CDC42 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CDC42
Entrez Gene ID	532712
Full Name	cell division cycle 42
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001046332.1	NP_001039797.1	cell division control protein 42 homolog precursor

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	CDC42	XP_003951460.1
Canis lupus familiaris (dog)	CDC42	NP_001003254.1
Saccharomyces cerevisiae (baker's yeast)	CDC42	NP_013330.1
Neurospora crassa	NCU06454	XP_957345.2
Xenopus tropicalis (tropical clawed frog)	cdc42	NP_001017070.1
Homo sapiens (human)	CDC42	NP_001034891.1
Danio rerio (zebrafish)	cdc42l	NP_956159.1
Magnaporthe oryzae (rice blast fungus)	MGG_00466	XP_003718598.1
	LOC100424807	XP_002803768.1
Caenorhabditis elegans (roundworm)	cdc-42	NP_495598.1
Oryza sativa (rice)	Os01g0229400	NP_001042486.1
Anopheles gambiae (African malaria mosquito)	CDC42_ANOGA	XP_003436126.1
Kluyveromyces lactis	KLLA0A04213g	XP_451186.1
Eremothecium gossypii	AGOS_AGL093W	NP_986573.1
Bos taurus (cattle)	CDC42	NP_001039797.1
Gallus gallus (chicken)	CDC42	NP_990379.1
Drosophila melanogaster (fruit fly)	Cdc42	NP_001245764.1
Schizosaccharomyces pombe (fission yeast)	cdc42	NP_593536.1

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

The Mycobacterium avium subsp. paratuberculosis MAP3464 gene encodes an oxidoreductase involved in invasion of bovine epithelial cells through the activation of host cell Cdc42.
Alonso-Hearn M, Patel D, Danelishvili L, Meunier-Goddik L, Bermudez LE
Infection and immunity76(1)170-8(2008 Jan)

Prioritising guidance cues: directional migration induced by substratum contours and electrical gradients is controlled by a rho/cdc42 switch.
Rajnicek AM, Foubister LE, McCaig CD
Developmental biology312(1)448-60(2007 Dec)

Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.
Tzima E, Kiosses WB, del Pozo MA, Schwartz MA
The Journal of biological chemistry278(33)31020-3(2003 Aug)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study revealed a novel signaling pathway activated during M. avium subsp. paratuberculosis entry that links the product of MAP3464 gene to activation of Cdc42 in the host cell.
Title: The Mycobacterium avium subsp. paratuberculosis MAP3464 gene encodes an oxidoreductase involved in invasion of bovine epithelial cells through the activation of host cell Cdc42.

These data are consistent with the idea that migrating corneal epithelial cells use a cdc42/rho "switch" to sort vectoral cues, with cdc42 controlling electrotaxis and rho controlling contact guidance.
Title: Prioritising guidance cues: directional migration induced by substratum contours and electrical gradients is controlled by a rho/cdc42 switch.

shear-stimulated integrin dynamics induce polarized Cdc42 activity, which induces MTOC localization through the Par6-protein kinase Czeta complex.
Title: Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.

The following CDC42 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDC42 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa42626	NM_001046332.1 Latest version!	Bos taurus cell division cycle 42 (CDC42), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CDC42 ( NM_001046332.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001039797.1 Bos taurus cell division cycle 42 (CDC42), mRNA.

Price & Availability↑

CloneID	OBa42626
Clone ID Related Accession (Same CDS sequence)	NM_001046332.1
Accession Version	NM_001046332.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 576bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-18
Organism	Bos taurus(cattle)
Product	cell division control protein 42 homolog precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC105461.1. On Sep 7, 2006 this sequence version replaced XM_611868.2. ##Evidence-Data-START## Transcript exon combination :: BC105461.1 [ECO:0000332] RNAseq introns :: mixed/partial sample support SAMN04335739, SAMN04335740 [ECO:0000350] ##Evidence-Data-END##

ATGCAGACAA TTAAGTGCGT TGTTGTGGGT GATGGTGCCG TTGGTAAAAC ATGTCTCCTG 
ATATCCTACA CAACAAACAA ATTTCCATCT GAGTATGTAC CAACTGTTTT TGACAACTAT 
GCTGTCACAG TTATGATTGG TGGGGAGCCA TATACTCTTG GACTTTTTGA TACTGCAGGG 
CAAGAGGATT ATGACAGATT ACGACCGCTG AGTTATCCAC AAACAGATGT ATTTCTAGTC 
TGCTTTTCAG TGGTCTCTCC ATCCTCATTC GAAAATGTGA AAGAAAAGTG GGTGCCTGAG 
ATAACTCACC ACTGTCCAAA GACTCCTTTC TTGCTTGTTG GGACCCAAAT TGATCTCAGA 
GATGACCCCT CTACTATTGA GAAGCTTGCT AAGAATAAGC AGAAGCCTAT CACTCCAGAG 
ACTGCTGAAA AACTGGCCCG TGACCTGAAG GCTGTCAAGT ATGTGGAGTG CTCTGCACTC 
ACACAGAAAG GCCTAAAGAA TGTATTTGAT GAAGCAATAT TGGCTGCCCT GGAGCCTCCA 
GAACCGAAGA AGAGCCGCAG GTGTGTGCTG CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001039797.1
CDS	73..648
Translation	MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL

Target ORF information:

RefSeq Version	NM_001046332.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cell division cycle 42 (CDC42), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001046332.1

ORF Insert Sequence:

ATGCAGACAA TTAAGTGCGT TGTTGTGGGT GATGGTGCCG TTGGTAAAAC ATGTCTCCTG 
ATATCCTACA CAACAAACAA ATTTCCATCT GAGTATGTAC CAACTGTTTT TGACAACTAT 
GCTGTCACAG TTATGATTGG TGGGGAGCCA TATACTCTTG GACTTTTTGA TACTGCAGGG 
CAAGAGGATT ATGACAGATT ACGACCGCTG AGTTATCCAC AAACAGATGT ATTTCTAGTC 
TGCTTTTCAG TGGTCTCTCC ATCCTCATTC GAAAATGTGA AAGAAAAGTG GGTGCCTGAG 
ATAACTCACC ACTGTCCAAA GACTCCTTTC TTGCTTGTTG GGACCCAAAT TGATCTCAGA 
GATGACCCCT CTACTATTGA GAAGCTTGCT AAGAATAAGC AGAAGCCTAT CACTCCAGAG 
ACTGCTGAAA AACTGGCCCG TGACCTGAAG GCTGTCAAGT ATGTGGAGTG CTCTGCACTC 
ACACAGAAAG GCCTAAAGAA TGTATTTGAT GAAGCAATAT TGGCTGCCCT GGAGCCTCCA 
GAACCGAAGA AGAGCCGCAG GTGTGTGCTG CTATGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

The Mycobacterium avium subsp. paratuberculosis MAP3464 gene encodes an oxidoreductase involved in invasion of bovine epithelial cells through the activation of host cell Cdc42.
Infection and immunity76(1)170-8(2008 Jan)
Alonso-Hearn M,Patel D,Danelishvili L,Meunier-Goddik L,Bermudez LE

Prioritising guidance cues: directional migration induced by substratum contours and electrical gradients is controlled by a rho/cdc42 switch.
Developmental biology312(1)448-60(2007 Dec)
Rajnicek AM,Foubister LE,McCaig CD

Localized cdc42 activation, detected using a novel assay, mediates microtubule organizing center positioning in endothelial cells in response to fluid shear stress.
The Journal of biological chemistry278(33)31020-3(2003 Aug)
Tzima E,Kiosses WB,del Pozo MA,Schwartz MA

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CDC42 cDNA ORF clone, Bos taurus(cattle)

Gene

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gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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