Gene Symbol | DEFB5 |
Entrez Gene ID | 783935 |
Full Name | defensin, beta 5 |
Synonyms | BNDB-5 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » DEFB5 cDNA ORF clone
Gene Symbol | DEFB5 |
Entrez Gene ID | 783935 |
Full Name | defensin, beta 5 |
Synonyms | BNDB-5 |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
XM_005225939.2 | XP_005225996.1 | beta-defensin 5 isoform X1 |
NM_001130761.1 | NP_001124233.1 | beta-defensin 5 precursor |
Postpartum toll-like receptors and ?-defensin 5 mRNA levels in the endometrium of Holstein cows.
Martins Tda M, da Paix?o TA, Costa ?A, Pires Ade C, Santos RL, Borges ?M
Veterinary immunology and immunopathology139(2-4)277-81(2011 Feb)
A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)
Mastitis increases mammary mRNA abundance of beta-defensin 5, toll-like-receptor 2 (TLR2), and TLR4 but not TLR9 in cattle.
Goldammer T, Zerbe H, Molenaar A, Schuberth HJ, Brunner RM, Kata SR, Seyfert HM
Clinical and diagnostic laboratory immunology11(1)174-85(2004 Jan)
Expression of beta-defensin genes in bovine alveolar macrophages.
Ryan LK, Rhodes J, Bhat M, Diamond G
Infection and immunity66(2)878-81(1998 Feb)
Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils.
Selsted ME, Tang YQ, Morris WL, McGuire PA, Novotny MJ, Smith W, Henschen AH, Cullor JS
The Journal of biological chemistry268(9)6641-8(1993 Mar)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
This study aimed to evaluate endometrial mRNA levels of toll-like receptors and beta-defensin 5 in Holstein cows by quantitative real time RT-PCR.
Title: Postpartum toll-like receptors and ?-defensin 5 mRNA levels in the endometrium of Holstein cows.
mRNA abundances of TLR9, TLR2, and TLR4 together with those of beta-defensin 5 (BNBD5), an early bactericidal effector molecule of the innate system, in healthy and infected mammary glands
Title: Mastitis increases mammary mRNA abundance of beta-defensin 5, toll-like-receptor 2 (TLR2), and TLR4 but not TLR9 in cattle.
The following DEFB5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the DEFB5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa44090 | |
Clone ID Related Accession (Same CDS sequence) | NM_001130761.1 | |
Accession Version | NM_001130761.1 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 195bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-18 | |
Organism | Bos taurus(cattle) | |
Product | beta-defensin 5 precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ278799.1. ##Evidence-Data-START## Transcript exon combination :: BM106372.1, EV672376.1 [ECO:0000332] ##Evidence-Data-END## |
1 | ATGAGGCTCC ATCACCTGCT CCTCGTGCTC CTCTTCCTAG TCCTGTCTGC TGGGTCAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_001124233.1 |
CDS | 18..212 |
Translation |
Target ORF information:
Target ORF information:
|
NM_001130761.1 |
1 | ATGAGGCTCC ATCACCTGCT CCTCGTGCTC CTCTTCCTAG TCCTGTCTGC TGGGTCAGGA |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
CloneID | OBa33877 | |
Clone ID Related Accession (Same CDS sequence) | XM_005225939.2 | |
Accession Version | XM_005225939.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 543bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2016-01-25 | |
Organism | Bos taurus(cattle) | |
Product | beta-defensin 5 isoform X1 | |
Comment | Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NW_003104597.1) annotated using gene prediction method: Gnomon, supported by mRNA and EST evidence. Also see: Documentation of NCBI's Annotation Process On Dec 30, 2014 this sequence version replaced XM_005225939.1. ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Version :: Bos taurus Annotation Release 105 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 6.5 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END## ##RefSeq-Attributes-START## ab initio :: 18% of CDS bases ##RefSeq-Attributes-END## |
1 | ATGGCGCCCG CCCGGTCCAT AGGACAAGGG AACTGGGGAC AATGTCCTCT GCCCATTAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | XP_005225996.1 |
CDS | 1..543 |
Translation |
Target ORF information:
Target ORF information:
|
XM_005225939.2 |
1 | ATGGCGCCCG CCCGGTCCAT AGGACAAGGG AACTGGGGAC AATGTCCTCT GCCCATTAAC |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
Postpartum toll-like receptors and ?-defensin 5 mRNA levels in the endometrium of Holstein cows. |
A whole-genome assembly of the domestic cow, Bos taurus. |
Mastitis increases mammary mRNA abundance of beta-defensin 5, toll-like-receptor 2 (TLR2), and TLR4 but not TLR9 in cattle. |
Expression of beta-defensin genes in bovine alveolar macrophages. |
Purification, primary structures, and antibacterial activities of beta-defensins, a new family of antimicrobial peptides from bovine neutrophils. |