Gene Symbol | kpc-1 |
Entrez Gene ID | 173051 |
Full Name | Furin-like protease kpc-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » kpc-1 cDNA ORF clone
Gene Symbol | kpc-1 |
Entrez Gene ID | 173051 |
Full Name | Furin-like protease kpc-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_060573.5 | NP_492974.2 | Furin-like protease kpc-1 |
NM_060573.6 | NP_492974.2 | Furin-like protease kpc-1 |
Pan troglodytes (chimpanzee) | FURIN | XP_510596.2 |
Rattus norvegicus (Norway rat) | Furin | NP_062204.1 |
Caenorhabditis elegans (roundworm) | kpc-1 | NP_492974.2 |
Mus musculus (house mouse) | Furin | NP_001074923.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP001330 | XP_321814.4 |
Homo sapiens (human) | FURIN | NP_002560.1 |
Canis lupus familiaris (dog) | FURIN | XP_850069.2 |
Bos taurus (cattle) | FURIN | NP_776561.1 |
Danio rerio (zebrafish) | furinb | NP_001038574.2 |
Xenopus tropicalis (tropical clawed frog) | furin | XP_004912697.1 |
FURIN | XP_001094068.1 | |
Gallus gallus (chicken) | FURIN | NP_990046.1 |
Danio rerio (zebrafish) | furina | NP_001038571.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We identify a Chimaerin (CHIN-1)- Furin (KPC-1) double-mutant that severely disrupts assembly. CHIN-1 and KPC-1 function noncanonically, in glia and pioneer neurons, for guidance-cue trafficking.
Title: Glia initiate brain assembly through noncanonical Chimaerin-Furin axon guidance in C. elegans.
The authors show that KPC-1, a Caenorhabditis elegans furin homolog, regulates the level of the branching receptor DMA-1 on dendrites by targeting it to late endosomes.
Title: Precise regulation of the guidance receptor DMA-1 by KPC-1/Furin instructs dendritic branching decisions.
The C. elegans furin homolog KPC-1 is required for dauer IL2 dendritic arborization and dauer-specific nictation behavior. KPC-1 is also necessary for dendritic arborization of PVD and FLP sensory neurons.
Title: Dauer-specific dendrite arborization in C. elegans is regulated by KPC-1/Furin.
The following kpc-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the kpc-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335762 | |
Clone ID Related Accession (Same CDS sequence) | NM_060573.5 , NM_060573.6 | |
Accession Version | NM_060573.5 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2079bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Furin-like protease kpc-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060573.4. COMPLETENESS: incomplete on both ends. |
1 | ATGTCAAATA TCAGTTGGTA CCGTCATTGT TCGGTTCGGC TTCAACTCGT CACACTTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492974.2 |
CDS | 1..2079 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060573.5 |
1 | ATGTCAAATA TCAGTTGGTA CCGTCATTGT TCGGTTCGGC TTCAACTCGT CACACTTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335762 | |
Clone ID Related Accession (Same CDS sequence) | NM_060573.5 , NM_060573.6 | |
Accession Version | NM_060573.6 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 2079bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Furin-like protease kpc-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060573.5. |
1 | ATGTCAAATA TCAGTTGGTA CCGTCATTGT TCGGTTCGGC TTCAACTCGT CACACTTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492974.2 |
CDS | 101..2179 |
Translation |
Target ORF information:
Target ORF information:
|
NM_060573.6 |
1 | ATGTCAAATA TCAGTTGGTA CCGTCATTGT TCGGTTCGGC TTCAACTCGT CACACTTGCA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |