Gene Symbol | UQCRFS1 |
Entrez Gene ID | 287020 |
Full Name | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
Synonyms | RISP |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
ORF » Species Summary » Bos taurus » UQCRFS1 cDNA ORF clone
Gene Symbol | UQCRFS1 |
Entrez Gene ID | 287020 |
Full Name | ubiquinol-cytochrome c reductase, Rieske iron-sulfur polypeptide 1 |
Synonyms | RISP |
Gene Type | protein-coding |
Organism | Bos taurus(cattle) |
mRNA | Protein | Name |
---|---|---|
NM_174813.2 | NP_777238.1 | cytochrome b-c1 complex subunit Rieske, mitochondrial precursor |
Danio rerio (zebrafish) | LOC100334857 | XP_003199036.1 |
Drosophila melanogaster (fruit fly) | RFeSP | NP_722715.1 |
Kluyveromyces lactis | KLLA0E22573g | XP_454973.1 |
Schizosaccharomyces pombe (fission yeast) | rip1 | NP_595941.1 |
Neurospora crassa | NCU06606 | XP_962348.1 |
Oryza sativa (rice) | Os04g0398500 | NP_001052672.1 |
Bos taurus (cattle) | UQCRFS1 | NP_777238.1 |
Mus musculus (house mouse) | Uqcrfs1 | NP_079986.1 |
UQCRFS1 | XP_001101289.1 | |
Canis lupus familiaris (dog) | UQCRFS1 | XP_533711.1 |
Rattus norvegicus (Norway rat) | Uqcrfs1 | NP_001008888.1 |
Gallus gallus (chicken) | UQCRFS1 | NP_001005843.1 |
Danio rerio (zebrafish) | uqcrfs1 | NP_001096664.1 |
Arabidopsis thaliana (thale cress) | AT5G13440 | NP_196848.1 |
Arabidopsis thaliana (thale cress) | AT5G13430 | NP_568288.1 |
Xenopus tropicalis (tropical clawed frog) | uqcrfs1 | NP_988911.1 |
Anopheles gambiae (African malaria mosquito) | AgaP_AGAP008955 | XP_319708.4 |
Caenorhabditis elegans (roundworm) | isp-1 | NP_501361.1 |
Eremothecium gossypii | AGOS_AEL067W | NP_984794.1 |
Magnaporthe oryzae (rice blast fungus) | MGG_16866 | XP_003712616.1 |
Homo sapiens (human) | UQCRFS1 | NP_005994.2 |
Pan troglodytes (chimpanzee) | UQCRFS1 | XP_001148728.1 |
Saccharomyces cerevisiae (baker's yeast) | RIP1 | NP_010890.3 |
Oryza sativa (rice) | Os02g0520800 | NP_001046975.1 |
The iron-sulfur cluster of the Rieske iron-sulfur protein functions as a proton-exiting gate in the cytochrome bc(1) complex.
Gurung B, Yu L, Xia D, Yu CA
The Journal of biological chemistry280(26)24895-902(2005 Jul)
Roles of the disulfide bond and adjacent residues in determining the reduction potentials and stabilities of respiratory-type Rieske clusters.
Leggate EJ, Hirst J
Biochemistry44(18)7048-58(2005 May)
Direct observation of redox-linked histidine protonation changes in the iron-sulfur protein of the cytochrome bc1 complex by ATR-FTIR spectroscopy.
Iwaki M, Yakovlev G, Hirst J, Osyczka A, Dutton PL, Marshall D, Rich PR
Biochemistry44(11)4230-7(2005 Mar)
Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex.
Iwata S, Lee JW, Okada K, Lee JK, Iwata M, Rasmussen B, Link TA, Ramaswamy S, Jap BK
Science (New York, N.Y.)281(5373)64-71(1998 Jul)
Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria.
Xia D, Yu CA, Kim H, Xia JZ, Kachurin AM, Zhang L, Yu L, Deisenhofer J
Science (New York, N.Y.)277(5322)60-6(1997 Jul)
GeneRIFs: Gene References Into Functions What's a GeneRIF?
in the normal catalytic cycle of the bc(1) complex, the [2Fe-2S] cluster may function as a proton-exiting gate
Title: The iron-sulfur cluster of the Rieske iron-sulfur protein functions as a proton-exiting gate in the cytochrome bc(1) complex.
Three hydrogen-bond mutant Rieske clusters all have decreased cluster reduction potentials and increased cluster pK values consistent with the removal of a hydrogen-bonding dipole, which preferentially stabilizes the most negatively charged state.
Title: Roles of the disulfide bond and adjacent residues in determining the reduction potentials and stabilities of respiratory-type Rieske clusters.
This is the first direct demonstration that histidine is the redox-linked protonation site of the Rieske iron-sulfur protein subunit of cytochrome bc1.
Title: Direct observation of redox-linked histidine protonation changes in the iron-sulfur protein of the cytochrome bc1 complex by ATR-FTIR spectroscopy.
The following UQCRFS1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the UQCRFS1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1+/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.
CloneID | OBa01231 | |
Clone ID Related Accession (Same CDS sequence) | NM_174813.2 | |
Accession Version | NM_174813.2 Latest version! | Documents for ORF clone product in default vector |
Sequence Information | ORF Nucleotide Sequence (Length: 810bp) Protein sequence SNP |
|
Vector | pcDNA3.1-C-(k)DYK or customized vector | User Manual |
Clone information | Clone Map | MSDS |
Tag on pcDNA3.1+/C-(K)DYK | C terminal DYKDDDDK tags | |
ORF Insert Method | CloneEZ™ Seamless cloning technology | |
Insert Structure | linear | |
Update Date | 2019-10-19 | |
Organism | Bos taurus(cattle) | |
Product | cytochrome b-c1 complex subunit Rieske, mitochondrial precursor | |
Comment | Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from M34336.1. On Jun 3, 2003 this sequence version replaced NM_174813.1. ##Evidence-Data-START## Transcript exon combination :: M34336.1, BC115994.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145445 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology ##RefSeq-Attributes-END## |
1 | ATGTTGTCGG TTGCCGCCCG CTCGCGCCAT TCGCGCCCGT CCTATCGGCC ACGTCCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
RefSeq | NP_777238.1 |
CDS | 16..825 |
Translation |
Target ORF information:
Target ORF information:
|
NM_174813.2 |
1 | ATGTTGTCGG TTGCCGCCCG CTCGCGCCAT TCGCGCCCGT CCTATCGGCC ACGTCCCGCG |
The stop codons will be deleted if pcDNA3.1+/C-(K)DYK vector is selected.
The iron-sulfur cluster of the Rieske iron-sulfur protein functions as a proton-exiting gate in the cytochrome bc(1) complex. |
Roles of the disulfide bond and adjacent residues in determining the reduction potentials and stabilities of respiratory-type Rieske clusters. |
Direct observation of redox-linked histidine protonation changes in the iron-sulfur protein of the cytochrome bc1 complex by ATR-FTIR spectroscopy. |
Complete structure of the 11-subunit bovine mitochondrial cytochrome bc1 complex. |
Crystal structure of the cytochrome bc1 complex from bovine heart mitochondria. |