cwn-1 cDNA ORF clone, Caenorhabditis elegans

Gene
Clones
gRNAs

Summary

Gene Symbol	cwn-1
Entrez Gene ID	173399
Full Name	Protein Wnt-1
Gene Type	protein-coding
Organism	Caenorhabditis elegans

mRNA and Protein(s)

mRNA	Protein	Name
NM_061267.4	NP_493668.1	Protein Wnt-1
NM_061267.5	NP_493668.1	Protein Wnt-1

Pathways from BioSystems

Homologies

Mus musculus (house mouse)	Wnt4	NP_033549.1
Drosophila melanogaster (fruit fly)	Wnt5	NP_476924.1
Caenorhabditis elegans (roundworm)	cwn-1	NP_493668.1
Xenopus tropicalis (tropical clawed frog)	wnt4	NP_001239015.1
Homo sapiens (human)	WNT4	NP_110388.2
Pan troglodytes (chimpanzee)	WNT4	XP_524597.3
Bos taurus (cattle)	WNT4	XP_003585839.2
Rattus norvegicus (Norway rat)	Wnt4	NP_445854.1
Canis lupus familiaris (dog)	WNT4	XP_855190.3
Gallus gallus (chicken)	WNT4	NP_990114.1
Danio rerio (zebrafish)	wnt4a	NP_001035477.1
	WNT4	XP_001100814.1

Gene Ontology
Bibliography

Related articles in PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.

Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

our results strongly suggest that functions of at least four Wnts (lin-44, cwn-1, cwn-2, and egl-20) determine the polarity orientation of seam cells
Title: Multiple Wnts redundantly control polarity orientation in Caenorhabditis elegans epithelial stem cells.

C. elegans Wnt homolog, cwn-1, functions to regulate asymmetric division of the ABpl/rpppa blast cell. Cwn-1 does not act alone in this process, and it functions with another redundant ligand that appears not to be a Wnt.
Title: CWN-1 functions with DSH-2 to regulate C. elegans asymmetric neuroblast division in a beta-catenin independent Wnt pathway.

Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos
Title: Src and Wnt signaling regulate dynactin accumulation to the P2-EMS cell border in C. elegans embryos.

CAM-1 interacts with and inhibits Egl-20, CWN-1 and MOM-2 during vulva morphogenesis.
Title: The C. elegans ROR receptor tyrosine kinase, CAM-1, non-autonomously inhibits the Wnt pathway.

Here, too, we found that four of five Wnt receptors can influence P7.p orientation, suggesting that a surprising amount of functional redundancy exists in Wnt signaling during C. elegans vulval induction.
Title: Multiple redundant Wnt signaling components function in two processes during C. elegans vulval development.

The following cwn-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the cwn-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OCa338959	NM_061267.5 Latest version!	Caenorhabditis elegans Protein Wnt-1 (cwn-1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$223.30 $319.00
View Old Accession Versions >>
OCa338959	NM_061267.4	Caenorhabditis elegans Protein Wnt-1 (cwn-1), partial mRNA.	pcDNA3.1-C-(k)DYK or customized vector	9-11	$258.30 $369.00
Hide Old Accession Versions >>

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

cwn-1 ( NM_061267.4 ) cDNA ORF clone, Caenorhabditis elegans -> NP_493668.1 Caenorhabditis elegans Protein Wnt-1 (cwn-1), partial mRNA.

Price & Availability↑

CloneID	OCa338959
Clone ID Related Accession (Same CDS sequence)	NM_061267.4 , NM_061267.5
Accession Version	NM_061267.4	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-04-08
Organism	Caenorhabditis elegans
Product	Protein Wnt-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Jun 26, 2012 this sequence version replaced NM_061267.3. COMPLETENESS: incomplete on both ends.

ATGCTGAAAT CTACACAAGT GATCCTAATC TTCATTTTAC TGATTTCAAT TGTCGAAAGC 
TTGTCATGGT TAGCACTCGG GCTTGCTGCC AACCGATTTG ACAGAGATAA ACCGGGAACG 
TCATGTAAAT CACTGAAAGG GCTCACCAGG AGGCAGATGA GATTCTGTAA AAAGAACATT 
GACTTAATGG AAAGTGTTCG TTCGGGATCT CTCGCTGCTC ATGCTGAATG CCAATTTCAA 
TTTCATAAAC GCAGATGGAA TTGCACTTTG ATCGATCCGG TGACTCATGA AGTCATCCCG 
GACGTTTTTC TCTATGAAAA CACTAGAGAA TCGGCATTTG TACATGCAAT TTCGTCAGCT 
GCTGTTGCTT ATAAGGTTAC CCGAGATTGT GCTAGAGGAA TAAGTGAACG ATGCGGTTGT 
GACTACTCGA AAAACGATCA CTCAGGGAAA AGTCAATTCC AATATCAGGG CTGCTCGGAC 
AATGTTAAAT TTGGAATTGG TGTCTCCAAA GAGTTTGTTG ATTCCGCTCA ACGGAGAGTT 
TTGATGATGA AGGACGATAA TGGAACAAGT CTTCTGGGAC CTAGCCAGCT GTCTGCCGAT 
GGAATGCATA TGATTAATTT GCATAATAAT CAAGCTGGAA GACAGGTCCT CGAAAAGTCT 
CTTCGTCGAG AATGCAAGTG TCATGGAATG AGTGGATCTT GTGAAATGAG GACTTGTTGG 
GATTCATTAC CAAACTTCAG GCATATCGGA ATGGCAATCA AGGATAAGTT CGATGGAGCT 
GCCGAGGTTA AAGTCGTCAA AGAGGATGGT ATTGAGAAAC CTCGAATCGT GATGAAAAAT 
TCTCAGTTCA AGCGACACAC TAACGCGGAT CTGGTCTACA TGACTCCATC CCCCGACTTT 
TGTGAATCTG ACCCACTACG TGGCATACTC GGAACCAAAG GTCGTCAGTG CACTCTTGCA 
CCGAATGCGA TTGATGACTG CAGTTTGCTC TGTTGTGGTC GTGGATACGA GAAGAAGGTG 
CAAATAGTCG AGGAGAAGTG CAATTGCAAG TTCATCTACT GCTGTGAAGT ACGATGTGAG 
CCATGTCAGA AACGAATTGA GAAGTATTTA TGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_493668.1
CDS	1..1119
Translation	MLKSTQVILIFILLISIVESLSWLALGLAANRFDRDKPGTSCKSLKGLTRRQMRFCKKNIDLMESVRSGSLAAHAECQFQFHKRRWNCTLIDPVTHEVIPDVFLYENTRESAFVHAISSAAVAYKVTRDCARGISERCGCDYSKNDHSGKSQFQYQGCSDNVKFGIGVSKEFVDSAQRRVLMMKDDNGTSLLGPSQLSADGMHMINLHNNQAGRQVLEKSLRRECKCHGMSGSCEMRTCWDSLPNFRHIGMAIKDKFDGAAEVKVVKEDGIEKPRIVMKNSQFKRHTNADLVYMTPSPDFCESDPLRGILGTKGRQCTLAPNAIDDCSLLCCGRGYEKKVQIVEEKCNCKFIYCCEVRCEPCQKRIEKYLCL

Target ORF information:

RefSeq Version	NM_061267.4
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Protein Wnt-1 (cwn-1), partial mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_061267.4

ORF Insert Sequence:

ATGCTGAAAT CTACACAAGT GATCCTAATC TTCATTTTAC TGATTTCAAT TGTCGAAAGC 
TTGTCATGGT TAGCACTCGG GCTTGCTGCC AACCGATTTG ACAGAGATAA ACCGGGAACG 
TCATGTAAAT CACTGAAAGG GCTCACCAGG AGGCAGATGA GATTCTGTAA AAAGAACATT 
GACTTAATGG AAAGTGTTCG TTCGGGATCT CTCGCTGCTC ATGCTGAATG CCAATTTCAA 
TTTCATAAAC GCAGATGGAA TTGCACTTTG ATCGATCCGG TGACTCATGA AGTCATCCCG 
GACGTTTTTC TCTATGAAAA CACTAGAGAA TCGGCATTTG TACATGCAAT TTCGTCAGCT 
GCTGTTGCTT ATAAGGTTAC CCGAGATTGT GCTAGAGGAA TAAGTGAACG ATGCGGTTGT 
GACTACTCGA AAAACGATCA CTCAGGGAAA AGTCAATTCC AATATCAGGG CTGCTCGGAC 
AATGTTAAAT TTGGAATTGG TGTCTCCAAA GAGTTTGTTG ATTCCGCTCA ACGGAGAGTT 
TTGATGATGA AGGACGATAA TGGAACAAGT CTTCTGGGAC CTAGCCAGCT GTCTGCCGAT 
GGAATGCATA TGATTAATTT GCATAATAAT CAAGCTGGAA GACAGGTCCT CGAAAAGTCT 
CTTCGTCGAG AATGCAAGTG TCATGGAATG AGTGGATCTT GTGAAATGAG GACTTGTTGG 
GATTCATTAC CAAACTTCAG GCATATCGGA ATGGCAATCA AGGATAAGTT CGATGGAGCT 
GCCGAGGTTA AAGTCGTCAA AGAGGATGGT ATTGAGAAAC CTCGAATCGT GATGAAAAAT 
TCTCAGTTCA AGCGACACAC TAACGCGGAT CTGGTCTACA TGACTCCATC CCCCGACTTT 
TGTGAATCTG ACCCACTACG TGGCATACTC GGAACCAAAG GTCGTCAGTG CACTCTTGCA 
CCGAATGCGA TTGATGACTG CAGTTTGCTC TGTTGTGGTC GTGGATACGA GAAGAAGGTG 
CAAATAGTCG AGGAGAAGTG CAATTGCAAG TTCATCTACT GCTGTGAAGT ACGATGTGAG 
CCATGTCAGA AACGAATTGA GAAGTATTTA TGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

cwn-1 ( NM_061267.5 ) cDNA ORF clone, Caenorhabditis elegans -> NP_493668.1 Caenorhabditis elegans Protein Wnt-1 (cwn-1), mRNA.

Price & Availability↑

CloneID	OCa338959
Clone ID Related Accession (Same CDS sequence)	NM_061267.4 , NM_061267.5
Accession Version	NM_061267.5 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1119bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Caenorhabditis elegans
Product	Protein Wnt-1
Comment	Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003280). On Sep 4, 2019 this sequence version replaced NM_061267.4.

ATGCTGAAAT CTACACAAGT GATCCTAATC TTCATTTTAC TGATTTCAAT TGTCGAAAGC 
TTGTCATGGT TAGCACTCGG GCTTGCTGCC AACCGATTTG ACAGAGATAA ACCGGGAACG 
TCATGTAAAT CACTGAAAGG GCTCACCAGG AGGCAGATGA GATTCTGTAA AAAGAACATT 
GACTTAATGG AAAGTGTTCG TTCGGGATCT CTCGCTGCTC ATGCTGAATG CCAATTTCAA 
TTTCATAAAC GCAGATGGAA TTGCACTTTG ATCGATCCGG TGACTCATGA AGTCATCCCG 
GACGTTTTTC TCTATGAAAA CACTAGAGAA TCGGCATTTG TACATGCAAT TTCGTCAGCT 
GCTGTTGCTT ATAAGGTTAC CCGAGATTGT GCTAGAGGAA TAAGTGAACG ATGCGGTTGT 
GACTACTCGA AAAACGATCA CTCAGGGAAA AGTCAATTCC AATATCAGGG CTGCTCGGAC 
AATGTTAAAT TTGGAATTGG TGTCTCCAAA GAGTTTGTTG ATTCCGCTCA ACGGAGAGTT 
TTGATGATGA AGGACGATAA TGGAACAAGT CTTCTGGGAC CTAGCCAGCT GTCTGCCGAT 
GGAATGCATA TGATTAATTT GCATAATAAT CAAGCTGGAA GACAGGTCCT CGAAAAGTCT 
CTTCGTCGAG AATGCAAGTG TCATGGAATG AGTGGATCTT GTGAAATGAG GACTTGTTGG 
GATTCATTAC CAAACTTCAG GCATATCGGA ATGGCAATCA AGGATAAGTT CGATGGAGCT 
GCCGAGGTTA AAGTCGTCAA AGAGGATGGT ATTGAGAAAC CTCGAATCGT GATGAAAAAT 
TCTCAGTTCA AGCGACACAC TAACGCGGAT CTGGTCTACA TGACTCCATC CCCCGACTTT 
TGTGAATCTG ACCCACTACG TGGCATACTC GGAACCAAAG GTCGTCAGTG CACTCTTGCA 
CCGAATGCGA TTGATGACTG CAGTTTGCTC TGTTGTGGTC GTGGATACGA GAAGAAGGTG 
CAAATAGTCG AGGAGAAGTG CAATTGCAAG TTCATCTACT GCTGTGAAGT ACGATGTGAG 
CCATGTCAGA AACGAATTGA GAAGTATTTA TGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_493668.1
CDS	22..1140
Translation	MLKSTQVILIFILLISIVESLSWLALGLAANRFDRDKPGTSCKSLKGLTRRQMRFCKKNIDLMESVRSGSLAAHAECQFQFHKRRWNCTLIDPVTHEVIPDVFLYENTRESAFVHAISSAAVAYKVTRDCARGISERCGCDYSKNDHSGKSQFQYQGCSDNVKFGIGVSKEFVDSAQRRVLMMKDDNGTSLLGPSQLSADGMHMINLHNNQAGRQVLEKSLRRECKCHGMSGSCEMRTCWDSLPNFRHIGMAIKDKFDGAAEVKVVKEDGIEKPRIVMKNSQFKRHTNADLVYMTPSPDFCESDPLRGILGTKGRQCTLAPNAIDDCSLLCCGRGYEKKVQIVEEKCNCKFIYCCEVRCEPCQKRIEKYLCL

Target ORF information:

RefSeq Version	NM_061267.5
Organism	Caenorhabditis elegans
Definition	Caenorhabditis elegans Protein Wnt-1 (cwn-1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_061267.5

ORF Insert Sequence:

ATGCTGAAAT CTACACAAGT GATCCTAATC TTCATTTTAC TGATTTCAAT TGTCGAAAGC 
TTGTCATGGT TAGCACTCGG GCTTGCTGCC AACCGATTTG ACAGAGATAA ACCGGGAACG 
TCATGTAAAT CACTGAAAGG GCTCACCAGG AGGCAGATGA GATTCTGTAA AAAGAACATT 
GACTTAATGG AAAGTGTTCG TTCGGGATCT CTCGCTGCTC ATGCTGAATG CCAATTTCAA 
TTTCATAAAC GCAGATGGAA TTGCACTTTG ATCGATCCGG TGACTCATGA AGTCATCCCG 
GACGTTTTTC TCTATGAAAA CACTAGAGAA TCGGCATTTG TACATGCAAT TTCGTCAGCT 
GCTGTTGCTT ATAAGGTTAC CCGAGATTGT GCTAGAGGAA TAAGTGAACG ATGCGGTTGT 
GACTACTCGA AAAACGATCA CTCAGGGAAA AGTCAATTCC AATATCAGGG CTGCTCGGAC 
AATGTTAAAT TTGGAATTGG TGTCTCCAAA GAGTTTGTTG ATTCCGCTCA ACGGAGAGTT 
TTGATGATGA AGGACGATAA TGGAACAAGT CTTCTGGGAC CTAGCCAGCT GTCTGCCGAT 
GGAATGCATA TGATTAATTT GCATAATAAT CAAGCTGGAA GACAGGTCCT CGAAAAGTCT 
CTTCGTCGAG AATGCAAGTG TCATGGAATG AGTGGATCTT GTGAAATGAG GACTTGTTGG 
GATTCATTAC CAAACTTCAG GCATATCGGA ATGGCAATCA AGGATAAGTT CGATGGAGCT 
GCCGAGGTTA AAGTCGTCAA AGAGGATGGT ATTGAGAAAC CTCGAATCGT GATGAAAAAT 
TCTCAGTTCA AGCGACACAC TAACGCGGAT CTGGTCTACA TGACTCCATC CCCCGACTTT 
TGTGAATCTG ACCCACTACG TGGCATACTC GGAACCAAAG GTCGTCAGTG CACTCTTGCA 
CCGAATGCGA TTGATGACTG CAGTTTGCTC TGTTGTGGTC GTGGATACGA GAAGAAGGTG 
CAAATAGTCG AGGAGAAGTG CAATTGCAAG TTCATCTACT GCTGTGAAGT ACGATGTGAG 
CCATGTCAGA AACGAATTGA GAAGTATTTA TGCTTATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)

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cwn-1 cDNA ORF clone, Caenorhabditis elegans

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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