Gene Symbol | par-6 |
Entrez Gene ID | 173137 |
Full Name | Partitioning defective protein 6 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » par-6 cDNA ORF clone
Gene Symbol | par-6 |
Entrez Gene ID | 173137 |
Full Name | Partitioning defective protein 6 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_001047222.4 | NP_001040687.1 | Partitioning defective protein 6 |
NM_001047223.3 | NP_001040688.1 | Partitioning defective protein 6 |
NM_001047223.4 | NP_001040688.1 | Partitioning defective protein 6 |
NM_001047222.5 | NP_001040687.1 | Partitioning defective protein 6 |
Pan troglodytes (chimpanzee) | PARD6G | XP_001145392.1 |
Rattus norvegicus (Norway rat) | Pard6g | NP_001094443.1 |
Gallus gallus (chicken) | PARD6G | XP_426065.4 |
Homo sapiens (human) | PARD6G | NP_115899.1 |
Xenopus tropicalis (tropical clawed frog) | pard6g | NP_001017338.1 |
PARD6G | XP_001090088.1 | |
Bos taurus (cattle) | PARD6G | NP_001091569.1 |
Mus musculus (house mouse) | Pard6g | NP_444347.3 |
Drosophila melanogaster (fruit fly) | par-6 | NP_573238.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP010494 | XP_314468.4 |
Canis lupus familiaris (dog) | PARD6G | XP_541043.2 |
Danio rerio (zebrafish) | pard6gb | NP_997728.1 |
Caenorhabditis elegans (roundworm) | par-6 | NP_001040687.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
we find that vab-1 lies in the same genetic pathway as cdc-42 and is responsible for polarizing CDC-42 activity to the medial tip. Together, these data establish a previously uncharacterized role for polarized CDC-42, in conjunction with PAR-6, PAR-3 and an Eph receptor(vab-1), during epithelial intercalation.
Title: CDC-42 Orients Cell Migration during Epithelial Intercalation in the Caenorhabditis elegans Epidermis.
the arcade cell epithelium polarizes by a PAR-6-mediated pathway that is independent of E-cadherin, beta-integrin and beta-laminin.
Title: PAR-6, but not E-cadherin and ?-integrin, is necessary for epithelial polarization in C. elegans.
Our results support a model in which CYB-2.1/2/CDK-1 antagonize CUL-2 activity to promote stabilization of PAR-6 levels during polarization of the early C. elegans embryo.
Title: CDK-1 and two B-type cyclins promote PAR-6 stabilization during polarization of the early C. elegans embryo.
PAR-3 and PAR-6 function in cytokinesis may be partially redundant and play a role in the maintenance of DYN-1 in the cleavage furrow.
Title: Anterior PAR proteins function during cytokinesis and maintain DYN-1 at the cleavage furrow in Caenorhabditis elegans.
Centrosomes localize apically by first moving toward lateral foci of the conserved polarity proteins PAR-3 and PAR-6, then move together with these foci toward the future apical surface. Embryos lacking PAR-3 fail to localize their centrosomes apically.
Title: A role for the centrosome and PAR-3 in the hand-off of MTOC function during epithelial polarization.
The following par-6 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the par-6 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335550 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047222.4 , NM_001047222.5 | |
Accession Version | NM_001047222.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Partitioning defective protein 6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_001047222.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTCCTACA ACGGCTCCTA CCATCAAAAT CATCATTCAA CACTTCAAGT CAAATCGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040687.1 |
CDS | 1..930 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047222.4 |
1 | ATGTCCTACA ACGGCTCCTA CCATCAAAAT CATCATTCAA CACTTCAAGT CAAATCGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335550 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047222.4 , NM_001047222.5 | |
Accession Version | NM_001047222.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 930bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Partitioning defective protein 6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001047222.4. |
1 | ATGTCCTACA ACGGCTCCTA CCATCAAAAT CATCATTCAA CACTTCAAGT CAAATCGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040687.1 |
CDS | 79..1008 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047222.5 |
1 | ATGTCCTACA ACGGCTCCTA CCATCAAAAT CATCATTCAA CACTTCAAGT CAAATCGAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337261 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047223.3 , NM_001047223.4 | |
Accession Version | NM_001047223.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Partitioning defective protein 6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_001047223.2. COMPLETENESS: incomplete on both ends. |
1 | ATGGCACAAA AACCACCGAA ACGCAGTTAT TCAATCTCGA ATCCCGAAGA TTTTCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040688.1 |
CDS | 1..570 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047223.3 |
1 | ATGGCACAAA AACCACCGAA ACGCAGTTAT TCAATCTCGA ATCCCGAAGA TTTTCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337261 | |
Clone ID Related Accession (Same CDS sequence) | NM_001047223.3 , NM_001047223.4 | |
Accession Version | NM_001047223.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 570bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Partitioning defective protein 6 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001047223.3. COMPLETENESS: incomplete on the 5' end. |
1 | ATGGCACAAA AACCACCGAA ACGCAGTTAT TCAATCTCGA ATCCCGAAGA TTTTCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001040688.1 |
CDS | 1..570 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001047223.4 |
1 | ATGGCACAAA AACCACCGAA ACGCAGTTAT TCAATCTCGA ATCCCGAAGA TTTTCGACAG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |