KCNJ11 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	KCNJ11
Entrez Gene ID	532060
Full Name	potassium voltage-gated channel subfamily J member 11
General protein information	Preferred Names potassium voltage-gated channel subfamily J member 11 Names ATP-sensitive inward rectifier potassium channel 11 potassium inwardly-rectifying channel J11 potassium inwardly-rectifying channel, subfamily J, member 11
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001081598.1	NP_001075067.1	ATP-sensitive inward rectifier potassium channel 11

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	KCNJ11	XP_521849.2
Mus musculus (house mouse)	Kcnj11	NP_034732.1
Rattus norvegicus (Norway rat)	Kcnj11	NP_112648.2
Gallus gallus (chicken)	KCNJ11	XP_426402.4
Homo sapiens (human)	KCNJ11	NP_000516.3
Canis lupus familiaris (dog)	KCNJ11	XP_542519.2
Xenopus tropicalis (tropical clawed frog)	LOC100492679	XP_004916335.1
	KCNJ11	XP_001089155.1
Bos taurus (cattle)	KCNJ11	NP_001075067.1
Danio rerio (zebrafish)	kcnj11	NP_001034916.1

Gene Ontology
Bibliography

Related articles in PubMed

Allele- and parent-of-origin-specific effects on expression of the KCNJ11 gene: A candidate for meat tenderness in cattle.
de Souza MM, Niciura SC, Tizioto PC, Ibelli AM, Gasparin G, Rocha MI, Bressani FA, Malag?-Jr W, Diniz WJ, de Oliveira PS, Lima AO, Mudadu MA, Barioni Junior W, Coutinho LL, Regitano LC
Genetics and molecular research : GMR15(3)(2016 Aug)

Identification of KCNJ11 as a functional candidate gene for bovine meat tenderness.
Tizioto PC, Gasparin G, Souza MM, Mudadu MA, Coutinho LL, Mour?o GB, Tholon P, Meirelles SL, Tullio RR, Rosa AN, Alencar MM, Medeiros SR, Siqueira F, Feij? GL, Nassu RT, Regitano LC
Physiological genomics45(24)1215-21(2013 Dec)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

This study is the first to describe the differential allelic expression of bovine KCNJ11 responsible for meat tenderness.
Title: Allele- and parent-of-origin-specific effects on expression of the KCNJ11 gene: A candidate for meat tenderness in cattle.

effect of KCNJ11 observed on muscle is potentially due to changes in activity of KATP channels, which in turn influence the flow of potassium in the intracellular space, allowing establishment of the membrane potential necessary for muscle contraction
Title: Identification of KCNJ11 as a functional candidate gene for bovine meat tenderness.

The following KCNJ11 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the KCNJ11 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa02080	NM_001081598.1 Latest version!	Bos taurus potassium inwardly rectifying channel subfamily J member 11 (KCNJ11), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$258.30 $369.00

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

KCNJ11 ( NM_001081598.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001075067.1 Bos taurus potassium inwardly rectifying channel subfamily J member 11 (KCNJ11), mRNA.

Price & Availability↑

CloneID	OBa02080
Clone ID Related Accession (Same CDS sequence)	NM_001081598.1
Accession Version	NM_001081598.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 1167bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-07-30
Organism	Bos taurus(cattle)
Product	ATP-sensitive inward rectifier potassium channel 11
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from BC133379.1. On Feb 20, 2007 this sequence version replaced XM_610569.3. ##Evidence-Data-START## Transcript exon combination :: BC133379.1 [ECO:0000332] ##Evidence-Data-END##

ATGCTGTCCC GCAAGGGCAT CATCCCCGAG GAGTATGTGC TCACGCGACT AGCAGAGGAC 
CCCGCAGAGC CCCGGTACCG TGCCCGTGAG CGGAAAGCCC GCTTCGTGTC CAAGAACGGC 
AACTGCAACG TGGCCCACAA GAACATCCGG GAGCAAGGCC GCTTCCTACA GGACGTGTTC 
ACCACGCTGG TGGATCTCAA GTGGCCATAC ACGCTGCTCA TCTTCACCAT GTCCTTCCTG 
TGCAGCTGGC TGCTCTTTGC CATGGTCTGG TGGCTCATCG CCTTCGCCCA CGGTGACCTG 
GCCCCTGGCG AGGGTGCCGC TGTGCCCTGC GTCACCAGCA TCCACTCCTT TTCGTCTGCC 
TTCCTTTTCT CCATTGAGGT CCAGGTGACC ATTGGTTTCG GCGGGCGCAT GGTGACCGAG 
GAGTGCCCTC TGGCCATCCT GATCCTCATT GTGCAGAACA TCGTGGGGCT CATGATCAAC 
GCCATCATGC TGGGCTGCAT CTTCATGAAG ACGGCTCAGG CCCACCGGCG GGCCGAGACC 
CTCATCTTCA GCAAGCATGC GGTCATCGCC CTGCGCCACG GCCGCCTCTG CTTCATGCTG 
CGCGTGGGCG ACCTCCGGAA GAGCATGATC ATCAGTGCCA CCATCCACAT GCAGGTGGTG 
CGCAAGACCA CCAGCCCTGA GGGTGAGGTG GTCCCCCTCC ACCAGGTGGA CATCCCCATG 
GAGAATGGTG TGGGTGGCAA TAGCATCTTT CTGGTGGCTC CGCTCATCAT CTACCACGTC 
ATTGACGCCA ACAGCCCGCT CTATGACCTG GCGCCCTGCG ACCTGCACCA CCATCAGGAC 
CTTGAGATCA TCGTCATCCT GGAAGGTGTG GTGGAAACCA CGGGCATCAC CACCCAGGCC 
CGCACCTCCT ACCTGGCCGA CGAGATCTTG TGGGGCCAGC GCTTTGTACC CATTGTGGCC 
GAGGAGGATG GCCGCTACTC CGTGGACTAC TCCAAGTTTG GCAACACTAT CAAAGTGCCC 
ACGCCACTCT GCACAGCCCG CCAGCTTGAG GAGGACCCCA GCCTGCTGGA TGTCCTGACC 
CTTGTCCGCG GGCCCTTGCG CAAGCGCACC GTGGCTGTGG CCAAGGCCAA GCCCAAGTTC 
AGCATCTCTC CAGACTCCCT GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001075067.1
CDS	444..1610
Translation	MLSRKGIIPEEYVLTRLAEDPAEPRYRARERKARFVSKNGNCNVAHKNIREQGRFLQDVFTTLVDLKWPYTLLIFTMSFLCSWLLFAMVWWLIAFAHGDLAPGEGAAVPCVTSIHSFSSAFLFSIEVQVTIGFGGRMVTEECPLAILILIVQNIVGLMINAIMLGCIFMKTAQAHRRAETLIFSKHAVIALRHGRLCFMLRVGDLRKSMIISATIHMQVVRKTTSPEGEVVPLHQVDIPMENGVGGNSIFLVAPLIIYHVIDANSPLYDLAPCDLHHHQDLEIIVILEGVVETTGITTQARTSYLADEILWGQRFVPIVAEEDGRYSVDYSKFGNTIKVPTPLCTARQLEEDPSLLDVLTLVRGPLRKRTVAVAKAKPKFSISPDSLS

Target ORF information:

RefSeq Version	NM_001081598.1
Organism	Bos taurus(cattle)
Definition	Bos taurus potassium inwardly rectifying channel subfamily J member 11 (KCNJ11), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001081598.1

ORF Insert Sequence:

ATGCTGTCCC GCAAGGGCAT CATCCCCGAG GAGTATGTGC TCACGCGACT AGCAGAGGAC 
CCCGCAGAGC CCCGGTACCG TGCCCGTGAG CGGAAAGCCC GCTTCGTGTC CAAGAACGGC 
AACTGCAACG TGGCCCACAA GAACATCCGG GAGCAAGGCC GCTTCCTACA GGACGTGTTC 
ACCACGCTGG TGGATCTCAA GTGGCCATAC ACGCTGCTCA TCTTCACCAT GTCCTTCCTG 
TGCAGCTGGC TGCTCTTTGC CATGGTCTGG TGGCTCATCG CCTTCGCCCA CGGTGACCTG 
GCCCCTGGCG AGGGTGCCGC TGTGCCCTGC GTCACCAGCA TCCACTCCTT TTCGTCTGCC 
TTCCTTTTCT CCATTGAGGT CCAGGTGACC ATTGGTTTCG GCGGGCGCAT GGTGACCGAG 
GAGTGCCCTC TGGCCATCCT GATCCTCATT GTGCAGAACA TCGTGGGGCT CATGATCAAC 
GCCATCATGC TGGGCTGCAT CTTCATGAAG ACGGCTCAGG CCCACCGGCG GGCCGAGACC 
CTCATCTTCA GCAAGCATGC GGTCATCGCC CTGCGCCACG GCCGCCTCTG CTTCATGCTG 
CGCGTGGGCG ACCTCCGGAA GAGCATGATC ATCAGTGCCA CCATCCACAT GCAGGTGGTG 
CGCAAGACCA CCAGCCCTGA GGGTGAGGTG GTCCCCCTCC ACCAGGTGGA CATCCCCATG 
GAGAATGGTG TGGGTGGCAA TAGCATCTTT CTGGTGGCTC CGCTCATCAT CTACCACGTC 
ATTGACGCCA ACAGCCCGCT CTATGACCTG GCGCCCTGCG ACCTGCACCA CCATCAGGAC 
CTTGAGATCA TCGTCATCCT GGAAGGTGTG GTGGAAACCA CGGGCATCAC CACCCAGGCC 
CGCACCTCCT ACCTGGCCGA CGAGATCTTG TGGGGCCAGC GCTTTGTACC CATTGTGGCC 
GAGGAGGATG GCCGCTACTC CGTGGACTAC TCCAAGTTTG GCAACACTAT CAAAGTGCCC 
ACGCCACTCT GCACAGCCCG CCAGCTTGAG GAGGACCCCA GCCTGCTGGA TGTCCTGACC 
CTTGTCCGCG GGCCCTTGCG CAAGCGCACC GTGGCTGTGG CCAAGGCCAA GCCCAAGTTC 
AGCATCTCTC CAGACTCCCT GTCCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Allele- and parent-of-origin-specific effects on expression of the KCNJ11 gene: A candidate for meat tenderness in cattle.
Genetics and molecular research : GMR15(3)(2016 Aug)
de Souza MM,Niciura SC,Tizioto PC,Ibelli AM,Gasparin G,Rocha MI,Bressani FA,Malag?-Jr W,Diniz WJ,de Oliveira PS,Lima AO,Mudadu MA,Barioni Junior W,Coutinho LL,Regitano LC

Identification of KCNJ11 as a functional candidate gene for bovine meat tenderness.
Physiological genomics45(24)1215-21(2013 Dec)
Tizioto PC,Gasparin G,Souza MM,Mudadu MA,Coutinho LL,Mour?o GB,Tholon P,Meirelles SL,Tullio RR,Rosa AN,Alencar MM,Medeiros SR,Siqueira F,Feij? GL,Nassu RT,Regitano LC

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

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KCNJ11 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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