| Gene Symbol | gsk-3 |
| Entrez Gene ID | 173149 |
| Full Name | Glycogen synthase kinase-3 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » gsk-3 cDNA ORF clone
| Gene Symbol | gsk-3 |
| Entrez Gene ID | 173149 |
| Full Name | Glycogen synthase kinase-3 |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_060842.5 | NP_493243.1 | Glycogen synthase kinase-3 |
| NM_060842.6 | NP_493243.1 | Glycogen synthase kinase-3 |
| Bos taurus (cattle) | GSK3B | NP_001094780.1 |
| Mus musculus (house mouse) | Gsk3b | NP_062801.1 |
| Rattus norvegicus (Norway rat) | Gsk3b | NP_114469.1 |
| Caenorhabditis elegans (roundworm) | gsk-3 | NP_493243.1 |
| Xenopus tropicalis (tropical clawed frog) | gsk3b | XP_002941025.2 |
| Pan troglodytes (chimpanzee) | GSK3B | XP_003339094.1 |
| Canis lupus familiaris (dog) | GSK3B | XP_535751.2 |
| Danio rerio (zebrafish) | gsk3b | NP_571456.1 |
| Homo sapiens (human) | GSK3B | NP_002084.2 |
| Arabidopsis thaliana (thale cress) | SK13 | NP_196968.2 |
| Gallus gallus (chicken) | GSK3B | XP_416557.4 |
| Oryza sativa (rice) | Os05g0134000 | NP_001054564.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Rearrangement of mitotic spindles requires the GSK-3 kinase. Apoptotic cell clearance and migration of the distal tip cell require the GSK-3 kinase.
Title: The Wnt pathway controls cell death engulfment, spindle orientation, and migration through CED-10/Rac.
GSK3 converts OMA-1 and OMA-2 from being key regulators of oocyte maturation to key regulators of 1-cell embryo development
Title: DYRK2 and GSK-3 phosphorylate and promote the timely degradation of OMA-1, a key regulator of the oocyte-to-embryo transition in C. elegans.
(i) GSK-3 inhibits SKN-1 activity in the intestine, (ii) the phase II response integrates multiple regulatory signals, and (iii), by inhibiting this response, GSK-3 may influence redox conditions.
Title: Regulation of the Caenorhabditis elegans oxidative stress defense protein SKN-1 by glycogen synthase kinase-3.
The following gsk-3 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the gsk-3 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa336048 | |
| Clone ID Related Accession (Same CDS sequence) | NM_060842.5 , NM_060842.6 | |
| Accession Version | NM_060842.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Glycogen synthase kinase-3 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060842.4. COMPLETENESS: incomplete on both ends. | |
1 | ATGAATAAGC AGTTACTATC GTGCTCGCTG AAAAGCGGAA AACAAGTGAC GATGGTCGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_493243.1 |
| CDS | 1..1089 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_060842.5 |
1 | ATGAATAAGC AGTTACTATC GTGCTCGCTG AAAAGCGGAA AACAAGTGAC GATGGTCGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa336048 | |
| Clone ID Related Accession (Same CDS sequence) | NM_060842.5 , NM_060842.6 | |
| Accession Version | NM_060842.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 1089bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Glycogen synthase kinase-3 | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060842.5. | |
1 | ATGAATAAGC AGTTACTATC GTGCTCGCTG AAAAGCGGAA AACAAGTGAC GATGGTCGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_493243.1 |
| CDS | 147..1235 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_060842.6 |
1 | ATGAATAAGC AGTTACTATC GTGCTCGCTG AAAAGCGGAA AACAAGTGAC GATGGTCGTC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |