Gene Symbol | tdo-2 |
Entrez Gene ID | 175836 |
Full Name | Tryptophan 2,3-dioxygenase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » tdo-2 cDNA ORF clone
Gene Symbol | tdo-2 |
Entrez Gene ID | 175836 |
Full Name | Tryptophan 2,3-dioxygenase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_065883.4 | NP_498284.1 | Tryptophan 2,3-dioxygenase |
NM_001047382.4 | NP_001040847.1 | Tryptophan 2,3-dioxygenase |
NM_001047382.5 | NP_001040847.1 | Tryptophan 2,3-dioxygenase |
NM_065883.5 | NP_498284.1 | Tryptophan 2,3-dioxygenase |
Pan troglodytes (chimpanzee) | TDO2 | XP_001140187.1 |
Rattus norvegicus (Norway rat) | Tdo2 | NP_071798.1 |
Bos taurus (cattle) | TDO2 | NP_001039778.1 |
Mus musculus (house mouse) | Tdo2 | NP_064295.2 |
Danio rerio (zebrafish) | tdo2b | NP_956150.1 |
Danio rerio (zebrafish) | tdo2a | NP_001096086.1 |
Caenorhabditis elegans (roundworm) | C28H8.11 | NP_498284.1 |
Xenopus tropicalis (tropical clawed frog) | tdo2 | NP_001015733.1 |
Gallus gallus (chicken) | TDO2 | XP_420377.3 |
Drosophila melanogaster (fruit fly) | v | NP_511113.1 |
Canis lupus familiaris (dog) | TDO2 | XP_532700.2 |
Anopheles gambiae (African malaria mosquito) | T23O_ANOGA | XP_312204.2 |
Homo sapiens (human) | TDO2 | NP_005642.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We identify tryptophan 2,3-dioxygenase (tdo-2), the first enzyme in the kynurenine pathway of tryptophan degradation, as a metabolic regulator of age-related alpha-synuclein toxicity.
Title: Delaying aging and the aging-associated decline in protein homeostasis by inhibition of tryptophan degradation.
The following tdo-2 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the tdo-2 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341154 | |
Clone ID Related Accession (Same CDS sequence) | NM_065883.4 , NM_065883.5 | |
Accession Version | NM_065883.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Tryptophan 2,3-dioxygenase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_065883.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGCGTGTC CGTATTTGGG TTCTGGTGAG CTCACGCATA GAGTCACATT TATGGAAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498284.1 |
CDS | 1..1212 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065883.4 |
1 | ATGGCGTGTC CGTATTTGGG TTCTGGTGAG CTCACGCATA GAGTCACATT TATGGAAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341154 | |
Clone ID Related Accession (Same CDS sequence) | NM_065883.4 , NM_065883.5 | |
Accession Version | NM_065883.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1212bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Tryptophan 2,3-dioxygenase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_065883.4. |
1 | ATGGCGTGTC CGTATTTGGG TTCTGGTGAG CTCACGCATA GAGTCACATT TATGGAAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_498284.1 |
CDS | 5..1216 |
Translation |
Target ORF information:
Target ORF information:
|
NM_065883.5 |
1 | ATGGCGTGTC CGTATTTGGG TTCTGGTGAG CTCACGCATA GAGTCACATT TATGGAAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341155 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047382.4 , NM_001047382.5 | |
Accession Version | NM_001047382.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 339bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Tryptophan 2,3-dioxygenase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_001047382.3. COMPLETENESS: incomplete on both ends. |
1 | ATGATGATCT ACTTCTACCG TGACATGCCA CGTTTCTCAC AGCCATATCA GATCCTTACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040847.1 |
CDS | 1..339 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047382.4 |
1 | ATGATGATCT ACTTCTACCG TGACATGCCA CGTTTCTCAC AGCCATATCA GATCCTTACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341155 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047382.4 , NM_001047382.5 | |
Accession Version | NM_001047382.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 339bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Tryptophan 2,3-dioxygenase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_001047382.4. |
1 | ATGATGATCT ACTTCTACCG TGACATGCCA CGTTTCTCAC AGCCATATCA GATCCTTACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040847.1 |
CDS | 4..342 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047382.5 |
1 | ATGATGATCT ACTTCTACCG TGACATGCCA CGTTTCTCAC AGCCATATCA GATCCTTACA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |