Gene Symbol | unc-94 |
Entrez Gene ID | 172275 |
Full Name | Tropomodulin |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » unc-94 cDNA ORF clone
Gene Symbol | unc-94 |
Entrez Gene ID | 172275 |
Full Name | Tropomodulin |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_059334.3 | NP_491735.1 | Tropomodulin |
NM_059333.3 | NP_491734.1 | Tropomodulin |
NM_059333.4 | NP_491734.1 | Tropomodulin |
NM_059334.4 | NP_491735.1 | Tropomodulin |
Mus musculus (house mouse) | Tmod1 | NP_068683.1 |
Drosophila melanogaster (fruit fly) | tmod | NP_001247372.1 |
Caenorhabditis elegans (roundworm) | unc-94 | NP_491734.1 |
Gallus gallus (chicken) | TMOD1 | NP_990358.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP000969 | XP_003437160.1 |
Pan troglodytes (chimpanzee) | TMOD1 | XP_520136.3 |
TMOD1 | XP_001114190.1 | |
Canis lupus familiaris (dog) | TMOD1 | XP_532002.2 |
Homo sapiens (human) | TMOD1 | NP_001159588.1 |
Bos taurus (cattle) | TMOD1 | NP_001073108.1 |
Danio rerio (zebrafish) | tmod1 | XP_001920602.1 |
Rattus norvegicus (Norway rat) | Tmod1 | NP_037176.2 |
Xenopus tropicalis (tropical clawed frog) | tmod1 | XP_004910958.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
The data support a model in which minus-end actin capping by UNC-94 promotes proper F-actin structure and contraction in the terminal web, yielding proper shape of the intestinal lumen.
Title: The minus-end actin capping protein, UNC-94/tropomodulin, regulates development of the Caenorhabditis elegans intestine.
In vitro, UNC-94 acts in combination with HMP-1, leading to longer actin bundles than with HMP-1 alone.
Title: Tropomodulin protects ?-catenin-dependent junctional-actin networks under stress during epithelial morphogenesis.
study shows that the mutationally identified gene unc-94 corresponds with the sequence-predicted gene tmd-1 (C06A5.7), which encodes a tropomodulin
Title: unc-94 encodes a tropomodulin in Caenorhabditis elegans.
cTmd1 consists of AAs 196-392. The chain is well defined in the 2Fo-Fc map for the range 222-388. Much of the N-terminus, including AAs 196-221, is entirely disordered. The C-terminus of cTmd1 has 6 additional AAs. 4 of them (389-392) are disordered.
Title: Structural genomics of Caenorhabditis elegans: crystal structure of the tropomodulin C-terminal domain.
C-terminal part of tropomodulin protein 1, isoform A, from Caenorhabditis elegans was expressed in Escherichia coli and purified to homogeneity
Title: Purification, nanocrystallization and preliminary X-ray analysis of a C-terminal part of tropomodulin protein 1, isoform A, from Caenorhabditis elegans.
The following unc-94 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the unc-94 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa336323 | |
Clone ID Related Accession (Same CDS sequence) | NM_059333.3 , NM_059333.4 | |
Accession Version | NM_059333.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Tropomodulin | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059333.2. COMPLETENESS: incomplete on both ends. |
1 | ATGAGTCAGG CTAAAACTGA TTACTATTCT GAAGAGAAGA CCTTCTCAGC ACCGTCAGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491734.1 |
CDS | 1..1179 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059333.3 |
1 | ATGAGTCAGG CTAAAACTGA TTACTATTCT GAAGAGAAGA CCTTCTCAGC ACCGTCAGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336323 | |
Clone ID Related Accession (Same CDS sequence) | NM_059333.3 , NM_059333.4 | |
Accession Version | NM_059333.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1179bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Tropomodulin | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059333.3. |
1 | ATGAGTCAGG CTAAAACTGA TTACTATTCT GAAGAGAAGA CCTTCTCAGC ACCGTCAGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491734.1 |
CDS | 261..1439 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059333.4 |
1 | ATGAGTCAGG CTAAAACTGA TTACTATTCT GAAGAGAAGA CCTTCTCAGC ACCGTCAGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336324 | |
Clone ID Related Accession (Same CDS sequence) | NM_059334.3 , NM_059334.4 | |
Accession Version | NM_059334.3 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1206bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Tropomodulin | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059334.2. COMPLETENESS: incomplete on both ends. |
1 | ATGAGTAACA TGGAGCCTCC ACCACCCATG TTTCCTAGAT CACGAATTTA TCATAGTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491735.1 |
CDS | 1..1206 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059334.3 |
1 | ATGAGTAACA TGGAGCCTCC ACCACCCATG TTTCCTAGAT CACGAATTTA TCATAGTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336324 | |
Clone ID Related Accession (Same CDS sequence) | NM_059334.3 , NM_059334.4 | |
Accession Version | NM_059334.4 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1206bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Tropomodulin | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059334.3. |
1 | ATGAGTAACA TGGAGCCTCC ACCACCCATG TTTCCTAGAT CACGAATTTA TCATAGTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491735.1 |
CDS | 148..1353 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059334.4 |
1 | ATGAGTAACA TGGAGCCTCC ACCACCCATG TTTCCTAGAT CACGAATTTA TCATAGTTAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |