CCL5 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CCL5
Entrez Gene ID	327712
Full Name	C-C motif chemokine ligand 5
Synonyms	RANTES
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_175827.2	NP_787021.1	C-C motif chemokine 5 precursor

Pathways from BioSystems

Homologies

	CCL5	NP_001028022.1
Homo sapiens (human)	CCL5	NP_002976.2
Gallus gallus (chicken)	CCL5	NP_001039297.1
Bos taurus (cattle)	CCL5	NP_787021.1
Pan troglodytes (chimpanzee)	CCL5	XP_001155572.3
Canis lupus familiaris (dog)	CCL5	NP_001003010.1
Mus musculus (house mouse)	Ccl5	NP_038681.2
Rattus norvegicus (Norway rat)	Ccl5	NP_112378.2

Gene Ontology
Bibliography

Related articles in PubMed

Live and inactivated Salmonella enterica serovar Typhimurium stimulate similar but distinct transcriptome profiles in bovine macrophages and dendritic cells.
Jensen K, Gallagher IJ, Kaliszewska A, Zhang C, Abejide O, Gallagher MP, Werling D, Glass EJ
Veterinary research4746(2016 Mar)

The chemokine CCL5 induces selective migration of bovine classical monocytes and drives their differentiation into LPS-hyporesponsive macrophages in vitro.
Hussen J, Frank C, D?vel A, Koy M, Schuberth HJ
Developmental and comparative immunology47(2)169-77(2014 Dec)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Decreasing sensitivity to RANTES (regulated on activation, normally T cell-expressed and -secreted) neutralization of CC chemokine receptor 5-using, non-syncytium-inducing virus variants in the course of human immunodeficiency virus type 1 infection.
Koning FA, Kwa D, Boeser-Nunnink B, Dekker J, Vingerhoed J, Hiemstra H, Schuitemaker H
The Journal of infectious diseases188(6)864-72(2003 Sep)

Cloning of bovine RANTES mRNA and its expression and regulation in ovaries in the periovulatory period.
Aust G, Brylla E, Lehmann I, Kiessling S, Spanel-Borowski K
FEBS letters463(1-2)160-4(1999 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

CCL5 but not CCL2 mainly attract bovine classical monocytes and promote their differentiation into LPS-hypo-responsive macrophages.
Title: The chemokine CCL5 induces selective migration of bovine classical monocytes and drives their differentiation into LPS-hyporesponsive macrophages in vitro.

decrease in sensitivity of HIV variants to RANTES neutralization during the course of progressive infection, but not during follow-up of long term survivors; data suggest a role for RANTES neutralization sensitivity of HIV-1 in AIDS pathogenesis
Title: Decreasing sensitivity to RANTES (regulated on activation, normally T cell-expressed and -secreted) neutralization of CC chemokine receptor 5-using, non-syncytium-inducing virus variants in the course of human immunodeficiency virus type 1 infection.

The following CCL5 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CCL5 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41267	NM_175827.2 Latest version!	Bos taurus C-C motif chemokine ligand 5 (CCL5), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CCL5 ( NM_175827.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_787021.1 Bos taurus C-C motif chemokine ligand 5 (CCL5), mRNA.

Price & Availability↑

CloneID	OBa41267
Clone ID Related Accession (Same CDS sequence)	NM_175827.2
Accession Version	NM_175827.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 276bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-10-17
Organism	Bos taurus(cattle)
Product	C-C motif chemokine 5 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AJ007043.2. On Jun 3, 2003 this sequence version replaced NM_175827.1. ##Evidence-Data-START## Transcript exon combination :: AJ007043.2, EH200635.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END##

ATGAAGGTCT CTGCCACTGC CTTCGCTGTC CTCCTGATGG CGGCCGCCCT CTGCGCTCCT 
GCTTCTGCCT CCCCATATGC CTCGGACACC ACGCCCTGCT GCTTTGCCTA TATCTCCCGC 
CCGCTGCCCC GCACCCACGT CCAGGAGTAT TTCTACACCA GCAGCAAGTG CTCCATGGCA 
GCAGTTGTCT TTATCACCAG GAAGAAGCGC CAGGTGTGCG CCAACCCAGA GAAGAAGTGG 
GTGCGAGAGT ACATCAACGC TTTGGAGTTG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_787021.1
CDS	55..330
Translation	MKVSATAFAVLLMAAALCAPASASPYASDTTPCCFAYISRPLPRTHVQEYFYTSSKCSMAAVVFITRKKRQVCANPEKKWVREYINALELS

Target ORF information:

RefSeq Version	NM_175827.2
Organism	Bos taurus(cattle)
Definition	Bos taurus C-C motif chemokine ligand 5 (CCL5), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_175827.2

ORF Insert Sequence:

ATGAAGGTCT CTGCCACTGC CTTCGCTGTC CTCCTGATGG CGGCCGCCCT CTGCGCTCCT 
GCTTCTGCCT CCCCATATGC CTCGGACACC ACGCCCTGCT GCTTTGCCTA TATCTCCCGC 
CCGCTGCCCC GCACCCACGT CCAGGAGTAT TTCTACACCA GCAGCAAGTG CTCCATGGCA 
GCAGTTGTCT TTATCACCAG GAAGAAGCGC CAGGTGTGCG CCAACCCAGA GAAGAAGTGG 
GTGCGAGAGT ACATCAACGC TTTGGAGTTG AGCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Live and inactivated Salmonella enterica serovar Typhimurium stimulate similar but distinct transcriptome profiles in bovine macrophages and dendritic cells.
Veterinary research4746(2016 Mar)
Jensen K,Gallagher IJ,Kaliszewska A,Zhang C,Abejide O,Gallagher MP,Werling D,Glass EJ

The chemokine CCL5 induces selective migration of bovine classical monocytes and drives their differentiation into LPS-hyporesponsive macrophages in vitro.
Developmental and comparative immunology47(2)169-77(2014 Dec)
Hussen J,Frank C,D?vel A,Koy M,Schuberth HJ

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Decreasing sensitivity to RANTES (regulated on activation, normally T cell-expressed and -secreted) neutralization of CC chemokine receptor 5-using, non-syncytium-inducing virus variants in the course of human immunodeficiency virus type 1 infection.
The Journal of infectious diseases188(6)864-72(2003 Sep)
Koning FA,Kwa D,Boeser-Nunnink B,Dekker J,Vingerhoed J,Hiemstra H,Schuitemaker H

Cloning of bovine RANTES mRNA and its expression and regulation in ovaries in the periovulatory period.
FEBS letters463(1-2)160-4(1999 Dec)
Aust G,Brylla E,Lehmann I,Kiessling S,Spanel-Borowski K

- Most Popular Services
  - 人工遺伝子合成& DNA合成-納期保証
- Services & Products

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

CCL5 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Most Popular Services

Services & Products

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報