Gene Symbol | vab-1 |
Entrez Gene ID | 173794 |
Full Name | Ephrin receptor 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » vab-1 cDNA ORF clone
Gene Symbol | vab-1 |
Entrez Gene ID | 173794 |
Full Name | Ephrin receptor 1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_062406.4 | NP_494807.1 | Ephrin receptor 1 |
NM_062406.3 | NP_494807.1 | Ephrin receptor 1 |
NM_062405.5 | NP_494806.1 | Ephrin receptor 1 |
NM_062405.6 | NP_494806.1 | Ephrin receptor 1 |
Xenopus tropicalis (tropical clawed frog) | epha4 | NP_001135575.1 |
Pan troglodytes (chimpanzee) | EPHA4 | XP_001164828.2 |
EPHA4 | XP_001106493.1 | |
Danio rerio (zebrafish) | epha4a | NP_001005919.1 |
Caenorhabditis elegans (roundworm) | vab-1 | NP_494806.1 |
Canis lupus familiaris (dog) | EPHA4 | XP_005640771.1 |
Mus musculus (house mouse) | Epha4 | NP_031962.2 |
Gallus gallus (chicken) | EPHA4 | NP_990112.1 |
Homo sapiens (human) | EPHA4 | NP_004429.1 |
Rattus norvegicus (Norway rat) | Epha4 | NP_001155883.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
we find that vab-1 lies in the same genetic pathway as cdc-42 and is responsible for polarizing CDC-42 activity to the medial tip. Together, these data establish a previously uncharacterized role for polarized CDC-42, in conjunction with PAR-6, PAR-3 and an Eph receptor(vab-1), during epithelial intercalation.
Title: CDC-42 Orients Cell Migration during Epithelial Intercalation in the Caenorhabditis elegans Epidermis.
Overall locomotion speed increased with increasing nicotine concentration in all tested mutant strains except in the vab-1 mutants
Title: C. elegans and mutants with chronic nicotine exposure as a novel model of cancer phenotype.
Analysis of EFN-1(VAB2) expression and tissue-specific requirements is consistent with a model in which VAB-1 acts in amphid neurons, interacting with EFN-1 expressed on surrounding cells.
Title: Mechanisms of ephrin receptor protein kinase-independent signaling in amphid axon guidance in Caenorhabditis elegans.
The germline apoptosis function of VAB-1 impacts specific cell death pathways, and may act in parallel to extracellular signal-regulated kinase MAPK signaling.
Title: Somatic gonad sheath cells and Eph receptor signaling promote germ-cell death in C. elegans.
VAB-1/Eph RTK can stop axonal outgrowth by inhibiting filopodia formation at the growth cone by activating Arp2/3 through a VAB-1/NCK-1/WSP-1 complex and by inhibiting UNC-34/Ena activity
Title: The Caenorhabditis elegans Eph receptor activates NCK and N-WASP, and inhibits Ena/VASP to regulate growth cone dynamics during axon guidance.
The following vab-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the vab-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa339207 | |
Clone ID Related Accession (Same CDS sequence) | NM_062406.4 , NM_062406.3 | |
Accession Version | NM_062406.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3354bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Ephrin receptor 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_062406.3. |
1 | ATGCGGTTGT ACAATTCGCG GATTCTAAAT CCCCACCAAT CGATATTTAT TCTGGTTCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_494807.1 |
CDS | 90..3443 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062406.4 |
1 | ATGCGGTTGT ACAATTCGCG GATTCTAAAT CCCCACCAAT CGATATTTAT TCTGGTTCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339207 | |
Clone ID Related Accession (Same CDS sequence) | NM_062406.4 , NM_062406.3 | |
Accession Version | NM_062406.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3354bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Ephrin receptor 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_062406.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCGGTTGT ACAATTCGCG GATTCTAAAT CCCCACCAAT CGATATTTAT TCTGGTTCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_494807.1 |
CDS | 1..3354 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062406.3 |
1 | ATGCGGTTGT ACAATTCGCG GATTCTAAAT CCCCACCAAT CGATATTTAT TCTGGTTCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339208 | |
Clone ID Related Accession (Same CDS sequence) | NM_062405.5 , NM_062405.6 | |
Accession Version | NM_062405.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3369bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Ephrin receptor 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_062405.4. COMPLETENESS: incomplete on both ends. |
1 | ATGCGGTTGT ACAATTCGCG GATTCTAAAT CCCCACCAAT CGATATTTAT TCTGGTTCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_494806.1 |
CDS | 1..3369 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062405.5 |
1 | ATGCGGTTGT ACAATTCGCG GATTCTAAAT CCCCACCAAT CGATATTTAT TCTGGTTCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa339208 | |
Clone ID Related Accession (Same CDS sequence) | NM_062405.5 , NM_062405.6 | |
Accession Version | NM_062405.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 3369bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Ephrin receptor 1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_062405.5. |
1 | ATGCGGTTGT ACAATTCGCG GATTCTAAAT CCCCACCAAT CGATATTTAT TCTGGTTCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_494806.1 |
CDS | 90..3458 |
Translation |
Target ORF information:
Target ORF information:
|
NM_062405.6 |
1 | ATGCGGTTGT ACAATTCGCG GATTCTAAAT CCCCACCAAT CGATATTTAT TCTGGTTCTA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |