| Gene Symbol | skr-1 |
| Entrez Gene ID | 172775 |
| Full Name | Skp1-related protein |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » skr-1 cDNA ORF clone
| Gene Symbol | skr-1 |
| Entrez Gene ID | 172775 |
| Full Name | Skp1-related protein |
| Gene Type | protein-coding |
| Organism | Caenorhabditis elegans |
| mRNA | Protein | Name |
|---|---|---|
| NM_060112.5 | NP_492513.1 | Skp1-related protein |
| NM_060112.6 | NP_492513.1 | Skp1-related protein |
| Canis lupus familiaris (dog) | SKP1 | NP_001239337.1 |
| Drosophila melanogaster (fruit fly) | skpA | NP_726695.1 |
| Caenorhabditis elegans (roundworm) | skr-1 | NP_492513.1 |
| Kluyveromyces lactis | KLLA0E16941g | XP_454713.1 |
| Eremothecium gossypii | AGOS_ADR295C | NP_984392.1 |
| Schizosaccharomyces pombe (fission yeast) | skp1 | NP_595455.1 |
| Xenopus tropicalis (tropical clawed frog) | skp1 | NP_001016519.1 |
| Gallus gallus (chicken) | SKP1 | NP_001006153.1 |
| Saccharomyces cerevisiae (baker's yeast) | SKP1 | NP_010615.3 |
| Homo sapiens (human) | SKP1 | NP_733779.1 |
| Pan troglodytes (chimpanzee) | SKP1 | XP_003950673.1 |
| Bos taurus (cattle) | SKP1 | NP_001029953.1 |
| Danio rerio (zebrafish) | skp1 | NP_957037.1 |
| Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008719 | XP_314827.2 |
| Caenorhabditis elegans (roundworm) | skr-2 | NP_492512.1 |
| Magnaporthe oryzae (rice blast fungus) | MGG_04978 | XP_003712477.1 |
| Neurospora crassa | NCU08991 | XP_959019.1 |
| LOC703550 | XP_001094634.1 | |
| Mus musculus (house mouse) | Skp1a | NP_035673.3 |
| Rattus norvegicus (Norway rat) | Skp1 | NP_001007609.1 |
| Oryza sativa (rice) | Os11g0456300 | NP_001176525.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
We also show that SKR-1/2 functions upstream of the WD40 repeat protein WDR-23, which binds to and inhibits SKN-1. Together, these results identify a novel p38 MAPK independent signaling mechanism that activates SKN-1 via SKR-1/2 and involves WDR-23.
Title: The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK.
study found stereotyped developmental elimination of synapses in the motor neuron (HSNL) was mediated by a Skp1-cullin-F-box (SCF) complex composed of SKR-1 & SEL-10; SYG-1 bound to SKR-1 & inhibited assembly of the SCF complex, protecting nearby synapses
Title: Spatial regulation of an E3 ubiquitin ligase directs selective synapse elimination.
The following skr-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the skr-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
| CloneID | OCa335717 | |
| Clone ID Related Accession (Same CDS sequence) | NM_060112.5 , NM_060112.6 | |
| Accession Version | NM_060112.5 | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-04-08 | |
| Organism | Caenorhabditis elegans | |
| Product | Skp1-related protein | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_060112.4. COMPLETENESS: incomplete on both ends. | |
1 | ATGGCTGATC AAAAGAAAGT ATCCGAGGCG GCAAAGGAAC GCGAAATCAA GATATCGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_492513.1 |
| CDS | 1..531 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_060112.5 |
1 | ATGGCTGATC AAAAGAAAGT ATCCGAGGCG GCAAAGGAAC GCGAAATCAA GATATCGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| CloneID | OCa335717 | |
| Clone ID Related Accession (Same CDS sequence) | NM_060112.5 , NM_060112.6 | |
| Accession Version | NM_060112.6 Latest version! | Documents for ORF clone product in default vector |
| Sequence Information | ORF Nucleotide Sequence (Length: 531bp) Protein sequence SNP |
|
| Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
| Clone information | Clone Map | MSDS |
| Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
| ORF Insert Method | CloneEZ™ Seamless cloning technology | |
| Insert Structure | linear | |
| Update Date | 2019-10-17 | |
| Organism | Caenorhabditis elegans | |
| Product | Skp1-related protein | |
| Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_060112.5. | |
1 | ATGGCTGATC AAAAGAAAGT ATCCGAGGCG GCAAAGGAAC GCGAAATCAA GATATCGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
| RefSeq | NP_492513.1 |
| CDS | 15..545 |
| Translation |
Target ORF information:
Target ORF information:
|
NM_060112.6 |
1 | ATGGCTGATC AAAAGAAAGT ATCCGAGGCG GCAAAGGAAC GCGAAATCAA GATATCGTCT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |