CDH5 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CDH5
Entrez Gene ID	414735
Full Name	cadherin 5
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001001601.1	NP_001001601.1	cadherin-5 precursor
XM_024977976.1	XP_024833744.1	cadherin-5 isoform X1

Pathways from BioSystems

Homologies

Rattus norvegicus (Norway rat)	Cdh5	NP_001100877.1
Gallus gallus (chicken)	CDH5	NP_989558.1
	CDH5	XP_001082641.1
Pan troglodytes (chimpanzee)	CDH5	XP_523383.3
Canis lupus familiaris (dog)	CDH5	XP_546894.2
Homo sapiens (human)	CDH5	NP_001786.2
Bos taurus (cattle)	CDH5	NP_001001601.1
Mus musculus (house mouse)	Cdh5	NP_033998.2
Danio rerio (zebrafish)	cdh5	NP_001003983.1
Xenopus tropicalis (tropical clawed frog)	cdh5	XP_002933718.2

Gene Ontology
Bibliography

Related articles in PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Engineering amount of cell-cell contact demonstrates biphasic proliferative regulation through RhoA and the actin cytoskeleton.
Gray DS, Liu WF, Shen CJ, Bhadriraju K, Nelson CM, Chen CS
Experimental cell research314(15)2846-54(2008 Sep)

Cadherins, RhoA, and Rac1 are differentially required for stretch-mediated proliferation in endothelial versus smooth muscle cells.
Liu WF, Nelson CM, Tan JL, Chen CS
Circulation research101(5)e44-52(2007 Aug)

Hydrostatic pressure influences morphology and expression of VE-cadherin of vascular endothelial cells.
Ohashi T, Sugaya Y, Sakamoto N, Sato M
Journal of biomechanics40(11)2399-405(2007)

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin.
Gavard J, Gutkind JS
Nature cell biology8(11)1223-34(2006 Nov)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

In all, these results demonstrate that cell-cell contact signals through VE-cadherin, RhoA, and intracellular tension in the actin cytoskeleton to regulate proliferation.
Title: Engineering amount of cell-cell contact demonstrates biphasic proliferative regulation through RhoA and the actin cytoskeleton.

exposure of BAECs to hydrostatic pressure (PHYSIOLOGIC PRESSURE) may downregulate the expression of VE-cadherin, resulting in loss of contact inhibition followed by increased proliferation and formation of a multilayered structure
Title: Hydrostatic pressure influences morphology and expression of VE-cadherin of vascular endothelial cells.

results indicate that integrin engagement disrupts VE-cadherin-containing adherens junctions via the activation of Src, but not Ras, possibly as a result of modulation of the actin network
Title: Integrins regulate VE-cadherin and catenins: dependence of this regulation on Src, but not on Ras.

a VE-cadherin-dependent pathway may link T2-TrpRS to inhibition of new blood vessel formation
Title: VE-cadherin links tRNA synthetase cytokine to anti-angiogenic function.

Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA
Title: Vascular endothelial-cadherin regulates cytoskeletal tension, cell spreading, and focal adhesions by stimulating RhoA.

The following CDH5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDH5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa43878	NM_001001601.1 Latest version!	Bos taurus cadherin 5 (CDH5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00
OBa224822	XM_024977976.1 Latest version!	Bos taurus cadherin 5 (CDH5), transcript variant X1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	14-16	$391.30 $559.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CDH5 ( NM_001001601.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001001601.1 Bos taurus cadherin 5 (CDH5), mRNA.

Price & Availability↑

CloneID	OBa43878
Clone ID Related Accession (Same CDS sequence)	NM_001001601.1
Accession Version	NM_001001601.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2352bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Bos taurus(cattle)
Product	cadherin-5 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY363224.1. ##Evidence-Data-START## Transcript exon combination :: AY363224.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END##

ATGCAGGCAC TCGTGATGCT GCTGGCCACG GGGGCCACCT ACTACCTGGG CCTGCTGGCA 
GCAGCTGCAG CAGCCGTCAA CCCTGGCCGA CCCAACACCC CCGGCTCGCT GCCCGCTCAC 
CGGCGCCAGA AGAGAGACTG GATCTGGAAT CAGATGCACA TCGACGAAGA GAGAAATGAC 
TCGCTGCCCC ATTACGTGGG CAAGATTAAA TCGAGTGTGG ACCCCAAGAA GACCGAGTAC 
CAGCTCAGAG GAGAGTCTGC CGGCAAGGTG TTCCGGGTCG ACAAGAACAC AGGCGATGTG 
TACGCCTTAG AGAGGCTGGA CAGGGAGAAG ATCTCCGAGT ACCACCTCAC TGCCCTTGTG 
GTGGACAAGG ACTCCAAGAA GAACCTGGAG TCTCCTTCTA GCTTCACCAT CAAAGTTCAC 
GATGTCAACG ATAACTGGCC TGTGTTTACC CACCGGGTGT TCAATGCCTC TGTGCCCGAG 
ATGTCAGGGA TAGGGACCTC GGTTATCCAG GTGACAGCGA TGGATGCAGA TGACCCCACG 
GTGGCAGACC ATGCTTCTGT CGTGTACCAG CTCACAAAGG GAAAAGAAAA TTTCGACATC 
CGTGGTTCTG GACTCATTGT CACCATGAAC AAACACCTGG ACCGAGAGAC GCAGGACAAG 
TACGAGGTTG TGGTGAAAGC AGAAGATGCC CAGGGCCGCA GGGGGGAGTC AGGCACAGCC 
ACTGTGTTCA TCACGCTGCA GGACGTCAAC GACAACTTCC CCATCTTCAC CCAGAACAGG 
TATACATTTT CTGTGCCAGA AGACATCCGT GTGGGCAGCC CCCTGGGCTC TCTGTTTGTT 
GAGGACCCAG ACGAGCCCCA AAACCGGAAG ACCAAGTACA GCTTCGTGCA GGGAGAGTAC 
AGGGACACCT TCACCATCGA TACGGACCCC AGCCACAACG AGGGCATCAT CAAGCCCATA 
AAGCCCCTGG ACTATGAACG CATCCGGCAA TACAGCTTCA CCATCGAGGC CACAGACCCC 
ACCATTGACC TCCGCTACCT GGGCAGCACC TCCCCCAAGA ACATCGCCCG TGTCATTATC 
AACGTCACAG ACGTGGATGA GCCCCCCATC TTCCAGCAAC CTTTTTACCA CTTCCAGCTG 
CAGGAGAACC AGAAGAAGCC TCTGATTGGC TCAGTGCTGG CCAAGGACCC TGATGCTGCT 
CAGCGGGACA TCAGGTACTC CATCCGCAGG ACCAGTGACA AGGGCCAGTT CTTCGGAATA 
ACCAAGAAAG GGGGCATTTA CAACGACAAA GAACTGGACA GAGAAGTGTA CCCTTGGTAC 
AACCTGACAG TGGAGGCCAA AGAGGTGGAT CTGAGTGGGA CTCCCACGGG CAAAGAATCC 
ATTGTGCAGG TCCACATTGA AGTTATGGAT GAGAATGACA ATGCCCCAGA GTTCGCCAAG 
CCTTATGAGC CCAAAGTGTG TGAGAACGCC CCCCAGGGCA AGCTGGTCGT GCAAATCTCG 
GCAACAGACA AGGATATAAC ACCACGAGAC GTGAAGTTCA AGTTCTCCCT GAGCACTGAG 
GACAGCAACT TCACCCTCAT TGATAATCAC GATAACACGG CCAACATCAT AGTCAAGTAC 
GGGTATTTTG ACCGGGAGCG CGCCAAGGTC CACCACCTGC CCGTGCTCAT CTCGGACAAC 
GGGAGGCCAA GCCTCACGGG CACCAGCACG CTGCACGTGA CCGTGTGCAA GTGCAACGAG 
CACGGCGAGT TCACCCTGTG CGAGGAGGCG GCCGCCCAGG TGGGCATCAG CATCCAGGCG 
CTCGTCGCCA TTTTCCTCTG CATCCTCACC TTCACAGTGA TCACCCTCCT CATCATTCTG 
CGGAGGCGGC TCCGGAAGCA GGCCCGCGCC CATGGCAAGA GCGTGCCGGA GATCCACGAG 
CAGCTGGTCA CCTACGATGA GGAGGGCGGT GGCGAGATGG ACACCACCAG CTACGACGTG 
TCAGTGCTCA ACTCTGCGCG CCATGGCGGG GCCAAGCCCC CACGCCCGGC CCTGGACGCG 
CGGCCGTCTC TTTACGCTCA GGTGCAGAAG CCACCCCGGC AAGCGCCCGG GGCGCATGCA 
CCCGGGGAGA TGGCCGCCAT GATCGGGGTG AAGAAGGACG AGGCGGACCA CGACGGCGGC 
GGCCCACCCT ATGACACGCT GCACATCTAT GGCTACGAGG GCGCCGAGTC CATTGCCGAG 
TCCCTCAGCT CCCTGGGCAC GGATTCATCG GACTCGGACA TTGATTACGA CTTTCTCAAT 
GACTGGGGAA CGAGGTTCAA GATGCTGGCC GAGCTGTATG GCTCAGACCC CCAGGAGGAG 
CTGGTGTATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001001601.1
CDS	58..2409
Translation	MQALVMLLATGATYYLGLLAAAAAAVNPGRPNTPGSLPAHRRQKRDWIWNQMHIDEERNDSLPHYVGKIKSSVDPKKTEYQLRGESAGKVFRVDKNTGDVYALERLDREKISEYHLTALVVDKDSKKNLESPSSFTIKVHDVNDNWPVFTHRVFNASVPEMSGIGTSVIQVTAMDADDPTVADHASVVYQLTKGKENFDIRGSGLIVTMNKHLDRETQDKYEVVVKAEDAQGRRGESGTATVFITLQDVNDNFPIFTQNRYTFSVPEDIRVGSPLGSLFVEDPDEPQNRKTKYSFVQGEYRDTFTIDTDPSHNEGIIKPIKPLDYERIRQYSFTIEATDPTIDLRYLGSTSPKNIARVIINVTDVDEPPIFQQPFYHFQLQENQKKPLIGSVLAKDPDAAQRDIRYSIRRTSDKGQFFGITKKGGIYNDKELDREVYPWYNLTVEAKEVDLSGTPTGKESIVQVHIEVMDENDNAPEFAKPYEPKVCENAPQGKLVVQISATDKDITPRDVKFKFSLSTEDSNFTLIDNHDNTANIIVKYGYFDRERAKVHHLPVLISDNGRPSLTGTSTLHVTVCKCNEHGEFTLCEEAAAQVGISIQALVAIFLCILTFTVITLLIILRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSARHGGAKPPRPALDARPSLYAQVQKPPRQAPGAHAPGEMAAMIGVKKDEADHDGGGPPYDTLHIYGYEGAESIAESLSSLGTDSSDSDIDYDFLNDWGTRFKMLAELYGSDPQEELVY

Target ORF information:

RefSeq Version	NM_001001601.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cadherin 5 (CDH5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001001601.1

ORF Insert Sequence:

ATGCAGGCAC TCGTGATGCT GCTGGCCACG GGGGCCACCT ACTACCTGGG CCTGCTGGCA 
GCAGCTGCAG CAGCCGTCAA CCCTGGCCGA CCCAACACCC CCGGCTCGCT GCCCGCTCAC 
CGGCGCCAGA AGAGAGACTG GATCTGGAAT CAGATGCACA TCGACGAAGA GAGAAATGAC 
TCGCTGCCCC ATTACGTGGG CAAGATTAAA TCGAGTGTGG ACCCCAAGAA GACCGAGTAC 
CAGCTCAGAG GAGAGTCTGC CGGCAAGGTG TTCCGGGTCG ACAAGAACAC AGGCGATGTG 
TACGCCTTAG AGAGGCTGGA CAGGGAGAAG ATCTCCGAGT ACCACCTCAC TGCCCTTGTG 
GTGGACAAGG ACTCCAAGAA GAACCTGGAG TCTCCTTCTA GCTTCACCAT CAAAGTTCAC 
GATGTCAACG ATAACTGGCC TGTGTTTACC CACCGGGTGT TCAATGCCTC TGTGCCCGAG 
ATGTCAGGGA TAGGGACCTC GGTTATCCAG GTGACAGCGA TGGATGCAGA TGACCCCACG 
GTGGCAGACC ATGCTTCTGT CGTGTACCAG CTCACAAAGG GAAAAGAAAA TTTCGACATC 
CGTGGTTCTG GACTCATTGT CACCATGAAC AAACACCTGG ACCGAGAGAC GCAGGACAAG 
TACGAGGTTG TGGTGAAAGC AGAAGATGCC CAGGGCCGCA GGGGGGAGTC AGGCACAGCC 
ACTGTGTTCA TCACGCTGCA GGACGTCAAC GACAACTTCC CCATCTTCAC CCAGAACAGG 
TATACATTTT CTGTGCCAGA AGACATCCGT GTGGGCAGCC CCCTGGGCTC TCTGTTTGTT 
GAGGACCCAG ACGAGCCCCA AAACCGGAAG ACCAAGTACA GCTTCGTGCA GGGAGAGTAC 
AGGGACACCT TCACCATCGA TACGGACCCC AGCCACAACG AGGGCATCAT CAAGCCCATA 
AAGCCCCTGG ACTATGAACG CATCCGGCAA TACAGCTTCA CCATCGAGGC CACAGACCCC 
ACCATTGACC TCCGCTACCT GGGCAGCACC TCCCCCAAGA ACATCGCCCG TGTCATTATC 
AACGTCACAG ACGTGGATGA GCCCCCCATC TTCCAGCAAC CTTTTTACCA CTTCCAGCTG 
CAGGAGAACC AGAAGAAGCC TCTGATTGGC TCAGTGCTGG CCAAGGACCC TGATGCTGCT 
CAGCGGGACA TCAGGTACTC CATCCGCAGG ACCAGTGACA AGGGCCAGTT CTTCGGAATA 
ACCAAGAAAG GGGGCATTTA CAACGACAAA GAACTGGACA GAGAAGTGTA CCCTTGGTAC 
AACCTGACAG TGGAGGCCAA AGAGGTGGAT CTGAGTGGGA CTCCCACGGG CAAAGAATCC 
ATTGTGCAGG TCCACATTGA AGTTATGGAT GAGAATGACA ATGCCCCAGA GTTCGCCAAG 
CCTTATGAGC CCAAAGTGTG TGAGAACGCC CCCCAGGGCA AGCTGGTCGT GCAAATCTCG 
GCAACAGACA AGGATATAAC ACCACGAGAC GTGAAGTTCA AGTTCTCCCT GAGCACTGAG 
GACAGCAACT TCACCCTCAT TGATAATCAC GATAACACGG CCAACATCAT AGTCAAGTAC 
GGGTATTTTG ACCGGGAGCG CGCCAAGGTC CACCACCTGC CCGTGCTCAT CTCGGACAAC 
GGGAGGCCAA GCCTCACGGG CACCAGCACG CTGCACGTGA CCGTGTGCAA GTGCAACGAG 
CACGGCGAGT TCACCCTGTG CGAGGAGGCG GCCGCCCAGG TGGGCATCAG CATCCAGGCG 
CTCGTCGCCA TTTTCCTCTG CATCCTCACC TTCACAGTGA TCACCCTCCT CATCATTCTG 
CGGAGGCGGC TCCGGAAGCA GGCCCGCGCC CATGGCAAGA GCGTGCCGGA GATCCACGAG 
CAGCTGGTCA CCTACGATGA GGAGGGCGGT GGCGAGATGG ACACCACCAG CTACGACGTG 
TCAGTGCTCA ACTCTGCGCG CCATGGCGGG GCCAAGCCCC CACGCCCGGC CCTGGACGCG 
CGGCCGTCTC TTTACGCTCA GGTGCAGAAG CCACCCCGGC AAGCGCCCGG GGCGCATGCA 
CCCGGGGAGA TGGCCGCCAT GATCGGGGTG AAGAAGGACG AGGCGGACCA CGACGGCGGC 
GGCCCACCCT ATGACACGCT GCACATCTAT GGCTACGAGG GCGCCGAGTC CATTGCCGAG 
TCCCTCAGCT CCCTGGGCAC GGATTCATCG GACTCGGACA TTGATTACGA CTTTCTCAAT 
GACTGGGGAA CGAGGTTCAA GATGCTGGCC GAGCTGTATG GCTCAGACCC CCAGGAGGAG 
CTGGTGTATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

CDH5 ( XM_024977976.1 ) cDNA ORF clone, Bos taurus(cattle) -> XP_024833744.1 Bos taurus cadherin 5 (CDH5), transcript variant X1, mRNA.

Price & Availability↑

CloneID	OBa224822
Clone ID Related Accession (Same CDS sequence)	XM_024977976.1
Accession Version	XM_024977976.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2352bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2018-05-06
Organism	Bos taurus(cattle)
Product	cadherin-5 isoform X1
Comment	Comment: MODEL REFSEQ: This record is predicted by automated computational analysis. This record is derived from a genomic sequence (NC_037345.1) annotated using gene prediction method: Gnomon, supported by EST evidence. Also see: Documentation of NCBI's Annotation Process ##Genome-Annotation-Data-START## Annotation Provider :: NCBI Annotation Status :: Full annotation Annotation Name :: Bos taurus Annotation Release 106 Annotation Version :: 106 Annotation Pipeline :: NCBI eukaryotic genome annotation pipeline Annotation Software Version :: 8.0 Annotation Method :: Best-placed RefSeq; Gnomon Features Annotated :: Gene; mRNA; CDS; ncRNA ##Genome-Annotation-Data-END##

ATGCAGGCAC TCGTGATGCT GCTGGCCACG GGGGCCACCT ACTACCTGGG CCTGCTGGCA 
GCAGCTGCAG CAGCCGTCAA CCCTGGCCGA CCCAACACCC CCGGCTCGCT GCCCGCTCAC 
CGGCGCCAGA AGAGAGACTG GATCTGGAAT CAGATGCACA TCGACGAAGA GAGAAATGAC 
TCGCTGCCCC ATTACGTGGG CAAGATTAAA TCGAGTGTGG ACCCCAAGAA GACCGAGTAC 
CAGCTCAGAG GAGAGTCTGC CGGCAAGGTG TTCCGGGTCG ACAAGAACAC AGGCGATGTG 
TATGCCTTAG AGAGGCTGGA CAGGGAGAAG ATCTCCGAGT ACCACCTCAC TGCCCTTGTG 
GTGGACAAGG ACTCCAAGAA GAACCTGGAG TCTCCTTCTA GCTTCACCAT CAAAGTTCAC 
GATGTCAACG ATAACTGGCC TGTGTTTACC CACCGGGTGT TCAATGCCTC TGTGCCCGAG 
ATGTCAGGGA TAGGGACCTC GGTTATCCAG GTGACAGCGA TGGATGCAGA TGACCCCACG 
GTGGCAGACC ATGCTTCTGT CGTGTACCAG CTCACAAAGG GAAAAGAAAA TTTCGACATC 
CGTGGTTCTG GACTCATTGT CACCATGAAC AAACACCTGG ACCGAGAGAC GCAGGACAAG 
TACGAGGTTG TGGTGAAAGC AGAAGATGCC CAGGGCCGCA GGGGGGAGTC AGGCACAGCC 
ACTGTGTTCA TCACGCTGCA GGACGTCAAC GACAACTTCC CCATCTTCAC CCAGAACAGG 
TATACATTTT CTGTGCCAGA AGACATCCGT GTGGGCAGCC CCCTGGGCTC TCTGTTTGTT 
GAGGACCCAG ACGAGCCCCA AAACCGGAAG ACCAAGTACA GCTTCGTGCA GGGAGAGTAC 
AGGGACACCT TCACCATCGA TACGGACCCC AGCCACAACG AGGGCATCAT CAAGCCCATA 
AAGCCCCTGG ACTATGAACG CATCCGGCAA TACAGCTTCA CCATCGAGGC CACAGACCCC 
ACCATTGACC TCCGCTACCT GGGCAGCACC TCCCCCAAGA ACATCGCCCG TGTCATTATC 
AACGTCACAG ACGTGGATGA GCCCCCCATC TTCCAGCAAC CTTTTTACCA CTTCCAGCTG 
CAGGAGAACC AGAAGAAGCC TCTGATTGGC TCAGTGCTGG CCAAGGACCC TGATGCTGCT 
CAGCGGGACA TCAGGTACTC CATCCGCAGG ACCAGTGACA AGGGCCAGTT CTTCGGAATA 
ACCAAGAAAG GGGGCATTTA CAACGACAAA GAACTGGACA GAGAAGTGTA CCCTTGGTAC 
AACCTGACAG TGGAGGCCAA AGAGGTGGAT CTGAGTGGGA CTCCCACGGG CAAAGAATCC 
ATTGTGCAGG TCCACATTGA AGTTATGGAT GAGAATGACA ATGCCCCAGA GTTCGCCAAG 
CCTTATGAGC CCAAAGTGTG TGAGAACGCC CCCCAGGGCA AGCTGGTCGT GCAAATCTCG 
GCAACAGACA AGGATATAAC ACCACGAGAC GTGAAGTTCA AGTTCTCCCT GAGCACTGAG 
GACAGCAACT TCACCCTCAT TGATAATCAC GATAACACGG CCAACATCAT AGTCAAGTAC 
GGGTATTTTG ACCGGGAGCG CGCCAAGGTC CACCACCTGC CCGTGCTCAT CTCGGACAAC 
GGGAGGCCAA GCCTCACGGG CACCAGCACG CTGCACGTGA CCGTGTGCAA GTGCAACGAG 
CACGGCGAGT TCACCCTGTG CGAGGAGGCG GCCGCCCAGG TGGGCATCAG CATCCAGGCG 
CTCGTCGCCA TTTTCCTCTG CATCCTCACC TTCACAGTGA TCACCCTCCT CATCATTCTG 
CGGAGGCGGC TCCGGAAGCA GGCCCGCGCC CATGGCAAGA GCGTGCCGGA GATCCACGAG 
CAGCTGGTCA CCTACGATGA GGAGGGCGGT GGCGAGATGG ACACCACCAG CTACGACGTG 
TCAGTGCTCA ACTCTGCGCG CCATGGCGGG GCCAAGCCCC CACGCCCGGC CCTGGACGCG 
CGGCCGTCTC TTTACGCTCA GGTGCAGAAG CCACCCCGGC AAGCGCCCGG GGCGCATGCA 
CCCGGGGAGA TGGCCGCCAT GATCGGGGTG AAGAAGGACG AGGCGGACCA CGACGGCGGC 
GGCCCACCCT ATGACACGCT GCACATCTAT GGCTACGAGG GCGCCGAGTC CATTGCCGAG 
TCCCTCAGCT CCCTGGGCAC GGATTCATCG GACTCGGACA TTGATTACGA CTTTCTCAAT 
GACTGGGGAC CGAGGTTCAA GATGCTGGCC GAGCTGTATG GCTCAGACCC CCAGGAGGAG 
CTGGTGTATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	XP_024833744.1
CDS	163..2514
Translation	MQALVMLLATGATYYLGLLAAAAAAVNPGRPNTPGSLPAHRRQKRDWIWNQMHIDEERNDSLPHYVGKIKSSVDPKKTEYQLRGESAGKVFRVDKNTGDVYALERLDREKISEYHLTALVVDKDSKKNLESPSSFTIKVHDVNDNWPVFTHRVFNASVPEMSGIGTSVIQVTAMDADDPTVADHASVVYQLTKGKENFDIRGSGLIVTMNKHLDRETQDKYEVVVKAEDAQGRRGESGTATVFITLQDVNDNFPIFTQNRYTFSVPEDIRVGSPLGSLFVEDPDEPQNRKTKYSFVQGEYRDTFTIDTDPSHNEGIIKPIKPLDYERIRQYSFTIEATDPTIDLRYLGSTSPKNIARVIINVTDVDEPPIFQQPFYHFQLQENQKKPLIGSVLAKDPDAAQRDIRYSIRRTSDKGQFFGITKKGGIYNDKELDREVYPWYNLTVEAKEVDLSGTPTGKESIVQVHIEVMDENDNAPEFAKPYEPKVCENAPQGKLVVQISATDKDITPRDVKFKFSLSTEDSNFTLIDNHDNTANIIVKYGYFDRERAKVHHLPVLISDNGRPSLTGTSTLHVTVCKCNEHGEFTLCEEAAAQVGISIQALVAIFLCILTFTVITLLIILRRRLRKQARAHGKSVPEIHEQLVTYDEEGGGEMDTTSYDVSVLNSARHGGAKPPRPALDARPSLYAQVQKPPRQAPGAHAPGEMAAMIGVKKDEADHDGGGPPYDTLHIYGYEGAESIAESLSSLGTDSSDSDIDYDFLNDWGPRFKMLAELYGSDPQEELVY

Target ORF information:

RefSeq Version	XM_024977976.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cadherin 5 (CDH5), transcript variant X1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

XM_024977976.1

ORF Insert Sequence:

ATGCAGGCAC TCGTGATGCT GCTGGCCACG GGGGCCACCT ACTACCTGGG CCTGCTGGCA 
GCAGCTGCAG CAGCCGTCAA CCCTGGCCGA CCCAACACCC CCGGCTCGCT GCCCGCTCAC 
CGGCGCCAGA AGAGAGACTG GATCTGGAAT CAGATGCACA TCGACGAAGA GAGAAATGAC 
TCGCTGCCCC ATTACGTGGG CAAGATTAAA TCGAGTGTGG ACCCCAAGAA GACCGAGTAC 
CAGCTCAGAG GAGAGTCTGC CGGCAAGGTG TTCCGGGTCG ACAAGAACAC AGGCGATGTG 
TATGCCTTAG AGAGGCTGGA CAGGGAGAAG ATCTCCGAGT ACCACCTCAC TGCCCTTGTG 
GTGGACAAGG ACTCCAAGAA GAACCTGGAG TCTCCTTCTA GCTTCACCAT CAAAGTTCAC 
GATGTCAACG ATAACTGGCC TGTGTTTACC CACCGGGTGT TCAATGCCTC TGTGCCCGAG 
ATGTCAGGGA TAGGGACCTC GGTTATCCAG GTGACAGCGA TGGATGCAGA TGACCCCACG 
GTGGCAGACC ATGCTTCTGT CGTGTACCAG CTCACAAAGG GAAAAGAAAA TTTCGACATC 
CGTGGTTCTG GACTCATTGT CACCATGAAC AAACACCTGG ACCGAGAGAC GCAGGACAAG 
TACGAGGTTG TGGTGAAAGC AGAAGATGCC CAGGGCCGCA GGGGGGAGTC AGGCACAGCC 
ACTGTGTTCA TCACGCTGCA GGACGTCAAC GACAACTTCC CCATCTTCAC CCAGAACAGG 
TATACATTTT CTGTGCCAGA AGACATCCGT GTGGGCAGCC CCCTGGGCTC TCTGTTTGTT 
GAGGACCCAG ACGAGCCCCA AAACCGGAAG ACCAAGTACA GCTTCGTGCA GGGAGAGTAC 
AGGGACACCT TCACCATCGA TACGGACCCC AGCCACAACG AGGGCATCAT CAAGCCCATA 
AAGCCCCTGG ACTATGAACG CATCCGGCAA TACAGCTTCA CCATCGAGGC CACAGACCCC 
ACCATTGACC TCCGCTACCT GGGCAGCACC TCCCCCAAGA ACATCGCCCG TGTCATTATC 
AACGTCACAG ACGTGGATGA GCCCCCCATC TTCCAGCAAC CTTTTTACCA CTTCCAGCTG 
CAGGAGAACC AGAAGAAGCC TCTGATTGGC TCAGTGCTGG CCAAGGACCC TGATGCTGCT 
CAGCGGGACA TCAGGTACTC CATCCGCAGG ACCAGTGACA AGGGCCAGTT CTTCGGAATA 
ACCAAGAAAG GGGGCATTTA CAACGACAAA GAACTGGACA GAGAAGTGTA CCCTTGGTAC 
AACCTGACAG TGGAGGCCAA AGAGGTGGAT CTGAGTGGGA CTCCCACGGG CAAAGAATCC 
ATTGTGCAGG TCCACATTGA AGTTATGGAT GAGAATGACA ATGCCCCAGA GTTCGCCAAG 
CCTTATGAGC CCAAAGTGTG TGAGAACGCC CCCCAGGGCA AGCTGGTCGT GCAAATCTCG 
GCAACAGACA AGGATATAAC ACCACGAGAC GTGAAGTTCA AGTTCTCCCT GAGCACTGAG 
GACAGCAACT TCACCCTCAT TGATAATCAC GATAACACGG CCAACATCAT AGTCAAGTAC 
GGGTATTTTG ACCGGGAGCG CGCCAAGGTC CACCACCTGC CCGTGCTCAT CTCGGACAAC 
GGGAGGCCAA GCCTCACGGG CACCAGCACG CTGCACGTGA CCGTGTGCAA GTGCAACGAG 
CACGGCGAGT TCACCCTGTG CGAGGAGGCG GCCGCCCAGG TGGGCATCAG CATCCAGGCG 
CTCGTCGCCA TTTTCCTCTG CATCCTCACC TTCACAGTGA TCACCCTCCT CATCATTCTG 
CGGAGGCGGC TCCGGAAGCA GGCCCGCGCC CATGGCAAGA GCGTGCCGGA GATCCACGAG 
CAGCTGGTCA CCTACGATGA GGAGGGCGGT GGCGAGATGG ACACCACCAG CTACGACGTG 
TCAGTGCTCA ACTCTGCGCG CCATGGCGGG GCCAAGCCCC CACGCCCGGC CCTGGACGCG 
CGGCCGTCTC TTTACGCTCA GGTGCAGAAG CCACCCCGGC AAGCGCCCGG GGCGCATGCA 
CCCGGGGAGA TGGCCGCCAT GATCGGGGTG AAGAAGGACG AGGCGGACCA CGACGGCGGC 
GGCCCACCCT ATGACACGCT GCACATCTAT GGCTACGAGG GCGCCGAGTC CATTGCCGAG 
TCCCTCAGCT CCCTGGGCAC GGATTCATCG GACTCGGACA TTGATTACGA CTTTCTCAAT 
GACTGGGGAC CGAGGTTCAA GATGCTGGCC GAGCTGTATG GCTCAGACCC CCAGGAGGAG 
CTGGTGTATT AG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Engineering amount of cell-cell contact demonstrates biphasic proliferative regulation through RhoA and the actin cytoskeleton.
Experimental cell research314(15)2846-54(2008 Sep)
Gray DS,Liu WF,Shen CJ,Bhadriraju K,Nelson CM,Chen CS

Cadherins, RhoA, and Rac1 are differentially required for stretch-mediated proliferation in endothelial versus smooth muscle cells.
Circulation research101(5)e44-52(2007 Aug)
Liu WF,Nelson CM,Tan JL,Chen CS

Hydrostatic pressure influences morphology and expression of VE-cadherin of vascular endothelial cells.
Journal of biomechanics40(11)2399-405(2007)
Ohashi T,Sugaya Y,Sakamoto N,Sato M

VEGF controls endothelial-cell permeability by promoting the beta-arrestin-dependent endocytosis of VE-cadherin.
Nature cell biology8(11)1223-34(2006 Nov)
Gavard J,Gutkind JS

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CDH5 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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