Gene Symbol | pat-4 |
Entrez Gene ID | 175175 |
Full Name | Integrin-linked protein kinase homolog pat-4 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » pat-4 cDNA ORF clone
Gene Symbol | pat-4 |
Entrez Gene ID | 175175 |
Full Name | Integrin-linked protein kinase homolog pat-4 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_064738.6 | NP_497139.1 | Integrin-linked protein kinase homolog pat-4 |
NM_064738.5 | NP_497139.1 | Integrin-linked protein kinase homolog pat-4 |
Canis lupus familiaris (dog) | ILK | XP_534040.1 |
Rattus norvegicus (Norway rat) | Ilk | NP_596900.1 |
ILK | XP_001109041.1 | |
Gallus gallus (chicken) | ILK | NP_989525.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP006573 | XP_316598.2 |
Pan troglodytes (chimpanzee) | ILK | XP_003312944.1 |
Mus musculus (house mouse) | Ilk | NP_001155196.1 |
Xenopus tropicalis (tropical clawed frog) | ilk | NP_001120512.1 |
Danio rerio (zebrafish) | ilk | NP_956865.1 |
Homo sapiens (human) | ILK | NP_004508.1 |
Bos taurus (cattle) | ILK | NP_001029865.1 |
Drosophila melanogaster (fruit fly) | Ilk | NP_525001.2 |
Caenorhabditis elegans (roundworm) | pat-4 | NP_497139.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
isolation and characterization of PAT-4 missense mutations that permit binding with UNC-112 D382V
Title: Suppressor mutations suggest a surface on PAT-4 (Integrin-linked Kinase) that interacts with UNC-112 (Kindlin).
The following model is proposed. UNC-112 exists in closed inactive and open active conformations, and upon binding of PAT-4 to the UNC-112 N-terminal half, UNC-112 is converted into the open state, able to bind to PAT-3.
Title: A molecular mechanism for the requirement of PAT-4 (integrin-linked kinase (ILK)) for the localization of UNC-112 (Kindlin) to integrin adhesion sites.
RNAi of pat-4 inhibited the overall assembly of actin cytoskeleton in somatic gonad, resulting in oocyte accumulation in the proximal gonad and distal tip cells migration defects.
Title: pat-4/ILK and unc-112/Mig-2 are required for gonad function in Caenorhabditis elegans.
The following pat-4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the pat-4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa341187 | |
Clone ID Related Accession (Same CDS sequence) | NM_064738.6 , NM_064738.5 | |
Accession Version | NM_064738.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Integrin-linked protein kinase homolog pat-4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Sep 4, 2019 this sequence version replaced NM_064738.5. |
1 | ATGTCTTTGT CGACTCATTA CCATGCGCAC AAGCCAAATG TGCCCATTAT AATGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_497139.1 |
CDS | 7..1407 |
Translation |
Target ORF information:
Target ORF information:
|
NM_064738.6 |
1 | ATGTCTTTGT CGACTCATTA CCATGCGCAC AAGCCAAATG TGCCCATTAT AATGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa341187 | |
Clone ID Related Accession (Same CDS sequence) | NM_064738.6 , NM_064738.5 | |
Accession Version | NM_064738.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1401bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Integrin-linked protein kinase homolog pat-4 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003281). On Jun 26, 2012 this sequence version replaced NM_064738.4. COMPLETENESS: incomplete on both ends. |
1 | ATGTCTTTGT CGACTCATTA CCATGCGCAC AAGCCAAATG TGCCCATTAT AATGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_497139.1 |
CDS | 1..1401 |
Translation |
Target ORF information:
Target ORF information:
|
NM_064738.5 |
1 | ATGTCTTTGT CGACTCATTA CCATGCGCAC AAGCCAAATG TGCCCATTAT AATGGAGGAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |