GPX4 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	GPX4
Entrez Gene ID	286809
Full Name	glutathione peroxidase 4
Synonyms	PHGPx
Gene Type	protein-coding
Organism	Bos taurus(cattle)
Summary	The protein encoded by this gene belongs to the glutathione peroxidase family, members of which catalyze the reduction of hydrogen peroxide, organic hydroperoxides and lipid hydroperoxides, and thereby protect cells against oxidative damage. Several isozymes of this gene family exist in vertebrates, which vary in cellular location and substrate specificity. This isozyme has a high preference for lipid hydroperoxides and protects cells against membrane lipid peroxidation and cell death. It is also required for normal sperm development. Disruption of this gene in mouse spermatocytes is associated with male infertility. This isozyme is also a selenoprotein, containing the rare amino acid selenocysteine (Sec) at its active site. Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Oct 2016].

mRNA and Protein(s)

mRNA	Protein	Name
NM_174770.4	NP_777195.1	phospholipid hydroperoxide glutathione peroxidase isoform A precursor
NM_001346431.1	NP_001333360.1	phospholipid hydroperoxide glutathione peroxidase isoform C
NM_001346430.1	NP_001333359.1	phospholipid hydroperoxide glutathione peroxidase isoform B

Pathways from BioSystems

Homologies

Homo sapiens (human)	GPX4	NP_002076.2
Bos taurus (cattle)	GPX4	NP_777195.1
Caenorhabditis elegans (roundworm)	R03G5.5	NP_001123171.1
Danio rerio (zebrafish)	gpx4b	NP_001025241.2
Xenopus tropicalis (tropical clawed frog)	gpx4	XP_002937424.2
	GPX4	NP_001112361.1
Saccharomyces cerevisiae (baker's yeast)	GPX2	NP_009803.3
Rattus norvegicus (Norway rat)	Gpx4	NP_058861.3
Arabidopsis thaliana (thale cress)	GPX1	NP_180080.1
Arabidopsis thaliana (thale cress)	GPX7	NP_194915.2
Mus musculus (house mouse)	Gpx4	NP_001032830.2
Caenorhabditis elegans (roundworm)	T09A12.2	NP_001023368.1

Gene Ontology
Bibliography

Related articles in PubMed

Composition and evolution of the vertebrate and mammalian selenoproteomes.
Mariotti M, Ridge PG, Zhang Y, Lobanov AV, Pringle TH, Guigo R, Hatfield DL, Gladyshev VN
PloS one7(3)e33066(2012)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Estrogen selectively up-regulates the phospholipid hydroperoxide glutathione peroxidase in the oviducts.
Lapointe J, Kimmins S, Maclaren LA, Bilodeau JF
Endocrinology146(6)2583-92(2005 Jun)

Characterization of mammalian selenoproteomes.
Kryukov GV, Castellano S, Novoselov SV, Lobanov AV, Zehtab O, Guig? R, Gladyshev VN
Science (New York, N.Y.)300(5624)1439-43(2003 May)

Characterization of gene expression profiles in early bovine pregnancy using a custom cDNA microarray.
Ishiwata H, Katsuma S, Kizaki K, Patel OV, Nakano H, Takahashi T, Imai K, Hirasawa A, Shiojima S, Ikawa H, Suzuki Y, Tsujimoto G, Izaike Y, Todoroki J, Hashizume K
Molecular reproduction and development65(1)9-18(2003 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

GPx-4 has an important role in the physiological control of peroxide tone in the bordering cells of the oviductal lumen
Title: Estrogen selectively up-regulates the phospholipid hydroperoxide glutathione peroxidase in the oviducts.

The following GPX4 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the GPX4 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)
OBa41260	NM_174770.4 Latest version!	Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 1, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	7-9	$104.30 $149.00
OBa134039	NM_001346430.1 Latest version!	Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 2, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00
OBa134040	NM_001346431.1 Latest version!	Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 3, mRNA.	pcDNA3.1-C-(k)DYK or customized vector	TBD	$174.30 $249.00

ORF Online Only Promotion

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** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

GPX4 ( NM_174770.4 ) cDNA ORF clone, Bos taurus(cattle) -> NP_777195.1 Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 1, mRNA.

Price & Availability↑

CloneID	OBa41260
Clone ID Related Accession (Same CDS sequence)	NM_174770.4
Accession Version	NM_174770.4 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 594bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Bos taurus(cattle)
Product	phospholipid hydroperoxide glutathione peroxidase isoform A precursor
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from DT839524.1, BC102957.1 and DV828741.1. On Oct 11, 2016 this sequence version replaced NM_174770.3. Transcript Variant: This variant (1) represents the predominant transcript and encodes the canonical isoform A. A similar isoform in rat has been shown to be localized to the mitochondria (PMID:9988735). ##Evidence-Data-START## Transcript exon combination :: DT839524.1, DT843234.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145412, SAMN03145413 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGAGCTTTA GCCGTCTGTA CCGCCTGCTC AAGCCAGCGC TACTCTGCGG GGCTCTGGCT 
GCGCCGGGCC TGGCCAGCAC CATGTGCGCG TCCCGCGACG ACTGGCGCTG TGCTCGCTCC 
ATGCACGAAT TTTCAGCCAA GGACATCGAC GGGCGCATGG TTAACCTGGA CAAGTACCGG 
GGCCACGTGT GCATCGTCAC CAATGTGGCC TCGCAATGAG GCAAGACTGA CGTAAACTAC 
ACTCAGCTGG TCGACCTGCA CGCCCGATAC GCCGAGTGTG GTTTACGGAT CCTGGCCTTC 
CCTTGCAACC AGTTTGGGAG GCAGGAGCCA GGGAGTAATG CAGAGATCAA AGAGTTCGCC 
GCTGGCTATA ACGTCAAATT CGATTTGTTC AGCAAGATCT GTGTAAATGG GGACGACGCC 
CACCCTCTGT GGAAATGGAT GAAAGTCCAG CCCAAGGGGA GAGGCATGCT GGGAAACGCC 
ATCAAATGGA ACTTCACCAA GTTCCTCATT GACAAGAACG GCTGTGTGGT GAAGCGGTAT 
GGTCCCATGG AAGAGCCCCT GGTGATAGAG AAGGACCTGC CGTGCTACCT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_777195.1
CDS	117..710
Translation	MSFSRLYRLLKPALLCGALAAPGLASTMCASRDDWRCARSMHEFSAKDIDGRMVNLDKYRGHVCIVTNVASQ*GKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSNAEIKEFAAGYNVKFDLFSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPCYL

Target ORF information:

RefSeq Version	NM_174770.4
Organism	Bos taurus(cattle)
Definition	Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 1, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_174770.4

ORF Insert Sequence:

ATGAGCTTTA GCCGTCTGTA CCGCCTGCTC AAGCCAGCGC TACTCTGCGG GGCTCTGGCT 
GCGCCGGGCC TGGCCAGCAC CATGTGCGCG TCCCGCGACG ACTGGCGCTG TGCTCGCTCC 
ATGCACGAAT TTTCAGCCAA GGACATCGAC GGGCGCATGG TTAACCTGGA CAAGTACCGG 
GGCCACGTGT GCATCGTCAC CAATGTGGCC TCGCAATGAG GCAAGACTGA CGTAAACTAC 
ACTCAGCTGG TCGACCTGCA CGCCCGATAC GCCGAGTGTG GTTTACGGAT CCTGGCCTTC 
CCTTGCAACC AGTTTGGGAG GCAGGAGCCA GGGAGTAATG CAGAGATCAA AGAGTTCGCC 
GCTGGCTATA ACGTCAAATT CGATTTGTTC AGCAAGATCT GTGTAAATGG GGACGACGCC 
CACCCTCTGT GGAAATGGAT GAAAGTCCAG CCCAAGGGGA GAGGCATGCT GGGAAACGCC 
ATCAAATGGA ACTTCACCAA GTTCCTCATT GACAAGAACG GCTGTGTGGT GAAGCGGTAT 
GGTCCCATGG AAGAGCCCCT GGTGATAGAG AAGGACCTGC CGTGCTACCT CTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPX4 ( NM_001346430.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001333359.1 Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 2, mRNA.

Price & Availability↑

CloneID	OBa134039
Clone ID Related Accession (Same CDS sequence)	NM_001346430.1
Accession Version	NM_001346430.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 723bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Bos taurus(cattle)
Product	phospholipid hydroperoxide glutathione peroxidase isoform B
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EV607600.1, DT835990.1 and DV828741.1. Transcript Variant: This variant (2) contains an alternate 5' terminal exon compared to variant 1. The resulting isoform (B) has a longer and a distinct N-terminus compared to isoform A. ##Evidence-Data-START## Transcript exon combination :: DT835990.1, EH126297.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145414, SAMN03145431 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCCGCG CAGCCGCCTG CTCCCCGGGC CGTCGAGGGC AGCGGCGCCG CTTGCCGGCC 
GGGCGACGGC GCCGAGCCCC CCGAAGGAGG AGGGCTCGGA TATGCCGTCG CAGGAGGGCG 
CGCCCCCGGC GGAGGAGGCC AGCTCCTGAG AGCCCTGGGC TGGCGGGACC CCCGGCCGGG 
GAGAGCGGCT GCGCCACCGA ATCCCAAGAC CCGTGCGCGT CCCGCGACGA CTGGCGCTGT 
GCTCGCTCCA TGCACGAATT TTCAGCCAAG GACATCGACG GGCGCATGGT TAACCTGGAC 
AAGTACCGGG GCCACGTGTG CATCGTCACC AATGTGGCCT CGCAATGAGG CAAGACTGAC 
GTAAACTACA CTCAGCTGGT CGACCTGCAC GCCCGATACG CCGAGTGTGG TTTACGGATC 
CTGGCCTTCC CTTGCAACCA GTTTGGGAGG CAGGAGCCAG GGAGTAATGC AGAGATCAAA 
GAGTTCGCCG CTGGCTATAA CGTCAAATTC GATTTGTTCA GCAAGATCTG TGTAAATGGG 
GACGACGCCC ACCCTCTGTG GAAATGGATG AAAGTCCAGC CCAAGGGGAG AGGCATGCTG 
GGAAACGCCA TCAAATGGAA CTTCACCAAG TTCCTCATTG ACAAGAACGG CTGTGTGGTG 
AAGCGGTATG GTCCCATGGA AGAGCCCCTG GTGATAGAGA AGGACCTGCC GTGCTACCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001333359.1
CDS	59..781
Translation	MGRAAACSPGRRGQRRRLPAGRRRRAPRRRRARICRRRRARPRRRRPAPESPGLAGPPAGESGCATESQDPCASRDDWRCARSMHEFSAKDIDGRMVNLDKYRGHVCIVTNVASQ*GKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSNAEIKEFAAGYNVKFDLFSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPCYL

Target ORF information:

RefSeq Version	NM_001346430.1
Organism	Bos taurus(cattle)
Definition	Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 2, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001346430.1

ORF Insert Sequence:

ATGGGCCGCG CAGCCGCCTG CTCCCCGGGC CGTCGAGGGC AGCGGCGCCG CTTGCCGGCC 
GGGCGACGGC GCCGAGCCCC CCGAAGGAGG AGGGCTCGGA TATGCCGTCG CAGGAGGGCG 
CGCCCCCGGC GGAGGAGGCC AGCTCCTGAG AGCCCTGGGC TGGCGGGACC CCCGGCCGGG 
GAGAGCGGCT GCGCCACCGA ATCCCAAGAC CCGTGCGCGT CCCGCGACGA CTGGCGCTGT 
GCTCGCTCCA TGCACGAATT TTCAGCCAAG GACATCGACG GGCGCATGGT TAACCTGGAC 
AAGTACCGGG GCCACGTGTG CATCGTCACC AATGTGGCCT CGCAATGAGG CAAGACTGAC 
GTAAACTACA CTCAGCTGGT CGACCTGCAC GCCCGATACG CCGAGTGTGG TTTACGGATC 
CTGGCCTTCC CTTGCAACCA GTTTGGGAGG CAGGAGCCAG GGAGTAATGC AGAGATCAAA 
GAGTTCGCCG CTGGCTATAA CGTCAAATTC GATTTGTTCA GCAAGATCTG TGTAAATGGG 
GACGACGCCC ACCCTCTGTG GAAATGGATG AAAGTCCAGC CCAAGGGGAG AGGCATGCTG 
GGAAACGCCA TCAAATGGAA CTTCACCAAG TTCCTCATTG ACAAGAACGG CTGTGTGGTG 
AAGCGGTATG GTCCCATGGA AGAGCCCCTG GTGATAGAGA AGGACCTGCC GTGCTACCTC 
TAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

GPX4 ( NM_001346431.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001333360.1 Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 3, mRNA.

Price & Availability↑

CloneID	OBa134040
Clone ID Related Accession (Same CDS sequence)	NM_001346431.1
Accession Version	NM_001346431.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 765bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-11-15
Organism	Bos taurus(cattle)
Product	phospholipid hydroperoxide glutathione peroxidase isoform C
Comment	Comment: REVIEWED REFSEQ: This record has been curated by NCBI staff. The reference sequence was derived from EV607600.1, EH125462.1 and DV828741.1. Transcript Variant: This variant (3) contains an alternate 5' terminal exon compared to variant 1. The resulting isoform (C) has a longer and a distinct N-terminus compared to isoform A. ##Evidence-Data-START## Transcript exon combination :: EH124949.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145433 [ECO:0000348] ##Evidence-Data-END## ##RefSeq-Attributes-START## gene product(s) localized to mito. :: inferred from homology protein contains selenocysteine :: inferred from conservation ##RefSeq-Attributes-END## COMPLETENESS: complete on the 3' end.

ATGGGCCGCG CAGCCGCCTG CTCCCCGGGC CGTCGAGGGC AGCGGCGCCG CTTGCCGGCC 
GGGCGACGGC GCCGAGCCCC CCGAAGGAGG AGGGCTCGGA TATGCCGTCG CAGGAGGGCG 
CGCCCCCGGC GGAGGAGGCC AGCTCCTGAG AGCCCTGGGC TGGCGGGACC CCCGGCCGGG 
GAGAGCGGCT GCGCCACCGA ATCCCAAGAC CCGGTGCGCA CGGAGGCCCC CACACCCAGC 
GGCCTCCCCC ATCCGTGCGC GTCCCGCGAC GACTGGCGCT GTGCTCGCTC CATGCACGAA 
TTTTCAGCCA AGGACATCGA CGGGCGCATG GTTAACCTGG ACAAGTACCG GGGCCACGTG 
TGCATCGTCA CCAATGTGGC CTCGCAATGA GGCAAGACTG ACGTAAACTA CACTCAGCTG 
GTCGACCTGC ACGCCCGATA CGCCGAGTGT GGTTTACGGA TCCTGGCCTT CCCTTGCAAC 
CAGTTTGGGA GGCAGGAGCC AGGGAGTAAT GCAGAGATCA AAGAGTTCGC CGCTGGCTAT 
AACGTCAAAT TCGATTTGTT CAGCAAGATC TGTGTAAATG GGGACGACGC CCACCCTCTG 
TGGAAATGGA TGAAAGTCCA GCCCAAGGGG AGAGGCATGC TGGGAAACGC CATCAAATGG 
AACTTCACCA AGTTCCTCAT TGACAAGAAC GGCTGTGTGG TGAAGCGGTA TGGTCCCATG 
GAAGAGCCCC TGGTGATAGA GAAGGACCTG CCGTGCTACC TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001333360.1
CDS	59..823
Translation	MGRAAACSPGRRGQRRRLPAGRRRRAPRRRRARICRRRRARPRRRRPAPESPGLAGPPAGESGCATESQDPVRTEAPTPSGLPHPCASRDDWRCARSMHEFSAKDIDGRMVNLDKYRGHVCIVTNVASQ*GKTDVNYTQLVDLHARYAECGLRILAFPCNQFGRQEPGSNAEIKEFAAGYNVKFDLFSKICVNGDDAHPLWKWMKVQPKGRGMLGNAIKWNFTKFLIDKNGCVVKRYGPMEEPLVIEKDLPCYL

Target ORF information:

RefSeq Version	NM_001346431.1
Organism	Bos taurus(cattle)
Definition	Bos taurus glutathione peroxidase 4 (GPX4), transcript variant 3, mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001346431.1

ORF Insert Sequence:

ATGGGCCGCG CAGCCGCCTG CTCCCCGGGC CGTCGAGGGC AGCGGCGCCG CTTGCCGGCC 
GGGCGACGGC GCCGAGCCCC CCGAAGGAGG AGGGCTCGGA TATGCCGTCG CAGGAGGGCG 
CGCCCCCGGC GGAGGAGGCC AGCTCCTGAG AGCCCTGGGC TGGCGGGACC CCCGGCCGGG 
GAGAGCGGCT GCGCCACCGA ATCCCAAGAC CCGGTGCGCA CGGAGGCCCC CACACCCAGC 
GGCCTCCCCC ATCCGTGCGC GTCCCGCGAC GACTGGCGCT GTGCTCGCTC CATGCACGAA 
TTTTCAGCCA AGGACATCGA CGGGCGCATG GTTAACCTGG ACAAGTACCG GGGCCACGTG 
TGCATCGTCA CCAATGTGGC CTCGCAATGA GGCAAGACTG ACGTAAACTA CACTCAGCTG 
GTCGACCTGC ACGCCCGATA CGCCGAGTGT GGTTTACGGA TCCTGGCCTT CCCTTGCAAC 
CAGTTTGGGA GGCAGGAGCC AGGGAGTAAT GCAGAGATCA AAGAGTTCGC CGCTGGCTAT 
AACGTCAAAT TCGATTTGTT CAGCAAGATC TGTGTAAATG GGGACGACGC CCACCCTCTG 
TGGAAATGGA TGAAAGTCCA GCCCAAGGGG AGAGGCATGC TGGGAAACGC CATCAAATGG 
AACTTCACCA AGTTCCTCAT TGACAAGAAC GGCTGTGTGG TGAAGCGGTA TGGTCCCATG 
GAAGAGCCCC TGGTGATAGA GAAGGACCTG CCGTGCTACC TCTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Composition and evolution of the vertebrate and mammalian selenoproteomes.
PloS one7(3)e33066(2012)
Mariotti M,Ridge PG,Zhang Y,Lobanov AV,Pringle TH,Guigo R,Hatfield DL,Gladyshev VN

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Estrogen selectively up-regulates the phospholipid hydroperoxide glutathione peroxidase in the oviducts.
Endocrinology146(6)2583-92(2005 Jun)
Lapointe J,Kimmins S,Maclaren LA,Bilodeau JF

Characterization of mammalian selenoproteomes.
Science (New York, N.Y.)300(5624)1439-43(2003 May)
Kryukov GV,Castellano S,Novoselov SV,Lobanov AV,Zehtab O,Guig? R,Gladyshev VN

Characterization of gene expression profiles in early bovine pregnancy using a custom cDNA microarray.
Molecular reproduction and development65(1)9-18(2003 May)
Ishiwata H,Katsuma S,Kizaki K,Patel OV,Nakano H,Takahashi T,Imai K,Hirasawa A,Shiojima S,Ikawa H,Suzuki Y,Tsujimoto G,Izaike Y,Todoroki J,Hashizume K

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GPX4 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

Target ORF information:

Target ORF information:

ORF Insert Sequence:

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