Gene Symbol | let-23 |
Entrez Gene ID | 174462 |
Full Name | Receptor protein-tyrosine kinase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » let-23 cDNA ORF clone
Gene Symbol | let-23 |
Entrez Gene ID | 174462 |
Full Name | Receptor protein-tyrosine kinase |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001136359.2 | NP_001129831.1 | Receptor protein-tyrosine kinase |
NM_001136359.3 | NP_001129831.1 | Receptor protein-tyrosine kinase |
NM_001313678.2 | NP_001300607.1 | Receptor protein-tyrosine kinase |
NM_001313678.1 | NP_001300607.1 | Receptor protein-tyrosine kinase |
NM_063561.4 | NP_495962.2 | Receptor tyrosine-protein kinase let-23 |
NM_001136358.2 | NP_001129830.1 | Receptor protein-tyrosine kinase |
NM_063561.5 | NP_495962.2 | Receptor tyrosine-protein kinase let-23 |
NM_001136358.3 | NP_001129830.1 | Receptor protein-tyrosine kinase |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 basolateral localization and signaling during C. elegans vulva induction.
Title: An AGEF-1/Arf GTPase/AP-1 ensemble antagonizes LET-23 EGFR basolateral localization and signaling during C. elegans vulva induction.
ERM-1 prevents the immediate activation of the entire pool of LET-23 EGFR and permits the generation of a long-lasting inductive signal
Title: An in vivo EGF receptor localization screen in C. elegans Identifies the Ezrin homolog ERM-1 as a temporal regulator of signaling.
Rab7, by mediating EGFR trafficking and degradation, plays an important role in downregulation of EGFR signaling
Title: RAB-7 antagonizes LET-23 EGFR signaling during vulva development in Caenorhabditis elegans.
Data show that CDT-2 and CUL-4, members of the CUL-4/DDB-1/CDT-2 E3 ubiquitin ligase complex attenuate LET-23 signalling in vulval precursor cells.
Title: The Caenorhabditis elegans CDT-2 ubiquitin ligase is required for attenuation of EGFR signalling in vulva precursor cells.
Results identify EGF receptor(EGFR) Let-23 substrate protein-8 (EPS-8) as a novel component of the EGFR localization complex that links receptor trafficking to cell fate specification.
Title: Cell fate-specific regulation of EGF receptor trafficking during Caenorhabditis elegans vulval development.
The following let-23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the let-23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa337579 | |
Clone ID Related Accession (Same CDS sequence) | NM_063561.4 , NM_063561.5 | |
Accession Version | NM_063561.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3972bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Receptor tyrosine-protein kinase let-23 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_063561.3. COMPLETENESS: incomplete on both ends. |
1 | ATGCGATACC CTCCCTCTAT CGGTTCAATT TTATTGATTA TTCCTATTTT TCTAACATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495962.2 |
CDS | 1..3972 |
Translation |
Target ORF information:
Target ORF information:
|
NM_063561.4 |
1 | ATGCGATACC CTCCCTCTAT CGGTTCAATT TTATTGATTA TTCCTATTTT TCTAACATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338147 | |
Clone ID Related Accession (Same CDS sequence) | NM_001136358.2 , NM_001136358.3 | |
Accession Version | NM_001136358.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3789bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Receptor protein-tyrosine kinase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_001136358.1. COMPLETENESS: incomplete on both ends. |
1 | ATGTACCGAG GGTGTCGTCG TGTTTATGGA AATCTTGAAA TAACATGGAT AGAAGCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001129830.1 |
CDS | 1..3789 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001136358.2 |
1 | ATGTACCGAG GGTGTCGTCG TGTTTATGGA AATCTTGAAA TAACATGGAT AGAAGCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337579 | |
Clone ID Related Accession (Same CDS sequence) | NM_063561.4 , NM_063561.5 | |
Accession Version | NM_063561.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3972bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Receptor tyrosine-protein kinase let-23 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_063561.4. |
1 | ATGCGATACC CTCCCTCTAT CGGTTCAATT TTATTGATTA TTCCTATTTT TCTAACATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_495962.2 |
CDS | 90..4061 |
Translation |
Target ORF information:
Target ORF information:
|
NM_063561.5 |
1 | ATGCGATACC CTCCCTCTAT CGGTTCAATT TTATTGATTA TTCCTATTTT TCTAACATTT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338146 | |
Clone ID Related Accession (Same CDS sequence) | NM_001136359.2 , NM_001136359.3 | |
Accession Version | NM_001136359.2 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3987bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Receptor protein-tyrosine kinase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_001136359.1. COMPLETENESS: incomplete on both ends. |
1 | ATGAAGTTCC CTTTTTTATT CTTATTTTTA ATAATCTTAA TTGATACAAC AATTGATGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001129831.1 |
CDS | 1..3987 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001136359.2 |
1 | ATGAAGTTCC CTTTTTTATT CTTATTTTTA ATAATCTTAA TTGATACAAC AATTGATGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338146 | |
Clone ID Related Accession (Same CDS sequence) | NM_001136359.2 , NM_001136359.3 | |
Accession Version | NM_001136359.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3987bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Receptor protein-tyrosine kinase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_001136359.2. COMPLETENESS: incomplete on the 5' end. |
1 | ATGAAGTTCC CTTTTTTATT CTTATTTTTA ATAATCTTAA TTGATACAAC AATTGATGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001129831.1 |
CDS | 1..3987 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001136359.3 |
1 | ATGAAGTTCC CTTTTTTATT CTTATTTTTA ATAATCTTAA TTGATACAAC AATTGATGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa338147 | |
Clone ID Related Accession (Same CDS sequence) | NM_001136358.2 , NM_001136358.3 | |
Accession Version | NM_001136358.3 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3789bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Receptor protein-tyrosine kinase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_001136358.2. COMPLETENESS: incomplete on the 5' end. |
1 | ATGTACCGAG GGTGTCGTCG TGTTTATGGA AATCTTGAAA TAACATGGAT AGAAGCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001129830.1 |
CDS | 1..3789 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001136358.3 |
1 | ATGTACCGAG GGTGTCGTCG TGTTTATGGA AATCTTGAAA TAACATGGAT AGAAGCAAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339580 | |
Clone ID Related Accession (Same CDS sequence) | NM_001313678.2 , NM_001313678.1 | |
Accession Version | NM_001313678.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4008bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Receptor protein-tyrosine kinase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_001313678.1. |
1 | ATGAAGTTCC CTTTTTTATT CTTATTTTTA ATAATCTTAA TTGATACAAC AATTGATGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300607.1 |
CDS | 3..4010 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001313678.2 |
1 | ATGAAGTTCC CTTTTTTATT CTTATTTTTA ATAATCTTAA TTGATACAAC AATTGATGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339580 | |
Clone ID Related Accession (Same CDS sequence) | NM_001313678.2 , NM_001313678.1 | |
Accession Version | NM_001313678.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 4008bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Receptor protein-tyrosine kinase | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). COMPLETENESS: incomplete on both ends. |
1 | ATGAAGTTCC CTTTTTTATT CTTATTTTTA ATAATCTTAA TTGATACAAC AATTGATGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001300607.1 |
CDS | 1..4008 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001313678.1 |
1 | ATGAAGTTCC CTTTTTTATT CTTATTTTTA ATAATCTTAA TTGATACAAC AATTGATGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |