTAATATGAT GAGAAATAAT 
GAAACAAATC GAATACTTAT CGATTGTGCA TCTCCGAAAC GACTCAAGAA ACTTCTAATT 
AATATTCGCT CGGCACAATT TAATCAGGCT AACTATCACT ATGTGCTGGC AAATTATGAT 
TTTCTTCCCT ACGACCAAGA GATGTTCCAA AATGGAAATA TCAATATATC AGGTTTCAAT 
ATAATCAATA AAGATGGAAG AGAGTATTGG TCACTAAAGA AACATTTGAA GACGTCATCT 
TCATTAGGAG GTGGAGATGA TGTTAGTGTT GAGGCAGCTG TTGGACACGA TGCAATGTTA 
GTTACGTGGC ATGGATTTGC AAAGTGCCTG CAAGCGAATG ATTCATTGTT CCATGGTACA 
TTTCGACATA GGAGATTTTT CAATCGTGGA TTTCCAGGAA TCTACTGTGA TCCTCTTTCT 
GACCGTTCTC ATCCAAATCG ACCTTTCTCT TCATTTGAGC ATGGAAAAAC AATCGGAGTT 
GCTTTTAGAA ATATGAAAAT TGGACACAAA GAGGGAACAT TAACTGGGAA TATCGAATTC 
GATCGTTTTG GAAATCGCAA GAACTTTGAT GTATCCATAG TTGACTTGGT ATCAAATACA 
AAAGCAACTT TCAATTCAAA AGAAGTATTA GCGTGGCGAC AAGGTGTTGG ATTCTTCTCA 
AATCGAACAG TTGCTCAACA TTCGAGAAAG AGTCAAAATG ATCATAAGGA TAATCAAGTG 
ATAGTGCTCA CGAATCTAGT TGCTCCATTT GTGATGATAA AACGAGAATG TTTGGAAATG 
GCAAATTTGA CAGAATGTCA GGGGAACAAT AAGTTTGAAG GATTTTGTAT CGACTTGCTG 
AAACTGTTGG CTGACAAAAT TGAGGAGTTC AATTATGAGA TCAAATTAGG AACAAAGGCG 
GGATCAAAAC AAGCTGACGG AAGCTGGGAT GGAATGATTG GAGAACTTCT GAGTGGAAGA 
GCCCATGCTG TAGTTGCATC ACTTACAATA AATCAAGAAA GAGAACGAGT CGTGGATTTT 
TCAAAACCAT TTATGACAAC TGGAATTTCA ATTATGATCA AGAAGCCTGA CAAACAAGAG 
TTTTCAGTAT TTTCCTTTAT GCAACCGCTT AGTACAGAGA TTTGGATGTA CATCATATTC 
GCGTATATTG GGGTGTCAGT AGTCATCTTT CTTGTTTCAA GGTTTTCACC GTATGAATGG 
AGAGTCGAGG AGACTTCCAG AGGAGGATTC ACTATTTCCA ACGATTTTTC TGTTTATAAT 
TGCTTATGGT TTACACTAGC AGCTTTCATG CAGCAAGGAA CTGATATTTT ACCAAGATCA 
ATTTCGGGTC GTATCGCATC TTCTGCTTGG TGGTTTTTCA CAATGATCAT CGTTTCTTCT 
TACACTGCTA ACTTGGCTGC GTTCCTAACA CTTGAAAAAA TGCAAGCTCC TATAGAAAGT 
GTTGAAGACT TGGCGAAACA GTCGAAGATT AAATACGGAA TTCAAGGTGG CGGATCGACA 
GCTTCTTTCT TCAAATATTC CTCCGTTCAA ATATATCAGA GAATGTGGAG ATATATGGAA 
TCGCAAGTTC CGCCAGTTTT TGTGGCTAGT TATGCGGAAG GAATTGAAAG AGTTCGAAGT 
CATAAAGGAA GATATGCATT TCTTTTAGAA GCAACTGCAA ATGAATATGA GAATACAAGA 
AAACCATGTG ATACAATGAA AGTTGGAGCA AATCTCAACA GTATCGGATA TGGAATAGCG 
ACACCTTTCG GCTCCGACTG GAAGGATCAT ATCAACTTGG CAATTTTAGC CCTCCAAGAA 
CGTGGTGAAC TGAAAAAGTT GGAAAACAAA TGGTGGTATG ATAGAGGACA ATGCGATGCG 
GGTATTACTG TTGACGGGTC ATCTGCTAGT TTGAATCTAT CAAAAGTTGC TGGAATATTT 
TATATTTTAA TGGGTGGTAT GGTCATTTCA ATGTTGGCTG CACTCGGGGA ATTCTTGTAT 
CGAAGTAGGA TTGAAGCGAG GAAATCTAAT TCCAATTCTA TGGTGGCGAA TTTTGCGAAA 
AATTTGAAAA GTGCATTGTC ATCTCAATTA AGATTATCAG TCGAAGGAGG TGCAGTTGCA 
CAACCAGGAT CTCAATCTCA TAATGCAATT AGAAGACAAC AGGTAGCTGC ATTCTTGCCT 
GCAAATGAAA AAGAAGCTTT CAATAATGTG GATCGACCTG CAAACACTCT CTACAACACA 
GCTGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

glr-1 ( NM_066486.7 ) cDNA ORF clone, Caenorhabditis elegans -> NP_498887.2 Caenorhabditis elegans Glutamate receptor 1 (glr-1), mRNA.

Price & Availability↑

CloneID	OCa340849
Clone ID Related Accession (Same CDS sequence)	NM_066486.6 , NM_066486.7
Accession Version	NM_066486.7 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2889bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Caenorhabditis elegans
Product	Glutamate receptor 1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_066486.6.

ATGTTTTCTT CGTTTTCTTT TTTGAACATG TTCGGTGTTC TATTCACTGT TTTCAACTTA 
ACTGTAGTTC AACCATATCC AAGTCATATT ATTATCAAAT CATTTGGGAA CAATGAAGAA 
GTATCGAGAG TGGCTCTGAA AGCTATGGAA TACACATCTG ATCATATCAA TTCCAGAGAC 
GATGTACCGT TTAAACTTGC ATTTGACCAC CGCGTAGTTG AAGAAGGCGC TGCTGTCTCG 
TGGAACATGG TGAACGCAGT CTGTGATGAG CTTAAAGAAG GTGCAATGGC ATTACTTTCA 
AGTGTTGATG GAAAAGGAAG AGAAGGTATT CGAGGAGTAT CTGATGCACT TGAAATGCCT 
CTTGTCTCAC TGACCGCTCT ATCAAATGAT GACCATCAAC AACAACAATT CGGGAATCTT 
TTCGAAGTTT CAGTGAGACC TCCAATTAGT GAACTGCTAG CTGATTTTAT TGTTCACAAA 
GGATGGGGAG AGGTTCTGGT TTTGATTGAC CCAGTACATG CAAGCCTCCA CCTACCATCA 
CTTTGGAGAC ATCTTCGTAC TCGAACCAAT ACTTCTGTCA AAGCGTCCAT GTTCGATTTG 
CCGGCTGATG AAAAACAGTT TGAAGCGTAT TTAATGCAAT TTAATATGAT GAGAAATAAT 
GAAACAAATC GAATACTTAT CGATTGTGCA TCTCCGAAAC GACTCAAGAA ACTTCTAATT 
AATATTCGCT CGGCACAATT TAATCAGGCT AACTATCACT ATGTGCTGGC AAATTATGAT 
TTTCTTCCCT ACGACCAAGA GATGTTCCAA AATGGAAATA TCAATATATC AGGTTTCAAT 
ATAATCAATA AAGATGGAAG AGAGTATTGG TCACTAAAGA AACATTTGAA GACGTCATCT 
TCATTAGGAG GTGGAGATGA TGTTAGTGTT GAGGCAGCTG TTGGACACGA TGCAATGTTA 
GTTACGTGGC ATGGATTTGC AAAGTGCCTG CAAGCGAATG ATTCATTGTT CCATGGTACA 
TTTCGACATA GGAGATTTTT CAATCGTGGA TTTCCAGGAA TCTACTGTGA TCCTCTTTCT 
GACCGTTCTC ATCCAAATCG ACCTTTCTCT TCATTTGAGC ATGGAAAAAC AATCGGAGTT 
GCTTTTAGAA ATATGAAAAT TGGACACAAA GAGGGAACAT TAACTGGGAA TATCGAATTC 
GATCGTTTTG GAAATCGCAA GAACTTTGAT GTATCCATAG TTGACTTGGT ATCAAATACA 
AAAGCAACTT TCAATTCAAA AGAAGTATTA GCGTGGCGAC AAGGTGTTGG ATTCTTCTCA 
AATCGAACAG TTGCTCAACA TTCGAGAAAG AGTCAAAATG ATCATAAGGA TAATCAAGTG 
ATAGTGCTCA CGAATCTAGT TGCTCCATTT GTGATGATAA AACGAGAATG TTTGGAAATG 
GCAAATTTGA CAGAATGTCA GGGGAACAAT AAGTTTGAAG GATTTTGTAT CGACTTGCTG 
AAACTGTTGG CTGACAAAAT TGAGGAGTTC AATTATGAGA TCAAATTAGG AACAAAGGCG 
GGATCAAAAC AAGCTGACGG AAGCTGGGAT GGAATGATTG GAGAACTTCT GAGTGGAAGA 
GCCCATGCTG TAGTTGCATC ACTTACAATA AATCAAGAAA GAGAACGAGT CGTGGATTTT 
TCAAAACCAT TTATGACAAC TGGAATTTCA ATTATGATCA AGAAGCCTGA CAAACAAGAG 
TTTTCAGTAT TTTCCTTTAT GCAACCGCTT AGTACAGAGA TTTGGATGTA CATCATATTC 
GCGTATATTG GGGTGTCAGT AGTCATCTTT CTTGTTTCAA GGTTTTCACC GTATGAATGG 
AGAGTCGAGG AGACTTCCAG AGGAGGATTC ACTATTTCCA ACGATTTTTC TGTTTATAAT 
TGCTTATGGT TTACACTAGC AGCTTTCATG CAGCAAGGAA CTGATATTTT ACCAAGATCA 
ATTTCGGGTC GTATCGCATC TTCTGCTTGG TGGTTTTTCA CAATGATCAT CGTTTCTTCT 
TACACTGCTA ACTTGGCTGC GTTCCTAACA CTTGAAAAAA TGCAAGCTCC TATAGAAAGT 
GTTGAAGACT TGGCGAAACA GTCGAAGATT AAATACGGAA TTCAAGGTGG CGGATCGACA 
GCTTCTTTCT TCAAATATTC CTCCGTTCAA ATATATCAGA GAATGTGGAG ATATATGGAA 
TCGCAAGTTC CGCCAGTTTT TGTGGCTAGT TATGCGGAAG GAATTGAAAG AGTTCGAAGT 
CATAAAGGAA GATATGCATT TCTTTTAGAA GCAACTGCAA ATGAATATGA GAATACAAGA 
AAACCATGTG ATACAATGAA AGTTGGAGCA AATCTCAACA GTATCGGATA TGGAATAGCG 
ACACCTTTCG GCTCCGACTG GAAGGATCAT ATCAACTTGG CAATTTTAGC CCTCCAAGAA 
CGTGGTGAAC TGAAAAAGTT GGAAAACAAA TGGTGGTATG ATAGAGGACA ATGCGATGCG 
GGTATTACTG TTGACGGGTC ATCTGCTAGT TTGAATCTAT CAAAAGTTGC TGGAATATTT 
TATATTTTAA TGGGTGGTAT GGTCATTTCA ATGTTGGCTG CACTCGGGGA ATTCTTGTAT 
CGAAGTAGGA TTGAAGCGAG GAAATCTAAT TCCAATTCTA TGGTGGCGAA TTTTGCGAAA 
AATTTGAAAA GTGCATTGTC ATCTCAATTA AGATTATCAG TCGAAGGAGG TGCAGTTGCA 
CAACCAGGAT CTCAATCTCA TAATGCAATT AGAAGACAAC AGGTAGCTGC ATTCTTGCCT 
GCAAATGAAA AAGAAGCTTT CAATAATGTG GATCGACCTG CAAACACTCT CTACAACACA 
GCTGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_498887.2
CDS	28..2916
Translation	MFSSFSFLNMFGVLFTVFNLTVVQPYPSHIIIKSFGNNEEVSRVALKAMEYTSDHINSRDDVPFKLAFDHRVVEEGAAVSWNMVNAVCDELKEGAMALLSSVDGKGREGIRGVSDALEMPLVSLTALSNDDHQQQQFGNLFEVSVRPPISELLADFIVHKGWGEVLVLIDPVHASLHLPSLWRHLRTRTNTSVKASMFDLPADEKQFEAYLMQFNMMRNNETNRILIDCASPKRLKKLLINIRSAQFNQANYHYVLANYDFLPYDQEMFQNGNINISGFNIINKDGREYWSLKKHLKTSSSLGGGDDVSVEAAVGHDAMLVTWHGFAKCLQANDSLFHGTFRHRRFFNRGFPGIYCDPLSDRSHPNRPFSSFEHGKTIGVAFRNMKIGHKEGTLTGNIEFDRFGNRKNFDVSIVDLVSNTKATFNSKEVLAWRQGVGFFSNRTVAQHSRKSQNDHKDNQVIVLTNLVAPFVMIKRECLEMANLTECQGNNKFEGFCIDLLKLLADKIEEFNYEIKLGTKAGSKQADGSWDGMIGELLSGRAHAVVASLTINQERERVVDFSKPFMTTGISIMIKKPDKQEFSVFSFMQPLSTEIWMYIIFAYIGVSVVIFLVSRFSPYEWRVEETSRGGFTISNDFSVYNCLWFTLAAFMQQGTDILPRSISGRIASSAWWFFTMIIVSSYTANLAAFLTLEKMQAPIESVEDLAKQSKIKYGIQGGGSTASFFKYSSVQIYQRMWRYMESQVPPVFVASYAEGIERVRSHKGRYAFLLEATANEYENTRKPCDTMKVGANLNSIGYGIATPFGSDWKDHINLAILALQERGELKKLENKWWYDRGQCDAGITVDGSSASLNLSKVAGIFYILMGGMVISMLAALGEFLYRSRIEARKSNSNSMVANFAKNLKSALSSQLRLSVEGGAVAQPGSQSHNAIRRQQVAAFLPANEKEAFNNVDRPANTLYNTAV

Target ORF information:

RefSeq Version	NM_066486.7
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Glutamate receptor 1 (glr-1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_066486.7

ORF Insert Sequence:

ATGTTTTCTT CGTTTTCTTT TTTGAACATG TTCGGTGTTC TATTCACTGT TTTCAACTTA 
ACTGTAGTTC AACCATATCC AAGTCATATT ATTATCAAAT CATTTGGGAA CAATGAAGAA 
GTATCGAGAG TGGCTCTGAA AGCTATGGAA TACACATCTG ATCATATCAA TTCCAGAGAC 
GATGTACCGT TTAAACTTGC ATTTGACCAC CGCGTAGTTG AAGAAGGCGC TGCTGTCTCG 
TGGAACATGG TGAACGCAGT CTGTGATGAG CTTAAAGAAG GTGCAATGGC ATTACTTTCA 
AGTGTTGATG GAAAAGGAAG AGAAGGTATT CGAGGAGTAT CTGATGCACT TGAAATGCCT 
CTTGTCTCAC TGACCGCTCT ATCAAATGAT GACCATCAAC AACAACAATT CGGGAATCTT 
TTCGAAGTTT CAGTGAGACC TCCAATTAGT GAACTGCTAG CTGATTTTAT TGTTCACAAA 
GGATGGGGAG AGGTTCTGGT TTTGATTGAC CCAGTACATG CAAGCCTCCA CCTACCATCA 
CTTTGGAGAC ATCTTCGTAC TCGAACCAAT ACTTCTGTCA AAGCGTCCAT GTTCGATTTG 
CCGGCTGATG AAAAACAGTT TGAAGCGTAT TTAATGCAAT TTAATATGAT GAGAAATAAT 
GAAACAAATC GAATACTTAT CGATTGTGCA TCTCCGAAAC GACTCAAGAA ACTTCTAATT 
AATATTCGCT CGGCACAATT TAATCAGGCT AACTATCACT ATGTGCTGGC AAATTATGAT 
TTTCTTCCCT ACGACCAAGA GATGTTCCAA AATGGAAATA TCAATATATC AGGTTTCAAT 
ATAATCAATA AAGATGGAAG AGAGTATTGG TCACTAAAGA AACATTTGAA GACGTCATCT 
TCATTAGGAG GTGGAGATGA TGTTAGTGTT GAGGCAGCTG TTGGACACGA TGCAATGTTA 
GTTACGTGGC ATGGATTTGC AAAGTGCCTG CAAGCGAATG ATTCATTGTT CCATGGTACA 
TTTCGACATA GGAGATTTTT CAATCGTGGA TTTCCAGGAA TCTACTGTGA TCCTCTTTCT 
GACCGTTCTC ATCCAAATCG ACCTTTCTCT TCATTTGAGC ATGGAAAAAC AATCGGAGTT 
GCTTTTAGAA ATATGAAAAT TGGACACAAA GAGGGAACAT TAACTGGGAA TATCGAATTC 
GATCGTTTTG GAAATCGCAA GAACTTTGAT GTATCCATAG TTGACTTGGT ATCAAATACA 
AAAGCAACTT TCAATTCAAA AGAAGTATTA GCGTGGCGAC AAGGTGTTGG ATTCTTCTCA 
AATCGAACAG TTGCTCAACA TTCGAGAAAG AGTCAAAATG ATCATAAGGA TAATCAAGTG 
ATAGTGCTCA CGAATCTAGT TGCTCCATTT GTGATGATAA AACGAGAATG TTTGGAAATG 
GCAAATTTGA CAGAATGTCA GGGGAACAAT AAGTTTGAAG GATTTTGTAT CGACTTGCTG 
AAACTGTTGG CTGACAAAAT TGAGGAGTTC AATTATGAGA TCAAATTAGG AACAAAGGCG 
GGATCAAAAC AAGCTGACGG AAGCTGGGAT GGAATGATTG GAGAACTTCT GAGTGGAAGA 
GCCCATGCTG TAGTTGCATC ACTTACAATA AATCAAGAAA GAGAACGAGT CGTGGATTTT 
TCAAAACCAT TTATGACAAC TGGAATTTCA ATTATGATCA AGAAGCCTGA CAAACAAGAG 
TTTTCAGTAT TTTCCTTTAT GCAACCGCTT AGTACAGAGA TTTGGATGTA CATCATATTC 
GCGTATATTG GGGTGTCAGT AGTCATCTTT CTTGTTTCAA GGTTTTCACC GTATGAATGG 
AGAGTCGAGG AGACTTCCAG AGGAGGATTC ACTATTTCCA ACGATTTTTC TGTTTATAAT 
TGCTTATGGT TTACACTAGC AGCTTTCATG CAGCAAGGAA CTGATATTTT ACCAAGATCA 
ATTTCGGGTC GTATCGCATC TTCTGCTTGG TGGTTTTTCA CAATGATCAT CGTTTCTTCT 
TACACTGCTA ACTTGGCTGC GTTCCTAACA CTTGAAAAAA TGCAAGCTCC TATAGAAAGT 
GTTGAAGACT TGGCGAAACA GTCGAAGATT AAATACGGAA TTCAAGGTGG CGGATCGACA 
GCTTCTTTCT TCAAATATTC CTCCGTTCAA ATATATCAGA GAATGTGGAG ATATATGGAA 
TCGCAAGTTC CGCCAGTTTT TGTGGCTAGT TATGCGGAAG GAATTGAAAG AGTTCGAAGT 
CATAAAGGAA GATATGCATT TCTTTTAGAA GCAACTGCAA ATGAATATGA GAATACAAGA 
AAACCATGTG ATACAATGAA AGTTGGAGCA AATCTCAACA GTATCGGATA TGGAATAGCG 
ACACCTTTCG GCTCCGACTG GAAGGATCAT ATCAACTTGG CAATTTTAGC CCTCCAAGAA 
CGTGGTGAAC TGAAAAAGTT GGAAAACAAA TGGTGGTATG ATAGAGGACA ATGCGATGCG 
GGTATTACTG TTGACGGGTC ATCTGCTAGT TTGAATCTAT CAAAAGTTGC TGGAATATTT 
TATATTTTAA TGGGTGGTAT GGTCATTTCA ATGTTGGCTG CACTCGGGGA ATTCTTGTAT 
CGAAGTAGGA TTGAAGCGAG GAAATCTAAT TCCAATTCTA TGGTGGCGAA TTTTGCGAAA 
AATTTGAAAA GTGCATTGTC ATCTCAATTA AGATTATCAG TCGAAGGAGG TGCAGTTGCA 
CAACCAGGAT CTCAATCTCA TAATGCAATT AGAAGACAAC AGGTAGCTGC ATTCTTGCCT 
GCAAATGAAA AAGAAGCTTT CAATAATGTG GATCGACCTG CAAACACTCT CTACAACACA 
GCTGTCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

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glr-1 cDNA ORF clone, Caenorhabditis elegans

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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