CDH1 cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	CDH1
Entrez Gene ID	282637
Full Name	cadherin 1
General protein information	Preferred Names cadherin 1 Names cadherin-1 E-cadherin cadherin 1, type 1, E-cadherin (epithelial) epithelial cadherin
Gene Type	protein-coding
Organism	Bos taurus(cattle)

mRNA and Protein(s)

mRNA	Protein	Name
NM_001002763.1	NP_001002763.1	cadherin-1 precursor

Pathways from BioSystems

Homologies

	CDH1	XP_002802562.1
Rattus norvegicus (Norway rat)	Cdh1	NP_112624.1
Danio rerio (zebrafish)	cdh1	NP_571895.1
Homo sapiens (human)	CDH1	NP_004351.1
Danio rerio (zebrafish)	LOC568392	XP_696808.4
Canis lupus familiaris (dog)	CDH1	XP_536807.3
Xenopus tropicalis (tropical clawed frog)	LOC100485633	XP_002936044.1
Bos taurus (cattle)	CDH1	NP_001002763.1
Gallus gallus (chicken)	CDH1	NP_001034347.2
Danio rerio (zebrafish)	si:dkey-173l11.3	XP_005166659.1
Pan troglodytes (chimpanzee)	CDH1	XP_001168150.1
Mus musculus (house mouse)	Cdh1	NP_033994.1
Danio rerio (zebrafish)	si:ch211-206i14.2	XP_695998.5
Danio rerio (zebrafish)	si:busm1-71b9.3	XP_005166660.1

Gene Ontology
Bibliography

Related articles in PubMed

Gene silencing in bovine zygotes: siRNA transfection versus microinjection.
O'Meara CM, Murray JD, Mamo S, Gallagher E, Roche J, Lonergan P
Reproduction, fertility, and development23(4)534-43(2011)

A whole-genome assembly of the domestic cow, Bos taurus.
Zimin AV, Delcher AL, Florea L, Kelley DR, Schatz MC, Puiu D, Hanrahan F, Pertea G, Van Tassell CP, Sonstegard TS, Mar?ais G, Roberts M, Subramanian P, Yorke JA, Salzberg SL
Genome biology10(4)R42(2009)

Suppression of connexin 43 and E-cadherin transcripts in in vitro derived bovine embryos following culture in vitro or in vivo in the homologous bovine oviduct.
Tesfaye D, Lonergan P, Hoelker M, Rings F, Nganvongpanit K, Havlicek V, Besenfelder U, Jennen D, Tholen E, Schellander K
Molecular reproduction and development74(8)978-88(2007 Aug)

The cytoplasmic expression of E-cadherin and beta-catenin in bovine trophoblasts during binucleate cell differentiation.
Nakano H, Shimada A, Imai K, Takahashi T, Hashizume K
Placenta26(5)393-401(2005 May)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Transfection of zygotes with 100 and 200 nM E-cadherin siRNA led to a 72 and 38% reduction, respectively, in E-cadherin mRNA relative abundance in Day 7 blastocysts compared with controls.
Title: Gene silencing in bovine zygotes: siRNA transfection versus microinjection.

Results describe the effect of suppression of connexin 43 and E-cadherin on the development, mRNA and protein expression of bovine blastocysts cultured in vitro or in vivo.
Title: Suppression of connexin 43 and E-cadherin transcripts in in vitro derived bovine embryos following culture in vitro or in vivo in the homologous bovine oviduct.

E-cadherin and beta-catenin were distributed not only at the cell to cell boundary but throughout the cytoplasm in binucleate trophoblast cells
Title: The cytoplasmic expression of E-cadherin and beta-catenin in bovine trophoblasts during binucleate cell differentiation.

The following CDH1 gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the CDH1 cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41697	NM_001002763.1 Latest version!	Bos taurus cadherin 1 (CDH1), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$510.30 $729.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

CDH1 ( NM_001002763.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001002763.1 Bos taurus cadherin 1 (CDH1), mRNA.

Price & Availability↑

CloneID	OBa41697
Clone ID Related Accession (Same CDS sequence)	NM_001002763.1
Accession Version	NM_001002763.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2649bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-12-24
Organism	Bos taurus(cattle)
Product	cadherin-1 precursor
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from AY508164.1. ##Evidence-Data-START## Transcript exon combination :: AY508164.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145414 [ECO:0000348] ##Evidence-Data-END##

ATGGGCCCTT GGAGCCGCAG CCTCTCTGCG CTCTGCTGCT GCTGCAGGTG TAATCCGTGG 
CTCTGCCGGG AGCCGGAGCC CTGCATTCCT GGCTTTGGTG CTGAGAGTTA CACGTTCACC 
GTGCCCCGGC GGAACTTGGA GAGAGGGCGA GTCCTAGGCA GAGTGAGTTT TGAAGGATGT 
GCTGGCCTAC CAAGGACAGT CTATGTTTCT GATGACACCC GATTCAAAGT GCACACAGAT 
GGCGTGCTTA CAGTCAGACG ACCTGTACAC CTTCATCGTC CAGAGCTAAG TTTTCTTGTC 
CATGCCTGGG ACTCCACCCA CAGGAAGCTC TCCACCAAAG TGACACTGGA GGTATCAGCG 
CACCACCACC ACCACCACAG TCATCATGAC TCTCCCTCTG GAACCCAGAC AGAAGTGCTC 
ACATTTCCTG GCCCCCACCA TGGTCTCAGG AGACAGAAGA GAGACTGGGT TATTCCTCCT 
ATCAGCTGCC CAGAAAATGA GAAAGGCCCA TTTCCTAAGT CGCTGGTCCA GATCAAATCT 
AACAAGGAGA AAGAAACCCA AGTTTTCTAC AGCATCACTG GCCAACGAGC TGATACACCC 
CCTGTCGGTG TTTTTATTAT TGAAAGAGAA ACAGGATGGT TAAAAGTGAC ACAGCCTCTG 
GATAGAGAAC AGATTGCCAA GTACATTCTC TTCTCTCATG CCGTGTCTTC AAATGGACAA 
GCCATTGAAG AGCCTATGGA GATTGTGATC ACCGTGACCG ACCAGAATGA CAACAAGCCC 
CAGTTCACCC AGGAGGTCTT CAAGGCGTCT GCCCTGGAAG GCGCTCTTCC AGGAACCTCT 
GTGATGCAGG TCACGGCCAC AGATATAGAT GACGAGGTGA ACACCTACAC CGCTGCCATC 
GGTTACACAA TCCCAGCCCA AGATCCCATG CTGCCGCACA ACAAAATGTT CACCATCAAC 
AAGGAAACAG GCGTCATCAG TGTGCTCACC ACCGGGCTGG ACCGTGAGAG TTTTCCCACA 
TACACCCTGA TGGTCCAAGC AGCAGACCTT AACGGCGAAG GCTTGAGCAC AACTGCAACG 
GCCGTGATCA CAGTCTTGGA CACCAATGAT AATGCTCCCA GATTCAACCC AACCACGTAC 
GTGGGGTCGG TGCCTGAGAA CGAGGCTAAT GTGGCCATCA CCACACTCAC AGTGACTGAT 
GCCGACGACC CCAACACCCC GGCATGGGAG GCTGTTTACA CAGTATTAAA TGATAACGAG 
AAGCAATTTA TCGTCGTCAC AGACCCAGTC ACCAATGAAG GCACTCTGAA AACAGCTAAG 
GGCTTGGATT TTGAGGCCAA GCAGCAGTAC ATCCTGTACG TGGCAGTGAC AAATGTGGCC 
CCCTTTGAAG TCACTCTCCC CACTTCCACA GCCACCGTCA CTGTGGATGT GATAGATGTG 
AATGAAGCCC CCATCTTTGT GCCTCCTCAA AAGAGAGTGG AAGTGCCCGA GGACTTTGGC 
GTGGGCCTGG AGATCACATC CTATACTGCC CGGGAGCCAG ACACATTTAT GGAACAGAAG 
ATCACGTATC GGATTTGGAG GGACACTGCC AACTGGCTGG AGATTAATCC AGAAACGGGT 
GCCATTTCCA CTCGGGCTGA GTTGGACAGA GAGGATGTCG ATCATGTGAA GAACAGCACG 
TACACGGCCC TCATTATAGC CACTGACAAT GGTTCTCCAC CTGCCACTGG GACAGGCACC 
CTGCTCTTGT TCCTCGATGA TGTGAATGAC AATGGCCCCG TACCAGAACC CCGGACCATG 
GACTTCTGCC AGAGGAATCC TGAGCCTCAT ATCATCAACA TCAATGATCC TGATCTCCCT 
CCGAACACCT CCCCCTTTAC AGCAGAACTG ACACATGGGG CGAGTGTCAA TTGGACCATT 
GAGTACAATG ACCAAGAACG TGAGTCTCTG ATTTTGAAGC CAAAGAAAAC CTTAGAGCTG 
GGTGACCACA AAATCAATCT CAAGCTCATA GACAACCAGA ACAAAGACCA GGTGACCACA 
CTTGATGTGC ACGTGTGTGA CTGTGATGGG ATCGTCAGCA ACTGCAGGAA GGCACGGCCT 
GCTGAAGCAG GATTGCAAGT TCCCGCCATC CTGGGGATCC TTGGAGGCAT CCTTGCTTTT 
CTGATCCTTA TTTTGCTGCT TCTGCTACTT GTTCGGAGGA GAAGGGTGGT CAAAGAGCCC 
TTACTGCCCC CAGAAGATGA CACCCGGGAC AATGTGTATT ACTATGATGA AGAAGGAGGT 
GGAGAAGAAG ATCAGGACTT TGACTTGAGC CAGTTACATA GGGGCCTGGA TGCTCGGCCT 
GAAGTGACTC GCAATGACGT GGCACCAACC CTCATGAGTG TGCCCCAGTA CCGACCCCGC 
CCTGCCAATC CTGATGAAAT TGGAAACTTT ATTGATGAAA ACCTGAAGGC AGCTGATAGT 
GACCCCACTG CCCCACCCTA TGACTCTCTG CTGGTGTTTG ATTATGAAGG AAGTGGTTCC 
GAAGCTGCTA CTCTGAGCTC CCTGAACTCC TCAGAGTCAG ACCAAGACCA GGACTATGAC 
TACCTGAATG AATGGGGCAA TCGCTTCAAG AAGCTGGCGG ACATGTATGG AGGCGGCGAG 
GACGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001002763.1
CDS	1..2649
Translation	MGPWSRSLSALCCCCRCNPWLCREPEPCIPGFGAESYTFTVPRRNLERGRVLGRVSFEGCAGLPRTVYVSDDTRFKVHTDGVLTVRRPVHLHRPELSFLVHAWDSTHRKLSTKVTLEVSAHHHHHHSHHDSPSGTQTEVLTFPGPHHGLRRQKRDWVIPPISCPENEKGPFPKSLVQIKSNKEKETQVFYSITGQRADTPPVGVFIIERETGWLKVTQPLDREQIAKYILFSHAVSSNGQAIEEPMEIVITVTDQNDNKPQFTQEVFKASALEGALPGTSVMQVTATDIDDEVNTYTAAIGYTIPAQDPMLPHNKMFTINKETGVISVLTTGLDRESFPTYTLMVQAADLNGEGLSTTATAVITVLDTNDNAPRFNPTTYVGSVPENEANVAITTLTVTDADDPNTPAWEAVYTVLNDNEKQFIVVTDPVTNEGTLKTAKGLDFEAKQQYILYVAVTNVAPFEVTLPTSTATVTVDVIDVNEAPIFVPPQKRVEVPEDFGVGLEITSYTAREPDTFMEQKITYRIWRDTANWLEINPETGAISTRAELDREDVDHVKNSTYTALIIATDNGSPPATGTGTLLLFLDDVNDNGPVPEPRTMDFCQRNPEPHIININDPDLPPNTSPFTAELTHGASVNWTIEYNDQERESLILKPKKTLELGDHKINLKLIDNQNKDQVTTLDVHVCDCDGIVSNCRKARPAEAGLQVPAILGILGGILAFLILILLLLLLVRRRRVVKEPLLPPEDDTRDNVYYYDEEGGGEEDQDFDLSQLHRGLDARPEVTRNDVAPTLMSVPQYRPRPANPDEIGNFIDENLKAADSDPTAPPYDSLLVFDYEGSGSEAATLSSLNSSESDQDQDYDYLNEWGNRFKKLADMYGGGEDD

Target ORF information:

RefSeq Version	NM_001002763.1
Organism	Bos taurus(cattle)
Definition	Bos taurus cadherin 1 (CDH1), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001002763.1

ORF Insert Sequence:

ATGGGCCCTT GGAGCCGCAG CCTCTCTGCG CTCTGCTGCT GCTGCAGGTG TAATCCGTGG 
CTCTGCCGGG AGCCGGAGCC CTGCATTCCT GGCTTTGGTG CTGAGAGTTA CACGTTCACC 
GTGCCCCGGC GGAACTTGGA GAGAGGGCGA GTCCTAGGCA GAGTGAGTTT TGAAGGATGT 
GCTGGCCTAC CAAGGACAGT CTATGTTTCT GATGACACCC GATTCAAAGT GCACACAGAT 
GGCGTGCTTA CAGTCAGACG ACCTGTACAC CTTCATCGTC CAGAGCTAAG TTTTCTTGTC 
CATGCCTGGG ACTCCACCCA CAGGAAGCTC TCCACCAAAG TGACACTGGA GGTATCAGCG 
CACCACCACC ACCACCACAG TCATCATGAC TCTCCCTCTG GAACCCAGAC AGAAGTGCTC 
ACATTTCCTG GCCCCCACCA TGGTCTCAGG AGACAGAAGA GAGACTGGGT TATTCCTCCT 
ATCAGCTGCC CAGAAAATGA GAAAGGCCCA TTTCCTAAGT CGCTGGTCCA GATCAAATCT 
AACAAGGAGA AAGAAACCCA AGTTTTCTAC AGCATCACTG GCCAACGAGC TGATACACCC 
CCTGTCGGTG TTTTTATTAT TGAAAGAGAA ACAGGATGGT TAAAAGTGAC ACAGCCTCTG 
GATAGAGAAC AGATTGCCAA GTACATTCTC TTCTCTCATG CCGTGTCTTC AAATGGACAA 
GCCATTGAAG AGCCTATGGA GATTGTGATC ACCGTGACCG ACCAGAATGA CAACAAGCCC 
CAGTTCACCC AGGAGGTCTT CAAGGCGTCT GCCCTGGAAG GCGCTCTTCC AGGAACCTCT 
GTGATGCAGG TCACGGCCAC AGATATAGAT GACGAGGTGA ACACCTACAC CGCTGCCATC 
GGTTACACAA TCCCAGCCCA AGATCCCATG CTGCCGCACA ACAAAATGTT CACCATCAAC 
AAGGAAACAG GCGTCATCAG TGTGCTCACC ACCGGGCTGG ACCGTGAGAG TTTTCCCACA 
TACACCCTGA TGGTCCAAGC AGCAGACCTT AACGGCGAAG GCTTGAGCAC AACTGCAACG 
GCCGTGATCA CAGTCTTGGA CACCAATGAT AATGCTCCCA GATTCAACCC AACCACGTAC 
GTGGGGTCGG TGCCTGAGAA CGAGGCTAAT GTGGCCATCA CCACACTCAC AGTGACTGAT 
GCCGACGACC CCAACACCCC GGCATGGGAG GCTGTTTACA CAGTATTAAA TGATAACGAG 
AAGCAATTTA TCGTCGTCAC AGACCCAGTC ACCAATGAAG GCACTCTGAA AACAGCTAAG 
GGCTTGGATT TTGAGGCCAA GCAGCAGTAC ATCCTGTACG TGGCAGTGAC AAATGTGGCC 
CCCTTTGAAG TCACTCTCCC CACTTCCACA GCCACCGTCA CTGTGGATGT GATAGATGTG 
AATGAAGCCC CCATCTTTGT GCCTCCTCAA AAGAGAGTGG AAGTGCCCGA GGACTTTGGC 
GTGGGCCTGG AGATCACATC CTATACTGCC CGGGAGCCAG ACACATTTAT GGAACAGAAG 
ATCACGTATC GGATTTGGAG GGACACTGCC AACTGGCTGG AGATTAATCC AGAAACGGGT 
GCCATTTCCA CTCGGGCTGA GTTGGACAGA GAGGATGTCG ATCATGTGAA GAACAGCACG 
TACACGGCCC TCATTATAGC CACTGACAAT GGTTCTCCAC CTGCCACTGG GACAGGCACC 
CTGCTCTTGT TCCTCGATGA TGTGAATGAC AATGGCCCCG TACCAGAACC CCGGACCATG 
GACTTCTGCC AGAGGAATCC TGAGCCTCAT ATCATCAACA TCAATGATCC TGATCTCCCT 
CCGAACACCT CCCCCTTTAC AGCAGAACTG ACACATGGGG CGAGTGTCAA TTGGACCATT 
GAGTACAATG ACCAAGAACG TGAGTCTCTG ATTTTGAAGC CAAAGAAAAC CTTAGAGCTG 
GGTGACCACA AAATCAATCT CAAGCTCATA GACAACCAGA ACAAAGACCA GGTGACCACA 
CTTGATGTGC ACGTGTGTGA CTGTGATGGG ATCGTCAGCA ACTGCAGGAA GGCACGGCCT 
GCTGAAGCAG GATTGCAAGT TCCCGCCATC CTGGGGATCC TTGGAGGCAT CCTTGCTTTT 
CTGATCCTTA TTTTGCTGCT TCTGCTACTT GTTCGGAGGA GAAGGGTGGT CAAAGAGCCC 
TTACTGCCCC CAGAAGATGA CACCCGGGAC AATGTGTATT ACTATGATGA AGAAGGAGGT 
GGAGAAGAAG ATCAGGACTT TGACTTGAGC CAGTTACATA GGGGCCTGGA TGCTCGGCCT 
GAAGTGACTC GCAATGACGT GGCACCAACC CTCATGAGTG TGCCCCAGTA CCGACCCCGC 
CCTGCCAATC CTGATGAAAT TGGAAACTTT ATTGATGAAA ACCTGAAGGC AGCTGATAGT 
GACCCCACTG CCCCACCCTA TGACTCTCTG CTGGTGTTTG ATTATGAAGG AAGTGGTTCC 
GAAGCTGCTA CTCTGAGCTC CCTGAACTCC TCAGAGTCAG ACCAAGACCA GGACTATGAC 
TACCTGAATG AATGGGGCAA TCGCTTCAAG AAGCTGGCGG ACATGTATGG AGGCGGCGAG 
GACGACTAG

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Gene silencing in bovine zygotes: siRNA transfection versus microinjection.
Reproduction, fertility, and development23(4)534-43(2011)
O'Meara CM,Murray JD,Mamo S,Gallagher E,Roche J,Lonergan P

A whole-genome assembly of the domestic cow, Bos taurus.
Genome biology10(4)R42(2009)
Zimin AV,Delcher AL,Florea L,Kelley DR,Schatz MC,Puiu D,Hanrahan F,Pertea G,Van Tassell CP,Sonstegard TS,Mar?ais G,Roberts M,Subramanian P,Yorke JA,Salzberg SL

Suppression of connexin 43 and E-cadherin transcripts in in vitro derived bovine embryos following culture in vitro or in vivo in the homologous bovine oviduct.
Molecular reproduction and development74(8)978-88(2007 Aug)
Tesfaye D,Lonergan P,Hoelker M,Rings F,Nganvongpanit K,Havlicek V,Besenfelder U,Jennen D,Tholen E,Schellander K

The cytoplasmic expression of E-cadherin and beta-catenin in bovine trophoblasts during binucleate cell differentiation.
Placenta26(5)393-401(2005 May)
Nakano H,Shimada A,Imai K,Takahashi T,Hashizume K

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

CDH1 cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報