Gene Symbol | CRY2 |
Entrez Gene ID | 509058 |
Full Name | cryptochrome circadian regulator 2 |
General protein information |
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Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
Summary | This gene encodes a flavin adenine dinucleotide-binding protein that is a key component of the circadian core oscillator complex, which regulates the circadian clock. This gene is upregulated by CLOCK/ARNTL heterodimers but then represses this upregulation in a feedback loop using PER/CRY heterodimers to interact with CLOCK/ARNTL. Polymorphisms in this gene have been associated with altered sleep patterns. The encoded protein is widely conserved across plants and animals. [provided by RefSeq, Feb 2014]. |