Gene Symbol | daf-7 |
Entrez Gene ID | 175237 |
Full Name | Dauer larva development regulatory growth factor daf-7 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » daf-7 cDNA ORF clone
Gene Symbol | daf-7 |
Entrez Gene ID | 175237 |
Full Name | Dauer larva development regulatory growth factor daf-7 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_064864.4 | NP_497265.1 | Dauer larva development regulatory growth factor daf-7 |
NM_064864.5 | NP_497265.1 | Dauer larva development regulatory growth factor daf-7 |
Mus musculus (house mouse) | Gdf11 | NP_034402.1 |
Rattus norvegicus (Norway rat) | Gdf11 | NP_058899.1 |
Pan troglodytes (chimpanzee) | GDF11 | XP_509122.3 |
Homo sapiens (human) | GDF11 | NP_005802.1 |
Danio rerio (zebrafish) | gdf11 | NP_998140.1 |
Caenorhabditis elegans (roundworm) | daf-7 | NP_497265.1 |
Bos taurus (cattle) | GDF11 | XP_002687467.1 |
Xenopus tropicalis (tropical clawed frog) | gdf11 | XP_002934559.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP005289 | XP_309077.3 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The authors show that the interactions between daf-7 and tph-1 regulate redundancy and synergy among neurons in food encoding through coordinated control of circuit-level signal and noise properties.
Title: Genetic control of encoding strategy in a food-sensing neural circuit.
DAF-7 expression decreases as animals age during adulthood. Age-dependent diminished expression contributes to the reduced sensitivity of aging animals to the effects of dietary restriction.
Title: Age-Dependent Neuroendocrine Signaling from Sensory Neurons Modulates the Effect of Dietary Restriction on Longevity of Caenorhabditis elegans.
Using functional, fluorescently-tagged protein, we find that, in animals with mutant DAF-28/IGF, the wild-type DAF-7/TGF-beta is mislocalized to and accumulates in the proximal axon of the ASI neuron. Activation of two different branches of the unfolded protein response can modulate both the developmental phenotype and DAF-7 mislocalization in DAF-28(R37C) animals, but appear to act through divergent mechanisms
Title: A Bystander Mechanism Explains the Specific Phenotype of a Broadly Expressed Misfolded Protein.
blmp-1 is necessary for controlling histone methylation level in daf-7 mutants, suggesting BLMP-1 regulates the expression of SAMS-1, which in turn may regulate histone methylation and dauer formation.Our results reveal a new interaction between BLMP-1/BLIMP-1 and LIN-40/MTA1, as well as potential epigenetic downstream pathways
Title: BLIMP-1/BLMP-1 and Metastasis-Associated Protein Regulate Stress Resistant Development in Caenorhabditis elegans.
GLR-1 protein and glr-1 transcription are increased in neurons of DAF-7 mutants.
Title: The DAF-7/TGF-? signaling pathway regulates abundance of the Caenorhabditis elegans glutamate receptor GLR-1.
The following daf-7 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the daf-7 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa340776 | |
Clone ID Related Accession (Same CDS sequence) | NM_064864.4 , NM_064864.5 | |
Accession Version | NM_064864.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Dauer larva development regulatory growth factor daf-7 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_064864.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTTCATGG CATCTTCACT CCCGGTGTTT ATCTTCCTTC TTTCCCTCCC ACATGGTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_497265.1 |
CDS | 1..1053 |
Translation |
Target ORF information:
Target ORF information:
|
NM_064864.4 |
1 | ATGTTCATGG CATCTTCACT CCCGGTGTTT ATCTTCCTTC TTTCCCTCCC ACATGGTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa340776 | |
Clone ID Related Accession (Same CDS sequence) | NM_064864.4 , NM_064864.5 | |
Accession Version | NM_064864.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1053bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Dauer larva development regulatory growth factor daf-7 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_064864.4. |
1 | ATGTTCATGG CATCTTCACT CCCGGTGTTT ATCTTCCTTC TTTCCCTCCC ACATGGTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_497265.1 |
CDS | 111..1163 |
Translation |
Target ORF information:
Target ORF information:
|
NM_064864.5 |
1 | ATGTTCATGG CATCTTCACT CCCGGTGTTT ATCTTCCTTC TTTCCCTCCC ACATGGTTTG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |