Gene Symbol | wdr-23 |
Entrez Gene ID | 172518 |
Full Name | DDB1-and CUL4-associated factor 11 homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » wdr-23 cDNA ORF clone
Gene Symbol | wdr-23 |
Entrez Gene ID | 172518 |
Full Name | DDB1-and CUL4-associated factor 11 homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_059723.4 | NP_492124.1 | DDB1-and CUL4-associated factor 11 homolog |
NM_059723.5 | NP_492124.1 | DDB1-and CUL4-associated factor 11 homolog |
NM_001263616.2 | NP_001250545.1 | WD_REPEATS_REGION domain-containing protein |
NM_059724.3 | NP_492125.1 | DDB1-and CUL4-associated factor 11 homolog |
NM_001306353.1 | NP_001293282.1 | DDB1-and CUL4-associated factor 11 homolog |
NM_001306354.1 | NP_001293283.1 | DDB1-and CUL4-associated factor 11 homolog |
NM_059724.4 | NP_492125.1 | DDB1-and CUL4-associated factor 11 homolog |
NM_001263616.1 | NP_001250545.1 | DDB1-and CUL4-associated factor 11 homolog |
NM_001306353.2 | NP_001293282.1 | WD_REPEATS_REGION domain-containing protein |
NM_001306354.2 | NP_001293283.1 | WD_REPEATS_REGION domain-containing protein |
Mus musculus (house mouse) | Dcaf11 | NP_598495.1 |
Drosophila melanogaster (fruit fly) | CG9945 | NP_725981.1 |
Caenorhabditis elegans (roundworm) | wdr-23 | NP_492125.1 |
Oryza sativa (rice) | Os05g0144100 | NP_001054622.1 |
Homo sapiens (human) | DCAF11 | NP_079506.3 |
Pan troglodytes (chimpanzee) | DCAF11 | XP_509863.3 |
Xenopus tropicalis (tropical clawed frog) | dcaf11 | NP_001005697.1 |
DCAF11 | XP_001111231.1 | |
Canis lupus familiaris (dog) | DCAF11 | XP_849825.1 |
Bos taurus (cattle) | DCAF11 | NP_001014954.1 |
Rattus norvegicus (Norway rat) | Dcaf11 | NP_001009686.1 |
Danio rerio (zebrafish) | dcaf11 | NP_001026845.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
a missense mutation in the conserved XREP-4 F-box domain that reduces interaction with SKR-1 but not WDR-23 strongly attenuates SKN-1-dependent gene activation. These results are consistent with XREP-4 influencing the SKN-1 stress response by functioning as a bridge between WDR-23 and the ubiquitin ligase component SKR-1.
Title: F-Box Protein XREP-4 Is a New Regulator of the Oxidative Stress Response in
ur results identify WDR23 as an alternative regulator of NRF2 proteostasis and uncover a cellular pathway that regulates NRF2 activity and capacity for cytoprotection independently of KEAP1.
Title: WDR23 regulates NRF2 independently of KEAP1.
We also show that SKR-1/2 functions upstream of the WD40 repeat protein WDR-23, which binds to and inhibits SKN-1. Together, these results identify a novel p38 MAPK independent signaling mechanism that activates SKN-1 via SKR-1/2 and involves WDR-23.
Title: The Skp1 Homologs SKR-1/2 Are Required for the Caenorhabditis elegans SKN-1 Antioxidant/Detoxification Response Independently of p38 MAPK.
diverse wdr-23 phenotypes are dependent on SKN-1; beneficial and detrimental phenotypes of wdr-23 and skn-1 can be partially decoupled; SKN-1 activation delays degenerative tissue changes during aging
Title: Characterization of skn-1/wdr-23 phenotypes in Caenorhabditis elegans; pleiotrophy, aging, glutathione, and interactions with other longevity pathways.
The following wdr-23 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the wdr-23 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa336075 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306353.1 , NM_001306353.2 | |
Accession Version | NM_001306353.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1497bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DDB1-and CUL4-associated factor 11 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGACACCAC ATGAGGAGCA GCAAATGTTT GAAAGGGAAC AACATATTGC ATTTAGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293282.1 |
CDS | 1..1497 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306353.1 |
1 | ATGACACCAC ATGAGGAGCA GCAAATGTTT GAAAGGGAAC AACATATTGC ATTTAGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336075 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306353.1 , NM_001306353.2 | |
Accession Version | NM_001306353.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1497bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | WD_REPEATS_REGION domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001306353.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGACACCAC ATGAGGAGCA GCAAATGTTT GAAAGGGAAC AACATATTGC ATTTAGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293282.1 |
CDS | 1..1497 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306353.2 |
1 | ATGACACCAC ATGAGGAGCA GCAAATGTTT GAAAGGGAAC AACATATTGC ATTTAGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336076 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306354.1 , NM_001306354.2 | |
Accession Version | NM_001306354.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DDB1-and CUL4-associated factor 11 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGACACCAC ATGAGGAGCA GCAAATGTTT GAAAGGGAAC AACATATTGC ATTTAGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293283.1 |
CDS | 1..1473 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306354.1 |
1 | ATGACACCAC ATGAGGAGCA GCAAATGTTT GAAAGGGAAC AACATATTGC ATTTAGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336076 | |
Clone ID Related Accession (Same CDS sequence) | NM_001306354.1 , NM_001306354.2 | |
Accession Version | NM_001306354.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1473bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | WD_REPEATS_REGION domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001306354.1. COMPLETENESS: incomplete on the 5' end. |
1 | ATGACACCAC ATGAGGAGCA GCAAATGTTT GAAAGGGAAC AACATATTGC ATTTAGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001293283.1 |
CDS | 1..1473 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001306354.2 |
1 | ATGACACCAC ATGAGGAGCA GCAAATGTTT GAAAGGGAAC AACATATTGC ATTTAGTGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336251 | |
Clone ID Related Accession (Same CDS sequence) | NM_059724.3 , NM_059724.4 | |
Accession Version | NM_059724.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DDB1-and CUL4-associated factor 11 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059724.2. COMPLETENESS: incomplete on both ends. |
1 | ATGCCTTACA AAAGACATTC CTCTTCAAAT CTGAAAAGGA ATCACAGCAA TGACAGTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492125.1 |
CDS | 1..1593 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059724.3 |
1 | ATGCCTTACA AAAGACATTC CTCTTCAAAT CTGAAAAGGA ATCACAGCAA TGACAGTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336251 | |
Clone ID Related Accession (Same CDS sequence) | NM_059724.3 , NM_059724.4 | |
Accession Version | NM_059724.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1593bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | DDB1-and CUL4-associated factor 11 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059724.3. |
1 | ATGCCTTACA AAAGACATTC CTCTTCAAAT CTGAAAAGGA ATCACAGCAA TGACAGTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492125.1 |
CDS | 161..1753 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059724.4 |
1 | ATGCCTTACA AAAGACATTC CTCTTCAAAT CTGAAAAGGA ATCACAGCAA TGACAGTGAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336571 | |
Clone ID Related Accession (Same CDS sequence) | NM_001263616.2 , NM_001263616.1 | |
Accession Version | NM_001263616.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | WD_REPEATS_REGION domain-containing protein | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_001263616.1. |
1 | ATGGGCAACT GGATAACGTC GACGTTCCTC CGATTTGATC TTTTTCAACG TCATCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001250545.1 |
CDS | 20..1711 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001263616.2 |
1 | ATGGGCAACT GGATAACGTC GACGTTCCTC CGATTTGATC TTTTTCAACG TCATCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336571 | |
Clone ID Related Accession (Same CDS sequence) | NM_001263616.2 , NM_001263616.1 | |
Accession Version | NM_001263616.1 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1692bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DDB1-and CUL4-associated factor 11 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). COMPLETENESS: incomplete on both ends. |
1 | ATGGGCAACT GGATAACGTC GACGTTCCTC CGATTTGATC TTTTTCAACG TCATCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001250545.1 |
CDS | 1..1692 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001263616.1 |
1 | ATGGGCAACT GGATAACGTC GACGTTCCTC CGATTTGATC TTTTTCAACG TCATCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337376 | |
Clone ID Related Accession (Same CDS sequence) | NM_059723.4 , NM_059723.5 | |
Accession Version | NM_059723.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1716bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | DDB1-and CUL4-associated factor 11 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059723.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGGCAACT GGATAACGTC GACGTTCCTC CGATTTGATC TTTTTCAACG TCATCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492124.1 |
CDS | 1..1716 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059723.4 |
1 | ATGGGCAACT GGATAACGTC GACGTTCCTC CGATTTGATC TTTTTCAACG TCATCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa337376 | |
Clone ID Related Accession (Same CDS sequence) | NM_059723.4 , NM_059723.5 | |
Accession Version | NM_059723.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1716bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | DDB1-and CUL4-associated factor 11 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059723.4. |
1 | ATGGGCAACT GGATAACGTC GACGTTCCTC CGATTTGATC TTTTTCAACG TCATCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_492124.1 |
CDS | 20..1735 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059723.5 |
1 | ATGGGCAACT GGATAACGTC GACGTTCCTC CGATTTGATC TTTTTCAACG TCATCAGCCC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |