Gene Symbol | slx-1 |
Entrez Gene ID | 172157 |
Full Name | Structure-specific endonuclease subunit SLX1 homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
ORF » Species Summary » Caenorhabditis elegans » slx-1 cDNA ORF clone
Gene Symbol | slx-1 |
Entrez Gene ID | 172157 |
Full Name | Structure-specific endonuclease subunit SLX1 homolog |
Gene Type | protein-coding |
Organism | Caenorhabditis elegans |
mRNA | Protein | Name |
---|---|---|
NM_059140.4 | NP_491541.1 | Structure-specific endonuclease subunit SLX1 homolog |
NM_059140.5 | NP_491541.1 | Structure-specific endonuclease subunit SLX1 homolog |
Homo sapiens (human) | SLX1A | NP_001014999.1 |
Homo sapiens (human) | SLX1B | NP_076949.1 |
Rattus norvegicus (Norway rat) | Slx1b | NP_001009292.1 |
Caenorhabditis elegans (roundworm) | slx-1 | NP_491541.1 |
Schizosaccharomyces pombe (fission yeast) | slx1 | NP_593420.1 |
SLX1B | XP_001109511.1 | |
Mus musculus (house mouse) | Slx1b | NP_083696.2 |
Danio rerio (zebrafish) | LOC100001845 | XP_001337124.1 |
Xenopus tropicalis (tropical clawed frog) | slx1a | XP_002943477.2 |
Bos taurus (cattle) | SLX1A | NP_001032533.1 |
Drosophila melanogaster (fruit fly) | slx1 | NP_649484.3 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP002259 | XP_565552.4 |
Canis lupus familiaris (dog) | SLX1A | XP_849594.1 |
Genome sequence of the nematode C. elegans: a platform for investigating biology.
Science (New York, N.Y.)282(5396)2012-8(1998 Dec)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
Our results are consistent with the existence of at least two redundant meiotic resolvase activities: one requiring HIM-6 and XPF-1, and the other dependent on SLX-1 and MUS-81.
Title: Combinatorial regulation of meiotic holliday junction resolution in C. elegans by HIM-6 (BLM) helicase, SLX-4, and the SLX-1, MUS-81 and XPF-1 nucleases.
SLX-1 shows a HIM-18/SLX-4-dependent endonuclease activity toward replication forks, 5'-flaps, and Holliday junctions. slx-1 mutants exhibit hypersensitivity to UV, nitrogen mustard, and camptothecin, but not gamma irradiation.
Title: SLX-1 is required for maintaining genomic integrity and promoting meiotic noncrossovers in the Caenorhabditis elegans germline.
The following slx-1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the slx-1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OCa336641 | |
Clone ID Related Accession (Same CDS sequence) | NM_059140.4 , NM_059140.5 | |
Accession Version | NM_059140.4 | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-04-08 | |
Organism | Caenorhabditis elegans | |
Product | Structure-specific endonuclease subunit SLX1 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Jun 26, 2012 this sequence version replaced NM_059140.3. COMPLETENESS: incomplete on both ends. |
1 | ATGGAGACAT TCATATTGTC GTCTGATTCT GATGATGATT CTGGACCACC ACCATCAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491541.1 |
CDS | 1..1332 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059140.4 |
1 | ATGGAGACAT TCATATTGTC GTCTGATTCT GATGATGATT CTGGACCACC ACCATCAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OCa336641 | |
Clone ID Related Accession (Same CDS sequence) | NM_059140.4 , NM_059140.5 | |
Accession Version | NM_059140.5 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 1332bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-17 | |
Organism | Caenorhabditis elegans | |
Product | Structure-specific endonuclease subunit SLX1 homolog | |
Comment | Comment: REVIEWED REFSEQ: This record has been curated by WormBase. This record is derived from an annotated genomic sequence (NC_003279). On Sep 4, 2019 this sequence version replaced NM_059140.4. COMPLETENESS: incomplete on the 5' end. |
1 | ATGGAGACAT TCATATTGTC GTCTGATTCT GATGATGATT CTGGACCACC ACCATCAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_491541.1 |
CDS | 1..1332 |
Translation |
Target ORF information:
Target ORF information:
|
NM_059140.5 |
1 | ATGGAGACAT TCATATTGTC GTCTGATTCT GATGATGATT CTGGACCACC ACCATCAAAA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Genome sequence of the nematode C. elegans: a platform for investigating biology. |