TLR10 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	TLR10
Entrez Gene ID	539791
Full Name	toll like receptor 10
General protein information	Preferred Names toll like receptor 10 Names toll-like receptor 10
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001076918.2	NP_001070386.1	toll-like receptor 10 precursor

Pathways from BioSystems

Homologies

Canis lupus familiaris (dog)	TLR10	NP_001166598.1
Bos taurus (cattle)	TLR10	NP_001070386.1
Pan troglodytes (chimpanzee)	TLR10	NP_001123936.1
Homo sapiens (human)	TLR10	NP_112218.2
	TLR10	NP_001123906.1
Rattus norvegicus (Norway rat)	Tlr10	NP_001139507.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Sequence variability and protein domain architectures for bovine Toll-like receptors 1, 5, and 10.
Seabury CM, Cargill EJ, Womack JE
Genomics90(4)502-15(2007 Oct)

Genomic organization and transcript profiling of the bovine toll-like receptor gene cluster TLR6-TLR1-TLR10.
Opsal MA, V?ge DI, Hayes B, Berget I, Lien S
Gene38445-50(2006 Dec)

Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells-potential role in pathogen discrimination?
Werling D, Piercy J, Coffey TJ
Veterinary immunology and immunopathology112(1-2)2-11(2006 Jul)

Radiation hybrid mapping of all 10 characterized bovine Toll-like receptors.
McGuire K, Jones M, Werling D, Williams JL, Glass EJ, Jann O
Animal genetics37(1)47-50(2006 Feb)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Prediction and comparison of TLR protein domain architectures for multiple species revealed seven conserved regions of LRR patterning associated with the three genes investigated.
Title: Sequence variability and protein domain architectures for bovine Toll-like receptors 1, 5, and 10.

The expression analysis showed similar expression profiles for TLR1 and TLR6, which indicate a co-regulation of these two genes, TLR10 had a different expression profile, pointing toward a stronger functional diversification compared to TLR1 and TLR6.
Title: Genomic organization and transcript profiling of the bovine toll-like receptor gene cluster TLR6-TLR1-TLR10.

The following TLR10 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the TLR10 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa00487	NM_001076918.2 Latest version!	Bos taurus toll like receptor 10 (TLR10), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

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** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

TLR10 ( NM_001076918.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001070386.1 Bos taurus toll like receptor 10 (TLR10), mRNA.

Price & Availability↑

CloneID	OBa00487
Clone ID Related Accession (Same CDS sequence)	NM_001076918.2
Accession Version	NM_001076918.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2439bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Bos taurus(cattle)
Product	toll-like receptor 10 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC123541.1. On Aug 31, 2012 this sequence version replaced NM_001076918.1. ##Evidence-Data-START## Transcript exon combination :: BC123541.1, DV828532.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145426, SAMN03145442 [ECO:0000348] ##Evidence-Data-END##

ATGAGATATA TCAGAAGCAT TTACATATTT TGTAGTATTG TTACGTCTGT GCGTAGTGGG 
GCTTCAGAGC TGCCCGAAGA AAGGGAATTG ACTACCAACT TCTCCAGCAT GTCTTTAACA 
AAGGTTCCTG AAGGCTTGAC CCCAATTACA ACCACATTGG ATTTGTCTTA TAATCTCCTT 
TTTCAACTCC AGCATTCAGA TTTCCGTTCT CTCTCTAAAC TGAAAGTTTT GATTCTATGC 
CACAACAGAA TCCAAGAGCT GGATATCAAG ACCTTTGAAT TCAACAAGGA GTTAAGCTAC 
TTAGATGTGT CTAACAACAG ACTGAAGAGT GTAACCTGGT TCTCACTGGC AGGTCTCAGA 
CATTTAGATC TGTCCTTCAA TGACTTTGAC ACTCTGCCTA TCAGCGTAGA AACTGGCAAC 
ATGTCACACC TGGAAACCCT AGGTTTGAGT GGGGCAAAAA TACAAAAATC AGATTTTCAG 
AAAATTGCTC ATTTGCAGCT AAATACCGTC TTATTAGGAT TGAGAACTCT ATCTCATTAT 
GAAGAAGGTA GCTTGCCCAT CTTAAACACA ACAAGACTTC ACATTGTGTT ACCAGTGAAC 
ACAAATTTCT GGGTTCTTTT GCATGATGGA ATCAAAACTT CAAAAATATT AGAAGTCATC 
AATATAGATT TGCAAAAGAG CCAGTTTACG AGTTATGAAT CTCAACAAAT TCCTATTTTA 
GAAAATGCCA AGACATCCAT TCTGTTACTT AATAAAGTTG ACTTATCCTG GGACGATCTT 
TTCCTCATCT TCCAATTGGT TTGGCATACA TCAGTAGAGT ACTTTCAGAT TCAACATGTG 
ACCTTTGGAG GTAAGGTTTA TCTTGACCAC AATTCATTTG ACTACTCAAA TACTGTAATG 
AGAACTATAA AACTGGAACA TGTACATTTT AGAATTTTTA ATATCCCCCA GGAGAGCATC 
TACTTGCTTT TTACCAAAAT GGATATAGAA AACCTGACAA TATCAGATGC ACAAATGCCT 
CACATGCTGT TCCCTATGTA CCCTACAAGA TTCCAATATT TAAATTTCGC TAATAATATC 
TTAACAGATG ATGTGTTTAA AAAATCTATC CAATTGCCTC ATTTGAAAAC TCTCATCTTG 
AAGGACAATA AATTGGAGAC ACTTTCCTTA GTGAGTCACT TTGCCAGCAA CACATCCCTG 
AGGCACTTAG ATCTGAGTGA AAATCTGTTA CAACATGAAA ATGATGAAAA TTGCTTGTGG 
CCAGAAACCT TGGTCACCAT GAACTTGTCA TTCAACAAAT TTGCTGATTC TGTTTTTGGG 
TGCTTGCCTA GAAACATTCA AATACTGGAC CTGAATAGTA ACAAAATTCA AACTGTCCCT 
AAAGCGATTA CTCACCTGAC ATCTTTGCGA GAGTTAAATC TTGCATTTAA TTTTCTAACT 
GATCTTCCTG GGTGCAGTCA TTTCAGAAGA CTCTTAGTTC TGAACGTTGA AATGAACTTA 
ATTCTCAGCT CATCTCTGGA TTTTTTCCAG AGCTGCCAGG AAGTTAAAAC TCTAAATGCA 
GGAAGAAATC CATTCCGATG TACTTGTGAA TTAAGAGATT TCATTCAGCT TGGAAAATAC 
TCAGAAGGCA TGATGGTTGG ATGGTCAGAT TCATACATCT GTGAATACCC TTTGAATCTA 
AAGGGGACTC AGTTAAAGGA TGTTCATCTT CCAGAAATAT CTTGCAACAC AGGTTTGCTG 
ATTGTCACCA TTGTGGTTGT CATGCTCGTT CTGGGGATGG CTGTGGCCTT CTGCTGCCTC 
CACTTTGATT TGCCCTGGTA TCTCAGGATG CTGCATCAAT GGACTCAGAC ATGGCTCAGG 
GTTAGGAAGA CAACTCAGGA ACAACTCAAA AGAAGTGTCC AATTCCATGT GTTTATTTCA 
TACAGTGAAC ATGATTCTGC CTGGGTGAAG TATGAATTGA TTCCCAGTCT AGAGAAAGAA 
GATGGTTCTG TTCTGATTTG CCTTCATGAG GGAAACTCTG ACCCTGGCAA GAGCATGACT 
GAAGATACCA TAAACTGCAT TGAGAAAAGT TACAAGTCCA TCTTTGTTTT GTCTCCCAGC 
TTTGTCCAGA CTGAATGGTG CCATTATGAA CCCTACTTTG CCCACCACAA TCTCTTCCAT 
GAAAGTCTTG ATTACATAAT TCTTATCTTA CTGGAACCCA TTCCACTCTA CTGCATCCCT 
ACCAGATATC CTGAGCTGAA AGCTCTCATG GAAAAGAAAG CATACTTGGA ATGGCCCAAG 
GATAGGCGTA AATGTGGCCT TTTTTGGGCA AACCTTCGAG CTGCTCTTCA TGTTAATTTA 
TTAGACACCA GAGGGACATG TGAACTACAG ACATTCACAG AACTGAATGA AGGGTTTGGA 
GGTTCTGCAA TCTCTCTGAT CAGAACAGAC TGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001070386.1
CDS	157..2595
Translation	MRYIRSIYIFCSIVTSVRSGASELPEERELTTNFSSMSLTKVPEGLTPITTTLDLSYNLLFQLQHSDFRSLSKLKVLILCHNRIQELDIKTFEFNKELSYLDVSNNRLKSVTWFSLAGLRHLDLSFNDFDTLPISVETGNMSHLETLGLSGAKIQKSDFQKIAHLQLNTVLLGLRTLSHYEEGSLPILNTTRLHIVLPVNTNFWVLLHDGIKTSKILEVINIDLQKSQFTSYESQQIPILENAKTSILLLNKVDLSWDDLFLIFQLVWHTSVEYFQIQHVTFGGKVYLDHNSFDYSNTVMRTIKLEHVHFRIFNIPQESIYLLFTKMDIENLTISDAQMPHMLFPMYPTRFQYLNFANNILTDDVFKKSIQLPHLKTLILKDNKLETLSLVSHFASNTSLRHLDLSENLLQHENDENCLWPETLVTMNLSFNKFADSVFGCLPRNIQILDLNSNKIQTVPKAITHLTSLRELNLAFNFLTDLPGCSHFRRLLVLNVEMNLILSSSLDFFQSCQEVKTLNAGRNPFRCTCELRDFIQLGKYSEGMMVGWSDSYICEYPLNLKGTQLKDVHLPEISCNTGLLIVTIVVVMLVLGMAVAFCCLHFDLPWYLRMLHQWTQTWLRVRKTTQEQLKRSVQFHVFISYSEHDSAWVKYELIPSLEKEDGSVLICLHEGNSDPGKSMTEDTINCIEKSYKSIFVLSPSFVQTEWCHYEPYFAHHNLFHESLDYIILILLEPIPLYCIPTRYPELKALMEKKAYLEWPKDRRKCGLFWANLRAALHVNLLDTRGTCELQTFTELNEGFGGSAISLIRTDCL

Target ORF information:

RefSeq Version	NM_001076918.2
Organism	Bos taurus(cattle)
Definition	Bos taurus toll like receptor 10 (TLR10), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001076918.2

ORF Insert Sequence:

ATGAGATATA TCAGAAGCAT TTACATATTT TGTAGTATTG TTACGTCTGT GCGTAGTGGG 
GCTTCAGAGC TGCCCGAAGA AAGGGAATTG ACTACCAACT TCTCCAGCAT GTCTTTAACA 
AAGGTTCCTG AAGGCTTGAC CCCAATTACA ACCACATTGG ATTTGTCTTA TAATCTCCTT 
TTTCAACTCC AGCATTCAGA TTTCCGTTCT CTCTCTAAAC TGAAAGTTTT GATTCTATGC 
CACAACAGAA TCCAAGAGCT GGATATCAAG ACCTTTGAAT TCAACAAGGA GTTAAGCTAC 
TTAGATGTGT CTAACAACAG ACTGAAGAGT GTAACCTGGT TCTCACTGGC AGGTCTCAGA 
CATTTAGATC TGTCCTTCAA TGACTTTGAC ACTCTGCCTA TCAGCGTAGA AACTGGCAAC 
ATGTCACACC TGGAAACCCT AGGTTTGAGT GGGGCAAAAA TACAAAAATC AGATTTTCAG 
AAAATTGCTC ATTTGCAGCT AAATACCGTC TTATTAGGAT TGAGAACTCT ATCTCATTAT 
GAAGAAGGTA GCTTGCCCAT CTTAAACACA ACAAGACTTC ACATTGTGTT ACCAGTGAAC 
ACAAATTTCT GGGTTCTTTT GCATGATGGA ATCAAAACTT CAAAAATATT AGAAGTCATC 
AATATAGATT TGCAAAAGAG CCAGTTTACG AGTTATGAAT CTCAACAAAT TCCTATTTTA 
GAAAATGCCA AGACATCCAT TCTGTTACTT AATAAAGTTG ACTTATCCTG GGACGATCTT 
TTCCTCATCT TCCAATTGGT TTGGCATACA TCAGTAGAGT ACTTTCAGAT TCAACATGTG 
ACCTTTGGAG GTAAGGTTTA TCTTGACCAC AATTCATTTG ACTACTCAAA TACTGTAATG 
AGAACTATAA AACTGGAACA TGTACATTTT AGAATTTTTA ATATCCCCCA GGAGAGCATC 
TACTTGCTTT TTACCAAAAT GGATATAGAA AACCTGACAA TATCAGATGC ACAAATGCCT 
CACATGCTGT TCCCTATGTA CCCTACAAGA TTCCAATATT TAAATTTCGC TAATAATATC 
TTAACAGATG ATGTGTTTAA AAAATCTATC CAATTGCCTC ATTTGAAAAC TCTCATCTTG 
AAGGACAATA AATTGGAGAC ACTTTCCTTA GTGAGTCACT TTGCCAGCAA CACATCCCTG 
AGGCACTTAG ATCTGAGTGA AAATCTGTTA CAACATGAAA ATGATGAAAA TTGCTTGTGG 
CCAGAAACCT TGGTCACCAT GAACTTGTCA TTCAACAAAT TTGCTGATTC TGTTTTTGGG 
TGCTTGCCTA GAAACATTCA AATACTGGAC CTGAATAGTA ACAAAATTCA AACTGTCCCT 
AAAGCGATTA CTCACCTGAC ATCTTTGCGA GAGTTAAATC TTGCATTTAA TTTTCTAACT 
GATCTTCCTG GGTGCAGTCA TTTCAGAAGA CTCTTAGTTC TGAACGTTGA AATGAACTTA 
ATTCTCAGCT CATCTCTGGA TTTTTTCCAG AGCTGCCAGG AAGTTAAAAC TCTAAATGCA 
GGAAGAAATC CATTCCGATG TACTTGTGAA TTAAGAGATT TCATTCAGCT TGGAAAATAC 
TCAGAAGGCA TGATGGTTGG ATGGTCAGAT TCATACATCT GTGAATACCC TTTGAATCTA 
AAGGGGACTC AGTTAAAGGA TGTTCATCTT CCAGAAATAT CTTGCAACAC AGGTTTGCTG 
ATTGTCACCA TTGTGGTTGT CATGCTCGTT CTGGGGATGG CTGTGGCCTT CTGCTGCCTC 
CACTTTGATT TGCCCTGGTA TCTCAGGATG CTGCATCAAT GGACTCAGAC ATGGCTCAGG 
GTTAGGAAGA CAACTCAGGA ACAACTCAAA AGAAGTGTCC AATTCCATGT GTTTATTTCA 
TACAGTGAAC ATGATTCTGC CTGGGTGAAG TATGAATTGA TTCCCAGTCT AGAGAAAGAA 
GATGGTTCTG TTCTGATTTG CCTTCATGAG GGAAACTCTG ACCCTGGCAA GAGCATGACT 
GAAGATACCA TAAACTGCAT TGAGAAAAGT TACAAGTCCA TCTTTGTTTT GTCTCCCAGC 
TTTGTCCAGA CTGAATGGTG CCATTATGAA CCCTACTTTG CCCACCACAA TCTCTTCCAT 
GAAAGTCTTG ATTACATAAT TCTTATCTTA CTGGAACCCA TTCCACTCTA CTGCATCCCT 
ACCAGATATC CTGAGCTGAA AGCTCTCATG GAAAAGAAAG CATACTTGGA ATGGCCCAAG 
GATAGGCGTA AATGTGGCCT TTTTTGGGCA AACCTTCGAG CTGCTCTTCA TGTTAATTTA 
TTAGACACCA GAGGGACATG TGAACTACAG ACATTCACAG AACTGAATGA AGGGTTTGGA 
GGTTCTGCAA TCTCTCTGAT CAGAACAGAC TGCCTGTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Sequence variability and protein domain architectures for bovine Toll-like receptors 1, 5, and 10.
Genomics90(4)502-15(2007 Oct)
Seabury CM,Cargill EJ,Womack JE

Genomic organization and transcript profiling of the bovine toll-like receptor gene cluster TLR6-TLR1-TLR10.
Gene38445-50(2006 Dec)
Opsal MA,V?ge DI,Hayes B,Berget I,Lien S

Expression of TOLL-like receptors (TLR) by bovine antigen-presenting cells-potential role in pathogen discrimination?
Veterinary immunology and immunopathology112(1-2)2-11(2006 Jul)
Werling D,Piercy J,Coffey TJ

Radiation hybrid mapping of all 10 characterized bovine Toll-like receptors.
Animal genetics37(1)47-50(2006 Feb)
McGuire K,Jones M,Werling D,Williams JL,Glass EJ,Jann O

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TLR10 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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