Gene Symbol | lmn-1 |
Entrez Gene ID | 172687 |
Full Name | Lamin-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » lmn-1 cDNA ORF clone
Gene Symbol | lmn-1 |
Entrez Gene ID | 172687 |
Full Name | Lamin-1 |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_059970.4 | NP_492371.1 | Lamin-1 |
NM_059970.5 | NP_492371.1 | Lamin-1 |
LMNB1 | XP_001097340.1 | |
Rattus norvegicus (Norway rat) | Lmnb1 | NP_446357.1 |
Gallus gallus (chicken) | LMNB1 | NP_990617.1 |
Xenopus tropicalis (tropical clawed frog) | lmnb1 | NP_989198.1 |
Canis lupus familiaris (dog) | LMNB1 | XP_531892.3 |
Mus musculus (house mouse) | Lmnb1 | NP_034851.2 |
Caenorhabditis elegans (roundworm) | lmn-1 | NP_492371.1 |
Homo sapiens (human) | LMNB1 | NP_005564.1 |
Danio rerio (zebrafish) | lmnb1 | NP_694504.2 |
Pan troglodytes (chimpanzee) | LMNB1 | XP_001158070.2 |
Bos taurus (cattle) | LMNB1 | NP_001096765.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The Caenorhabditis elegans lamin, LMN-1, is required for nuclear migration and interacts with the nucleoplasmic domain of the SUN protein UNC-84.
Title: The Caenorhabditis elegans SUN protein UNC-84 interacts with lamin to transfer forces from the cytoplasm to the nucleoskeleton during nuclear migration.
In LMN-1 Y59C (a point mutation)-expressing worms, there is abnormal retention at the nuclear envelope of a gene array bearing a muscle-specific promoter. This correlates with altered expression of a number of muscle-specific genes.
Title: An EDMD mutation in C. elegans lamin blocks muscle-specific gene relocation and compromises muscle integrity.
A laminopathic mutation disrupting lamin filament assembly causes disease-like phenotypes in Caenorhabditis elegans.
Title: A laminopathic mutation disrupting lamin filament assembly causes disease-like phenotypes in Caenorhabditis elegans.
Both lamin Dm0 and C. elegans Ce-lamin bind directly to histone H2A in vitro and this binding requires a nuclear localization signal
Title: Specific and conserved sequences in D. melanogaster and C. elegans lamins and histone H2A mediate the attachment of lamins to chromosomes.
documented that the single nuclear lamin of C. elegans assembles in low ionic strength Tris-HCl buffer into stable 10-nm filaments that exhibit a normal intermediate filament morphology
Title: The single nuclear lamin of Caenorhabditis elegans forms in vitro stable intermediate filaments and paracrystals with a reduced axial periodicity.
The following lmn-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the lmn-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa335875 | |
Clone ID Related Accession (Same CDS sequence) | NM_059970.4 , NM_059970.5 | |
Accession Version | NM_059970.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Lamin-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059970.3. COMPLETENESS: incomplete on both ends. |
1 | ATGTCATCTC GTAAAGGTAC TCGTAGTTCT CGTATTGTTA CGCTAGAGCG CTCAGCGAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492371.1 |
CDS | 1..1701 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059970.4 |
1 | ATGTCATCTC GTAAAGGTAC TCGTAGTTCT CGTATTGTTA CGCTAGAGCG CTCAGCGAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa335875 | |
Clone ID Related Accession (Same CDS sequence) | NM_059970.4 , NM_059970.5 | |
Accession Version | NM_059970.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1701bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Lamin-1 | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059970.4. |
1 | ATGTCATCTC GTAAAGGTAC TCGTAGTTCT CGTATTGTTA CGCTAGAGCG CTCAGCGAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492371.1 |
CDS | 16..1716 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059970.5 |
1 | ATGTCATCTC GTAAAGGTAC TCGTAGTTCT CGTATTGTTA CGCTAGAGCG CTCAGCGAAT |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |