KL cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	KL
Entrez Gene ID	784635
Full Name	klotho
General protein information	Preferred Names klotho Names klotho
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001191195.1	NP_001178124.1	klotho precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KL	XP_522655.2
	LOC714042	XP_001101127.1
Homo sapiens (human)	KL	NP_004786.2
Canis lupus familiaris (dog)	KL	XP_003433357.1
Bos taurus (cattle)	KL	NP_001178124.1
Mus musculus (house mouse)	Kl	NP_038851.2
Danio rerio (zebrafish)	kl	XP_690797.4
Rattus norvegicus (Norway rat)	Kl	NP_112626.1
Gallus gallus (chicken)	KL	XP_004938814.1
Xenopus tropicalis (tropical clawed frog)	kl	XP_002934067.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

The following KL gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KL cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa01770	NM_001191195.1 Latest version!	Bos taurus klotho (KL), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$629.30 $899.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KL ( NM_001191195.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001178124.1 Bos taurus klotho (KL), mRNA.

Price & Availability↑

CloneID	OBa01770
Clone ID Related Accession (Same CDS sequence)	NM_001191195.1
Accession Version	NM_001191195.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 3042bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2011-11-13
Organism	Bos taurus(cattle)
Product	klotho precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AAFC03093308.1. On Jul 17, 2010 this sequence version replaced XM_001252499.1. Sequence Note: The RefSeq transcript and protein were derived from genomic sequence to make the sequence consistent with the reference genome assembly. The genomic coordinates used for the transcript record were based on alignments.

ATGCCCGCCC GCGCCCCGCC GCGCCGCCTG CGGGCGTTTC CGCCGCCGCC GCCGCCGCTG 
TGGCTGCTAC TGCTGGCCCT GGGCGGTCGC CCCCTGCGCG CCGAGCCCGG CGACGGCGCG 
CAGACCTGGG CCCGCTTCGC GCGCCCTCCG ACCCCCGAGG CCGCGGGGCT ACTCCACGAC 
ACCTTCCCCG ACGGCTTCCT CTGGGCCGTG GGCAGCGCTG CCTACCAGAC GGAGGGCGGC 
TGGCAGCAGC ACGGCAAGGG CGCCTCCATC TGGGACACGT TCACCCACCG CCCCCCGGCG 
CCTCCAGGCG ACCCCTCGGC GGCCGGCTGG CCGTCGGGCG CCCCGTCGCC CCCCCCGCCC 
GCCACCGGGG ACGTGGCCAG CGACGGCTAC AACAATGTCT TTCGAGACAC GGAGGGGCTG 
CGCGAGCTCG GGGTCACCCA TTACCGCTTC TCCATCTCGT GGGCGCGGGT GCTCCCCAAT 
GGCAGCGCCA GCGCCCCCAA CCGGGAGGGG CTGCGCTACT ACCGGCGTCT GCTGGAGCGG 
CTGCGGGAGC TGGGCGTGCA GCCCGTGGTC ACCTTGTACC ACTGGGACCT GCCCCAGCGC 
CTGCAGGATG CCTACGGCGG CTGGGCCAAC CGCGCCCTGG CCGACCACTT CAGGGATTAC 
GCCGAGCTCT GCTTCCGCCA CTTCGGCGGC CAGGTCAAGT ACTGGATCAC CATCGACAAC 
CCCTACGTGG TGGCCTGGCA CGGCTACGCC ACAGGGCGCC TGGCTCCCGG CGTCCGGGGC 
AGCCCGCGAC TCGGTTACCT GGTGGCGCAC AACCTCCTCC TGGCTCATGC CAAAATCTGG 
CATCTCTACG ATACTTCCTT CCGCCCCACT CAGGGAGGCC AGGTGTCCAT TGCCCTAAGC 
TCCCACTGGA TCAGTCCTCG AAGAATGACT GAACACAGCA TCCAAGAATG TCAAAAATCT 
CTTGACTTTG TCCTGGGCTG GTTTGCCAAA CCCATATTTA TTGATGGAGA CTATCCTGAG 
AGCATGAAGA ATAACCTTTC ATCTCTTCTG CCTGATTTTA CTGAATCTGA GAAGAAGTTC 
ATCAAGGGAA CAGCCGACTT TTTTGCTCTT TCCTTTGGCC CGACCTTGAG TTTTCAACTG 
TTGGACCCTC AGATGAAATT CCGCCAACTG GAATCTCCCA GCCTGAGGCA ACTCCTTTCC 
TGGATTGACC TTGAGTATAA CCACCCTCAA ATCTTTATTG TGGAGAATGG CTGGTTTGTT 
TCCGGGACCA CCAAGAGAGA TGATGCCAAA TACATGTATT ACCTCAAAAA ATTCATAATG 
GAGACCTTAA AAGCCATCAG GTTGGACGGG GTGGATGTCA TTGGGTACAC GGCCTGGTCA 
CTCATGGATG GCTTCGAGTG GCACCGGGGC TACAGCATCA GACGTGGACT CTTCTACGTT 
GACTTTCTAA GCCAGGACAA GAAGCTGTTG CCGAAGTCTT CAGCCTTGTT CTACCAAAAG 
CTGATAGAGA ACAATGGCTT CCCTCCTTTA CCTGAAAACC AACCCCTAGA AGGGACATTT 
CCCTGTGACT TTGCTTGGGG AGTTGTTGAC AACTGCATTC AAGTGGACAC CACCCTGTCT 
CAGTTCATTG ACCCCAACGT CTACCTGTGG GATGTCCACC GCAGTAAGAG GCTCATCAAG 
GTGGATGGGG TTCTGACCAA GACGAGGAAA TCCTACTGCG TGGACTTCGC CGCCATCCGA 
CCCCAGATCG CCTTACTCCA GGAAATGCAC GTGACTCATT TCCACTTCTC GCTGGACTGG 
GCGCTGATTC TGCCGCTGGG GAACCGGTCC CAGGTCAATC GCACGGTCCT GGGGTTCTAC 
CGCTGTGTGG CCAGCGAGCT GGTGCGCGCC AACATCACCC CGGTGGTGGC GCTGTGGCGC 
CCGGCCGCCC CGCACCAGGG ACTGCCGGCC CCCCTGGCCC GGCACGGCGC CTGGGAGAAC 
CCCCACACCG CCCTGGCCTT TGCCGAGTAT GCCAGCCTGT GCTTTCAAGA CCTCGGCCGC 
CACGTCAAGT TCTGGATCAC GATGCACGAG CCGTCCACGC GGAACATGAC CTACAGCGCG 
GGGCACAACC TCCTGAAGGC GCACGCGCTG GCCTGGCGCA CGTATGATGA GAGGTTCAGG 
CGCTCGCAGA AAGGAAAAAT ATCCATCGCC CTGCAGGCGG ACTGGATAGA ACCCGCCTGC 
CCTTTCTCCC CGGAGGACCG CGAGGTGGCT GAGCGAGTTC TGGAATTTGA CATCGGTTGG 
CTGGCCGAGC CCATTTTCGG CTCCGGGGAT TATCCACGCG TGATGAGAGA CTGGCTGAAC 
CAGAGAAACA ATTTCCTGCT CCCTTATTTC ACTGACGAGG AAAAAAAGCT AATCCGGGGT 
TCCTTTGACT TTTTGGCGTT GAGCCATTAC ACTACCATCC TTGTAGACTG GGAGAAAGAA 
GATCCCATAA AATACAACGA TTACCTGGCC GTGCAAGAAA TGACCGACAT CACCTGGCTC 
AACTCCCCCA GTCAGGTGGC CGTGGTGCCC TGGGGGTTAC GCAAGGTACT GAACTGGCTG 
AAGGCCAAGT ACGGAGACCT CCCCATGTAT ATCATATCCA ACGGCATCGA TGATGATCCG 
CACGCAGCCC AGGACAATCT GAGGGTGTAT TACATGCAGA CTTACGTGAA CGAAGCTCTG 
AAAGCCTATA TATTGGATGG TATCAATCTT TGTGGATACT TTGCTTATTC ATTTAACGAC 
CGCACAGCTC CGAAGTTTGG CCTCTATCGT TATGCGGCAA ATCAGTTTGA GCCCAAACCA 
TCAATGAAAC ATTACAGGAA AATTATAGAC AACAATGGCT TTCCAGGTCC TGAAACTCTG 
GGAAGATTTT GTCCAGAAGA ATTCACCCTG TGTACAGAGT GCAGCTTTTT TCATACCCGA 
AAGTCTTTAC TGGCTTTCAT AGCTTTTCTA CTTTTTGCCT TTGTTATTTC TCTTTCTCTG 
ATTTTTTACT ACTCTAAGAA AGGCAGAAGA GGTTACAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001178124.1
CDS	1..3042
Translation	MPARAPPRRLRAFPPPPPPLWLLLLALGGRPLRAEPGDGAQTWARFARPPTPEAAGLLHDTFPDGFLWAVGSAAYQTEGGWQQHGKGASIWDTFTHRPPAPPGDPSAAGWPSGAPSPPPPATGDVASDGYNNVFRDTEGLRELGVTHYRFSISWARVLPNGSASAPNREGLRYYRRLLERLRELGVQPVVTLYHWDLPQRLQDAYGGWANRALADHFRDYAELCFRHFGGQVKYWITIDNPYVVAWHGYATGRLAPGVRGSPRLGYLVAHNLLLAHAKIWHLYDTSFRPTQGGQVSIALSSHWISPRRMTEHSIQECQKSLDFVLGWFAKPIFIDGDYPESMKNNLSSLLPDFTESEKKFIKGTADFFALSFGPTLSFQLLDPQMKFRQLESPSLRQLLSWIDLEYNHPQIFIVENGWFVSGTTKRDDAKYMYYLKKFIMETLKAIRLDGVDVIGYTAWSLMDGFEWHRGYSIRRGLFYVDFLSQDKKLLPKSSALFYQKLIENNGFPPLPENQPLEGTFPCDFAWGVVDNCIQVDTTLSQFIDPNVYLWDVHRSKRLIKVDGVLTKTRKSYCVDFAAIRPQIALLQEMHVTHFHFSLDWALILPLGNRSQVNRTVLGFYRCVASELVRANITPVVALWRPAAPHQGLPAPLARHGAWENPHTALAFAEYASLCFQDLGRHVKFWITMHEPSTRNMTYSAGHNLLKAHALAWRTYDERFRRSQKGKISIALQADWIEPACPFSPEDREVAERVLEFDIGWLAEPIFGSGDYPRVMRDWLNQRNNFLLPYFTDEEKKLIRGSFDFLALSHYTTILVDWEKEDPIKYNDYLAVQEMTDITWLNSPSQVAVVPWGLRKVLNWLKAKYGDLPMYIISNGIDDDPHAAQDNLRVYYMQTYVNEALKAYILDGINLCGYFAYSFNDRTAPKFGLYRYAANQFEPKPSMKHYRKIIDNNGFPGPETLGRFCPEEFTLCTECSFFHTRKSLLAFIAFLLFAFVISLSLIFYYSKKGRRGYK

Target ORF information:

RefSeq Version	NM_001191195.1
Organism	Bos taurus(cattle)
Definition	Bos taurus klotho (KL), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001191195.1

ORF Insert Sequence:

ATGCCCGCCC GCGCCCCGCC GCGCCGCCTG CGGGCGTTTC CGCCGCCGCC GCCGCCGCTG 
TGGCTGCTAC TGCTGGCCCT GGGCGGTCGC CCCCTGCGCG CCGAGCCCGG CGACGGCGCG 
CAGACCTGGG CCCGCTTCGC GCGCCCTCCG ACCCCCGAGG CCGCGGGGCT ACTCCACGAC 
ACCTTCCCCG ACGGCTTCCT CTGGGCCGTG GGCAGCGCTG CCTACCAGAC GGAGGGCGGC 
TGGCAGCAGC ACGGCAAGGG CGCCTCCATC TGGGACACGT TCACCCACCG CCCCCCGGCG 
CCTCCAGGCG ACCCCTCGGC GGCCGGCTGG CCGTCGGGCG CCCCGTCGCC CCCCCCGCCC 
GCCACCGGGG ACGTGGCCAG CGACGGCTAC AACAATGTCT TTCGAGACAC GGAGGGGCTG 
CGCGAGCTCG GGGTCACCCA TTACCGCTTC TCCATCTCGT GGGCGCGGGT GCTCCCCAAT 
GGCAGCGCCA GCGCCCCCAA CCGGGAGGGG CTGCGCTACT ACCGGCGTCT GCTGGAGCGG 
CTGCGGGAGC TGGGCGTGCA GCCCGTGGTC ACCTTGTACC ACTGGGACCT GCCCCAGCGC 
CTGCAGGATG CCTACGGCGG CTGGGCCAAC CGCGCCCTGG CCGACCACTT CAGGGATTAC 
GCCGAGCTCT GCTTCCGCCA CTTCGGCGGC CAGGTCAAGT ACTGGATCAC CATCGACAAC 
CCCTACGTGG TGGCCTGGCA CGGCTACGCC ACAGGGCGCC TGGCTCCCGG CGTCCGGGGC 
AGCCCGCGAC TCGGTTACCT GGTGGCGCAC AACCTCCTCC TGGCTCATGC CAAAATCTGG 
CATCTCTACG ATACTTCCTT CCGCCCCACT CAGGGAGGCC AGGTGTCCAT TGCCCTAAGC 
TCCCACTGGA TCAGTCCTCG AAGAATGACT GAACACAGCA TCCAAGAATG TCAAAAATCT 
CTTGACTTTG TCCTGGGCTG GTTTGCCAAA CCCATATTTA TTGATGGAGA CTATCCTGAG 
AGCATGAAGA ATAACCTTTC ATCTCTTCTG CCTGATTTTA CTGAATCTGA GAAGAAGTTC 
ATCAAGGGAA CAGCCGACTT TTTTGCTCTT TCCTTTGGCC CGACCTTGAG TTTTCAACTG 
TTGGACCCTC AGATGAAATT CCGCCAACTG GAATCTCCCA GCCTGAGGCA ACTCCTTTCC 
TGGATTGACC TTGAGTATAA CCACCCTCAA ATCTTTATTG TGGAGAATGG CTGGTTTGTT 
TCCGGGACCA CCAAGAGAGA TGATGCCAAA TACATGTATT ACCTCAAAAA ATTCATAATG 
GAGACCTTAA AAGCCATCAG GTTGGACGGG GTGGATGTCA TTGGGTACAC GGCCTGGTCA 
CTCATGGATG GCTTCGAGTG GCACCGGGGC TACAGCATCA GACGTGGACT CTTCTACGTT 
GACTTTCTAA GCCAGGACAA GAAGCTGTTG CCGAAGTCTT CAGCCTTGTT CTACCAAAAG 
CTGATAGAGA ACAATGGCTT CCCTCCTTTA CCTGAAAACC AACCCCTAGA AGGGACATTT 
CCCTGTGACT TTGCTTGGGG AGTTGTTGAC AACTGCATTC AAGTGGACAC CACCCTGTCT 
CAGTTCATTG ACCCCAACGT CTACCTGTGG GATGTCCACC GCAGTAAGAG GCTCATCAAG 
GTGGATGGGG TTCTGACCAA GACGAGGAAA TCCTACTGCG TGGACTTCGC CGCCATCCGA 
CCCCAGATCG CCTTACTCCA GGAAATGCAC GTGACTCATT TCCACTTCTC GCTGGACTGG 
GCGCTGATTC TGCCGCTGGG GAACCGGTCC CAGGTCAATC GCACGGTCCT GGGGTTCTAC 
CGCTGTGTGG CCAGCGAGCT GGTGCGCGCC AACATCACCC CGGTGGTGGC GCTGTGGCGC 
CCGGCCGCCC CGCACCAGGG ACTGCCGGCC CCCCTGGCCC GGCACGGCGC CTGGGAGAAC 
CCCCACACCG CCCTGGCCTT TGCCGAGTAT GCCAGCCTGT GCTTTCAAGA CCTCGGCCGC 
CACGTCAAGT TCTGGATCAC GATGCACGAG CCGTCCACGC GGAACATGAC CTACAGCGCG 
GGGCACAACC TCCTGAAGGC GCACGCGCTG GCCTGGCGCA CGTATGATGA GAGGTTCAGG 
CGCTCGCAGA AAGGAAAAAT ATCCATCGCC CTGCAGGCGG ACTGGATAGA ACCCGCCTGC 
CCTTTCTCCC CGGAGGACCG CGAGGTGGCT GAGCGAGTTC TGGAATTTGA CATCGGTTGG 
CTGGCCGAGC CCATTTTCGG CTCCGGGGAT TATCCACGCG TGATGAGAGA CTGGCTGAAC 
CAGAGAAACA ATTTCCTGCT CCCTTATTTC ACTGACGAGG AAAAAAAGCT AATCCGGGGT 
TCCTTTGACT TTTTGGCGTT GAGCCATTAC ACTACCATCC TTGTAGACTG GGAGAAAGAA 
GATCCCATAA AATACAACGA TTACCTGGCC GTGCAAGAAA TGACCGACAT CACCTGGCTC 
AACTCCCCCA GTCAGGTGGC CGTGGTGCCC TGGGGGTTAC GCAAGGTACT GAACTGGCTG 
AAGGCCAAGT ACGGAGACCT CCCCATGTAT ATCATATCCA ACGGCATCGA TGATGATCCG 
CACGCAGCCC AGGACAATCT GAGGGTGTAT TACATGCAGA CTTACGTGAA CGAAGCTCTG 
AAAGCCTATA TATTGGATGG TATCAATCTT TGTGGATACT TTGCTTATTC ATTTAACGAC 
CGCACAGCTC CGAAGTTTGG CCTCTATCGT TATGCGGCAA ATCAGTTTGA GCCCAAACCA 
TCAATGAAAC ATTACAGGAA AATTATAGAC AACAATGGCT TTCCAGGTCC TGAAACTCTG 
GGAAGATTTT GTCCAGAAGA ATTCACCCTG TGTACAGAGT GCAGCTTTTT TCATACCCGA 
AAGTCTTTAC TGGCTTTCAT AGCTTTTCTA CTTTTTGCCT TTGTTATTTC TCTTTCTCTG 
ATTTTTTACT ACTCTAAGAA AGGCAGAAGA GGTTACAAAT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

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KL cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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