STAT5A cDNA ORF clone, Bos taurus(cattle)

Gene
Clones
gRNAs

Summary

Gene Symbol	STAT5A
Entrez Gene ID	282375
Full Name	signal transducer and activator of transcription 5A
Synonyms	STAT5A/MGF,STATA5
General protein information	Preferred Names signal transducer and activator of transcription 5A Names signal transducer and activator of transcription 5A STAT5A, Mammary Gland Factor mammary gland factor signal transducer and activator of transcription factor 5A
Gene Type	protein-coding
Organism	Bos taurus(cattle)
Genome	Chromosome: 19 Map Location: 19q17

mRNA and Protein(s)

mRNA	Protein	Name
NM_001012673.1	NP_001012691.1	signal transducer and activator of transcription 5A

Pathways from BioSystems

Homologies

Pan troglodytes (chimpanzee)	STAT5A	XP_001165870.1
	STAT5A	XP_002800522.1
Anopheles gambiae (African malaria mosquito)	STAT2	XP_311053.3
Anopheles gambiae (African malaria mosquito)	STAT_ANOGA	XP_311525.1
Bos taurus (cattle)	STAT5A	NP_001012691.1
Homo sapiens (human)	STAT5A	NP_003143.2
Mus musculus (house mouse)	Stat5a	NP_035618.1
Rattus norvegicus (Norway rat)	Stat5a	NP_058760.1
Canis lupus familiaris (dog)	STAT5A	XP_859906.1

Gene Ontology
Bibliography

Related articles in PubMed

Association of STAT5A Gene Variants with Milk Production Traits in Agerolese Cattle.
Selvaggi M, Albarella S, Dario C, Peretti V, Ciotola F
Biochemical genetics55(2)158-167(2017 Apr)

Association between polymorphisms in somatotropic axis genes and fertility of Holstein dairy cows.
Hax LT, Schneider A, Jacometo CB, Mattei P, da Silva TC, Farina G, Corr?a MN
Theriogenology8867-72(2017 Jan)

INVESTIGATION OF STAT5A, FSHR AND LHR GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS (EAST ANATOLLAN RED, SOUTH ANATOLIAN RED, TURKISH GREY, ANATOLIAN BLACK AND ZAVOT).
Arslan K, Aky?z B, Agaoglu OK
Genetika51(11)1264-72(2015 Nov)

Methionyl-Methionine Promotes ?-s1 Casein Synthesis in Bovine Mammary Gland Explants by Enhancing Intracellular Substrate Availability and Activating JAK2-STAT5 and mTOR-Mediated Signaling Pathways.
Yang JX, Wang CH, Xu QB, Zhao FQ, Liu JX, Liu HY
The Journal of nutrition145(8)1748-53(2015 Aug)

Genetic effects of single nucleotide polymorphisms in JAK2 and STAT5A genes on susceptibility of Chinese Holsteins to mastitis.
Usman T, Yu Y, Liu C, Wang X, Zhang Q, Wang Y
Molecular biology reports41(12)8293-301(2014 Dec)

GeneRIFs: Gene References Into Functions What's a GeneRIF?

Milk production traits were analyzed for each animal in the first, second, third, and fourth lactation. No genetic variability was found at STAT5A/AvaI locus. At STAT5A/MslI locus, the frequencies of T and C alleles were 0.875 and 0.125, respectively. Significant differences between genotypes were found
Title: Association of STAT5A Gene Variants with Milk Production Traits in Agerolese Cattle.

There was no association between the genotypes of GH and IGF-IS and fertility of Holstein cows raised in semiextensive or intensive regimes, while the STAT5 ABstEII polymorphism was associated with calving-first heat interval in Holstein cows raised in the intensive system.
Title: Association between polymorphisms in somatotropic axis genes and fertility of Holstein dairy cows.

INVESTIGATION OF STAT5A, FSHR AND LHR GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS
Title: INVESTIGATION OF STAT5A, FSHR AND LHR GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS (EAST ANATOLLAN RED, SOUTH ANATOLIAN RED, TURKISH GREY, ANATOLIAN BLACK AND ZAVOT).

The embryonic STAT5A gene is primarily activated by maternal gene products and the most abundant STAT5A expression occurred at the 2-cell stage blastocysts.
Title: Expression pattern of STAT5A gene during early bovine embryogenesis.

Results indicate that SNPs in STAT5A and JAK2 genes were associated with somatic cell count and score in milk and cytokines but none of the SNP was associated with milk production traits suggesting an important role in immunity.
Title: Genetic effects of single nucleotide polymorphisms in JAK2 and STAT5A genes on susceptibility of Chinese Holsteins to mastitis.

The following STAT5A gene cDNA ORF clone sequences were retrieved from the NCBI Reference Sequence Database (RefSeq). These sequences represent the protein coding region of the STAT5A cDNA ORF which is encoded by the open reading frame (ORF) sequence. ORF sequences can be delivered in our standard vector, pcDNA3.1⁺/C-(K)DYK or the vector of your choice as an expression/transfection-ready ORF clone. Not the clone you want? Click here to find your clone.

***CloneID	Accession No.	Definition	**Vector	*Turnaround time	Price (USD)	Select
OBa41681	NM_001012673.1 Latest version!	Bos taurus signal transducer and activator of transcription 5A (STAT5A), mRNA.	pcDNA3.1-C-(k)DYK or customized vector	12-14	$426.30 $609.00

ORF Online Only Promotion

Next-day Shipping ORF Clones ( in default vector with tag)
1 Clone	30% OFF
2-4 Clone	40% OFF
5 or more Clone	50% OFF
All Other ORF Clones
30% OFF

*Business Day

** You may select a custom vector to replace pcDNA3.1+/C-(K)DYK after clone is added to cart.

** GenScript guarantees 100% sequence accuracy of all synthetic DNA constructs we deliver, but we do not guarantee protein expression in your experimental system. Protein expression is influenced by many factors that may vary between experiments or laboratories. In addition, please pay attention to the signal peptide, propeptide and transit peptide in target ORF, which may affect the choice of vector (N/C terminal tag vector).

***One clone ID might be correlated to multiple accession numbers, which share the same CDS sequence.

Reference Sequences (Refseq)

STAT5A ( NM_001012673.1 ) cDNA ORF clone, Bos taurus(cattle) -> NP_001012691.1 Bos taurus signal transducer and activator of transcription 5A (STAT5A), mRNA.

Price & Availability↑

CloneID	OBa41681
Clone ID Related Accession (Same CDS sequence)	NM_001012673.1
Accession Version	NM_001012673.1 Latest version!	Documents for ORF clone product in default vector
Sequence Information	ORF Nucleotide Sequence (Length: 2385bp) Protein sequence SNP
Vector	pcDNA3.1-C-(k)DYK or customized vector	User Manual
Clone information	Clone Map	MSDS
Tag on pcDNA3.1⁺/C-(K)DYK	C terminal DYKDDDDK tags
ORF Insert Method	CloneEZ™ Seamless cloning technology
Insert Structure	linear
Update Date	2019-02-16
Organism	Bos taurus(cattle)
Product	signal transducer and activator of transcription 5A
Comment	Comment: PROVISIONAL REFSEQ: This record has not yet been subject to final NCBI review. The reference sequence was derived from Z72482.1. On Mar 29, 2005 this sequence version replaced XM_599297.1. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Gene record to access additional publications. ##Evidence-Data-START## Transcript exon combination :: Z72482.1 [ECO:0000332] RNAseq introns :: single sample supports all introns SAMN03145413, SAMN03145415 [ECO:0000348] ##Evidence-Data-END##

ATGGCGGGCT GGATCCAGGC CCAGCAGCTG CAGGGAGATG CCCTGCGCCA GATGCAGGTG 
CTATACGGGC AGGACTTCCC CATCGAGGTC CGGCATTACT TGGCACAGTG GATTGAGAGC 
CAGCCGTGGG ATGCCATCGA CCTGGACAAT CCCCAGGACC GGGCCCAGGC CACCCAGCTC 
CTGGAGGGCC TGGTGCAGGA GTTGCAGAAG AAGGCAGAGC ACCAAGTCGG GGAAGACGGG 
TTCCTTCTGA AGATCAAGCT GGGGCACTAT GCCACGCAGC TCCAGAACAC GTACGACCGC 
TGCCCCATGG AGCTGGTGCG CTGCATTCGC CACATTCTGT ACAATGAACA GAGGCTGGTC 
CGAGAAGCCA ACAATGGTAG TTCTTCTGCT GGGATCCTGG TTGATGCCAT GTCCCAGAAA 
CACCTTCAGA TCAACCAGAC ATTTGAGGAA CTGCGACTGG TCACGCAGGA CACAGAGAAT 
GAGCTGAAGA AGCTGCAGCA GACTCAAGAG TATTTCATCA TCCAGTATCA GGAGAGCCTG 
AGGATCCAGG CTCAGTTTGC CCAGCTGGCC CAGCTGAACC CCCAGGAGCG ACTGAGCCGG 
GAGACGGCCC TCCAGCAGAA GCAGGTGTCC CTGGAGGCCT GGCTGCAGCG CGAGGCCCAG 
ACGCTGCAGC AGTACCGCGT GGAGCTGGCT GAGAAGCACC AGAAGACCCT GCAGCTGCTG 
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG 
CTGGCGGGGA ACGGAGGGCC CCCCGAGGGC AGCCTGGATG TGCTACAGTC CTGGTGTGAG 
AAGTTGGCGG AGATTATCTG GCAGAACCGG CAGCAGATCC GCAGAGCCGA GCACCTCTGC 
CAGCAGCTGC CCATCCCCGG CCCCGTGGAG GAGATGCTGG CTGAGGTCAA CGCCACCATC 
ACTGACATCA TCTCAGCCCT GGTGACCAGC ACCTTCATCA TCGAGAAGCA GCCCCCTCAG 
GTCCTGAAGA CCCAGACCAA GTTCGCGGCC ACCGTGCGCC TGCTGGTGGG TGGGAAGCTG 
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGCGAGCA GCAGGCCAAG 
TCACTGCTCA AGAACGAGAA CACCCGCAAT GAGTGCAGCG GGGAGATCCT GAACAACTGC 
TGTGTGATGG AGTATCACCA GGCCACAGGC ACCCTCAGCG CCCACTTCAG AAACATGTCC 
CTCAAGAGGA TCAAGCGAGC TGACCGGCGA GGTGCAGAGT CTGTGACGGA AGAGAAGTTC 
ACGGTCCTGT TTGAGTCTCA ATTCAGTGTT GGCAGCAATG AGCTTGTGTT CCAGGTGAAG 
ACCCTGTCCC TTCCCGTGGT TGTCATCGTT CATGGCAGCC AGGACCACAA TGCTACTGCC 
ACGGTGCTGT GGGACAATGC CTTTGCTGAG CCGGGCAGGG TGCCGTTTGC GGTGCCCGAC 
AAAGTCTTGT GGCCGCAGCT GTGCGAGGCG CTCAACATGA AATTCAAGGC CGAGGTGCAG 
AGCAACCGGG GCCTGACCAA GGAGAACCTG GTGTTCCTGG CGCAGAAGCT GTTCAACAGC 
AGCAGCAGCC ATCTCGAGGA CTACAACGGC ATGTCCGTGT CCTGGTCCCA GTTCAACCGG 
GAGAACTTGC CCGGCTGGAA CTACACCTTC TGGCAGTGGT TCGACGGGGT CATGGAGGTG 
CTGAAGAAAC ATCACAAGCC CCATTGGAAT GACGGGGCCA TCCTAGGTTT TGTGAACAAG 
CAACTGGCCC ATGACCTGCT CATCAACAAG CCCGACGGTA CCTTCTTGAT GCGCTTCAGC 
GACTCAGAAA TTGGGGGCAT CACCATCGCC TGGAAGTTTG ACTCTCCTGA CCGTAACCTG 
TGGAATCTGA AGCCATTCAC CACGCGGGAT TTCTCCATCC GATCCCTGGC CGACAGGTTG 
GGGGACCTGA ACTATCTCAT CTACGTGTTT CCCGACCGGC CCAAGGATGA GGTCTTCTCC 
AAGTACTACA CTCCTGTGCT TGCTAAAGCA GTGGACGGAT ACGTGAAGCC ACAGATCAAG 
CAAGTGGTCC CTGAGTTTGT GAGCGCCTCT GCAGACTCTG CTGGAAGCAA CGCCACCTAC 
ATGGACCAGG CTCCTTCCCC AGCCGTGTGC CCCCAGCCTC ACTATAACAT GTACCCACAG 
AACCCTGACC CGGTGCTCGA CCAGGATGGA GAATTCGACC TGGACGAGAC CATGGATGTG 
GCCCGGCACG TGGAAGAACT CCTCCGCCGC CCAATGGACA GTCTGGAGCC CTCTCTCCCC 
CCGCCCACTG GTCTCTTTAC CCCCGGCAGA GGCTCGCTGT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

RefSeq	NP_001012691.1
CDS	69..2453
Translation	MAGWIQAQQLQGDALRQMQVLYGQDFPIEVRHYLAQWIESQPWDAIDLDNPQDRAQATQLLEGLVQELQKKAEHQVGEDGFLLKIKLGHYATQLQNTYDRCPMELVRCIRHILYNEQRLVREANNGSSSAGILVDAMSQKHLQINQTFEELRLVTQDTENELKKLQQTQEYFIIQYQESLRIQAQFAQLAQLNPQERLSRETALQQKQVSLEAWLQREAQTLQQYRVELAEKHQKTLQLLRKQQTIILDDELIQWKRRQQLAGNGGPPEGSLDVLQSWCEKLAEIIWQNRQQIRRAEHLCQQLPIPGPVEEMLAEVNATITDIISALVTSTFIIEKQPPQVLKTQTKFAATVRLLVGGKLNVHMNPPQVKATIISEQQAKSLLKNENTRNECSGEILNNCCVMEYHQATGTLSAHFRNMSLKRIKRADRRGAESVTEEKFTVLFESQFSVGSNELVFQVKTLSLPVVVIVHGSQDHNATATVLWDNAFAEPGRVPFAVPDKVLWPQLCEALNMKFKAEVQSNRGLTKENLVFLAQKLFNSSSSHLEDYNGMSVSWSQFNRENLPGWNYTFWQWFDGVMEVLKKHHKPHWNDGAILGFVNKQLAHDLLINKPDGTFLMRFSDSEIGGITIAWKFDSPDRNLWNLKPFTTRDFSIRSLADRLGDLNYLIYVFPDRPKDEVFSKYYTPVLAKAVDGYVKPQIKQVVPEFVSASADSAGSNATYMDQAPSPAVCPQPHYNMYPQNPDPVLDQDGEFDLDETMDVARHVEELLRRPMDSLEPSLPPPTGLFTPGRGSLS

Target ORF information:

RefSeq Version	NM_001012673.1
Organism	Bos taurus(cattle)
Definition	Bos taurus signal transducer and activator of transcription 5A (STAT5A), mRNA.

Target ORF information:

Epitope	DYKDDDDK
Bacterial selection	AMP^R
Mammalian selection	Neo^R
Vector	pcDNA3.1⁺/C-(K)DYK

NM_001012673.1

ORF Insert Sequence:

ATGGCGGGCT GGATCCAGGC CCAGCAGCTG CAGGGAGATG CCCTGCGCCA GATGCAGGTG 
CTATACGGGC AGGACTTCCC CATCGAGGTC CGGCATTACT TGGCACAGTG GATTGAGAGC 
CAGCCGTGGG ATGCCATCGA CCTGGACAAT CCCCAGGACC GGGCCCAGGC CACCCAGCTC 
CTGGAGGGCC TGGTGCAGGA GTTGCAGAAG AAGGCAGAGC ACCAAGTCGG GGAAGACGGG 
TTCCTTCTGA AGATCAAGCT GGGGCACTAT GCCACGCAGC TCCAGAACAC GTACGACCGC 
TGCCCCATGG AGCTGGTGCG CTGCATTCGC CACATTCTGT ACAATGAACA GAGGCTGGTC 
CGAGAAGCCA ACAATGGTAG TTCTTCTGCT GGGATCCTGG TTGATGCCAT GTCCCAGAAA 
CACCTTCAGA TCAACCAGAC ATTTGAGGAA CTGCGACTGG TCACGCAGGA CACAGAGAAT 
GAGCTGAAGA AGCTGCAGCA GACTCAAGAG TATTTCATCA TCCAGTATCA GGAGAGCCTG 
AGGATCCAGG CTCAGTTTGC CCAGCTGGCC CAGCTGAACC CCCAGGAGCG ACTGAGCCGG 
GAGACGGCCC TCCAGCAGAA GCAGGTGTCC CTGGAGGCCT GGCTGCAGCG CGAGGCCCAG 
ACGCTGCAGC AGTACCGCGT GGAGCTGGCT GAGAAGCACC AGAAGACCCT GCAGCTGCTG 
CGGAAGCAGC AGACCATCAT CCTGGATGAC GAGCTGATCC AGTGGAAGCG GCGGCAGCAG 
CTGGCGGGGA ACGGAGGGCC CCCCGAGGGC AGCCTGGATG TGCTACAGTC CTGGTGTGAG 
AAGTTGGCGG AGATTATCTG GCAGAACCGG CAGCAGATCC GCAGAGCCGA GCACCTCTGC 
CAGCAGCTGC CCATCCCCGG CCCCGTGGAG GAGATGCTGG CTGAGGTCAA CGCCACCATC 
ACTGACATCA TCTCAGCCCT GGTGACCAGC ACCTTCATCA TCGAGAAGCA GCCCCCTCAG 
GTCCTGAAGA CCCAGACCAA GTTCGCGGCC ACCGTGCGCC TGCTGGTGGG TGGGAAGCTG 
AACGTGCACA TGAACCCCCC CCAGGTGAAG GCCACCATCA TCAGCGAGCA GCAGGCCAAG 
TCACTGCTCA AGAACGAGAA CACCCGCAAT GAGTGCAGCG GGGAGATCCT GAACAACTGC 
TGTGTGATGG AGTATCACCA GGCCACAGGC ACCCTCAGCG CCCACTTCAG AAACATGTCC 
CTCAAGAGGA TCAAGCGAGC TGACCGGCGA GGTGCAGAGT CTGTGACGGA AGAGAAGTTC 
ACGGTCCTGT TTGAGTCTCA ATTCAGTGTT GGCAGCAATG AGCTTGTGTT CCAGGTGAAG 
ACCCTGTCCC TTCCCGTGGT TGTCATCGTT CATGGCAGCC AGGACCACAA TGCTACTGCC 
ACGGTGCTGT GGGACAATGC CTTTGCTGAG CCGGGCAGGG TGCCGTTTGC GGTGCCCGAC 
AAAGTCTTGT GGCCGCAGCT GTGCGAGGCG CTCAACATGA AATTCAAGGC CGAGGTGCAG 
AGCAACCGGG GCCTGACCAA GGAGAACCTG GTGTTCCTGG CGCAGAAGCT GTTCAACAGC 
AGCAGCAGCC ATCTCGAGGA CTACAACGGC ATGTCCGTGT CCTGGTCCCA GTTCAACCGG 
GAGAACTTGC CCGGCTGGAA CTACACCTTC TGGCAGTGGT TCGACGGGGT CATGGAGGTG 
CTGAAGAAAC ATCACAAGCC CCATTGGAAT GACGGGGCCA TCCTAGGTTT TGTGAACAAG 
CAACTGGCCC ATGACCTGCT CATCAACAAG CCCGACGGTA CCTTCTTGAT GCGCTTCAGC 
GACTCAGAAA TTGGGGGCAT CACCATCGCC TGGAAGTTTG ACTCTCCTGA CCGTAACCTG 
TGGAATCTGA AGCCATTCAC CACGCGGGAT TTCTCCATCC GATCCCTGGC CGACAGGTTG 
GGGGACCTGA ACTATCTCAT CTACGTGTTT CCCGACCGGC CCAAGGATGA GGTCTTCTCC 
AAGTACTACA CTCCTGTGCT TGCTAAAGCA GTGGACGGAT ACGTGAAGCC ACAGATCAAG 
CAAGTGGTCC CTGAGTTTGT GAGCGCCTCT GCAGACTCTG CTGGAAGCAA CGCCACCTAC 
ATGGACCAGG CTCCTTCCCC AGCCGTGTGC CCCCAGCCTC ACTATAACAT GTACCCACAG 
AACCCTGACC CGGTGCTCGA CCAGGATGGA GAATTCGACC TGGACGAGAC CATGGATGTG 
GCCCGGCACG TGGAAGAACT CCTCCGCCGC CCAATGGACA GTCTGGAGCC CTCTCTCCCC 
CCGCCCACTG GTCTCTTTAC CCCCGGCAGA GGCTCGCTGT CCTGA

The stop codons will be deleted if pcDNA3.1⁺/C-(K)DYK vector is selected.

PubMed

Association of STAT5A Gene Variants with Milk Production Traits in Agerolese Cattle.
Biochemical genetics55(2)158-167(2017 Apr)
Selvaggi M,Albarella S,Dario C,Peretti V,Ciotola F

Association between polymorphisms in somatotropic axis genes and fertility of Holstein dairy cows.
Theriogenology8867-72(2017 Jan)
Hax LT,Schneider A,Jacometo CB,Mattei P,da Silva TC,Farina G,Corr?a MN

INVESTIGATION OF STAT5A, FSHR AND LHR GENE POLYMORPHISMS IN TURKISH INDIGENOUS CATTLE BREEDS (EAST ANATOLLAN RED, SOUTH ANATOLIAN RED, TURKISH GREY, ANATOLIAN BLACK AND ZAVOT).
Genetika51(11)1264-72(2015 Nov)
Arslan K,Aky?z B,Agaoglu OK

Methionyl-Methionine Promotes ?-s1 Casein Synthesis in Bovine Mammary Gland Explants by Enhancing Intracellular Substrate Availability and Activating JAK2-STAT5 and mTOR-Mediated Signaling Pathways.
The Journal of nutrition145(8)1748-53(2015 Aug)
Yang JX,Wang CH,Xu QB,Zhao FQ,Liu JX,Liu HY

Genetic effects of single nucleotide polymorphisms in JAK2 and STAT5A genes on susceptibility of Chinese Holsteins to mastitis.
Molecular biology reports41(12)8293-301(2014 Dec)
Usman T,Yu Y,Liu C,Wang X,Zhang Q,Wang Y

見積依頼

Eメール

japanmarket@genscript.com

電話

03-6811-6572

FAX

03-6811-6573
050-3174-7589(受注専用)

オンラインフォーム

オンライン注文

STAT5A cDNA ORF clone, Bos taurus(cattle)

Gene

Clones

gRNAs

Related articles in PubMed

Target ORF information:

Target ORF information:

ORF Insert Sequence:

見積依頼

Eメール

電話

FAX

オンラインフォーム

サポート

会社情報

サポート

会社情報