ITPR1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	ITPR1
Entrez Gene ID	317697
Full Name	inositol 1,4,5-trisphosphate receptor type 1
General protein information	Preferred Names inositol 1,4,5-trisphosphate receptor type 1 Names inositol 1,4,5-trisphosphate receptor type 1 IP3 receptor IP3R 1 inositol 1,4,5-triphosphate receptor, type 1 insP3R1 type 1 InsP3 receptor type 1 inositol 1,4,5-trisphosphate receptor
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_174841.2	NP_777266.1	inositol 1,4,5-trisphosphate receptor type 1

Pathways from BioSystems

Homologies

Anopheles gambiae (African malaria mosquito)	AgaP_AGAP006475	XP_557157.3
	ITPR1	XP_002802774.1
Bos taurus (cattle)	ITPR1	NP_777266.1
Homo sapiens (human)	ITPR1	NP_001161744.1
Mus musculus (house mouse)	Itpr1	NP_034715.3
Gallus gallus (chicken)	ITPR1	NP_001167530.1
Rattus norvegicus (Norway rat)	Itpr1	NP_001007236.2
Caenorhabditis elegans (roundworm)	itr-1	NP_001023172.1
Pan troglodytes (chimpanzee)	ITPR1	XP_003309639.2
Canis lupus familiaris (dog)	ITPR1	XP_003639763.1
Danio rerio (zebrafish)	itpr1	XP_001921194.3
Drosophila melanogaster (fruit fly)	Itp-r83A	NP_730941.1
Xenopus tropicalis (tropical clawed frog)	itpr1	XP_002938363.2

Gene Ontology
Bibliography

Related articles in PubMed

STIM1 positively regulates the Ca2+ release activity of the inositol 1,4,5-trisphosphate receptor in bovine aortic endothelial cells.
B?liveau ?, Lessard V, Guillemette G
PloS one9(12)e114718(2014)

Global dynamic conformational changes in the suppressor domain of IP3 receptor by stepwise binding of the two lobes of calmodulin.
Kang S, Kwon H, Wen H, Song Y, Frueh D, Ahn HC, Yoo SH, Wagner G, Park S
FASEB journal : official publication of the Federation of American Societies for Experimental Biology25(3)840-50(2011 Mar)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Effects of redox potential and Ca2+ on the inositol 1,4,5-trisphosphate receptor L3-1 loop region: implications for receptor regulation.
Kang S, Kang J, Kwon H, Frueh D, Yoo SH, Wagner G, Park S
The Journal of biological chemistry283(37)25567-75(2008 Sep)

A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel.
Thrower EC, Choe CU, So SH, Jeon SH, Ehrlich BE, Yoo SH
The Journal of biological chemistry278(50)49699-706(2003 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

STIM1 and STIM2 are expressed in bovine aortic endothelial cells and they both interact with IP3R-1.
Title: STIM1 positively regulates the Ca2+ release activity of the inositol 1,4,5-trisphosphate receptor in bovine aortic endothelial cells.

we propose a model in which the partial unfolding of the suppressor domain by apo-CaM and the stepwise binding of the N lobe of CaM to the suppressor domain are important elements of calcium/CaM inhibition of IP(3)R
Title: Global dynamic conformational changes in the suppressor domain of IP3 receptor by stepwise binding of the two lobes of calmodulin.

the redox potential and Ca(2+) can regulate IP(3)R through totally different mechanisms: Ca(2+) by the indirect effect and the redox potential by direct action causing conformational changes
Title: Effects of redox potential and Ca2+ on the inositol 1,4,5-trisphosphate receptor L3-1 loop region: implications for receptor regulation.

the InsP3R/Ca2+ channel is regulated by chromogranin B
Title: A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel.

structural mapping of the amino acid sequences to several functional domains is deduced within the structure of the InsP3R1 tetramer
Title: Structure of the type 1 inositol 1,4,5-trisphosphate receptor revealed by electron cryomicroscopy.

The following ITPR1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the ITPR1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa42336	NM_174841.2 Latest version!	Bos taurus inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	Quote Price

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Next-day Shipping ORF Clones ( in default vector with tag)
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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

ITPR1 ( NM_174841.2 ) cDNA ORF clone, Bos taurus(cattle) -> NP_777266.1 Bos taurus inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), mRNA.

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CloneID	OBa42336
Clone ID Related Accession (Same CDS sequence)	NM_174841.2
Accession Version	NM_174841.2 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 8130bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-26
Organism	Bos taurus(cattle)
Product	inositol 1,4,5-trisphosphate receptor type 1
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AF157625.1. On or before Mar 29, 2005 this sequence version replaced XM_610543.1, NM_174841.1. ##Evidence-Data-START## Transcript exon combination :: AF157625.1 [ECO:0000332] ##Evidence-Data-END##

ATGTCTGACA AGATGTCTAG TTTCCTACAC ATCGGAGACA TTTGTTCTCT GTACGCCGAA 
GGATCGACAA ATGGATTTAT TAGCACCTTG GGCCTGGTTG ATGACCGTTG TGTTGTGCAG 
CCAGAAACCG GGGACCTTAA CAATCCACCC AAGAAATTCA GAGATTGCCT CTTTAAACTA 
TGTCCCATGA ATCGCTACTC TGCCCAGAAG CAGTTCTGGA AAGCTGCTAA GCCAGGAGCC 
AACAGCACGA CAGACGCAGT GCTGCTCAAC AAATTGCACC ATGCTGCAGA CTTGGAAAAG 
AAGCAGAATG AGACTGAAAA CAGGAAGTTG CTGGGTACCG TGATCCAGTA TGGCAACGTG 
ATCCAGCTAC TGCATCTGAA AAGTAATAAA TACCTAACTG TGAATAAGAG GCTTCCGGCT 
CTGCTGGAGA AGAATGCCAT GAGAGTGACA TTGGATGAGG CCGGAAACGA AGGGTCCTGG 
TTTTACATTC AGCCATTCTA CAAGCTGCGA TCCATCGGAG ACAGTGTGGT CATAGGTGAC 
AAGGTTGTTC TGAACCCCGT GAATGCCGGC CAGCCCTTAC ATGCCAGCAG CCATCAGCTG 
GTGGATAACC CAGGCTGCAA CGAGGTCAAT TCCGTCAACT GCAATACAAG CTGGAAAATA 
GTCCTTTTCA TGAAATGGAG TGACAACAAA GATGACATAT TAAAGGGGGG TGACGTGGTG 
AGGCTGTTCC ATGCCGAGCA GGAGAAGTTT CTCACCTGTG ACGAGCACAG GAAGAAGCAG 
CACGTCTTTC TGAGAACCAC CGGCCGGCAG TCTGCCACGT CCGCCACCAG CTCAAAAGCC 
CTGTGGGAGG TGGAGGTGGT CCAACATGAC CCATGTCGGG GAGGAGCAGG GTACTGGAAC 
AGCCTCTTCC GTTTCAAGCA TCTTGCTACC GGGCATTACT TAGCAGCAGA GGTAGACCCT 
GACTTTGAGG AAGAATGCCT GGAGTTTCAG CCCTCAGTGG ACCCTGATCA GGATGCCTCC 
CGAAGCAGGT TGCGAAATGC CCAAGAGAAG ATGGTGTACT CCCTGGTCTC TGTGCCCGAG 
GGCAATGACA TCTCCTCCAT TTTTGAGCTG GACCCCACGA CGCTCCGTGG AGGCGACAGC 
CTCGTCCCGA GAAACTCCTA TGTCCGGCTC CGACACCTGT GTACAAATAC CTGGGTTCAC 
AGCACAAACA TCCCCATTGA CAAGGAAGAA GAAAAACCCG TGATGCTGAA AATTGGCACT 
TCTCCCGTGA AGGAGGACAA GGAAGCCTTT GCCATAGTGC CAGTCTCTCC TGCTGAGGTT 
CGGGATCTGG ACTTTGCCAA TGACGCCAGC AAGGTGCTGG GCTCCATAGC GGGCAAGTTG 
GAGAAGGGCA CCATCACCCA GAATGAAAGA AGATCTGTAA CCAAGCTGCT GGAAGACTTG 
GTTTACTTTG TCACTGGCGG AACCAATTCT GGTCAAGATG TTCTTGAAGT GGTCTTCTCC 
AAGCCCAACA GAGAGCGTCA GAAGCTCATG AGAGAACAGA ATATTCTCAA GCAGATCTTC 
AAGCTATTAC AGGCCCCATT CACAGACTGT GGTGACGGCC CAATGCTGCG TCTGGAGGAG 
CTGGGAGACC AGCGGCACGC ACCCTTCCGA CACATCTGCC GCCTTTGCTA CCGGGTCCTG 
AGACATTCCC AGCAGGACTA CAGGAAGAAC CAGGAGTACA TAGCCAAGCA GTTCGGCTTC 
ATGCAGAAGC AGATTGGCTA TGACGTGCTG GCCGAAGACA CTATCACCGC CCTTCTGCAC 
AATAATCGCA AACTCCTGGA AAAACACATC ACCGCGGCAG AGATTGACAC CTTCGTCAGC 
CTGGTGCGGA AGAACAGGGA GCCCAGATTC TTAGATTACC TCTCTGACCT CTGCGTGTCC 
ATGAACAAAT CCATTCCGGT GACTCAGGAA CTGATATGTA AAGCCGTGCT GAATCCAACC 
AATGCCGACA TCCTCATTGA GACCAAGTTG GTGCTCTCCC GTTTTGAATT TGAAGGCGTT 
TCTACCGGAG AGAACGCTCT GGAGGCAGGC GAGGATGAGG AAGAAGTATG GGTCTTCTGG 
AGGGACAGCA ACAAGGAGGT TCGCAGTAAG AGTGTCCGGG AGCTGGCGCA GGATGCCAAG 
GAGGGCCAGA AGGAAGACCG CGACGTCCTT GGCTACTACA GGTACCAGCT GAACCTCTTT 
GCGAGGATGT GCCTGGACCG CCAGTACCTT GCCATCAACG AGATCTCGGG CCAACTGGAC 
GTGGATCTCA TTCTCCGCTG CATGTCCGAC GAGAACCTGC CCTCCGACCT GCGGGCATCC 
TTCTGCCGTC TCATGCTCCA CATGCACGTG GACCGAGACC CCCAGGAGCA GGTCACCCCC 
GTGAAATACG CCCGCCTCTG GTCTGAGATC CCCTCCGAAA TCGCCATTGA TGACTACGAT 
AGTAGTGGAA CCTCCAAAGA TGAAATTAAG GAGAGGTTCG CTCAGACCAT GGAATTTGTG 
GAGGAATATT TAAGAGATGT GGTGTGTCAG AGGTTCCCTT TCTCTGATAA GGAGAAAAAT 
AAGCTTACAT TTGAGGTTGT CAACCTAGCT AGGAATCTCA TCTACTTTGG TTTCTACAAC 
TTTTCCGACC TTCTCCGATT AACCAAAATC CTCCTGGCCA TATTGGACTG TGTGCACGTG 
ACCACAATCT TCCCCATCAG CAAGATGGCG AAGGGAGAGG AGAATAAAGG CAGTAACGTG 
ATGCGGTCCA TCCATGGGGT CGGAGAGCTG ATGACCCAGG TGGTGCTCCG GGGAGGAGGC 
TTCCTGCCCA TGACACCCAC GGCCACCGCC CCTGAGGGCA ACGTGAAGCA GGCCGAGCCG 
GAGAAGGAGG ACATCATGGT GATGGACACC AAGCTGAAGA TCATTGAAAT ACTCCAGTTT 
ATTTTGAATG TGAGGTTGGA TTATAGGATC TCCTGCCTCC TGTGTATATT TAAGCGGGAG 
TTTGATGAAA GCAATTCCCA GACTTCAGAA ACATCCTCCG GAAACAGCAG CCAAGAAGGA 
CCAAGTAATG TGCCAGGTGC TCTTGACTTT GAACACATTG AAGAACAAGC TGAGGGCATC 
TTCGGAGGAA GTGAGGAGAC CACCCCGCTG GACCTGGATG ACCACGGCGG CAGAACTTTC 
CTCCGAGTCC TGCTCCACTT GACGATGCAC GACTACCCAC CCCTGGTGTC GGGGGCCCTG 
CAGCTCCTCT TTCGGCACTT CAGTCAGAGA CAGGAGGTCC TCCAGGCCTT CAAACAGGTT 
CAGCTGCTCG TTACCAGCCA AGATGTCGAT AACTACAAGC AGATAAAACA AGACCTGGAC 
CAGCTGAGAT CCATCGTGGA GAAGTCAGAG CTCTGGGTGT ACAAAGGGCA GGGCCCCGAC 
GAGGCCATGG ACGGCGCATC TGGAGAAAAC GAGCATAAGA AGACAGAGGA GGGGAATAAC 
AAGTCACAGC AGCATGAGAG CACCAGCAGC TACAACTACA GGGTGGTCAA AGAGATTTTG 
ATCCGACTCA GCAAACTCTG TGTTCAAGAG AGCGCATCCG TGCGGAAGAG CAGGAAGCAG 
CAACAGCGCT TGCTCCGGAA CATGGGCGCC CACGCCGTGG TGCTGGAGCT GCTGCAGATC 
CCCTACGAGA AGGCTGAAGA CACCATGATG CAGGAGATAA TGAGGCTGGC TCATGAGTTT 
CTTCAGAATT TCTGCGCCGG CAACCACCCT AATCAGGCTC TGCTCCACAA ACATATTAAC 
CTGTTTCTAA ACCCAGGGAT CCTGGAAGCC GTCACGATGC AGCACATCTT CATGAACAAC 
TTCCAACTGT GCAGCGAGAT CAACGAGCGG GTCGTCCAGC ACTTTGTTCA CTGCATCGAG 
ACTCACGGTC GAAATGTCCA GTACATCAAG TTCCTGCAGA CGATTGTCAA GGCTGAAGGG 
AAATTCATCA AGAAGTGCCA AGACATGGTC ATGGCCGAGC TGGTTAATTC AGGAGAGGAT 
GTCCTCGTGT TCTACAACGA CAGAGCCTCT TTCCAGACCC TGATTCAGAT GATGAGGTCC 
GAGCGGGACC GGATGGACGA GAACAGCCCC CTCATGTACC ACATCCATCT GGTGGAGCTC 
TTGGCCGTGT GCACAGAGGG CAAGAACGTC TACACGGAGA TCAAATGCAA CTCCCTGCTC 
CCACTGGATG ACATTGTCCG CGTGGTGACC CACGAGGACT GCATCCCCGA GGTTAAAATT 
GCCTACATTA ACTTCCTGAA TCACTGCTAT GTGGACCCGG AAGTGGAAAT GAAGGAGATT 
TATACCAGCA ATCACATGTG GAAATTGTTT GAGAATTTCC TCGTCGACAT CTGCAGGGCC 
TGTAACAACA CGAGCGACAG GAAACACGCA GACTCGATTC TGGAGAAGTA CGTCACCGAA 
ATCGTCATGA GCATCGTCAC CACGTTCTTC AGTTCTCCCT TCTCAGACCA GAGTACAACT 
CTGCAGACTC GCCAGCCCGT CTTTGTGCAG CTTCTGCAAG GTGTGTTCCG GGTTTACCAC 
TGCAACTGGC TCATGCCAAG CCAGAAGGCC TCGGTGGAGA GCTGCATCCG GGTGCTCTCT 
GATGTAGCCA AGAGCCGGGC CATTGCCATT CCCGTGGACT TGGACAGTCA GGTCAACAAC 
CTCTTCCTCA AGTCCCACAA CCTCGTGCAG AAAACCGCCA TGAACTGGCG GCTGACGGCC 
CGCAATGCTG CCCGCAGAGA TTCTGTCCTG CCCGTTTCCA GGGACTACCG GAACATCATC 
GAGAGACTGC AGGACATTGT CTCGGCCCTG GAGGACCGTC TCCGGCCCCT GGTGCAGGCC 
GAGTTATCTG TGCTGGTGGA TGTCCTCCAC CGGCCCGAGC TGCTCTTCCC GGAGAACACG 
GACGCCAGGA GGAAGTGTGA AAGCGGGGGC TTCATCTGCA AGTTAATCAA ACACACTAAA 
CAGCTGCTGG AGGAGAATGA GGAGAAACTC TGCATCAAGG TCCTTCAGAC CCTCAGAGAA 
ATGATGACCA AAGACAGAGG CTATGGAGAA AAGGGTGAGG CCCTCAGGCA GATTTTGGTC 
AACCGTTACT ATGGAAACAT CAGACCTTCG GGAAGAAGAG AGAGCCTCAC GAGCTTTGGC 
AATGGCCCGC TGTCGCCAGG AGGACCCAGC AAGCCTGGGG GAGGAGGGGG AGGTTCCGGA 
TCCAGCCCCA TGAGCAGGGG TGAAATGAGC CTGGCCGAGG TTCAGTGCCA CCTTGACAAG 
GAGGGGGCCT CCAACCTGGT TATCGACCTC ATCATGAACG CATCCAGTGA CCGAGTGTTC 
CATGAAAGCA TTCTTCTAGC CATCGCCCTG CTGGAAGGAG GCAACACCAC CATACAGCAC 
TCCTTTTTCT GCCGGTTGAC AGAAGACAAG AAGTCAGAGA AATTCTTCAA GGTTTTCTAT 
GACCGAATGA AGGTGGCCCA GCAGGAAATC AAGGCAACAG TGACCGTGAA CACCAGTGAC 
TTGGGAAATA AAAAGAAAGA TGACGAGGTG GACAGGGATG CCCCGTCACG GAAAAAAGCC 
AAAGAGCCTG CGACGCAGAT TACGGAAGAG GTGCGGGATC AGCTCTTGGA GGCCTCTGCT 
GCCACCCGCA AAGCCTTCAC CACCTTCAGA AGGGAAGCTG ACCCCGACGA CCACTACCAG 
TCCGGGGAGG GCGCCCAGGC CGCGGCGGAC AAGAGCAAGG ACGACCTGGA GATGAGCGCG 
GTCATCACCA TCATGCAGCC CATCCTCCGC TTCCTGCAGC TGCTGTGCGA AAACCACAAC 
CGGGACCTCC AGAACTTCCT CCGTTGCCAA AACAACAAGA CCAACTACAA TTTGGTGTGC 
GAGACACTGC AGTTTCTGGA CTGTATTTGT GGAAGCACCA CCGGGGGTCT TGGTCTTCTG 
GGACTCTATA TCAACGAAAA GAACGTGGCC CTCATCAACC AAACCCTGGA AAGTTTGACT 
GAATACTGTC AAGGACCTTG CCATGAGAAT CAGAACTGCA TAGCCACCCA TGAATCCAAT 
GGCATTGACA TCATCACAGC CCTGATCCTC AATGACATCA ACCCTCTGGG AAAGAAAAGG 
ATGGACCTTG TGTTAGAACT GAAGAACAAT GCGTCCAAGT TGCTCCTGGC CATCATGGAG 
AGCAGGCATG ACAGTGAGAA TGCTGAGCGG ATCCTCTATA ACATGAGGCC CAAGGAACTG 
GTGGAAGTGA TCAAGAAAGC CTACATGCAA GGTGAAGTGG AGTTCGAGGA TGGTGAGAAT 
GGTGAGGACG GAGCTGCCTC CCCCAGAAAC GTGGGACACA ACATCTACAT CCTAGCTCAT 
CAGTTGGCTC GACATAACAA AGAACTTCAA ACCATGCTGA AACCCGGCGG GCAAGTGGAT 
GGAGACGAAA CTCTGGATTT TTATGCCCAG CCCACCGGCC CAAATGAGAT TGTCAGGTTA 
GACCGAACCA TGGAGCAGAT TGTCTTCCCC GTGCCCAGTA TATGTGAATT CCTAACCAAA 
GAGTCAAAAC TACGGATATA CTACACCACA GAGAGGGACG AGCAGGGCAG CAAGATCAAC 
GACTTCTTCC TGCGGTCCGA GGACCTCTTC AATGAGATGA ATTGGCAGAA GAAGCTCAGA 
GCCCAGCCCG TCCTGTACTG GTGCGCCCGC AACATGTCTT TCTGGAGTAG CATTTCATTC 
AACCTGGCCG TCCTGATGAA CCTGCTTGTG GCGTTTTTCT ACCCTTTTAA AGGAGTCCGA 
GGAGGGACCC TGGAACCGCA CTGGTCGGGA CTGCTGTGGA CGGCCATGCT CATCTCTCTG 
GCCATCGTCA TCGCCCTCCC CAAGCCCCAT GGCATCCGGG CCTTAATCGC TTCCACGATT 
CTCCGGTTGA TATTTTCCGT CGGGCTACAA CCCACGCTGT TTCTTTTGGG AGCTTTCAAC 
GTCTGCAATA AAATCATTTT TCTGATGAGC TTTGTGGGCA ACTGTGGGAC ATTCACCAGA 
GGCTACCGGG CCATGGTTCT GGATGTTGAG TTCCTTTATC ACCTGCTANA CCTGCTGATC 
TGCGCCATGG GGCTCTTCGT CCATGAGTTC TTCTACAGTT TGCTGCTTTT TGATTTAGTG 
TACAGAGAAG AGACTCTGCT CAATGTCATT AAAAGCGTCA CTCGCAACGG CCGGTCCATC 
ATCTTGATGG CGGTTCTGGC TTTGATCCTG GTTTACCTGT TCTCCATAGT GGGCTACCTT 
TTCTTCAAAG ATGACTTCAT CTTGGAAGTA GATAGGCTGC CCAATGAAAC CTCTCTTCCA 
GAAGCCAGCG AGAGTTTGGC AAGTGAGTTC CTGTACTCTG ACGTGTGTAG GGTGGAGACT 
GGGGAGAACT GCTCCTCTCC GGCACCCAAA GAAGAGCTGG TCCCTGCAGA AGAGACAGAG 
CAAGATAAAG AGCACACGTG CGAGACGCTG CTGATGTGCA TCGTCACGGT GCTGAGTCAC 
GGGCTGCGGA GCGGGGGCGG AGTGGGCGAT GTGCTCAGGA AGCCATCCAA AGAGGAGCCC 
CTCTTTGCTG CTCGAGTGAT CTATGACCTC TTGTTCTTCT TCATGGTCAT CATCATTGTC 
CTTAATCTGA TTTTTGGGGT CATCATTGAC ACCTTTGCCG ACCTGAGGAG TGAAAAACAG 
AAAAAAGAGG AGATATTAAA GACCACGTGC TTTATCTGCG GGTTGGAAAG AGACAAGTTT 
GACAACAAGA CCGTCACATT TGAAGAGCAC ATCAAGGAAG AACACAACAT GTGGCATTAC 
CTGTGCTTCA TCGTCCTGGT GAAAGTGAAG GACTCCACGG AGTACACAGG GCCCGAAAGT 
TACGTGGCAG AGATGATCAA GGAAAGAAAC CTAGACTGGT TCCCGAGGAT GAGAGCCATG 
TCCCTGGTCA GCAGCGATTC AGAAGGAGAG CAGAATGAGC TGAGGAACCT GCAGGAGAAG 
CTGGAGTCCA CCATGAAGCT TGTCACCAAC CTCTCTGGAC TGCTGTCAGA ATTAAAGGAT 
CAGATGACAG ATCAAAGGAA GCAGAAACAA AGAATGGGTC TTCTAGGACA TCCTCCTCAC 
ATCAATGTCA ACCCACAGCA ACCAGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777266.1
CDS	231..8360
Translation	MSDKMSSFLHIGDICSLYAEGSTNGFISTLGLVDDRCVVQPETGDLNNPPKKFRDCLFKLCPMNRYSAQKQFWKAAKPGANSTTDAVLLNKLHHAADLEKKQNETENRKLLGTVIQYGNVIQLLHLKSNKYLTVNKRLPALLEKNAMRVTLDEAGNEGSWFYIQPFYKLRSIGDSVVIGDKVVLNPVNAGQPLHASSHQLVDNPGCNEVNSVNCNTSWKIVLFMKWSDNKDDILKGGDVVRLFHAEQEKFLTCDEHRKKQHVFLRTTGRQSATSATSSKALWEVEVVQHDPCRGGAGYWNSLFRFKHLATGHYLAAEVDPDFEEECLEFQPSVDPDQDASRSRLRNAQEKMVYSLVSVPEGNDISSIFELDPTTLRGGDSLVPRNSYVRLRHLCTNTWVHSTNIPIDKEEEKPVMLKIGTSPVKEDKEAFAIVPVSPAEVRDLDFANDASKVLGSIAGKLEKGTITQNERRSVTKLLEDLVYFVTGGTNSGQDVLEVVFSKPNRERQKLMREQNILKQIFKLLQAPFTDCGDGPMLRLEELGDQRHAPFRHICRLCYRVLRHSQQDYRKNQEYIAKQFGFMQKQIGYDVLAEDTITALLHNNRKLLEKHITAAEIDTFVSLVRKNREPRFLDYLSDLCVSMNKSIPVTQELICKAVLNPTNADILIETKLVLSRFEFEGVSTGENALEAGEDEEEVWVFWRDSNKEVRSKSVRELAQDAKEGQKEDRDVLGYYRYQLNLFARMCLDRQYLAINEISGQLDVDLILRCMSDENLPSDLRASFCRLMLHMHVDRDPQEQVTPVKYARLWSEIPSEIAIDDYDSSGTSKDEIKERFAQTMEFVEEYLRDVVCQRFPFSDKEKNKLTFEVVNLARNLIYFGFYNFSDLLRLTKILLAILDCVHVTTIFPISKMAKGEENKGSNVMRSIHGVGELMTQVVLRGGGFLPMTPTATAPEGNVKQAEPEKEDIMVMDTKLKIIEILQFILNVRLDYRISCLLCIFKREFDESNSQTSETSSGNSSQEGPSNVPGALDFEHIEEQAEGIFGGSEETTPLDLDDHGGRTFLRVLLHLTMHDYPPLVSGALQLLFRHFSQRQEVLQAFKQVQLLVTSQDVDNYKQIKQDLDQLRSIVEKSELWVYKGQGPDEAMDGASGENEHKKTEEGNNKSQQHESTSSYNYRVVKEILIRLSKLCVQESASVRKSRKQQQRLLRNMGAHAVVLELLQIPYEKAEDTMMQEIMRLAHEFLQNFCAGNHPNQALLHKHINLFLNPGILEAVTMQHIFMNNFQLCSEINERVVQHFVHCIETHGRNVQYIKFLQTIVKAEGKFIKKCQDMVMAELVNSGEDVLVFYNDRASFQTLIQMMRSERDRMDENSPLMYHIHLVELLAVCTEGKNVYTEIKCNSLLPLDDIVRVVTHEDCIPEVKIAYINFLNHCYVDPEVEMKEIYTSNHMWKLFENFLVDICRACNNTSDRKHADSILEKYVTEIVMSIVTTFFSSPFSDQSTTLQTRQPVFVQLLQGVFRVYHCNWLMPSQKASVESCIRVLSDVAKSRAIAIPVDLDSQVNNLFLKSHNLVQKTAMNWRLTARNAARRDSVLPVSRDYRNIIERLQDIVSALEDRLRPLVQAELSVLVDVLHRPELLFPENTDARRKCESGGFICKLIKHTKQLLEENEEKLCIKVLQTLREMMTKDRGYGEKGEALRQILVNRYYGNIRPSGRRESLTSFGNGPLSPGGPSKPGGGGGGSGSSPMSRGEMSLAEVQCHLDKEGASNLVIDLIMNASSDRVFHESILLAIALLEGGNTTIQHSFFCRLTEDKKSEKFFKVFYDRMKVAQQEIKATVTVNTSDLGNKKKDDEVDRDAPSRKKAKEPATQITEEVRDQLLEASAATRKAFTTFRREADPDDHYQSGEGAQAAADKSKDDLEMSAVITIMQPILRFLQLLCENHNRDLQNFLRCQNNKTNYNLVCETLQFLDCICGSTTGGLGLLGLYINEKNVALINQTLESLTEYCQGPCHENQNCIATHESNGIDIITALILNDINPLGKKRMDLVLELKNNASKLLLAIMESRHDSENAERILYNMRPKELVEVIKKAYMQGEVEFEDGENGEDGAASPRNVGHNIYILAHQLARHNKELQTMLKPGGQVDGDETLDFYAQPTGPNEIVRLDRTMEQIVFPVPSICEFLTKESKLRIYYTTERDEQGSKINDFFLRSEDLFNEMNWQKKLRAQPVLYWCARNMSFWSSISFNLAVLMNLLVAFFYPFKGVRGGTLEPHWSGLLWTAMLISLAIVIALPKPHGIRALIASTILRLIFSVGLQPTLFLLGAFNVCNKIIFLMSFVGNCGTFTRGYRAMVLDVEFLYHLLnullLLICAMGLFVHEFFYSLLLFDLVYREETLLNVIKSVTRNGRSIILMAVLALILVYLFSIVGYLFFKDDFILEVDRLPNETSLPEASESLASEFLYSDVCRVETGENCSSPAPKEELVPAEETEQDKEHTCETLLMCIVTVLSHGLRSGGGVGDVLRKPSKEEPLFAARVIYDLLFFFMVIIIVLNLIFGVIIDTFADLRSEKQKKEEILKTTCFICGLERDKFDNKTVTFEEHIKEEHNMWHYLCFIVLVKVKDSTEYTGPESYVAEMIKERNLDWFPRMRAMSLVSSDSEGEQNELRNLQEKLESTMKLVTNLSGLLSELKDQMTDQRKQKQRMGLLGHPPHINVNPQQPA

Target ORF information:

RefSeq Version	NM_174841.2
Organism	Bos taurus(cattle)
Definition	Bos taurus inositol 1,4,5-trisphosphate receptor type 1 (ITPR1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174841.2

ORF Insert Sequence:

ATGTCTGACA AGATGTCTAG TTTCCTACAC ATCGGAGACA TTTGTTCTCT GTACGCCGAA 
GGATCGACAA ATGGATTTAT TAGCACCTTG GGCCTGGTTG ATGACCGTTG TGTTGTGCAG 
CCAGAAACCG GGGACCTTAA CAATCCACCC AAGAAATTCA GAGATTGCCT CTTTAAACTA 
TGTCCCATGA ATCGCTACTC TGCCCAGAAG CAGTTCTGGA AAGCTGCTAA GCCAGGAGCC 
AACAGCACGA CAGACGCAGT GCTGCTCAAC AAATTGCACC ATGCTGCAGA CTTGGAAAAG 
AAGCAGAATG AGACTGAAAA CAGGAAGTTG CTGGGTACCG TGATCCAGTA TGGCAACGTG 
ATCCAGCTAC TGCATCTGAA AAGTAATAAA TACCTAACTG TGAATAAGAG GCTTCCGGCT 
CTGCTGGAGA AGAATGCCAT GAGAGTGACA TTGGATGAGG CCGGAAACGA AGGGTCCTGG 
TTTTACATTC AGCCATTCTA CAAGCTGCGA TCCATCGGAG ACAGTGTGGT CATAGGTGAC 
AAGGTTGTTC TGAACCCCGT GAATGCCGGC CAGCCCTTAC ATGCCAGCAG CCATCAGCTG 
GTGGATAACC CAGGCTGCAA CGAGGTCAAT TCCGTCAACT GCAATACAAG CTGGAAAATA 
GTCCTTTTCA TGAAATGGAG TGACAACAAA GATGACATAT TAAAGGGGGG TGACGTGGTG 
AGGCTGTTCC ATGCCGAGCA GGAGAAGTTT CTCACCTGTG ACGAGCACAG GAAGAAGCAG 
CACGTCTTTC TGAGAACCAC CGGCCGGCAG TCTGCCACGT CCGCCACCAG CTCAAAAGCC 
CTGTGGGAGG TGGAGGTGGT CCAACATGAC CCATGTCGGG GAGGAGCAGG GTACTGGAAC 
AGCCTCTTCC GTTTCAAGCA TCTTGCTACC GGGCATTACT TAGCAGCAGA GGTAGACCCT 
GACTTTGAGG AAGAATGCCT GGAGTTTCAG CCCTCAGTGG ACCCTGATCA GGATGCCTCC 
CGAAGCAGGT TGCGAAATGC CCAAGAGAAG ATGGTGTACT CCCTGGTCTC TGTGCCCGAG 
GGCAATGACA TCTCCTCCAT TTTTGAGCTG GACCCCACGA CGCTCCGTGG AGGCGACAGC 
CTCGTCCCGA GAAACTCCTA TGTCCGGCTC CGACACCTGT GTACAAATAC CTGGGTTCAC 
AGCACAAACA TCCCCATTGA CAAGGAAGAA GAAAAACCCG TGATGCTGAA AATTGGCACT 
TCTCCCGTGA AGGAGGACAA GGAAGCCTTT GCCATAGTGC CAGTCTCTCC TGCTGAGGTT 
CGGGATCTGG ACTTTGCCAA TGACGCCAGC AAGGTGCTGG GCTCCATAGC GGGCAAGTTG 
GAGAAGGGCA CCATCACCCA GAATGAAAGA AGATCTGTAA CCAAGCTGCT GGAAGACTTG 
GTTTACTTTG TCACTGGCGG AACCAATTCT GGTCAAGATG TTCTTGAAGT GGTCTTCTCC 
AAGCCCAACA GAGAGCGTCA GAAGCTCATG AGAGAACAGA ATATTCTCAA GCAGATCTTC 
AAGCTATTAC AGGCCCCATT CACAGACTGT GGTGACGGCC CAATGCTGCG TCTGGAGGAG 
CTGGGAGACC AGCGGCACGC ACCCTTCCGA CACATCTGCC GCCTTTGCTA CCGGGTCCTG 
AGACATTCCC AGCAGGACTA CAGGAAGAAC CAGGAGTACA TAGCCAAGCA GTTCGGCTTC 
ATGCAGAAGC AGATTGGCTA TGACGTGCTG GCCGAAGACA CTATCACCGC CCTTCTGCAC 
AATAATCGCA AACTCCTGGA AAAACACATC ACCGCGGCAG AGATTGACAC CTTCGTCAGC 
CTGGTGCGGA AGAACAGGGA GCCCAGATTC TTAGATTACC TCTCTGACCT CTGCGTGTCC 
ATGAACAAAT CCATTCCGGT GACTCAGGAA CTGATATGTA AAGCCGTGCT GAATCCAACC 
AATGCCGACA TCCTCATTGA GACCAAGTTG GTGCTCTCCC GTTTTGAATT TGAAGGCGTT 
TCTACCGGAG AGAACGCTCT GGAGGCAGGC GAGGATGAGG AAGAAGTATG GGTCTTCTGG 
AGGGACAGCA ACAAGGAGGT TCGCAGTAAG AGTGTCCGGG AGCTGGCGCA GGATGCCAAG 
GAGGGCCAGA AGGAAGACCG CGACGTCCTT GGCTACTACA GGTACCAGCT GAACCTCTTT 
GCGAGGATGT GCCTGGACCG CCAGTACCTT GCCATCAACG AGATCTCGGG CCAACTGGAC 
GTGGATCTCA TTCTCCGCTG CATGTCCGAC GAGAACCTGC CCTCCGACCT GCGGGCATCC 
TTCTGCCGTC TCATGCTCCA CATGCACGTG GACCGAGACC CCCAGGAGCA GGTCACCCCC 
GTGAAATACG CCCGCCTCTG GTCTGAGATC CCCTCCGAAA TCGCCATTGA TGACTACGAT 
AGTAGTGGAA CCTCCAAAGA TGAAATTAAG GAGAGGTTCG CTCAGACCAT GGAATTTGTG 
GAGGAATATT TAAGAGATGT GGTGTGTCAG AGGTTCCCTT TCTCTGATAA GGAGAAAAAT 
AAGCTTACAT TTGAGGTTGT CAACCTAGCT AGGAATCTCA TCTACTTTGG TTTCTACAAC 
TTTTCCGACC TTCTCCGATT AACCAAAATC CTCCTGGCCA TATTGGACTG TGTGCACGTG 
ACCACAATCT TCCCCATCAG CAAGATGGCG AAGGGAGAGG AGAATAAAGG CAGTAACGTG 
ATGCGGTCCA TCCATGGGGT CGGAGAGCTG ATGACCCAGG TGGTGCTCCG GGGAGGAGGC 
TTCCTGCCCA TGACACCCAC GGCCACCGCC CCTGAGGGCA ACGTGAAGCA GGCCGAGCCG 
GAGAAGGAGG ACATCATGGT GATGGACACC AAGCTGAAGA TCATTGAAAT ACTCCAGTTT 
ATTTTGAATG TGAGGTTGGA TTATAGGATC TCCTGCCTCC TGTGTATATT TAAGCGGGAG 
TTTGATGAAA GCAATTCCCA GACTTCAGAA ACATCCTCCG GAAACAGCAG CCAAGAAGGA 
CCAAGTAATG TGCCAGGTGC TCTTGACTTT GAACACATTG AAGAACAAGC TGAGGGCATC 
TTCGGAGGAA GTGAGGAGAC CACCCCGCTG GACCTGGATG ACCACGGCGG CAGAACTTTC 
CTCCGAGTCC TGCTCCACTT GACGATGCAC GACTACCCAC CCCTGGTGTC GGGGGCCCTG 
CAGCTCCTCT TTCGGCACTT CAGTCAGAGA CAGGAGGTCC TCCAGGCCTT CAAACAGGTT 
CAGCTGCTCG TTACCAGCCA AGATGTCGAT AACTACAAGC AGATAAAACA AGACCTGGAC 
CAGCTGAGAT CCATCGTGGA GAAGTCAGAG CTCTGGGTGT ACAAAGGGCA GGGCCCCGAC 
GAGGCCATGG ACGGCGCATC TGGAGAAAAC GAGCATAAGA AGACAGAGGA GGGGAATAAC 
AAGTCACAGC AGCATGAGAG CACCAGCAGC TACAACTACA GGGTGGTCAA AGAGATTTTG 
ATCCGACTCA GCAAACTCTG TGTTCAAGAG AGCGCATCCG TGCGGAAGAG CAGGAAGCAG 
CAACAGCGCT TGCTCCGGAA CATGGGCGCC CACGCCGTGG TGCTGGAGCT GCTGCAGATC 
CCCTACGAGA AGGCTGAAGA CACCATGATG CAGGAGATAA TGAGGCTGGC TCATGAGTTT 
CTTCAGAATT TCTGCGCCGG CAACCACCCT AATCAGGCTC TGCTCCACAA ACATATTAAC 
CTGTTTCTAA ACCCAGGGAT CCTGGAAGCC GTCACGATGC AGCACATCTT CATGAACAAC 
TTCCAACTGT GCAGCGAGAT CAACGAGCGG GTCGTCCAGC ACTTTGTTCA CTGCATCGAG 
ACTCACGGTC GAAATGTCCA GTACATCAAG TTCCTGCAGA CGATTGTCAA GGCTGAAGGG 
AAATTCATCA AGAAGTGCCA AGACATGGTC ATGGCCGAGC TGGTTAATTC AGGAGAGGAT 
GTCCTCGTGT TCTACAACGA CAGAGCCTCT TTCCAGACCC TGATTCAGAT GATGAGGTCC 
GAGCGGGACC GGATGGACGA GAACAGCCCC CTCATGTACC ACATCCATCT GGTGGAGCTC 
TTGGCCGTGT GCACAGAGGG CAAGAACGTC TACACGGAGA TCAAATGCAA CTCCCTGCTC 
CCACTGGATG ACATTGTCCG CGTGGTGACC CACGAGGACT GCATCCCCGA GGTTAAAATT 
GCCTACATTA ACTTCCTGAA TCACTGCTAT GTGGACCCGG AAGTGGAAAT GAAGGAGATT 
TATACCAGCA ATCACATGTG GAAATTGTTT GAGAATTTCC TCGTCGACAT CTGCAGGGCC 
TGTAACAACA CGAGCGACAG GAAACACGCA GACTCGATTC TGGAGAAGTA CGTCACCGAA 
ATCGTCATGA GCATCGTCAC CACGTTCTTC AGTTCTCCCT TCTCAGACCA GAGTACAACT 
CTGCAGACTC GCCAGCCCGT CTTTGTGCAG CTTCTGCAAG GTGTGTTCCG GGTTTACCAC 
TGCAACTGGC TCATGCCAAG CCAGAAGGCC TCGGTGGAGA GCTGCATCCG GGTGCTCTCT 
GATGTAGCCA AGAGCCGGGC CATTGCCATT CCCGTGGACT TGGACAGTCA GGTCAACAAC 
CTCTTCCTCA AGTCCCACAA CCTCGTGCAG AAAACCGCCA TGAACTGGCG GCTGACGGCC 
CGCAATGCTG CCCGCAGAGA TTCTGTCCTG CCCGTTTCCA GGGACTACCG GAACATCATC 
GAGAGACTGC AGGACATTGT CTCGGCCCTG GAGGACCGTC TCCGGCCCCT GGTGCAGGCC 
GAGTTATCTG TGCTGGTGGA TGTCCTCCAC CGGCCCGAGC TGCTCTTCCC GGAGAACACG 
GACGCCAGGA GGAAGTGTGA AAGCGGGGGC TTCATCTGCA AGTTAATCAA ACACACTAAA 
CAGCTGCTGG AGGAGAATGA GGAGAAACTC TGCATCAAGG TCCTTCAGAC CCTCAGAGAA 
ATGATGACCA AAGACAGAGG CTATGGAGAA AAGGGTGAGG CCCTCAGGCA GATTTTGGTC 
AACCGTTACT ATGGAAACAT CAGACCTTCG GGAAGAAGAG AGAGCCTCAC GAGCTTTGGC 
AATGGCCCGC TGTCGCCAGG AGGACCCAGC AAGCCTGGGG GAGGAGGGGG AGGTTCCGGA 
TCCAGCCCCA TGAGCAGGGG TGAAATGAGC CTGGCCGAGG TTCAGTGCCA CCTTGACAAG 
GAGGGGGCCT CCAACCTGGT TATCGACCTC ATCATGAACG CATCCAGTGA CCGAGTGTTC 
CATGAAAGCA TTCTTCTAGC CATCGCCCTG CTGGAAGGAG GCAACACCAC CATACAGCAC 
TCCTTTTTCT GCCGGTTGAC AGAAGACAAG AAGTCAGAGA AATTCTTCAA GGTTTTCTAT 
GACCGAATGA AGGTGGCCCA GCAGGAAATC AAGGCAACAG TGACCGTGAA CACCAGTGAC 
TTGGGAAATA AAAAGAAAGA TGACGAGGTG GACAGGGATG CCCCGTCACG GAAAAAAGCC 
AAAGAGCCTG CGACGCAGAT TACGGAAGAG GTGCGGGATC AGCTCTTGGA GGCCTCTGCT 
GCCACCCGCA AAGCCTTCAC CACCTTCAGA AGGGAAGCTG ACCCCGACGA CCACTACCAG 
TCCGGGGAGG GCGCCCAGGC CGCGGCGGAC AAGAGCAAGG ACGACCTGGA GATGAGCGCG 
GTCATCACCA TCATGCAGCC CATCCTCCGC TTCCTGCAGC TGCTGTGCGA AAACCACAAC 
CGGGACCTCC AGAACTTCCT CCGTTGCCAA AACAACAAGA CCAACTACAA TTTGGTGTGC 
GAGACACTGC AGTTTCTGGA CTGTATTTGT GGAAGCACCA CCGGGGGTCT TGGTCTTCTG 
GGACTCTATA TCAACGAAAA GAACGTGGCC CTCATCAACC AAACCCTGGA AAGTTTGACT 
GAATACTGTC AAGGACCTTG CCATGAGAAT CAGAACTGCA TAGCCACCCA TGAATCCAAT 
GGCATTGACA TCATCACAGC CCTGATCCTC AATGACATCA ACCCTCTGGG AAAGAAAAGG 
ATGGACCTTG TGTTAGAACT GAAGAACAAT GCGTCCAAGT TGCTCCTGGC CATCATGGAG 
AGCAGGCATG ACAGTGAGAA TGCTGAGCGG ATCCTCTATA ACATGAGGCC CAAGGAACTG 
GTGGAAGTGA TCAAGAAAGC CTACATGCAA GGTGAAGTGG AGTTCGAGGA TGGTGAGAAT 
GGTGAGGACG GAGCTGCCTC CCCCAGAAAC GTGGGACACA ACATCTACAT CCTAGCTCAT 
CAGTTGGCTC GACATAACAA AGAACTTCAA ACCATGCTGA AACCCGGCGG GCAAGTGGAT 
GGAGACGAAA CTCTGGATTT TTATGCCCAG CCCACCGGCC CAAATGAGAT TGTCAGGTTA 
GACCGAACCA TGGAGCAGAT TGTCTTCCCC GTGCCCAGTA TATGTGAATT CCTAACCAAA 
GAGTCAAAAC TACGGATATA CTACACCACA GAGAGGGACG AGCAGGGCAG CAAGATCAAC 
GACTTCTTCC TGCGGTCCGA GGACCTCTTC AATGAGATGA ATTGGCAGAA GAAGCTCAGA 
GCCCAGCCCG TCCTGTACTG GTGCGCCCGC AACATGTCTT TCTGGAGTAG CATTTCATTC 
AACCTGGCCG TCCTGATGAA CCTGCTTGTG GCGTTTTTCT ACCCTTTTAA AGGAGTCCGA 
GGAGGGACCC TGGAACCGCA CTGGTCGGGA CTGCTGTGGA CGGCCATGCT CATCTCTCTG 
GCCATCGTCA TCGCCCTCCC CAAGCCCCAT GGCATCCGGG CCTTAATCGC TTCCACGATT 
CTCCGGTTGA TATTTTCCGT CGGGCTACAA CCCACGCTGT TTCTTTTGGG AGCTTTCAAC 
GTCTGCAATA AAATCATTTT TCTGATGAGC TTTGTGGGCA ACTGTGGGAC ATTCACCAGA 
GGCTACCGGG CCATGGTTCT GGATGTTGAG TTCCTTTATC ACCTGCTANA CCTGCTGATC 
TGCGCCATGG GGCTCTTCGT CCATGAGTTC TTCTACAGTT TGCTGCTTTT TGATTTAGTG 
TACAGAGAAG AGACTCTGCT CAATGTCATT AAAAGCGTCA CTCGCAACGG CCGGTCCATC 
ATCTTGATGG CGGTTCTGGC TTTGATCCTG GTTTACCTGT TCTCCATAGT GGGCTACCTT 
TTCTTCAAAG ATGACTTCAT CTTGGAAGTA GATAGGCTGC CCAATGAAAC CTCTCTTCCA 
GAAGCCAGCG AGAGTTTGGC AAGTGAGTTC CTGTACTCTG ACGTGTGTAG GGTGGAGACT 
GGGGAGAACT GCTCCTCTCC GGCACCCAAA GAAGAGCTGG TCCCTGCAGA AGAGACAGAG 
CAAGATAAAG AGCACACGTG CGAGACGCTG CTGATGTGCA TCGTCACGGT GCTGAGTCAC 
GGGCTGCGGA GCGGGGGCGG AGTGGGCGAT GTGCTCAGGA AGCCATCCAA AGAGGAGCCC 
CTCTTTGCTG CTCGAGTGAT CTATGACCTC TTGTTCTTCT TCATGGTCAT CATCATTGTC 
CTTAATCTGA TTTTTGGGGT CATCATTGAC ACCTTTGCCG ACCTGAGGAG TGAAAAACAG 
AAAAAAGAGG AGATATTAAA GACCACGTGC TTTATCTGCG GGTTGGAAAG AGACAAGTTT 
GACAACAAGA CCGTCACATT TGAAGAGCAC ATCAAGGAAG AACACAACAT GTGGCATTAC 
CTGTGCTTCA TCGTCCTGGT GAAAGTGAAG GACTCCACGG AGTACACAGG GCCCGAAAGT 
TACGTGGCAG AGATGATCAA GGAAAGAAAC CTAGACTGGT TCCCGAGGAT GAGAGCCATG 
TCCCTGGTCA GCAGCGATTC AGAAGGAGAG CAGAATGAGC TGAGGAACCT GCAGGAGAAG 
CTGGAGTCCA CCATGAAGCT TGTCACCAAC CTCTCTGGAC TGCTGTCAGA ATTAAAGGAT 
CAGATGACAG ATCAAAGGAA GCAGAAACAA AGAATGGGTC TTCTAGGACA TCCTCCTCAC 
ATCAATGTCA ACCCACAGCA ACCAGCATAA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

STIM1 positively regulates the Ca2+ release activity of the inositol 1,4,5-trisphosphate receptor in bovine aortic endothelial cells.
PloS one9(12)e114718(2014)
B?liveau ?,Lessard V,Guillemette G

Global dynamic conformational changes in the suppressor domain of IP3 receptor by stepwise binding of the two lobes of calmodulin.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology25(3)840-50(2011 Mar)
Kang S,Kwon H,Wen H,Song Y,Frueh D,Ahn HC,Yoo SH,Wagner G,Park S

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Effects of redox potential and Ca2+ on the inositol 1,4,5-trisphosphate receptor L3-1 loop region: implications for receptor regulation.
The Journal of biological chemistry283(37)25567-75(2008 Sep)
Kang S,Kang J,Kwon H,Frueh D,Yoo SH,Wagner G,Park S

A functional interaction between chromogranin B and the inositol 1,4,5-trisphosphate receptor/Ca2+ channel.
The Journal of biological chemistry278(50)49699-706(2003 Dec)
Thrower EC,Choe CU,So SH,Jeon SH,Ehrlich BE,Yoo SH

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ITPR1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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